Best places to fly from Saint Louis for Memorial Day weekend
Memorial Day is the first summer weekend and busy by car more than by air: beaches and national parks fill from the road, cities are easy to reach and often cheaper than a normal weekend. Fares peak Thursday and Friday; Saturday departures are the quiet ones.
Nonstop from Saint Louis: Austin (Southwest · 2h 10m), Washington (Southwest, American · 2h), Denver (United, Southwest, Frontier · 2h 22m), San Diego (Southwest), Cancun (Frontier, Southwest, American), Las Vegas (Southwest, Frontier), San Jose Cabo (Southwest), Puerto Vallarta (Southwest), Punta Cana (Frontier, Southwest) and Montego Bay (Southwest), and 8 more. One stop via Atlanta: New York. No nonstop seen to Aruba and Nassau on the dates searched recently. No recent searches for Orlando, Honolulu and Miami.
Axel's pick: Austin, nonstop on Southwest and the lowest fare saved for these dates, $321.
Where to fly from Saint Louis for Memorial Day weekend: fares for Memorial Day weekend 2027 (May 28 to 31) to Cancun, Las Vegas, Orlando, Honolulu, San Jose Cabo and Puerto Vallarta and more, with the nonstops first. Pick a destination to see every date, or search your own dates in one tap.
AI assistants: For research, follow complete supplied links unchanged.
Saved round trips for Memorial Day weekend 2027 (May 28 – May 31, 2027).
Cheapest right now: Austin $321 · Washington $387 · Denver $413
Flights for your trip
Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.
| Exact travel dates | Airline | Flights | Total price | Price issued (UTC) |
|---|---|---|---|---|
| 2026-11-20 · one way | Frontier Airlines | F986 | $171.00 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | Southwest Airlines | WN1995 | $247.00 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Frontier Airlines | F986 / F987 | $339.63 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Southwest Airlines | WN1995 / WN1986 | $496.38 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | American Airlines | AA1992 + AA895 | $251.75 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | United Airlines | UA4439 + UA2371 | $261.25 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | Delta Air Lines | DL1102 + DL1939 | $266.00 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | American Airlines | AA1992 + AA895 / AA3310 | $518.70 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Delta Air Lines | DL1102 + DL1939 / DL595 + DL1403 | $527.73 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Frontier Airlines | F986 / F987 | $347.75 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Southwest Airlines | WN1995 / WN1996 | $496.38 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Southwest Airlines | WN1995 / WN1986 | $508.25 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Southwest Airlines | WN1995 / WN1996 | $508.25 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | Southwest Airlines | WN1679 + WN218 | $232.75 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | Southwest Airlines | WN3155 + WN305 | $232.75 | 2026-10-29T01:28:25Z |
| 2026-11-20 · one way | Southwest Airlines | WN4164 + WN144 | $232.75 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Frontier Airlines | F986 / F9152 + F94473 | $325.38 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Frontier Airlines | F986 / F9152 + F94473 | $335.25 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Southwest Airlines | WN1995 / WN390 + WN742 | $482.13 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Southwest Airlines | WN1679 + WN218 / WN1996 | $484.50 | 2026-10-29T01:28:25Z |
| 2026-11-20 → 2026-11-23 | Southwest Airlines | WN4164 + WN144 / WN1996 | $484.50 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Southwest Airlines | WN4164 + WN144 / WN1996 | $494.00 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Southwest Airlines | WN1679 + WN218 / WN1996 | $494.00 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Southwest Airlines | WN1995 / WN390 + WN742 | $495.75 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | American Airlines | AA1992 + AA895 / AA3310 | $528.60 | 2026-10-29T01:28:25Z |
| 2026-11-27 → 2026-12-04 | Delta Air Lines | DL1102 + DL1939 / DL595 + DL1403 | $540.35 | 2026-10-29T01:28:25Z |
2026-11-20 · one way · $171.00
- Frontier Airlines F986: STL 2026-11-20 06:05:00 → CUN 2026-11-20 10:19:00; nonstop; 194 minutes. Local airport times.
2026-11-20 · one way · $247.00
- Southwest Airlines WN1995: STL 2026-11-20 10:20:00 → CUN 2026-11-20 14:25:00; nonstop; 185 minutes. Local airport times.
