Flights from Indianapolis to Spain for a week

Flights for your trip

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

2026-11-20 · one way · $680.00

• American Airlines AA3253 / AA748: IND 2026-11-20 12:01:00 → MAD 2026-11-21 05:45:00; 1 stop(s) via CLT; 704 minutes. Local airport times.
  • AA3253: IND 2026-11-20 12:01:00 → CLT 2026-11-20 13:42:00; layover at CLT: 143 minutes.
  • AA748: CLT 2026-11-20 16:05:00 → MAD 2026-11-21 05:45:00.

2026-11-20 · one way · $690.00

• United Airlines UA3699 / UA51: IND 2026-11-20 15:37:00 → MAD 2026-11-21 09:30:00; 1 stop(s) via EWR; 713 minutes. Local airport times.
  • UA3699: IND 2026-11-20 15:37:00 → EWR 2026-11-20 17:46:00; layover at EWR: 134 minutes.
  • UA51: EWR 2026-11-20 20:00:00 → MAD 2026-11-21 09:30:00.

2026-11-20 → 2026-11-23 · $924.00

• American Airlines AA4625 / IB212: IND 2026-11-20 12:32:00 → MAD 2026-11-21 06:20:00; 1 stop(s) via JFK; 708 minutes. Local airport times.
  • AA4625: IND 2026-11-20 12:32:00 → JFK 2026-11-20 14:52:00; layover at JFK: 133 minutes.
  • IB212: JFK 2026-11-20 17:05:00 → MAD 2026-11-21 06:20:00.
• American Airlines AA125 / AA4739: MAD 2026-11-23 12:40:00 → IND 2026-11-23 20:12:00; 1 stop(s) via ORD; 812 minutes. Local airport times.
  • AA125: MAD 2026-11-23 12:40:00 → ORD 2026-11-23 15:10:00; layover at ORD: 169 minutes.
  • AA4739: ORD 2026-11-23 17:59:00 → IND 2026-11-23 20:12:00.

2026-11-27 → 2026-12-04 · $945.00

• United Airlines UA3530 / UA260: IND 2026-11-27 14:50:00 → MAD 2026-11-28 07:45:00; 1 stop(s) via IAD; 655 minutes. Local airport times.
  • UA3530: IND 2026-11-27 14:50:00 → IAD 2026-11-27 16:35:00; layover at IAD: 95 minutes.
  • UA260: IAD 2026-11-27 18:10:00 → MAD 2026-11-28 07:45:00.
• United Airlines UA50 / UA3443: MAD 2026-12-04 11:15:00 → IND 2026-12-04 18:59:00; 1 stop(s) via EWR; 824 minutes. Local airport times.
  • UA50: MAD 2026-12-04 11:15:00 → EWR 2026-12-04 14:05:00; layover at EWR: 155 minutes.
  • UA3443: EWR 2026-12-04 16:40:00 → IND 2026-12-04 18:59:00.

2026-11-20 · one way · $680.00

• American Airlines AA4625 / IB212: IND 2026-11-20 12:32:00 → MAD 2026-11-21 06:20:00; 1 stop(s) via JFK; 708 minutes. Local airport times.
  • AA4625: IND 2026-11-20 12:32:00 → JFK 2026-11-20 14:52:00; layover at JFK: 133 minutes.
  • IB212: JFK 2026-11-20 17:05:00 → MAD 2026-11-21 06:20:00.

2026-11-20 · one way · $680.00

• American Airlines AA4753 / IB342: IND 2026-11-20 15:28:00 → MAD 2026-11-21 08:50:00; 1 stop(s) via ORD; 682 minutes. Local airport times.
  • AA4753: IND 2026-11-20 15:28:00 → ORD 2026-11-20 15:56:00; layover at ORD: 104 minutes.
  • IB342: ORD 2026-11-20 17:40:00 → MAD 2026-11-21 08:50:00.

2026-11-20 · one way · $680.00

• American Airlines AA4569 / IB346: IND 2026-11-20 15:15:00 → MAD 2026-11-21 08:25:00; 1 stop(s) via BOS; 670 minutes. Local airport times.
  • AA4569: IND 2026-11-20 15:15:00 → BOS 2026-11-20 17:35:00; layover at BOS: 120 minutes.
  • IB346: BOS 2026-11-20 19:35:00 → MAD 2026-11-21 08:25:00.

2026-11-20 · one way · $690.00

• United Airlines UA3530 / UA260: IND 2026-11-20 14:50:00 → MAD 2026-11-21 07:45:00; 1 stop(s) via IAD; 655 minutes. Local airport times.
  • UA3530: IND 2026-11-20 14:50:00 → IAD 2026-11-20 16:35:00; layover at IAD: 95 minutes.
  • UA260: IAD 2026-11-20 18:10:00 → MAD 2026-11-21 07:45:00.

