Flights from Saint Louis to Eastern Europe in December: flights from $589 one way, Nov 2026–Sep 2027

Flights for the months ahead

Lowest published fares for the months ahead: $865 round trip, Axel-exclusive, Air Canada / Austrian Airlines, 2 stops, Jan 9–16, 2027; $589 one way, Axel-exclusive, Air Canada, 2 stops, Jan 5, 2027; 144 priced flights on 72 exact dates, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

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Saint Louis (STL) to Prague (PRG): November 2026

Saint Louis (STL) to Prague (PRG): December 2026

Saint Louis (STL) to Prague (PRG): January 2027

Saint Louis (STL) to Prague (PRG): February 2027

Saint Louis (STL) to Prague (PRG): March 2027

Saint Louis (STL) to Prague (PRG): April 2027

Saint Louis (STL) to Prague (PRG): May 2027

Saint Louis (STL) to Prague (PRG): June 2027

Saint Louis (STL) to Prague (PRG): July 2027

Saint Louis (STL) to Prague (PRG): August 2027

Saint Louis (STL) to Prague (PRG): September 2027

Hotels in Prague for these trips

Hotels: under a trip, hotels in Prague for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Prague for these nights (Nov 19–22, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $234 total · 4★ Mama Shelter Prague, $255 total · 5★ Hotel Hoffmeister, $431 total
• Hotels in Prague for these nights (Nov 20–23, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $223 total · 4★ Mama Shelter Prague, $232 total · 5★ Hilton Prague Atrium, $389 total
• Hotels in Prague for these nights (Nov 21–28, 2026 · 7 nights · 2 adults, 1 room): 3★ Hotel OYA, $518 total · 4★ COLORFACTORY SPA Hotel, $772 total · 5★ Hotel Hoffmeister, $939 total
• Hotels in Prague for these nights (Nov 24–29, 2026 · 5 nights · 2 adults, 1 room): 3★ Hotel OYA, $463 total · 4★ COLORFACTORY SPA Hotel, $708 total · 5★ Hotel Hoffmeister, $871 total
• Hotels in Prague for these nights (Nov 26–29, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $331 total · 4★ Mama Shelter Prague, $433 total · 5★ Grandior Hotel Prague, $681 total
• Hotels in Prague for these nights (Nov 27–30, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $326 total · 4★ Mama Shelter Prague, $380 total · 5★ Grandior Hotel Prague, $655 total
• Hotels in Prague for these nights (Nov 28 – Dec 5, 2026 · 7 nights · 2 adults, 1 room): 3★ Hotel OYA, $883 total · 4★ Mama Shelter Prague, $983 total · 5★ Grand Hotel Prague Towers, $1,652 total
• Hotels in Prague for these nights (Dec 3–6, 2026 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG, $491 total · 4★ Courtyard by Marriott Prague Airport, $665 total · 5★ Grand Hotel Prague Towers, $812 total
• Hotels in Prague for these nights (Dec 4–7, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $750 total · 4★ Courtyard by Marriott Prague Airport, $660 total · 5★ Grand Hotel Prague Towers, $799 total
• Hotels in Prague for these nights (Dec 5–12, 2026 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $1,003 total · 4★ Mama Shelter Prague, $1,181 total · 5★ Grandior Hotel Prague, $2,035 total
• Hotels in Prague for these nights (Dec 10–13, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $693 total · 4★ Mama Shelter Prague, $627 total · 5★ Hilton Prague Atrium, $829.50 total
• Hotels in Prague for these nights (Dec 11–14, 2026 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG, $609 total · 4★ Mama Shelter Prague, $504 total · 5★ Hilton Prague Atrium, $766.50 total
• Hotels in Prague for these nights (Dec 12–19, 2026 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG, $911 total · 4★ Mama Shelter Prague, $828 total · 5★ Hilton Prague Atrium, $1,430 total
• Hotels in Prague for these nights (Dec 17–20, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $378 total · 4★ Mama Shelter Prague, $471 total · 5★ Grand Hotel Prague Towers, $647 total
• Hotels in Prague for these nights (Dec 18–21, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $334 total · 4★ Mama Shelter Prague, $457 total · 5★ Grand Hotel Prague Towers, $647 total
• Hotels in Prague for these nights (Dec 19–26, 2026 · 7 nights · 2 adults, 1 room): 3★ Hotel OYA, $820 total · 4★ COLORFACTORY SPA Hotel, $952 total · 5★ Grand Hotel Prague Towers, $1,334 total
• Hotels in Prague for these nights (Dec 22–27, 2026 · 5 nights · 2 adults, 1 room): 3★ Hotel OYA, $633 total · 4★ Mama Shelter Prague, $722 total · 5★ Grandior Hotel Prague, $1,040 total
• Hotels in Prague for these nights (Dec 24–27, 2026 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG, $396 total · 4★ Mama Shelter Prague, $425 total · 5★ Grandior Hotel Prague, $730 total
• Hotels in Prague for these nights (Dec 25–28, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $381 total · 4★ Mama Shelter Prague, $491 total · 5★ Grand Hotel Prague Towers, $741 total
• Hotels in Prague for these nights (Dec 26 – Jan 2, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel OYA, $1,186.50 total · 4★ Orea Hotel Andel's, $1,653 total · 5★ Grand Hotel Prague Towers, $2,091 total
• Hotels in Prague for these nights (Dec 30 – Jan 2, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $601.50 total · 4★ OREA Hotel Angelo Praha, $866 total · 5★ Le Palais Art Hotel Prague, $1,044 total
• Hotels in Prague for these nights (Dec 31 – Jan 3, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $477.50 total · 4★ OREA Hotel Angelo Praha, $731 total · 5★ Le Palais Art Hotel Prague, $833 total
• Hotels in Prague for these nights (Jan 1–4, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel OYA, $336 total · 4★ Mama Shelter Prague, $354 total · 5★ Grandior Hotel Prague, $576 total
