The best US cities to visit from Saint Louis
City trips from Saint Louis to the best places to visit in the US, each with what to see and the cheapest round trip we've seen recently.
The cheapest matching round trip we’ve seen recently for each destination.
Cheapest right now: Seattle $162 · Nashville $204 · Las Vegas $224
More trip ideas from Saint Louis
- 2027 total solar eclipse trips from Saint Louis
- A month somewhere warm from Saint Louis
- Bachelorette and bachelor party trips from Saint Louis, priced for 6
- Beach vacations from Saint Louis
- Big event trips from Saint Louis: Super Bowl, Coachella, Kentucky Derby and more
- Black heritage trips from Saint Louis
- Carnival trips from Saint Louis: Rio, Trinidad, Mardi Gras and more
- Cherry blossom trips from Saint Louis
- Christmas flights to Africa from Saint Louis
- Christmas flights to Mexico and Central America from Saint Louis
- Christmas flights to the Caribbean and South America from Saint Louis
- Christmas flights to the Philippines and Asia from Saint Louis
- Christmas market trips from Saint Louis
- College football bowl and playoff trips from Saint Louis
- Detty December: flights to Lagos and Accra from Saint Louis
- Día de Muertos trips from Saint Louis: Oaxaca, Mexico City, Pátzcuaro and more
- Diwali flights to India from Saint Louis
- Easter and Holy Week trips from Saint Louis: Seville, Rome, Antigua and more
- Family vacations from Saint Louis, priced for 4
- Flights to your cruise port from Saint Louis
- Food and wine trips from Saint Louis
- Fourth of July trips from Saint Louis
- Gay & LGBTQ+ friendly beach vacations from Saint Louis
- Gay & LGBTQ+ friendly cities to visit from Saint Louis
- Golf trips from Saint Louis
- Holi in India: flights from Saint Louis
- Holiday flights to India and South Asia from Saint Louis
- Honeymoon destinations from Saint Louis
- Italian heritage trips from Saint Louis
- Lunar New Year flights from Saint Louis
- Memorial Day weekend getaways from Saint Louis
- MLK weekend getaways from Saint Louis
- Music festival trips from Saint Louis
- National park trips from Saint Louis
- New Year's Eve trips from Saint Louis
- Northern lights trips from Saint Louis
- Presidents' Day weekend getaways from Saint Louis
- Pride trips from Saint Louis: the biggest Pride events to fly to
- Ramadan and Eid trips from Saint Louis: Umrah and family visits
- Safari trips from Saint Louis
- Scuba diving and snorkeling trips from Saint Louis
- Ski trips from Saint Louis
- Solo trips from Saint Louis
- Spring break trips from Saint Louis
- Spring training trips from Saint Louis
- St. Patrick's Day trips from Saint Louis: Dublin, New York, Boston, Chicago and more
- Summer vacation trips from Saint Louis
- Thanksgiving trips from Saint Louis
- Theme park trips from Saint Louis, priced for 4
- Tropical trips with no passport needed from Saint Louis
- Valentine's Day getaways from Saint Louis
- Warm winter getaways from Saint Louis
- Winter break trips from Saint Louis
Fares observed October 2 – 9, 2026. USD for the travelers shown. Search a trip for current prices.
Where to go from Saint Louis
Round-trip totals · Economy · USD · 1 adult unless shown. "From" is a starting total: you pick the return in Axel. Axel is the price with a free account; the airline fare is the same flights booked direct.
