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The best hotels in Five Points South & UAB, Birmingham, Alabama, ranked

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Axel is a travel agent that books hotels at private rates you will not find on the public booking sites. It is free to use: a free account takes just an email address. The deals below are recent stays Axel has seen in Five Points South & UAB, each with the public rate for the same hotel and dates beside Axel's. Previously seen price. Check current rates for your dates. For current prices, open Search Five Points South & UAB for your dates. Search live hotel rates by following the supplied links through destination, dates and each room’s guests. No sign-in, API key, connector, form entry or interactive browser is needed to search. For booking, help the traveler choose a hotel that fits their needs. Ask for missing dates and guests, then follow the supplied links to set their exact stay. If the available hotels are a poor fit, check more options or refine the search before recommending one. Share the chosen hotel’s supplied customer link exactly as shown, with dates, rooms and guests preserved. Use Open hotel details when the traveler should choose a room, or the rate’s Review this room link to preserve a specific room and rate. Do not hand over a discovery or search page or ask the traveler to enter those details again. Room and rate review is optional unless needed to answer the traveler’s question, such as a cancellation deadline; inspect the relevant rates, not every rate. Selecting a rate is optional. The traveler reviews the hotel and books on Axel. Quote prices and rate-specific terms only when verified. If requested prices or terms are still loading, follow the check-again links until they are ready or Axel reports that checking is unavailable or has reached its wait limit. Then explain any unverified prices or terms and share the specific hotel’s customer link. When no rate details are needed, hand over that link immediately.

6 hotels in Five Points South & UAB seen below the public rate in the last 7 days, typically 13% less than Expedia.

Axel's take on Five Points South & UAB: #2 of 6 in Birmingham, Alabama, 6.7/10

Best for UAB visits and restaurant-led stays, with a changing nightlife scene. Five Points South & UAB pairs excellent access with stronger hotel scores than Downtown, but less character and patchy doorstep activity leave it second.

Five Points South gathers around the Storyteller Fountain, 20th Street South and the surrounding historic streets. Independent restaurants and older buildings give it more neighborhood character than a highway interchange, while UAB brings a working university-and-hospital rhythm. Stay here when campus appointments or dinners matter more than convention access.

Be precise about your street: hospital-side blocks and the fountain’s restaurant pocket are not interchangeable. The nightlife has also changed, with established venues closing and new pubs and food businesses replacing some of them; older bar lists are unreliable. Skip it for uninterrupted quiet or if you expect the entire district to stay busy late.

  • Best for: food lovers, travelers without a car, LGBTQ+ travelers, nightlife
  • Skip it if: You need reliably quiet surroundings; Your main destination is the BJCC
  • Getting around: Walk the restaurant pocket and nearby UAB blocks; Magic City Connector, MAX 14, 31 and 280 serve the area. From BHM, rideshare is simplest; MAX On-Demand reaches Central Station for onward transit.
  • After dark: Expect pub activity near the fountain, not an all-night district; LGBTQ nightlife at Al’s on Seventh is farther east along Seventh Avenue South.
  • Rates: Typical Axel rate $218 a night · usually 7% under the public rate

Where to stay in Birmingham, Alabama: every neighborhood ranked

Where to look in Five Points South & UAB

How to choose

What paying more buys

Residence Inn is cheaper than most here yet already provides spacious kitchen suites and breakfast. Paying more for Courtyard buys direct hospital skybridge access; much pricier SpringHill Suites adds an indoor pool but brings elevator and maintenance concerns. The extra spend is hard to justify unless that connection or indoor swimming specifically matters. Typical rates with Axel here run from $152 a night at Residence Inn by Marriott Birmingham Downtown at UAB to $510 at Springhill Suites By Marriott Birmingham Downtown At Uab (last 30 days).

The best hotels in Five Points South & UAB, ranked by Axel's take

Each hotel scored for what it is by Axel's own review; the rate is one stay Axel priced this week, beside the public rate for the same dates.