• Hotels in Prague for these nights (Jan 2–9, 2027 · 7 nights · 2 adults, 1 room): 3★ Anna Hotel, $475 total · 4★ Mama Shelter Prague, $493 total · 5★ Grandior Hotel Prague, $716 total
• Hotels in Prague for these nights (Jan 7–10, 2027 · 3 nights · 2 adults, 1 room): 3★ Bohem Prague Hotel, $185 total · 4★ COLORFACTORY SPA Hotel, $188 total · 5★ Grandior Hotel Prague, $258 total
• Hotels in Prague for these nights (Jan 8–11, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $179 total · 4★ COLORFACTORY SPA Hotel, $180 total · 5★ Grandior Hotel Prague, $242 total
• Hotels in Prague for these nights (Jan 9–16, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $329 total · 4★ COLORFACTORY SPA Hotel, $347 total · 5★ Grandior Hotel Prague, $499 total
• Hotels in Prague for these nights (Jan 14–17, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $159 total · 4★ COLORFACTORY SPA Hotel, $173 total · 5★ Grandior Hotel Prague, $235 total
• Hotels in Prague for these nights (Jan 15–18, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $157 total · 4★ COLORFACTORY SPA Hotel, $173 total · 5★ Grandior Hotel Prague, $236 total
• Hotels in Prague for these nights (Jan 16–23, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $320 total · 4★ COLORFACTORY SPA Hotel, $348 total · 5★ Grandior Hotel Prague, $501 total
• Hotels in Prague for these nights (Jan 21–24, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $157 total · 4★ COLORFACTORY SPA Hotel, $200 total · 5★ Hotel Hoffmeister, $235 total
• Hotels in Prague for these nights (Jan 22–25, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $156 total · 4★ COLORFACTORY SPA Hotel, $194 total · 5★ Hotel Hoffmeister, $234 total
• Hotels in Prague for these nights (Jan 23–30, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $326 total · 4★ COLORFACTORY SPA Hotel, $358 total · 5★ Grandior Hotel Prague, $500 total
• Hotels in Prague for these nights (Jan 28–31, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $165 total · 4★ COLORFACTORY SPA Hotel, $174 total · 5★ Grandior Hotel Prague, $234 total
• Hotels in Prague for these nights (Jan 29 – Feb 1, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $160 total · 4★ COLORFACTORY SPA Hotel, $170 total · 5★ Grandior Hotel Prague, $234 total
• Hotels in Prague for these nights (Jan 30 – Feb 6, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $335 total · 4★ COLORFACTORY SPA Hotel, $369 total · 5★ Grandior Hotel Prague, $511 total
• Hotels in Prague for these nights (Feb 4–7, 2027 · 3 nights · 2 adults, 1 room): 3★ Anna Hotel, $168 total · 4★ Mama Shelter Prague, $200 total · 5★ Grandior Hotel Prague, $236 total
• Hotels in Prague for these nights (Feb 5–8, 2027 · 3 nights · 2 adults, 1 room): 3★ Bohem Prague Hotel, $173 total · 4★ Mama Shelter Prague, $194 total · 5★ Grandior Hotel Prague, $235 total
• Hotels in Prague for these nights (Feb 6–13, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $361 total · 4★ COLORFACTORY SPA Hotel, $407 total · 5★ Grandior Hotel Prague, $515 total
• Hotels in Prague for these nights (Feb 12–15, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $169 total · 4★ Mama Shelter Prague, $199 total · 5★ Grandior Hotel Prague, $261 total
• Hotels in Prague for these nights (Feb 19–22, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $166 total · 4★ Mama Shelter Prague, $196 total · 5★ Grandior Hotel Prague, $243 total
• Hotels in Prague for these nights (Feb 20–27, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $352 total · 4★ COLORFACTORY SPA Hotel, $398 total · 5★ Grandior Hotel Prague, $549 total
• Hotels in Prague for these nights (Mar 19–22, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $182 total · 4★ Mama Shelter Prague, $219 total · 5★ Grandior Hotel Prague, $317 total
• Hotels in Prague for these nights (Mar 20–27, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $501 total · 4★ Mama Shelter Prague, $575 total · 5★ Grandior Hotel Prague, $945 total
• Hotels in Prague for these nights (Mar 25–29, 2027 · 4 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $422 total · 4★ Mama Shelter Prague, $498 total · 5★ Grandium Hotel Prague, $838 total
• Hotels in Prague for these nights (Apr 16–19, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $240 total · 4★ Mama Shelter Prague, $298 total · 5★ Grandior Hotel Prague, $427 total
• Hotels in Prague for these nights (Apr 17–24, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Golden City Garni, $530 total · 4★ COLORFACTORY SPA Hotel, $609 total · 5★ Grandior Hotel Prague, $1,029 total
• Hotels in Prague for these nights (May 14–17, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (May 15–22, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (May 28–31, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Jun 11–14, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Jun 12–19, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Jul 2–6, 2027 · 4 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Jul 9–12, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Jul 10–17, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Aug 6–9, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Aug 7–14, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Sep 3–6, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Sep 4–11, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Sep 24–27, 2027 · 3 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague
• Hotels in Prague for these nights (Sep 25 – Oct 2, 2027 · 7 nights · 2 adults, 1 room): 3★ Holiday Inn Prague Congress Centre by IHG · 4★ Hotel Residence Agnes · 5★ Aria Hotel Prague