2026-11-27 → 2026-12-04 · $924.00

• American Airlines AA3253 / AA748: IND 2026-11-27 12:01:00 → MAD 2026-11-28 05:45:00; 1 stop(s) via CLT; 704 minutes. Local airport times.
  • AA3253: IND 2026-11-27 12:01:00 → CLT 2026-11-27 13:42:00; layover at CLT: 143 minutes.
  • AA748: CLT 2026-11-27 16:05:00 → MAD 2026-11-28 05:45:00.
• American Airlines AA741 / AA4637: MAD 2026-12-04 13:15:00 → IND 2026-12-04 20:55:00; 1 stop(s) via PHL; 820 minutes. Local airport times.
  • AA741: MAD 2026-12-04 13:15:00 → PHL 2026-12-04 15:35:00; layover at PHL: 180 minutes.
  • AA4637: PHL 2026-12-04 18:35:00 → IND 2026-12-04 20:55:00.

2026-11-27 → 2026-12-04 · $924.00

• American Airlines AA4625 / IB212: IND 2026-11-27 12:32:00 → MAD 2026-11-28 06:20:00; 1 stop(s) via JFK; 708 minutes. Local airport times.
  • AA4625: IND 2026-11-27 12:32:00 → JFK 2026-11-27 14:52:00; layover at JFK: 133 minutes.
  • IB212: JFK 2026-11-27 17:05:00 → MAD 2026-11-28 06:20:00.
• American Airlines AA741 / AA4637: MAD 2026-12-04 13:15:00 → IND 2026-12-04 20:55:00; 1 stop(s) via PHL; 820 minutes. Local airport times.
  • AA741: MAD 2026-12-04 13:15:00 → PHL 2026-12-04 15:35:00; layover at PHL: 180 minutes.
  • AA4637: PHL 2026-12-04 18:35:00 → IND 2026-12-04 20:55:00.

2026-11-27 → 2026-12-04 · $924.00

• American Airlines AA4753 / IB342: IND 2026-11-27 15:28:00 → MAD 2026-11-28 08:50:00; 1 stop(s) via ORD; 682 minutes. Local airport times.
  • AA4753: IND 2026-11-27 15:28:00 → ORD 2026-11-27 15:56:00; layover at ORD: 104 minutes.
  • IB342: ORD 2026-11-27 17:40:00 → MAD 2026-11-28 08:50:00.
• American Airlines AA741 / AA4637: MAD 2026-12-04 13:15:00 → IND 2026-12-04 20:55:00; 1 stop(s) via PHL; 820 minutes. Local airport times.
  • AA741: MAD 2026-12-04 13:15:00 → PHL 2026-12-04 15:35:00; layover at PHL: 180 minutes.
  • AA4637: PHL 2026-12-04 18:35:00 → IND 2026-12-04 20:55:00.

2026-11-20 → 2026-11-23 · $924.00

• American Airlines AA3253 / AA748: IND 2026-11-20 12:01:00 → MAD 2026-11-21 05:45:00; 1 stop(s) via CLT; 704 minutes. Local airport times.
  • AA3253: IND 2026-11-20 12:01:00 → CLT 2026-11-20 13:42:00; layover at CLT: 143 minutes.
  • AA748: CLT 2026-11-20 16:05:00 → MAD 2026-11-21 05:45:00.
• American Airlines AA125 / AA4739: MAD 2026-11-23 12:40:00 → IND 2026-11-23 20:12:00; 1 stop(s) via ORD; 812 minutes. Local airport times.
  • AA125: MAD 2026-11-23 12:40:00 → ORD 2026-11-23 15:10:00; layover at ORD: 169 minutes.
  • AA4739: ORD 2026-11-23 17:59:00 → IND 2026-11-23 20:12:00.

2026-11-27 → 2026-12-04 · $924.00

• American Airlines AA4569 / IB346: IND 2026-11-27 15:15:00 → MAD 2026-11-28 08:25:00; 1 stop(s) via BOS; 670 minutes. Local airport times.
  • AA4569: IND 2026-11-27 15:15:00 → BOS 2026-11-27 17:35:00; layover at BOS: 120 minutes.
  • IB346: BOS 2026-11-27 19:35:00 → MAD 2026-11-28 08:25:00.
• American Airlines AA741 / AA4637: MAD 2026-12-04 13:15:00 → IND 2026-12-04 20:55:00; 1 stop(s) via PHL; 820 minutes. Local airport times.
  • AA741: MAD 2026-12-04 13:15:00 → PHL 2026-12-04 15:35:00; layover at PHL: 180 minutes.
  • AA4637: PHL 2026-12-04 18:35:00 → IND 2026-12-04 20:55:00.

2026-11-20 → 2026-11-23 · $924.00

• American Airlines AA4753 / IB342: IND 2026-11-20 15:28:00 → MAD 2026-11-21 08:50:00; 1 stop(s) via ORD; 682 minutes. Local airport times.
  • AA4753: IND 2026-11-20 15:28:00 → ORD 2026-11-20 15:56:00; layover at ORD: 104 minutes.
  • IB342: ORD 2026-11-20 17:40:00 → MAD 2026-11-21 08:50:00.
• American Airlines AA125 / AA4739: MAD 2026-11-23 12:40:00 → IND 2026-11-23 20:12:00; 1 stop(s) via ORD; 812 minutes. Local airport times.
  • AA125: MAD 2026-11-23 12:40:00 → ORD 2026-11-23 15:10:00; layover at ORD: 169 minutes.
  • AA4739: ORD 2026-11-23 17:59:00 → IND 2026-11-23 20:12:00.