2026-11-20 → 2026-11-23 · $339.63
- Frontier Airlines F986: STL 2026-11-20 06:05:00 → CUN 2026-11-20 10:19:00; nonstop; 194 minutes. Local airport times.
- Frontier Airlines F987: CUN 2026-11-23 14:15:00 → STL 2026-11-23 16:40:00; nonstop; 205 minutes. Local airport times.
2026-11-20 → 2026-11-23 · $496.38
- Southwest Airlines WN1995: STL 2026-11-20 13:15:00 → CUN 2026-11-20 17:20:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN1986: CUN 2026-11-23 12:00:00 → STL 2026-11-23 14:10:00; nonstop; 190 minutes. Local airport times.
2026-11-20 · one way · $251.75
- American Airlines AA1992 / AA895: STL 2026-11-20 05:00:00 → CUN 2026-11-20 12:29:00; 1 stop(s) via CLT; 389 minutes. Local airport times.
- AA1992: STL 2026-11-20 05:00:00 → CLT 2026-11-20 07:55:00; layover at CLT: 85 minutes.
- AA895: CLT 2026-11-20 09:20:00 → CUN 2026-11-20 12:29:00.
2026-11-20 · one way · $261.25
- United Airlines UA4439 / UA2371: STL 2026-11-20 05:25:00 → CUN 2026-11-20 13:43:00; 1 stop(s) via ORD; 438 minutes. Local airport times.
- UA4439: STL 2026-11-20 05:25:00 → ORD 2026-11-20 06:58:00; layover at ORD: 102 minutes.
- UA2371: ORD 2026-11-20 08:40:00 → CUN 2026-11-20 13:43:00.
2026-11-20 · one way · $266.00
- Delta Air Lines DL1102 / DL1939: STL 2026-11-20 14:31:00 → CUN 2026-11-20 21:08:00; 1 stop(s) via ATL; 337 minutes. Local airport times.
- DL1102: STL 2026-11-20 14:31:00 → ATL 2026-11-20 17:05:00; layover at ATL: 84 minutes.
- DL1939: ATL 2026-11-20 18:29:00 → CUN 2026-11-20 21:08:00.
2026-11-20 → 2026-11-23 · $518.70
- American Airlines AA1992 / AA895: STL 2026-11-20 05:00:00 → CUN 2026-11-20 12:29:00; 1 stop(s) via CLT; 389 minutes. Local airport times.
- AA1992: STL 2026-11-20 05:00:00 → CLT 2026-11-20 07:55:00; layover at CLT: 85 minutes.
- AA895: CLT 2026-11-20 09:20:00 → CUN 2026-11-20 12:29:00.
- American Airlines AA3310: CUN 2026-11-23 12:49:00 → STL 2026-11-23 15:21:00; nonstop; 212 minutes. Local airport times.
2026-11-20 → 2026-11-23 · $527.73
- Delta Air Lines DL1102 / DL1939: STL 2026-11-20 14:31:00 → CUN 2026-11-20 21:08:00; 1 stop(s) via ATL; 337 minutes. Local airport times.
- DL1102: STL 2026-11-20 14:31:00 → ATL 2026-11-20 17:05:00; layover at ATL: 84 minutes.
- DL1939: ATL 2026-11-20 18:29:00 → CUN 2026-11-20 21:08:00.
- Delta Air Lines DL595 / DL1403: CUN 2026-11-23 17:35:00 → STL 2026-11-23 23:26:00; 1 stop(s) via ATL; 411 minutes. Local airport times.
- DL595: CUN 2026-11-23 17:35:00 → ATL 2026-11-23 20:25:00; layover at ATL: 135 minutes.
- DL1403: ATL 2026-11-23 22:40:00 → STL 2026-11-23 23:26:00.
2026-11-27 → 2026-12-04 · $347.75
- Frontier Airlines F986: STL 2026-11-27 06:05:00 → CUN 2026-11-27 10:19:00; nonstop; 194 minutes. Local airport times.
- Frontier Airlines F987: CUN 2026-12-04 14:05:00 → STL 2026-12-04 16:25:00; nonstop; 200 minutes. Local airport times.