All hotels in Prague

Route overview: Saint Louis to Prague (PRG) flight deals

2026-11-19 → 2026-11-22 · Axel-exclusive $961.45

• Air Canada AC8890 / AC880 / LX1486: STL 2026-11-19 16:05:00 → PRG 2026-11-20 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2026-11-19 16:05:00 → YYZ 2026-11-19 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2026-11-19 20:25:00 → ZRH 2026-11-20 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2026-11-20 12:35:00 → PRG 2026-11-20 13:55:00.
• Lufthansa LH1401 / LH448: PRG 2026-11-22 07:05:00 → STL 2026-11-22 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2026-11-22 07:05:00 → FRA 2026-11-22 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2026-11-22 10:45:00 → STL 2026-11-22 13:45:00.

2026-11-19 → 2026-11-22 · Axel-exclusive $981.05

• American Airlines AA5105 / EI114 / EI642: STL 2026-11-19 12:19:00 → PRG 2026-11-20 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2026-11-19 12:19:00 → PHL 2026-11-19 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2026-11-19 17:40:00 → DUB 2026-11-20 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2026-11-20 07:25:00 → PRG 2026-11-20 11:00:00.
• Lufthansa LH1401 / LH448: PRG 2026-11-22 07:05:00 → STL 2026-11-22 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2026-11-22 07:05:00 → FRA 2026-11-22 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2026-11-22 10:45:00 → STL 2026-11-22 13:45:00.

