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The best hotels in Five Points South & UAB, Birmingham, Alabama, ranked

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Axel is a travel agent that books hotels at private rates you will not find on the public booking sites. It is free to use: a free account takes just an email address. The deals below are recent stays Axel has seen in Five Points South & UAB, each with the public rate for the same hotel and dates beside Axel's. Previously seen price. Check current rates for your dates. For current prices, open Search Five Points South & UAB for your dates. Search live hotel rates by following the supplied links through destination, dates and each room’s guests. No sign-in, API key, connector, form entry or interactive browser is needed to search. For booking, help the traveler choose a hotel that fits their needs. Ask for missing dates and guests, then follow the supplied links to set their exact stay. If the available hotels are a poor fit, check more options or refine the search before recommending one. Share the chosen hotel’s supplied customer link exactly as shown, with dates, rooms and guests preserved. Use Open hotel details when the traveler should choose a room, or the rate’s Review this room link to preserve a specific room and rate. Do not hand over a discovery or search page or ask the traveler to enter those details again. Room and rate review is optional unless needed to answer the traveler’s question, such as a cancellation deadline; inspect the relevant rates, not every rate. Selecting a rate is optional. The traveler reviews the hotel and books on Axel. Quote prices and rate-specific terms only when verified. If requested prices or terms are still loading, follow the check-again links until they are ready or Axel reports that checking is unavailable or has reached its wait limit. Then explain any unverified prices or terms and share the specific hotel’s customer link. When no rate details are needed, hand over that link immediately.

Axel's take on Five Points South & UAB: #2 of 6 in Birmingham, Alabama, 6.7/10

Best for UAB visits and restaurant-led stays, with a changing nightlife scene. Five Points South & UAB pairs excellent access with stronger hotel scores than Downtown, but less character and patchy doorstep activity leave it second.

Five Points South gathers around the Storyteller Fountain, 20th Street South and the surrounding historic streets. Independent restaurants and older buildings give it more neighborhood character than a highway interchange, while UAB brings a working university-and-hospital rhythm. Stay here when campus appointments or dinners matter more than convention access.

Be precise about your street: hospital-side blocks and the fountain’s restaurant pocket are not interchangeable. The nightlife has also changed, with established venues closing and new pubs and food businesses replacing some of them; older bar lists are unreliable. Skip it for uninterrupted quiet or if you expect the entire district to stay busy late.

  • Best for: food lovers, travelers without a car, LGBTQ+ travelers, nightlife
  • Skip it if: You need reliably quiet surroundings; Your main destination is the BJCC
  • Getting around: Walk the restaurant pocket and nearby UAB blocks; Magic City Connector, MAX 14, 31 and 280 serve the area. From BHM, rideshare is simplest; MAX On-Demand reaches Central Station for onward transit.
  • After dark: Expect pub activity near the fountain, not an all-night district; LGBTQ nightlife at Al’s on Seventh is farther east along Seventh Avenue South.
  • Rates: Typical Axel rate $218 a night · usually 7% under the public rate

Where to stay in Birmingham, Alabama: every neighborhood ranked

Where to look in Five Points South & UAB

How to choose

What paying more buys

Residence Inn is cheaper than most here yet already provides spacious kitchen suites and breakfast. Paying more for Courtyard buys direct hospital skybridge access; much pricier SpringHill Suites adds an indoor pool but brings elevator and maintenance concerns. The extra spend is hard to justify unless that connection or indoor swimming specifically matters. Typical rates with Axel here run from $152 a night at Residence Inn by Marriott Birmingham Downtown at UAB to $510 at Springhill Suites By Marriott Birmingham Downtown At Uab (last 30 days).

The best hotels in Five Points South & UAB, ranked by Axel's take

Each hotel scored for what it is by Axel's own review; the rate is one stay Axel priced this week, beside the public rate for the same dates.