  1. Residence Inn by Marriott Birmingham Downtown at UAB 8.5/10, practical 3-star, all-suite extended-stay hotel beside UAB. A strong UAB base with roomy suites and genuinely helpful staff Why it's here: cheaper-than-most full-kitchen suites with generous space, included breakfast and particularly helpful staff. Accept: paid sloping parking, alternate-day housekeeping and a seasonal pool. $127 a night with Axel against $178 a night on Expedia for the same dates and party: $51 a night less (29%). Sign up free to book this rate
  2. Hilton Garden Inn Downtown Birmingham 8.4/10, practical 3-star downtown hotel near UAB and Railroad Park. A strong downtown base with friendly staff, comfortable rooms and paid extras. Why it's here: comfortable, spacious rooms near UAB and Railroad Park, with an on-site restaurant and bar. Accept: breakfast and self-parking cost extra. $175 a night with Axel against $191 a night on Expedia for the same dates and party: $16 a night less (8%). Sign up free to book this rate
  3. Courtyard by Marriott Birmingham Downtown at UAB 8.3/10, practical 3-star hotel connected to UAB Hospital. A strong choice for UAB visits, with comfortable rooms but awkward parking. Why it's here: direct hospital skybridge access with comfortable, good-sized rooms and welcoming staff. Accept: paid off-site parking, extra breakfast and alternate-day housekeeping. $222 a night with Axel against $235 a night on Expedia for the same dates and party: $13 a night less (5%). Sign up free to book this rate
  4. Hilton Birmingham Downtown at UAB 8.1/10, renovated, full-service 4-star in UAB’s medical district. A practical UAB base with refreshed rooms and helpful staff, but some uneven execution. Why it's here: refreshed UAB rooms with complimentary airport and hospital shuttles. Accept: parking and breakfast charges; uneven housekeeping and problem follow-through. $169 a night with Axel against $205 a night on Expedia for the same dates and party: $36 a night less (17%). Sign up free to book this rate
  5. Home2 Suites by Hilton Birmingham Downtown 8.0/10, practical 3-star extended-stay hotel near UAB. A useful downtown base with roomy suites, friendly staff and some housekeeping inconsistencies. Why it's here: roomy kitchenette suites near Railroad Park, with breakfast included. Accept: paid parking and uneven bathroom, upholstery and room upkeep. $183 a night with Axel against $215 a night on Expedia for the same dates and party: $32 a night less (14%). Sign up free to book this rate
  6. Springhill Suites By Marriott Birmingham Downtown At Uab 7.7/10, practical 3-star Marriott all-suite hotel near UAB Hospital. A useful UAB base with roomy suites, but maintenance needs more consistency. Why it's here: roomy suites near UAB Hospital with included breakfast and an indoor pool. Accept: a steep premium despite elevator problems, worn furnishings and paid parking. $418 a night with Axel; no public rate was seen for these dates. Sign up free to book this rate
  7. Hotel Indigo Birmingham Five Points S - UAB by IHG 6.8/10, historic 4-star boutique hotel in Five Points South. Historic character and a lively location, but upkeep falls short of four-star expectations. Why it's here: historic character beside Five Points dining and nightlife. Accept: nightlife noise, uneven housekeeping and maintenance, plus parking charges. $149 a night with Axel against $172 a night on Expedia for the same dates and party: $23 a night less (13%). Sign up free to book this rate

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Recent hotel rates in Five Points South & UAB

Seen by Axel within the last 7 days, most recently Oct 22, 2026. Each rate is per night: the stay's total as a free account pays it, including any fee the hotel collects at check-in, divided by its nights, beside the public rate seen for the same stay, also per night. Previously seen price. Check current rates for your dates.