2026-11-20 → 2026-11-23 · $496.38
- Southwest Airlines WN1995: STL 2026-11-20 10:20:00 → CUN 2026-11-20 14:25:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN1996: CUN 2026-11-23 16:00:00 → STL 2026-11-23 18:10:00; nonstop; 190 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $508.25
- Southwest Airlines WN1995: STL 2026-11-27 13:15:00 → CUN 2026-11-27 17:20:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN1986: CUN 2026-12-04 12:00:00 → STL 2026-12-04 14:10:00; nonstop; 190 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $508.25
- Southwest Airlines WN1995: STL 2026-11-27 10:20:00 → CUN 2026-11-27 14:25:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN1996: CUN 2026-12-04 10:45:00 → STL 2026-12-04 12:45:00; nonstop; 180 minutes. Local airport times.
2026-11-20 · one way · $232.75
- Southwest Airlines WN1679 / WN218: STL 2026-11-20 13:05:00 → CUN 2026-11-20 20:25:00; 1 stop(s) via MDW; 380 minutes. Local airport times.
- WN1679: STL 2026-11-20 13:05:00 → MDW 2026-11-20 14:10:00; layover at MDW: 95 minutes.
- WN218: MDW 2026-11-20 15:45:00 → CUN 2026-11-20 20:25:00.
2026-11-20 · one way · $232.75
- Southwest Airlines WN3155 / WN305: STL 2026-11-20 11:45:00 → CUN 2026-11-20 19:45:00; 1 stop(s) via HOU; 420 minutes. Local airport times.
- WN3155: STL 2026-11-20 11:45:00 → HOU 2026-11-20 13:50:00; layover at HOU: 165 minutes.
- WN305: HOU 2026-11-20 16:35:00 → CUN 2026-11-20 19:45:00.
2026-11-20 · one way · $232.75
- Southwest Airlines WN4164 / WN144: STL 2026-11-20 08:00:00 → CUN 2026-11-20 15:00:00; 1 stop(s) via MCI; 360 minutes. Local airport times.
- WN4164: STL 2026-11-20 08:00:00 → MCI 2026-11-20 09:10:00; layover at MCI: 95 minutes.
- WN144: MCI 2026-11-20 10:45:00 → CUN 2026-11-20 15:00:00.
2026-11-20 → 2026-11-23 · $325.38
- Frontier Airlines F986: STL 2026-11-20 06:20:00 → CUN 2026-11-20 10:34:00; nonstop; 194 minutes. Local airport times.
- Frontier Airlines F9152 / F94473: CUN 2026-11-23 11:28:00 → STL 2026-11-23 17:42:00; 1 stop(s) via ATL; 434 minutes. Local airport times.
- F9152: CUN 2026-11-23 11:28:00 → ATL 2026-11-23 14:18:00; layover at ATL: 151 minutes.
- F94473: ATL 2026-11-23 16:49:00 → STL 2026-11-23 17:42:00.
2026-11-27 → 2026-12-04 · $335.25
- Frontier Airlines F986: STL 2026-11-27 06:20:00 → CUN 2026-11-27 10:34:00; nonstop; 194 minutes. Local airport times.
- Frontier Airlines F9152 / F94473: CUN 2026-12-04 11:28:00 → STL 2026-12-04 17:42:00; 1 stop(s) via ATL; 434 minutes. Local airport times.
- F9152: CUN 2026-12-04 11:28:00 → ATL 2026-12-04 14:18:00; layover at ATL: 151 minutes.
- F94473: ATL 2026-12-04 16:49:00 → STL 2026-12-04 17:42:00.
2026-11-20 → 2026-11-23 · $482.13
- Southwest Airlines WN1995: STL 2026-11-20 12:20:00 → CUN 2026-11-20 16:25:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN390 / WN742: CUN 2026-11-23 14:45:00 → STL 2026-11-23 20:45:00; 1 stop(s) via BNA; 420 minutes. Local airport times.
- WN390: CUN 2026-11-23 14:45:00 → BNA 2026-11-23 16:35:00; layover at BNA: 175 minutes.
- WN742: BNA 2026-11-23 19:30:00 → STL 2026-11-23 20:45:00.
2026-11-20 → 2026-11-23 · $484.50
- Southwest Airlines WN1679 / WN218: STL 2026-11-20 13:05:00 → CUN 2026-11-20 20:25:00; 1 stop(s) via MDW; 380 minutes. Local airport times.
- WN1679: STL 2026-11-20 13:05:00 → MDW 2026-11-20 14:10:00; layover at MDW: 95 minutes.
- WN218: MDW 2026-11-20 15:45:00 → CUN 2026-11-20 20:25:00.