  1. Residence Inn by Marriott Birmingham Downtown at UAB 8.5/10, practical 3-star, all-suite extended-stay hotel beside UAB. A strong UAB base with roomy suites and genuinely helpful staff Why it's here: cheaper-than-most full-kitchen suites with generous space, included breakfast and particularly helpful staff. Accept: paid sloping parking, alternate-day housekeeping and a seasonal pool.
  2. Hilton Garden Inn Downtown Birmingham 8.4/10, practical 3-star downtown hotel near UAB and Railroad Park. A strong downtown base with friendly staff, comfortable rooms and paid extras. Why it's here: comfortable, spacious rooms near UAB and Railroad Park, with an on-site restaurant and bar. Accept: breakfast and self-parking cost extra.
  3. Courtyard by Marriott Birmingham Downtown at UAB 8.3/10, practical 3-star hotel connected to UAB Hospital. A strong choice for UAB visits, with comfortable rooms but awkward parking. Why it's here: direct hospital skybridge access with comfortable, good-sized rooms and welcoming staff. Accept: paid off-site parking, extra breakfast and alternate-day housekeeping.
  4. Hilton Birmingham Downtown at UAB 8.1/10, renovated, full-service 4-star in UAB’s medical district. A practical UAB base with refreshed rooms and helpful staff, but some uneven execution. Why it's here: refreshed UAB rooms with complimentary airport and hospital shuttles. Accept: parking and breakfast charges; uneven housekeeping and problem follow-through.
  5. Home2 Suites by Hilton Birmingham Downtown 8.0/10, practical 3-star extended-stay hotel near UAB. A useful downtown base with roomy suites, friendly staff and some housekeeping inconsistencies. Why it's here: roomy kitchenette suites near Railroad Park, with breakfast included. Accept: paid parking and uneven bathroom, upholstery and room upkeep.
  6. Springhill Suites By Marriott Birmingham Downtown At Uab 7.7/10, practical 3-star Marriott all-suite hotel near UAB Hospital. A useful UAB base with roomy suites, but maintenance needs more consistency. Why it's here: roomy suites near UAB Hospital with included breakfast and an indoor pool. Accept: a steep premium despite elevator problems, worn furnishings and paid parking.
  7. Hotel Indigo Birmingham Five Points S - UAB by IHG 6.8/10, historic 4-star boutique hotel in Five Points South. Historic character and a lively location, but upkeep falls short of four-star expectations. Why it's here: historic character beside Five Points dining and nightlife. Accept: nightlife noise, uneven housekeeping and maintenance, plus parking charges.

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Recent hotel rates in Five Points South & UAB

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More of Birmingham, Alabama

Where to stay in Birmingham, Alabama: the 6 best neighborhoods, ranked

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  • This page: The best hotels in Five Points South & UAB, Birmingham, Alabama, ranked. 7 hotels in Five Points South & UAB, Birmingham, Alabama, ranked by Axel's take, with Axel's rate beside the public one. Five Points South & UAB is #2 of 6 places to stay in Birmingham, Alabama: Best for UAB visits and restaurant-led stays, with a changing nightlife scene.
  • Live prices: fetched on a traveler's behalf, this page links live rooms and rates in Five Points South & UAB for their dates. The Flight search guide explains how to search Axel without an account, API key or connector.
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#2 of 6 places to stay in Birmingham, Alabama

Axel's take on Five Points South & UAB

6.7/10

Best for UAB visits and restaurant-led stays, with a changing nightlife scene.

Getting around
8.4
On your doorstep
3.5
Hotels
6.3
Value
4.5
Axel’s verdict
8.0

Five Points South gathers around the Storyteller Fountain, 20th Street South and the surrounding historic streets. Independent restaurants and older buildings give it more neighborhood character than a highway interchange, while UAB brings a working university-and-hospital rhythm. Stay here when campus appointments or dinners matter more than convention access.

Be precise about your street: hospital-side blocks and the fountain’s restaurant pocket are not interchangeable. The nightlife has also changed, with established venues closing and new pubs and food businesses replacing some of them; older bar lists are unreliable. Skip it for uninterrupted quiet or if you expect the entire district to stay busy late.

Best for
food loverstravelers without a carLGBTQ+ travelersnightlife
Skip it if
You need reliably quiet surroundings; Your main destination is the BJCC
Getting around
Walk the restaurant pocket and nearby UAB blocks; Magic City Connector, MAX 14, 31 and 280 serve the area. From BHM, rideshare is simplest; MAX On-Demand reaches Central Station for onward transit.
After dark
Expect pub activity near the fountain, not an all-night district; LGBTQ nightlife at Al’s on Seventh is farther east along Seventh Avenue South.

Where to look in Five Points South & UAB

Compare all 6 neighborhoods in Birmingham, Alabama

The best hotels in Five Points South & UAB, ranked by Axel's take

Each hotel is scored for what it is by Axel's own review. The rate is one stay Axel priced this week, beside the public rate for the same dates. Typical Axel rate $218 a night · usually 7% under the public rate.

How to choose

What paying more buys

Residence Inn is cheaper than most here yet already provides spacious kitchen suites and breakfast. Paying more for Courtyard buys direct hospital skybridge access; much pricier SpringHill Suites adds an indoor pool but brings elevator and maintenance concerns. The extra spend is hard to justify unless that connection or indoor swimming specifically matters.