HotelStayAxel ratePublic rateSavingCheck current rates
Residence Inn by Marriott Birmingham Downtown at UAB · 3-star, Residence InnNov 20 to Nov 22, 2026 · 2 nights · 2 adults$135 a night · refundable$190 a night on Expedia$55 a night less (29%)Check current rates for these dates
Hilton Birmingham Downtown at UAB · 4-star, Hilton HotelsNov 20 to Nov 22, 2026 · 2 nights · 2 adults$169 a night · non-refundable$205 a night on Expedia$36 a night less (17%)Check current rates for these dates
Home2 Suites by Hilton Birmingham Downtown · 3-star, Home2 SuitesNov 13 to Nov 15, 2026 · 2 nights · 2 adults$183 a night · non-refundable$215 a night on Expedia$32 a night less (14%)Check current rates for these dates
Hotel Indigo Birmingham Five Points S - UAB by IHG · 4-star, Hotel IndigoNov 20 to Nov 22, 2026 · 2 nights · 2 adults$200 a night · non-refundable$231 a night on Expedia$31 a night less (13%)Check current rates for these dates
Hilton Garden Inn Downtown Birmingham · 3-star, Hilton Garden InnNov 20 to Nov 22, 2026 · 2 nights · 2 adults$175 a night · non-refundable$191 a night on Expedia$16 a night less (8%)Check current rates for these dates
Courtyard by Marriott Birmingham Downtown at UAB · 3-star, CourtyardNov 20 to Nov 22, 2026 · 2 nights · 2 adults$222 a night · refundable$235 a night on Expedia$13 a night less (5%)Check current rates for these dates
The Painted Lady · 2-starNov 29 to Nov 30, 2026 · 1 night · 1 adult$122 a night · refundablenot seenCheck current rates for these dates
Homewood Suites by Hilton Birmingham Downtown Near UAB · 3-star, Homewood SuitesNov 29 to Nov 30, 2026 · 1 night · 1 adult$127 a night · non-refundablenot seenCheck current rates for these dates
Homewood Birmingham Downtown Near UabNov 29 to Nov 30, 2026 · 1 night · 1 adult$130 a night · includes $3 a night paid at the hotel · non-refundablenot seenCheck current rates for these dates
SpringHill Suites Birmingham Downtown at UAB · 3-star, SpringHill SuitesNov 29 to Nov 30, 2026 · 1 night · 1 adult$174 a night · refundablenot seenCheck current rates for these dates
Springhill Suites By Marriott Birmingham Downtown At Uab · SpringHill SuitesNov 29 to Nov 30, 2026 · 1 night · 1 adult$491 a night · refundablenot seenCheck current rates for these dates
Barsala At Tower On Tenth · 4-starDec 11 to Dec 13, 2026 · 2 nights · 2 adults$262 a night · refundablenot seenCheck current rates for these dates

More of Birmingham, Alabama

Where to stay in Birmingham, Alabama: the 6 best neighborhoods, ranked

Hotels in Birmingham, Alabama with their own rate page

Each page lists every stay Axel priced for that hotel this week, beside the public rate for the same dates.

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  • This page: The best hotels in Five Points South & UAB, Birmingham, Alabama, ranked. 7 hotels in Five Points South & UAB, Birmingham, Alabama, ranked by Axel's take, with Axel's rate beside the public one. Five Points South & UAB is #2 of 6 places to stay in Birmingham, Alabama: Best for UAB visits and restaurant-led stays, with a changing nightlife scene.
  • Live prices: fetched on a traveler's behalf, this page links live rooms and rates in Five Points South & UAB for their dates. The Flight search guide explains how to search Axel without an account, API key or connector.
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6 hotels in Five Points South & UAB seen below the public rate in the last 7 days, typically 13% less than Expedia.

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#2 of 6 places to stay in Birmingham, Alabama

Axel's take on Five Points South & UAB

6.7/10

Best for UAB visits and restaurant-led stays, with a changing nightlife scene.

Getting around
8.4
On your doorstep
3.5
Hotels
6.3
Value
4.5
Axel’s verdict
8.0

Five Points South gathers around the Storyteller Fountain, 20th Street South and the surrounding historic streets. Independent restaurants and older buildings give it more neighborhood character than a highway interchange, while UAB brings a working university-and-hospital rhythm. Stay here when campus appointments or dinners matter more than convention access.

Be precise about your street: hospital-side blocks and the fountain’s restaurant pocket are not interchangeable. The nightlife has also changed, with established venues closing and new pubs and food businesses replacing some of them; older bar lists are unreliable. Skip it for uninterrupted quiet or if you expect the entire district to stay busy late.

Best for
food loverstravelers without a carLGBTQ+ travelersnightlife
Skip it if
You need reliably quiet surroundings; Your main destination is the BJCC
Getting around
Walk the restaurant pocket and nearby UAB blocks; Magic City Connector, MAX 14, 31 and 280 serve the area. From BHM, rideshare is simplest; MAX On-Demand reaches Central Station for onward transit.
After dark
Expect pub activity near the fountain, not an all-night district; LGBTQ nightlife at Al’s on Seventh is farther east along Seventh Avenue South.