2026-11-24 · one way · Axel-exclusive $651.00

• Air Canada AC8890 / AC880 / LX1486: STL 2026-11-24 16:05:00 → PRG 2026-11-25 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2026-11-24 16:05:00 → YYZ 2026-11-24 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2026-11-24 20:25:00 → ZRH 2026-11-25 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2026-11-25 12:35:00 → PRG 2026-11-25 13:55:00.

2026-11-24 · one way · Axel-exclusive $682.50

• American Airlines AA5105 / EI114 / EI642: STL 2026-11-24 12:19:00 → PRG 2026-11-25 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2026-11-24 12:19:00 → PHL 2026-11-24 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2026-11-24 17:40:00 → DUB 2026-11-25 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2026-11-25 07:25:00 → PRG 2026-11-25 11:00:00.

2026-11-28 → 2026-12-05 · Axel-exclusive $932.00

• Air Canada AC8890 / AC880 / LX1486: STL 2026-11-28 16:05:00 → PRG 2026-11-29 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2026-11-28 16:05:00 → YYZ 2026-11-28 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2026-11-28 20:25:00 → ZRH 2026-11-29 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2026-11-29 12:35:00 → PRG 2026-11-29 13:55:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2026-12-05 07:25:00 → STL 2026-12-05 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2026-12-05 07:25:00 → VIE 2026-12-05 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2026-12-05 10:40:00 → EWR 2026-12-05 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2026-12-05 21:14:00 → STL 2026-12-05 23:05:00.

2026-11-28 → 2026-12-05 · Axel-exclusive $953.00

• American Airlines AA5105 / EI114 / EI642: STL 2026-11-28 12:19:00 → PRG 2026-11-29 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2026-11-28 12:19:00 → PHL 2026-11-28 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2026-11-28 17:40:00 → DUB 2026-11-29 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2026-11-29 07:25:00 → PRG 2026-11-29 11:00:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2026-12-05 07:25:00 → STL 2026-12-05 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2026-12-05 07:25:00 → VIE 2026-12-05 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2026-12-05 10:40:00 → EWR 2026-12-05 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2026-12-05 21:14:00 → STL 2026-12-05 23:05:00.

2026-12-12 → 2026-12-19 · Axel-exclusive $1027.50

• Air Canada AC8890 / AC880 / LX1486: STL 2026-12-12 16:05:00 → PRG 2026-12-13 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2026-12-12 16:05:00 → YYZ 2026-12-12 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2026-12-12 20:25:00 → ZRH 2026-12-13 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2026-12-13 12:35:00 → PRG 2026-12-13 13:55:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2026-12-19 07:25:00 → STL 2026-12-19 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2026-12-19 07:25:00 → VIE 2026-12-19 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2026-12-19 10:40:00 → EWR 2026-12-19 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2026-12-19 21:14:00 → STL 2026-12-19 23:05:00.

2026-12-12 → 2026-12-19 · Axel-exclusive $1047.50

• American Airlines AA5105 / EI114 / EI642: STL 2026-12-12 12:19:00 → PRG 2026-12-13 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2026-12-12 12:19:00 → PHL 2026-12-12 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2026-12-12 17:40:00 → DUB 2026-12-13 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2026-12-13 07:25:00 → PRG 2026-12-13 11:00:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2026-12-19 07:25:00 → STL 2026-12-19 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2026-12-19 07:25:00 → VIE 2026-12-19 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2026-12-19 10:40:00 → EWR 2026-12-19 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2026-12-19 21:14:00 → STL 2026-12-19 23:05:00.

2026-12-25 → 2026-12-28 · Axel-exclusive $1181.25

• Air Canada AC8890 / AC880 / LX1486: STL 2026-12-25 16:05:00 → PRG 2026-12-26 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2026-12-25 16:05:00 → YYZ 2026-12-25 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2026-12-25 20:25:00 → ZRH 2026-12-26 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2026-12-26 12:35:00 → PRG 2026-12-26 13:55:00.
• Lufthansa LH1401 / LH448: PRG 2026-12-28 07:05:00 → STL 2026-12-28 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2026-12-28 07:05:00 → FRA 2026-12-28 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2026-12-28 10:45:00 → STL 2026-12-28 13:45:00.