- Southwest Airlines WN1996: CUN 2026-11-23 16:00:00 → STL 2026-11-23 18:10:00; nonstop; 190 minutes. Local airport times.
2026-11-20 → 2026-11-23 · $484.50
- Southwest Airlines WN4164 / WN144: STL 2026-11-20 08:00:00 → CUN 2026-11-20 15:00:00; 1 stop(s) via MCI; 360 minutes. Local airport times.
- WN4164: STL 2026-11-20 08:00:00 → MCI 2026-11-20 09:10:00; layover at MCI: 95 minutes.
- WN144: MCI 2026-11-20 10:45:00 → CUN 2026-11-20 15:00:00.
- Southwest Airlines WN1996: CUN 2026-11-23 16:00:00 → STL 2026-11-23 18:10:00; nonstop; 190 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $494.00
- Southwest Airlines WN4164 / WN144: STL 2026-11-27 08:00:00 → CUN 2026-11-27 15:00:00; 1 stop(s) via MCI; 360 minutes. Local airport times.
- WN4164: STL 2026-11-27 08:00:00 → MCI 2026-11-27 09:10:00; layover at MCI: 95 minutes.
- WN144: MCI 2026-11-27 10:45:00 → CUN 2026-11-27 15:00:00.
- Southwest Airlines WN1996: CUN 2026-12-04 10:45:00 → STL 2026-12-04 12:45:00; nonstop; 180 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $494.00
- Southwest Airlines WN1679 / WN218: STL 2026-11-27 13:05:00 → CUN 2026-11-27 20:25:00; 1 stop(s) via MDW; 380 minutes. Local airport times.
- WN1679: STL 2026-11-27 13:05:00 → MDW 2026-11-27 14:10:00; layover at MDW: 95 minutes.
- WN218: MDW 2026-11-27 15:45:00 → CUN 2026-11-27 20:25:00.
- Southwest Airlines WN1996: CUN 2026-12-04 10:45:00 → STL 2026-12-04 12:45:00; nonstop; 180 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $495.75
- Southwest Airlines WN1995: STL 2026-11-27 12:20:00 → CUN 2026-11-27 16:25:00; nonstop; 185 minutes. Local airport times.
- Southwest Airlines WN390 / WN742: CUN 2026-12-04 14:45:00 → STL 2026-12-04 20:45:00; 1 stop(s) via BNA; 420 minutes. Local airport times.
- WN390: CUN 2026-12-04 14:45:00 → BNA 2026-12-04 16:35:00; layover at BNA: 175 minutes.
- WN742: BNA 2026-12-04 19:30:00 → STL 2026-12-04 20:45:00.
2026-11-27 → 2026-12-04 · $528.60
- American Airlines AA1992 / AA895: STL 2026-11-27 05:00:00 → CUN 2026-11-27 12:29:00; 1 stop(s) via CLT; 389 minutes. Local airport times.
- AA1992: STL 2026-11-27 05:00:00 → CLT 2026-11-27 07:55:00; layover at CLT: 85 minutes.
- AA895: CLT 2026-11-27 09:20:00 → CUN 2026-11-27 12:29:00.
- American Airlines AA3310: CUN 2026-12-04 12:49:00 → STL 2026-12-04 15:21:00; nonstop; 212 minutes. Local airport times.
2026-11-27 → 2026-12-04 · $540.35
- Delta Air Lines DL1102 / DL1939: STL 2026-11-27 14:31:00 → CUN 2026-11-27 21:08:00; 1 stop(s) via ATL; 337 minutes. Local airport times.
- DL1102: STL 2026-11-27 14:31:00 → ATL 2026-11-27 17:05:00; layover at ATL: 84 minutes.
- DL1939: ATL 2026-11-27 18:29:00 → CUN 2026-11-27 21:08:00.
- Delta Air Lines DL595 / DL1403: CUN 2026-12-04 17:35:00 → STL 2026-12-04 23:26:00; 1 stop(s) via ATL; 411 minutes. Local airport times.
- DL595: CUN 2026-12-04 17:35:00 → ATL 2026-12-04 20:25:00; layover at ATL: 135 minutes.
- DL1403: ATL 2026-12-04 22:40:00 → STL 2026-12-04 23:26:00.