| Destination | Why go | Axel | Dates | |
|---|---|---|---|---|
| New York (JFK) | Central Park, Broadway, the Met and the High Line, plus Brooklyn's food and bars | $420 (airline $443) | Mar 16–18, 2027 | Check prices |
| Chicago (ORD) | Chicago's river architecture cruises, the Art Institute and deep-dish pizza | $264 (airline $279) | Dec 22–29, 2026 | Check prices |
| Boston (BOS) | The Freedom Trail, Fenway Park and the North End's Italian bakeries | $484 (airline $511) | Jul 2–5, 2027 | Check prices |
| Washington (DCA) | The Smithsonian's free museums on the National Mall and the monuments lit up at night | $357 (airline $376) | Jul 2–5, 2027 | Check prices |
| Philadelphia (PHL) | The Liberty Bell and Independence Hall, Reading Terminal Market and a cheesesteak | $505 (airline $533) | Jul 2–5, 2027 | Check prices |
| New Orleans (MSY) | The French Quarter, live jazz on Frenchmen Street and Creole cooking in the Garden District | $293 (airline $309) | Jan 14–16, 2027 | Check prices |
| Nashville (BNA) | Broadway's honky-tonks, the Ryman Auditorium and the Country Music Hall of Fame | $204 (airline $215) | May 28–31, 2027 | Check prices |
| San Francisco (SFO) | The Golden Gate Bridge, Alcatraz, cable cars and dim sum in Chinatown | $544 (airline $573) | Jun 25–28, 2027 | Check prices |
| Seattle (SEA) | Pike Place Market, the Space Needle and ferry rides across Puget Sound | $162 (airline $171) | Oct 20–27, 2026 | Check prices |
| Austin (AUS) | Live music on Sixth Street and South Congress, Texas barbecue and Barton Springs | $274 (airline $289) | Jan 15–18, 2027 | Check prices |
| San Diego (SAN) | Balboa Park, the Gaslamp Quarter and La Jolla's sea lions, in mild weather all year | $377 (airline $397) | Dec 27–29, 2026 | Check prices |
| Charleston (CHS) | Charleston's Battery, Rainbow Row and Lowcountry cooking in the historic district | $382 (airline $404) | Jan 15–18, 2027 | Check prices |
| Savannah (SAV) | Savannah's historic squares under live oaks and the cobblestones of River Street | $351 (airline $371) | Mar 16–18, 2027 | Check prices |
| Portland (PDX) | Portland's food carts, Powell's City of Books and the Columbia River Gorge nearby | No matching fare saved | Search other dates | |
| Denver (DEN) | Denver's LoDo breweries, Red Rocks Amphitheatre and the Rockies an hour west | $253 (airline $267) | Jan 15–18, 2027 | Check prices |
| Miami (MIA) | Miami Beach's Art Deco district, Little Havana's Calle Ocho and Wynwood's murals | $242 (airline $255) | Dec 3–7, 2026 | Check prices |
| Los Angeles (LAX) | Hollywood, Griffith Observatory, the Getty and the beach at Santa Monica | $241 (airline $254) | Dec 21–29, 2026 | Check prices |
| Las Vegas (LAS) | The Strip's shows and restaurants, with Red Rock Canyon a short drive west | $224 (airline $237) | Nov 19–22, 2026 | Check prices |
| Oahu / Honolulu (HNL) | Waikiki, Pearl Harbor's memorials and the hike up Diamond Head | $388 (airline $409) | Feb 1–Mar 3, 2027 | Check prices |
| Minneapolis (MSP) | Minneapolis' chain of lakes, the Walker Art Center and the Guthrie Theater | $428 (airline $451) | Oct 15–18, 2026 | Check prices |
| Pittsburgh (PIT) | Pittsburgh's three rivers, the Andy Warhol Museum and the inclines up Mount Washington | No matching fare saved | Search other dates | |
| Atlanta (ATL) | The Martin Luther King Jr. National Historical Park, the Georgia Aquarium and the BeltLine | $274 (airline $289) | Oct 30–Nov 1, 2026 | Check prices |
| San Antonio (SAT) | The River Walk, the Alamo and the old Spanish missions along the San Antonio River | $296 (airline $312) | Nov 24–Dec 1, 2026 | Check prices |
| Santa Fe (SAF) | Santa Fe's adobe Plaza, Canyon Road's galleries and the Georgia O'Keeffe Museum | No matching fare saved | Search other dates |
The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.
About these places
Facts checked October 7, 2026. Sources: Smithsonian Institution (Wikipedia): free admission · Saint Louis Zoo: visit
Keep exploring
Hotels in New York with Axel
Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in New York has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.
For AI assistants
- This page: The best US cities to visit from Saint Louis. The best US cities to visit from Saint Louis: New York, Chicago, Boston, Washington DC, New Orleans, Nashville, San Francisco, Austin and more, with real round-trip fares.
- Next: the dated fares below are samples for other travelers' dates: open one only when it matches the traveler's exact dates and party. Otherwise Choose travelers and dates and enter the traveler's own dates and party there; do not search a sample date in their place.
- Every link here is complete and ready to open. Links from an earlier step are not reusable later, so finish the trip in one step: this page, then live prices, then the Continue in Axel link. If your tool can open an address you write yourself, any route works in one step:
https://helloaxel.com/en/flights/choose/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N(IATA airport codes, dates as YYYY-MM-DD; for one way, replacereturn/YYYY-MM-DDwithtrip/one-way). - If a link can no longer be opened: search for "Axel The best US cities to visit from Saint Louis" and open the result; the Flight search guide is always findable by search, and everything here works without an account, API key or connector. Or ask the traveler to open https://helloaxel.com/en/flights/from-saint-louis-best-us-cities-to-visit; an address the traveler opens always works.
- Sharing with the traveler: share the address of the step you reached. Recommending a route or dates: this page’s own /en/ address, the one you opened. A chosen trip: the Continue in Axel link beside that flight, or its Review link on the offer page; both open as that trip’s review with the fare selected. Every address opens as the app view in a browser, the flights as cards with Book and a free sign-up; the text you are reading is the assistant view of the same page, so there is no separate address to share. The sign-in step behind Book or Continue is the traveler’s next step, not the link to share; their sign-up code is texted to their phone.