2026-12-25 → 2026-12-28 · Axel-exclusive $1206.25

• American Airlines AA5105 / EI114 / EI642: STL 2026-12-25 12:19:00 → PRG 2026-12-26 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2026-12-25 12:19:00 → PHL 2026-12-25 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2026-12-25 17:40:00 → DUB 2026-12-26 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2026-12-26 07:25:00 → PRG 2026-12-26 11:00:00.
• Lufthansa LH1401 / LH448: PRG 2026-12-28 07:05:00 → STL 2026-12-28 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2026-12-28 07:05:00 → FRA 2026-12-28 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2026-12-28 10:45:00 → STL 2026-12-28 13:45:00.

2027-01-07 → 2027-01-10 · Axel-exclusive $897.75

• Air Canada AC8890 / AC880 / LX1486: STL 2027-01-07 16:05:00 → PRG 2027-01-08 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-01-07 16:05:00 → YYZ 2027-01-07 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-01-07 20:25:00 → ZRH 2027-01-08 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-01-08 12:35:00 → PRG 2027-01-08 13:55:00.
• Lufthansa LH1401 / LH448: PRG 2027-01-10 07:05:00 → STL 2027-01-10 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-01-10 07:05:00 → FRA 2027-01-10 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-01-10 10:45:00 → STL 2027-01-10 13:45:00.

2027-01-07 → 2027-01-10 · Axel-exclusive $916.75

• American Airlines AA5105 / EI114 / EI642: STL 2027-01-07 12:19:00 → PRG 2027-01-08 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-01-07 12:19:00 → PHL 2027-01-07 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-01-07 17:40:00 → DUB 2027-01-08 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-01-08 07:25:00 → PRG 2027-01-08 11:00:00.
• Lufthansa LH1401 / LH448: PRG 2027-01-10 07:05:00 → STL 2027-01-10 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-01-10 07:05:00 → FRA 2027-01-10 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-01-10 10:45:00 → STL 2027-01-10 13:45:00.

2027-01-21 → 2027-01-24 · Axel-exclusive $897.75

• Air Canada AC8890 / AC880 / LX1486: STL 2027-01-21 16:05:00 → PRG 2027-01-22 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-01-21 16:05:00 → YYZ 2027-01-21 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-01-21 20:25:00 → ZRH 2027-01-22 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-01-22 12:35:00 → PRG 2027-01-22 13:55:00.
• Lufthansa LH1401 / LH448: PRG 2027-01-24 07:05:00 → STL 2027-01-24 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-01-24 07:05:00 → FRA 2027-01-24 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-01-24 10:45:00 → STL 2027-01-24 13:45:00.

2027-01-21 → 2027-01-24 · Axel-exclusive $931.00

• United Airlines UA4714 / UA953 / LH1690: STL 2027-01-21 15:00:00 → PRG 2027-01-22 13:05:00; 2 stop(s) via ORD, MUC; 905 minutes. Local airport times.
  • UA4714: STL 2027-01-21 15:00:00 → ORD 2027-01-21 16:42:00; layover at ORD: 78 minutes.
  • UA953: ORD 2027-01-21 18:00:00 → MUC 2027-01-22 09:35:00; layover at MUC: 160 minutes.
  • LH1690: MUC 2027-01-22 12:15:00 → PRG 2027-01-22 13:05:00.
• Lufthansa LH1401 / LH448: PRG 2027-01-24 07:05:00 → STL 2027-01-24 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-01-24 07:05:00 → FRA 2027-01-24 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-01-24 10:45:00 → STL 2027-01-24 13:45:00.

2027-02-04 → 2027-02-07 · Axel-exclusive $897.75

• Air Canada AC8890 / AC880 / LX1486: STL 2027-02-04 16:05:00 → PRG 2027-02-05 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-02-04 16:05:00 → YYZ 2027-02-04 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-02-04 20:25:00 → ZRH 2027-02-05 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-02-05 12:35:00 → PRG 2027-02-05 13:55:00.
• Lufthansa LH1401 / LH448: PRG 2027-02-07 07:05:00 → STL 2027-02-07 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-02-07 07:05:00 → FRA 2027-02-07 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-02-07 10:45:00 → STL 2027-02-07 13:45:00.

2027-02-04 → 2027-02-07 · Axel-exclusive $916.75

• American Airlines AA5105 / EI114 / EI642: STL 2027-02-04 12:19:00 → PRG 2027-02-05 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-02-04 12:19:00 → PHL 2027-02-04 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-02-04 17:40:00 → DUB 2027-02-05 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-02-05 07:25:00 → PRG 2027-02-05 11:00:00.
• Lufthansa LH1401 / LH448: PRG 2027-02-07 07:05:00 → STL 2027-02-07 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-02-07 07:05:00 → FRA 2027-02-07 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-02-07 10:45:00 → STL 2027-02-07 13:45:00.