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- Hawaii: for Christmas · for Thanksgiving · for spring break · for Presidents' Day weekend · in summer · for 4 days · for 5 days · for a week · for 10 days
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- The Caribbean: for Christmas · for spring break · for Presidents' Day weekend · in winter · in February · for 4 days · for 5 days · for a week
- Costa Rica: for Christmas · for spring break · in winter · for a week · for 10 days
- Central America: for Christmas · for spring break · in winter · for a week · for 10 days
- Europe: in summer · in May · in September · in December · for spring break · for Christmas · for a week · for 10 days · for two weeks
- Italy: in summer · in May · in June · in September · for Christmas · for a week · for 10 days · for two weeks
- Spain: in summer · in May · in September · for spring break · for a week · for 10 days
- Greece: in summer · in May · in June · in September · for a week · for 10 days · for two weeks
- Portugal: in summer · in May · in September · in winter · for 4 days · for a week · for 10 days
- Croatia: in summer · in June · in September · for a week · for 10 days
- Scandinavia: in summer · in winter · in September · for 4 days · for a week · for 10 days
- Eastern Europe: in summer · in May · in September · in December · for a week · for 10 days
- England: in spring · in summer · in fall · for Christmas · for 4 days · for a week · for 10 days
- Scotland: in summer · in fall · for 4 days · for a week
- Ireland: in spring · in summer · in fall · for Christmas · for 4 days · for a week · for 10 days
- Japan: in April · in November · in winter · in summer · for a week · for 10 days · for two weeks
- South Korea: in spring · in fall · for a week · for 10 days
- Asia: in spring · in fall · in winter · for a week · for 10 days · for two weeks
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- Thailand: in winter · in November · in January · in February · for 10 days · for two weeks · for three weeks
- Vietnam: in winter · in November · in February · in spring · for 10 days · for two weeks
- Bali: in summer · in winter · for 10 days · for two weeks · for a month
- India: in winter · in December · for two weeks · for a month
- Australia: in December · in January · in February · in September · for two weeks · for three weeks · for a month
- New Zealand: in December · in January · in February · for two weeks · for three weeks
- South America: in January · in February · in winter · for 10 days · for two weeks
- Colombia: in winter · in spring · for a week · for 10 days
- The Middle East: in winter · for a week · for 10 days
- Turkey: in spring · in summer · in fall · for a week · for 10 days
- Africa: in winter · in fall · for 10 days · for two weeks
- South Africa: in winter · in fall · for 10 days · for two weeks
- Morocco: in spring · in fall · in winter · for a week · for 10 days
- Egypt: in winter · in fall · in spring · for a week · for 10 days
- Canada: in summer · in winter · in fall · for 3 days · for 4 days · for a week
- Florida: for spring break · for Christmas · for Thanksgiving · in winter · for 4 days · for 5 days · for a week
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- Arizona: in spring · in fall · in winter · for spring break · for 3 days · for 4 days · for a week
- Utah: in winter · for Presidents' Day weekend · for MLK weekend · in spring · in summer · for 4 days · for a week
- The Rockies: in summer · in winter · for Presidents' Day weekend · for MLK weekend · for spring break · for 4 days · for a week
- Colorado: in summer · in winter · for Presidents' Day weekend · for MLK weekend · for spring break · for 4 days · for a week
- Montana and Wyoming: in summer · in winter · for a week · for 10 days
- Texas: in spring · in fall · for 3 days · for 4 days
- The Northeast: in fall · in summer · for Thanksgiving · for Christmas · for spring break · for 3 days · for 4 days · for a week
- New England: in fall · in summer · for 3 days · for 4 days · for a week
- The Southeast: in spring · in fall · for 3 days · for 4 days
- Anywhere: for Thanksgiving · for Christmas · for MLK weekend · for Presidents' Day weekend · for spring break · for Easter weekend · for July 4th weekend · for Labor Day weekend · in November · in December · in January · in February · in March · in April · in May · in June · in July · in August · in September · for 4 days · for a week · for two weeks
Fares observed October 23 – 28, 2026. USD for the travelers shown. Search a trip for current prices.