Where to look in Five Points South & UAB

Compare all 6 neighborhoods in Birmingham, Alabama

The best hotels in Five Points South & UAB, ranked by Axel's take

Each hotel is scored for what it is by Axel's own review. The rate is one stay Axel priced this week, beside the public rate for the same dates. Typical Axel rate $218 a night · usually 7% under the public rate.

How to choose

What paying more buys

Residence Inn is cheaper than most here yet already provides spacious kitchen suites and breakfast. Paying more for Courtyard buys direct hospital skybridge access; much pricier SpringHill Suites adds an indoor pool but brings elevator and maintenance concerns. The extra spend is hard to justify unless that connection or indoor swimming specifically matters.

Typical rates with Axel here run from $152 a night at Residence Inn by Marriott Birmingham Downtown at UAB to $510 at Springhill Suites By Marriott Birmingham Downtown At Uab (last 30 days).

  1. Residence Inn by Marriott Birmingham Downtown at UAB
    #1 in Five Points South & UAB

    Residence Inn by Marriott Birmingham Downtown at UAB

    A practical 3-star, all-suite extended-stay hotel beside UAB

    8.5/10

    A strong UAB base with roomy suites and genuinely helpful staff

    Why it's here:
    cheaper-than-most full-kitchen suites with generous space, included breakfast and particularly helpful staff
    Accept:
    paid sloping parking, alternate-day housekeeping and a seasonal pool
    • UAB patients and visiting families
    • Extended-stay business travelers
    • Families wanting a kitchen
    Axel
    $127 /night
    Expedia
    $178 /night
    $51/night less than Expedia (29%)

    Rate for Dec 8 to Dec 10, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review
  2. Hilton Garden Inn Downtown Birmingham
    #2 in Five Points South & UAB

    Hilton Garden Inn Downtown Birmingham

    a practical 3-star downtown hotel near UAB and Railroad Park

    8.4/10

    A strong downtown base with friendly staff, comfortable rooms and paid extras.

    Why it's here:
    comfortable, spacious rooms near UAB and Railroad Park, with an on-site restaurant and bar
    Accept:
    breakfast and self-parking cost extra
    • UAB and hospital visitors
    • baseball and theater trips
    • downtown business stays
    Axel
    $175 /night
    Expedia
    $191 /night
    $16/night less than Expedia (8%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review
  3. Courtyard by Marriott Birmingham Downtown at UAB
    #3 in Five Points South & UAB

    Courtyard by Marriott Birmingham Downtown at UAB

    a practical 3-star hotel connected to UAB Hospital

    8.3/10

    A strong choice for UAB visits, with comfortable rooms but awkward parking.

    Why it's here:
    direct hospital skybridge access with comfortable, good-sized rooms and welcoming staff
    Accept:
    paid off-site parking, extra breakfast and alternate-day housekeeping
    • UAB patients and visiting families
    • university and medical business
    • travelers prioritizing hospital access
    Axel
    $222 /night
    Expedia
    $235 /night
    $13/night less than Expedia (5%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review
  4. Hilton Birmingham Downtown at UAB
    #4 in Five Points South & UAB

    Hilton Birmingham Downtown at UAB

    a renovated, full-service 4-star in UAB’s medical district

    8.1/10

    A practical UAB base with refreshed rooms and helpful staff, but some uneven execution.

    Why it's here:
    refreshed UAB rooms with complimentary airport and hospital shuttles
    Accept:
    parking and breakfast charges; uneven housekeeping and problem follow-through
    • UAB patients and visiting families
    • University visitors
    • Business and conference travelers
    Axel
    $169 /night
    Expedia
    $205 /night
    $36/night less than Expedia (17%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review
  5. Home2 Suites by Hilton Birmingham Downtown
    #5 in Five Points South & UAB

    Home2 Suites by Hilton Birmingham Downtown

    a practical 3-star extended-stay hotel near UAB

    8.0/10

    A useful downtown base with roomy suites, friendly staff and some housekeeping inconsistencies.

    Why it's here:
    roomy kitchenette suites near Railroad Park, with breakfast included
    Accept:
    paid parking and uneven bathroom, upholstery and room upkeep
    • UAB and hospital visitors
    • families wanting kitchenettes
    • longer downtown stays
    Axel
    $183 /night
    Expedia
    $215 /night
    $32/night less than Expedia (14%)

    Rate for Nov 13 to Nov 15, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review
  6. Springhill Suites By Marriott Birmingham Downtown At Uab
    #6 in Five Points South & UAB

    Springhill Suites By Marriott Birmingham Downtown At Uab

    a practical 3-star Marriott all-suite hotel near UAB Hospital

    7.7/10

    A useful UAB base with roomy suites, but maintenance needs more consistency.