2027-03-19 → 2027-03-22 · Axel-exclusive $945.00

• Air Canada AC8890 / AC880 / LX1486: STL 2027-03-19 16:05:00 → PRG 2027-03-20 12:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-03-19 16:05:00 → YYZ 2027-03-19 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-03-19 20:25:00 → ZRH 2027-03-20 09:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-03-20 11:35:00 → PRG 2027-03-20 12:55:00.
• Lufthansa LH1401 / LH448: PRG 2027-03-22 07:05:00 → STL 2027-03-22 14:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-03-22 07:05:00 → FRA 2027-03-22 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-03-22 10:45:00 → STL 2027-03-22 14:45:00.

2027-03-19 → 2027-03-22 · Axel-exclusive $965.00

• American Airlines AA5105 / EI114 / EI642: STL 2027-03-19 12:19:00 → PRG 2027-03-20 10:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-03-19 12:19:00 → PHL 2027-03-19 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-03-19 17:40:00 → DUB 2027-03-20 04:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-03-20 06:25:00 → PRG 2027-03-20 10:00:00.
• Lufthansa LH1401 / LH448: PRG 2027-03-22 07:05:00 → STL 2027-03-22 14:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
  • LH1401: PRG 2027-03-22 07:05:00 → FRA 2027-03-22 08:15:00; layover at FRA: 150 minutes.
  • LH448: FRA 2027-03-22 10:45:00 → STL 2027-03-22 14:45:00.

2027-05-15 → 2027-05-22 · Axel-exclusive $1240.00

• Air Canada AC8890 / AC880 / LX1486: STL 2027-05-15 16:05:00 → PRG 2027-05-16 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-05-15 16:05:00 → YYZ 2027-05-15 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-05-15 20:25:00 → ZRH 2027-05-16 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-05-16 12:35:00 → PRG 2027-05-16 13:55:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-05-22 07:25:00 → STL 2027-05-22 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-05-22 07:25:00 → VIE 2027-05-22 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-05-22 10:40:00 → EWR 2027-05-22 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-05-22 21:14:00 → STL 2027-05-22 23:05:00.

2027-05-15 → 2027-05-22 · Axel-exclusive $1265.00

• American Airlines AA5105 / EI114 / EI642: STL 2027-05-15 12:19:00 → PRG 2027-05-16 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-05-15 12:19:00 → PHL 2027-05-15 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-05-15 17:40:00 → DUB 2027-05-16 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-05-16 07:25:00 → PRG 2027-05-16 11:00:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-05-22 07:25:00 → STL 2027-05-22 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-05-22 07:25:00 → VIE 2027-05-22 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-05-22 10:40:00 → EWR 2027-05-22 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-05-22 21:14:00 → STL 2027-05-22 23:05:00.

2027-07-10 → 2027-07-17 · Axel-exclusive $1240.00

• Air Canada AC8890 / AC880 / LX1486: STL 2027-07-10 16:05:00 → PRG 2027-07-11 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-07-10 16:05:00 → YYZ 2027-07-10 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-07-10 20:25:00 → ZRH 2027-07-11 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-07-11 12:35:00 → PRG 2027-07-11 13:55:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-07-17 07:25:00 → STL 2027-07-17 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-07-17 07:25:00 → VIE 2027-07-17 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-07-17 10:40:00 → EWR 2027-07-17 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-07-17 21:14:00 → STL 2027-07-17 23:05:00.

2027-07-10 → 2027-07-17 · Axel-exclusive $1265.00

• American Airlines AA5105 / EI114 / EI642: STL 2027-07-10 12:19:00 → PRG 2027-07-11 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-07-10 12:19:00 → PHL 2027-07-10 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-07-10 17:40:00 → DUB 2027-07-11 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-07-11 07:25:00 → PRG 2027-07-11 11:00:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-07-17 07:25:00 → STL 2027-07-17 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-07-17 07:25:00 → VIE 2027-07-17 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-07-17 10:40:00 → EWR 2027-07-17 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-07-17 21:14:00 → STL 2027-07-17 23:05:00.