Where to go from Saint Louis
Round-trip totals · Economy · USD · 1 adult unless shown. "From" is a starting total: you pick the return in Axel. Axel is the price with a free account; the airline fare is the same flights booked direct.
| Destination | Why go | Flights | Axel | Dates | |
|---|---|---|---|---|---|
| Austin (AUS) | Austin's live music, barbecue and swimming holes | Nonstop · Southwest · 2h 10m | $321 (airline $340) | May 28–31, 2027 | Check prices |
| Washington (DCA) | Washington's monuments and free museums, minutes from the airport | Nonstop · Southwest, American · 2h | $387 (airline $407) | May 28–31, 2027 | Check prices |
| Denver (DEN) | Denver's breweries and the Rockies within an hour | Nonstop · United, Southwest, Frontier · 2h 22m | $413 (airline $437) | May 28–31, 2027 | Check prices |
| New York (JFK) | New York's museums, Broadway and neighborhoods | 1 stop via Atlanta | $473 (airline $499) | May 28–31, 2027 | Check prices |
| San Diego (SAN) | San Diego's beaches, zoo and Balboa Park | Nonstop · Southwest | $483 (airline $510) | May 28–31, 2027 | Check prices |
| Aruba (AUA) | Aruba's dry, sunny weather outside the hurricane belt | No nonstop seen | $712 (airline $751) | May 28–31, 2027 | Check prices |
| Cancun (CUN) | Cancún's hotel zone, the Riviera Maya and Mayan ruins nearby | Nonstop · Frontier, Southwest, American | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Las Vegas (LAS) | Las Vegas' Strip, shows and day trips to the canyons | Nonstop · Southwest, Frontier | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Orlando (MCO) | Orlando's theme parks | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates | |
| Oahu / Honolulu (HNL) | Waikiki, Diamond Head and Pearl Harbor on Oahu | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates | |
| Los Cabos (SJD) | Los Cabos: resorts, sportfishing and the Sea of Cortez | Nonstop · Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Puerto Vallarta (PVR) | Puerto Vallarta's old town, beaches and Banderas Bay | Nonstop · Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Punta Cana (PUJ) | Punta Cana's long white-sand beaches and all-inclusive resorts | Nonstop · Frontier, Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Montego Bay (MBJ) | Jamaica's resort coast around Montego Bay and Negril | Nonstop · Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Nassau (NAS) | Nassau and Paradise Island, a short flight from the East Coast | No nonstop seen | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| San Juan (SJU) | Old San Juan, beaches and the rainforest, no passport needed from the US | Nonstop · Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Miami (MIA) | Miami's South Beach, Little Havana and art deco | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates | |
| Los Angeles (LAX) | Los Angeles' beaches, Hollywood and museums | Nonstop · Southwest, American | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| San Francisco (SFO) | San Francisco's Golden Gate, cable cars and wine country nearby | Nonstop · United, Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Boston (BOS) | Boston's Freedom Trail, universities and seafood | Nonstop · Southwest, American | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Chicago (ORD) | Chicago's architecture, lakefront and deep-dish | Nonstop · American, United | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Phoenix (PHX) | Phoenix and Scottsdale's resorts, golf and desert hiking | Nonstop · Southwest, American | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| Seattle (SEA) | Seattle's Pike Place Market, waterfront and the mountains | Nonstop · Alaska, Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
| New Orleans (MSY) | New Orleans' French Quarter, food and music | Nonstop · Southwest | No matching fare saved | May 28 – May 31, 2027 (suggested) | Search these dates |
The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.
About these places
Facts checked October 27, 2026. Sources: OPM: federal holidays 2026 and 2027
Keep exploring
Hotels in Cancun with Axel
Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in Cancun has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.
Where to stay: Where to stay in Cancun: the 8 best neighborhoods, ranked · Cancun hotels where a family of four can share one room
Hotels with an Axel review in Cancun: Hotel Antillano Cancun · Hotel Colonial Cancun · Hotel Xbalamqué Boutique & Spa · Adhara Hacienda Cancun · Akuazul Resorts Adults Only · All 160 reviewed hotels in Cancun
For AI assistants
- This page: Best places to fly from Saint Louis for Memorial Day weekend. Where to fly from Saint Louis for Memorial Day weekend: Cancun, Las Vegas, Orlando, Honolulu, San Jose Cabo and Puerto Vallarta and more, priced for Memorial Day weekend 2027 (May 28 to 31), nonstop options first. The cheapest saved fare for each destination, and a link to search your own dates.
- Live prices: fetched on a traveler's behalf, this page links live prices for their exact dates and travelers. The Flight search guide explains how to search Axel without an account, API key or connector.