2026-11-20 → 2026-11-23 · $924.00

• American Airlines AA4569 / IB346: IND 2026-11-20 15:15:00 → MAD 2026-11-21 08:25:00; 1 stop(s) via BOS; 670 minutes. Local airport times.
  • AA4569: IND 2026-11-20 15:15:00 → BOS 2026-11-20 17:35:00; layover at BOS: 120 minutes.
  • IB346: BOS 2026-11-20 19:35:00 → MAD 2026-11-21 08:25:00.
• American Airlines AA125 / AA4739: MAD 2026-11-23 12:40:00 → IND 2026-11-23 20:12:00; 1 stop(s) via ORD; 812 minutes. Local airport times.
  • AA125: MAD 2026-11-23 12:40:00 → ORD 2026-11-23 15:10:00; layover at ORD: 169 minutes.
  • AA4739: ORD 2026-11-23 17:59:00 → IND 2026-11-23 20:12:00.

2026-11-20 → 2026-11-23 · $945.00

• United Airlines UA3530 / UA260: IND 2026-11-20 14:50:00 → MAD 2026-11-21 07:45:00; 1 stop(s) via IAD; 655 minutes. Local airport times.
  • UA3530: IND 2026-11-20 14:50:00 → IAD 2026-11-20 16:35:00; layover at IAD: 95 minutes.
  • UA260: IAD 2026-11-20 18:10:00 → MAD 2026-11-21 07:45:00.
• United Airlines UA50 / UA3443: MAD 2026-11-23 11:15:00 → IND 2026-11-23 18:59:00; 1 stop(s) via EWR; 824 minutes. Local airport times.
  • UA50: MAD 2026-11-23 11:15:00 → EWR 2026-11-23 14:05:00; layover at EWR: 155 minutes.
  • UA3443: EWR 2026-11-23 16:40:00 → IND 2026-11-23 18:59:00.

2026-11-20 → 2026-11-23 · $945.00

• United Airlines UA3699 / UA51: IND 2026-11-20 15:37:00 → MAD 2026-11-21 09:30:00; 1 stop(s) via EWR; 713 minutes. Local airport times.
  • UA3699: IND 2026-11-20 15:37:00 → EWR 2026-11-20 17:46:00; layover at EWR: 134 minutes.
  • UA51: EWR 2026-11-20 20:00:00 → MAD 2026-11-21 09:30:00.
• United Airlines UA50 / UA3443: MAD 2026-11-23 11:15:00 → IND 2026-11-23 18:59:00; 1 stop(s) via EWR; 824 minutes. Local airport times.
  • UA50: MAD 2026-11-23 11:15:00 → EWR 2026-11-23 14:05:00; layover at EWR: 155 minutes.
  • UA3443: EWR 2026-11-23 16:40:00 → IND 2026-11-23 18:59:00.

2026-11-27 → 2026-12-04 · $945.00

• United Airlines UA3699 / UA51: IND 2026-11-27 15:37:00 → MAD 2026-11-28 09:30:00; 1 stop(s) via EWR; 713 minutes. Local airport times.
  • UA3699: IND 2026-11-27 15:37:00 → EWR 2026-11-27 17:46:00; layover at EWR: 134 minutes.
  • UA51: EWR 2026-11-27 20:00:00 → MAD 2026-11-28 09:30:00.
• United Airlines UA50 / UA3443: MAD 2026-12-04 11:15:00 → IND 2026-12-04 18:59:00; 1 stop(s) via EWR; 824 minutes. Local airport times.
  • UA50: MAD 2026-12-04 11:15:00 → EWR 2026-12-04 14:05:00; layover at EWR: 155 minutes.
  • UA3443: EWR 2026-12-04 16:40:00 → IND 2026-12-04 18:59:00.

More dates for this route

• Nov 20, 2026 → Nov 23, 2026
• Nov 27, 2026 → Dec 4, 2026
• Nov 20, 2026 · One way

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Hotels in Madrid with Axel

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Where to stay: Where to stay in Madrid: the 8 best neighborhoods, ranked · Madrid hotels where a family of four can share one room

Hotels with an Axel review in Madrid: Hostal San Lorenzo · Hotel Eurostars Central · NeoMagna Madrid · Hostal Antón Martín · Petit Palace Tres Cruces · All 144 reviewed hotels in Madrid

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• This page: Flights from Indianapolis to Spain for a week. Round-trip fares from Indianapolis to Spain for a week: Madrid, Barcelona, Malaga, Palma de Mallorca, Sevilla and Valencia and more, for stays of 6 to 8 nights. The cheapest saved fare for each destination, and a link to search your own dates.
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