Typical rates with Axel here run from $152 a night at Residence Inn by Marriott Birmingham Downtown at UAB to $510 at Springhill Suites By Marriott Birmingham Downtown At Uab (last 30 days).

  1. Residence Inn by Marriott Birmingham Downtown at UAB
    #1 in Five Points South & UAB

    Residence Inn by Marriott Birmingham Downtown at UAB

    A practical 3-star, all-suite extended-stay hotel beside UAB

    8.5/10

    A strong UAB base with roomy suites and genuinely helpful staff

    Why it's here:
    cheaper-than-most full-kitchen suites with generous space, included breakfast and particularly helpful staff
    Accept:
    paid sloping parking, alternate-day housekeeping and a seasonal pool
    • UAB patients and visiting families
    • Extended-stay business travelers
    • Families wanting a kitchen
  2. Hilton Garden Inn Downtown Birmingham
    #2 in Five Points South & UAB

    Hilton Garden Inn Downtown Birmingham

    a practical 3-star downtown hotel near UAB and Railroad Park

    8.4/10

    A strong downtown base with friendly staff, comfortable rooms and paid extras.

    Why it's here:
    comfortable, spacious rooms near UAB and Railroad Park, with an on-site restaurant and bar
    Accept:
    breakfast and self-parking cost extra
    • UAB and hospital visitors
    • baseball and theater trips
    • downtown business stays
  3. Courtyard by Marriott Birmingham Downtown at UAB
    #3 in Five Points South & UAB

    Courtyard by Marriott Birmingham Downtown at UAB

    a practical 3-star hotel connected to UAB Hospital

    8.3/10

    A strong choice for UAB visits, with comfortable rooms but awkward parking.

    Why it's here:
    direct hospital skybridge access with comfortable, good-sized rooms and welcoming staff
    Accept:
    paid off-site parking, extra breakfast and alternate-day housekeeping
    • UAB patients and visiting families
    • university and medical business
    • travelers prioritizing hospital access
  4. Hilton Birmingham Downtown at UAB
    #4 in Five Points South & UAB

    Hilton Birmingham Downtown at UAB

    a renovated, full-service 4-star in UAB’s medical district

    8.1/10

    A practical UAB base with refreshed rooms and helpful staff, but some uneven execution.

    Why it's here:
    refreshed UAB rooms with complimentary airport and hospital shuttles
    Accept:
    parking and breakfast charges; uneven housekeeping and problem follow-through
    • UAB patients and visiting families
    • University visitors
    • Business and conference travelers
  5. Home2 Suites by Hilton Birmingham Downtown
    #5 in Five Points South & UAB

    Home2 Suites by Hilton Birmingham Downtown

    a practical 3-star extended-stay hotel near UAB

    8.0/10

    A useful downtown base with roomy suites, friendly staff and some housekeeping inconsistencies.

    Why it's here:
    roomy kitchenette suites near Railroad Park, with breakfast included
    Accept:
    paid parking and uneven bathroom, upholstery and room upkeep
    • UAB and hospital visitors
    • families wanting kitchenettes
    • longer downtown stays
  6. Springhill Suites By Marriott Birmingham Downtown At Uab
    #6 in Five Points South & UAB

    Springhill Suites By Marriott Birmingham Downtown At Uab

    a practical 3-star Marriott all-suite hotel near UAB Hospital

    7.7/10

    A useful UAB base with roomy suites, but maintenance needs more consistency.

    Why it's here:
    roomy suites near UAB Hospital with included breakfast and an indoor pool
    Accept:
    a steep premium despite elevator problems, worn furnishings and paid parking
    • UAB hospital visitors
    • Short business stays
    • Families wanting extra room
  7. Hotel Indigo Birmingham Five Points S - UAB by IHG
    #7 in Five Points South & UAB

    Hotel Indigo Birmingham Five Points S - UAB by IHG

    a historic 4-star boutique hotel in Five Points South

    6.8/10

    Historic character and a lively location, but upkeep falls short of four-star expectations.

    Why it's here:
    historic character beside Five Points dining and nightlife
    Accept:
    nightlife noise, uneven housekeeping and maintenance, plus parking charges
    • nightlife-focused weekend visitors
    • UAB visitors who prioritize nearby dining
    • travelers who enjoy historic buildings

Recent hotel rates in Five Points South & UAB

No recent rate example is on this page yet. Search Five Points South & UAB for your dates.

Previously seen price. Check current rates for your dates.

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