2027-09-25 → 2027-10-02 · Axel-exclusive $1240.00

• Air Canada AC8890 / AC880 / LX1486: STL 2027-09-25 16:05:00 → PRG 2027-09-26 13:55:00; 2 stop(s) via YYZ, ZRH; 890 minutes. Local airport times.
  • AC8890: STL 2027-09-25 16:05:00 → YYZ 2027-09-25 19:05:00; layover at YYZ: 80 minutes.
  • AC880: YYZ 2027-09-25 20:25:00 → ZRH 2027-09-26 10:25:00; layover at ZRH: 130 minutes.
  • LX1486: ZRH 2027-09-26 12:35:00 → PRG 2027-09-26 13:55:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-10-02 07:25:00 → STL 2027-10-02 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-10-02 07:25:00 → VIE 2027-10-02 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-10-02 10:40:00 → EWR 2027-10-02 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-10-02 21:14:00 → STL 2027-10-02 23:05:00.

2027-09-25 → 2027-10-02 · Axel-exclusive $1265.00

• American Airlines AA5105 / EI114 / EI642: STL 2027-09-25 12:19:00 → PRG 2027-09-26 11:00:00; 2 stop(s) via PHL, DUB; 941 minutes. Local airport times.
  • AA5105: STL 2027-09-25 12:19:00 → PHL 2027-09-25 15:32:00; layover at PHL: 128 minutes.
  • EI114: PHL 2027-09-25 17:40:00 → DUB 2027-09-26 05:15:00; layover at DUB: 130 minutes.
  • EI642: DUB 2027-09-26 07:25:00 → PRG 2027-09-26 11:00:00.
• Austrian Airlines OS650 / OS37 / UA2799: PRG 2027-10-02 07:25:00 → STL 2027-10-02 23:05:00; 2 stop(s) via VIE, EWR; 1360 minutes. Local airport times.
  • OS650: PRG 2027-10-02 07:25:00 → VIE 2027-10-02 08:20:00; layover at VIE: 140 minutes.
  • OS37: VIE 2027-10-02 10:40:00 → EWR 2027-10-02 14:15:00; layover at EWR: 419 minutes.
  • UA2799: EWR 2027-10-02 21:14:00 → STL 2027-10-02 23:05:00.

More dates for this route

• Nov 19, 2026 · Return options
• Nov 27, 2026 · Return options
• Dec 8, 2026 · Return options
• Dec 19, 2026 · Return options
• Dec 29, 2026 · Return options
• Jan 8, 2027 · Return options
• Jan 19, 2027 · Return options
• Jan 30, 2027 · Return options
• Feb 19, 2027 · Return options
• May 14, 2027 · Return options
• Jul 9, 2027 · Return options
• Sep 25, 2027 · Return options
• Hotels in Prague with Axel

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• Colombia: in winter · in spring · for a week · for 10 days
• The Middle East: in winter · for a week · for 10 days
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• Canada: in summer · in winter · in fall · for 3 days · for 4 days · for a week
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• Alaska: in summer · in June · in July · in August · for 5 days · for a week · for 10 days
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• Utah: in winter · for Presidents' Day weekend · for MLK weekend · in spring · in summer · for 4 days · for a week
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• Colorado: in summer · in winter · for Presidents' Day weekend · for MLK weekend · for spring break · for 4 days · for a week
• Montana and Wyoming: in summer · in winter · for a week · for 10 days
• Texas: in spring · in fall · for 3 days · for 4 days
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Eastern Europe in December from other cities

Fares observed November 2 – 6, 2026. USD for the travelers shown.

The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.

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Hotels in Prague with Axel

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Where to stay: Where to stay in Prague: the 9 best neighborhoods, ranked · Prague hotels where a family of four can share one room

Hotel details in Prague: Hotel Residence Agnes 4★ · MOOo by the Castle 4★ · Hotel CUBE Prague 3★ · Anna Hotel 3★ · The Viaduct Suites & More 4★ from $94 a night in the next 30 days · All 378 hotels in Prague

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• This page: Flights from Saint Louis to Eastern Europe in December. Round-trip fares from Saint Louis to Eastern Europe in December: Prague, Vienna, Budapest, Krakow, Warsaw and Berlin and more. Saved fares for trips within December, with the cheapest for each destination and a link to search your own dates.
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