    Why it's here:
    roomy suites near UAB Hospital with included breakfast and an indoor pool
    Accept:
    a steep premium despite elevator problems, worn furnishings and paid parking
    • UAB hospital visitors
    • Short business stays
    • Families wanting extra room
    Axel
    $418 /night
    Per night, all in, as a free account pays it

    Rate for Nov 20 to Nov 25, 2026 · 5 nights · 1 adult · Seen Oct 20

    Check current rates for these datesAll rates and Axel's full review
  7. Hotel Indigo Birmingham Five Points S - UAB by IHG
    #7 in Five Points South & UAB

    Hotel Indigo Birmingham Five Points S - UAB by IHG

    a historic 4-star boutique hotel in Five Points South

    6.8/10

    Historic character and a lively location, but upkeep falls short of four-star expectations.

    Why it's here:
    historic character beside Five Points dining and nightlife
    Accept:
    nightlife noise, uneven housekeeping and maintenance, plus parking charges
    • nightlife-focused weekend visitors
    • UAB visitors who prioritize nearby dining
    • travelers who enjoy historic buildings
    Axel
    $149 /night
    Expedia
    $172 /night
    $23/night less than Expedia (13%)

    Rate for Dec 8 to Dec 10, 2026 · 2 nights · 2 adults · Seen Oct 21

    Check current rates for these datesAll rates and Axel's full review

More deals seen in Five Points South & UAB this week

  • Residence Inn by Marriott Birmingham Downtown at UAB

    Residence Inn by Marriott Birmingham Downtown at UAB

    ★★★
    Axel
    $135 /night
    Expedia
    $190 /night
    $55/night less than Expedia (29%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • Hilton Birmingham Downtown at UAB

    Hilton Birmingham Downtown at UAB

    ★★★★
    Axel
    $169 /night
    Expedia
    $205 /night
    $36/night less than Expedia (17%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • Home2 Suites by Hilton Birmingham Downtown

    Home2 Suites by Hilton Birmingham Downtown

    ★★★
    Axel
    $183 /night
    Expedia
    $215 /night
    $32/night less than Expedia (14%)

    Rate for Nov 13 to Nov 15, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • Hotel Indigo Birmingham Five Points S - UAB by IHG

    Hotel Indigo Birmingham Five Points S - UAB by IHG

    ★★★★
    Axel
    $200 /night
    Expedia
    $231 /night
    $31/night less than Expedia (13%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • Hilton Garden Inn Downtown Birmingham

    Hilton Garden Inn Downtown Birmingham

    ★★★
    Axel
    $175 /night
    Expedia
    $191 /night
    $16/night less than Expedia (8%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • Courtyard by Marriott Birmingham Downtown at UAB

    Courtyard by Marriott Birmingham Downtown at UAB

    ★★★
    Axel
    $222 /night
    Expedia
    $235 /night
    $13/night less than Expedia (5%)

    Rate for Nov 20 to Nov 22, 2026 · 2 nights · 2 adults · Seen Oct 21

    See rooms for your dates
  • The Painted Lady

    The Painted Lady

    ★★
    Axel
    $122 /night
    Per night, all in, as a free account pays it

    Rate for Nov 29 to Nov 30, 2026 · 1 night · 1 adult · Seen Oct 22

    Check current rates for these dates
  • Homewood Suites by Hilton Birmingham Downtown Near UAB

    Homewood Suites by Hilton Birmingham Downtown Near UAB

    ★★★
    Axel
    $127 /night
    Per night, all in, as a free account pays it

    Rate for Nov 29 to Nov 30, 2026 · 1 night · 1 adult · Seen Oct 22

    Check current rates for these dates
  • Homewood Birmingham Downtown Near Uab

    Homewood Birmingham Downtown Near Uab

    Axel
    $130 /night

    Includes $3/night paid to the hotel at check-in

    Per night, all in, as a free account pays it

    Rate for Nov 29 to Nov 30, 2026 · 1 night · 1 adult · Seen Oct 22

    Check current rates for these dates

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