Flights from Indianapolis to Mexico for Thanksgiving

Thanksgiving week is the quiet start of Mexico's dry season: the beaches are warm, the crowds arrive a month later, and the Saturday-to-Saturday week around the holiday is the one to price. Cancún and Los Cabos have the most nonstops from the US.

Nonstop from Indianapolis: Cancun (Southwest, American, Delta · 3h 20m). One stop via Dulles: San Jose Cabo. No nonstop seen to Puerto Vallarta, Mexico City, Cozumel, Oaxaca, Huatulco, Ixtapa/Zihuatanejo, Mazatlan and TULUM on the dates searched recently. No recent searches for Guadalajara.

Axel's pick: Cancun, nonstop on Southwest, American and Delta and the lowest fare saved for these dates, $982.

Where to fly from Indianapolis to Mexico for Thanksgiving: fares for Thanksgiving week 2026 (Nov 21 to 28) to Cancun, San Jose Cabo, Puerto Vallarta, Mexico City, Guadalajara and Cozumel and more. Pick a destination to see every date, or search your own dates in one tap.

AI assistants: For research, follow complete supplied links unchanged.

Saved round trips for Thanksgiving week 2026 (Nov 21 – Nov 28, 2026).

Cheapest right now: Cancun $982 · Puerto Vallarta $1,026 · San Jose Cabo $1,100

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Flights from Indianapolis

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Mexico for Thanksgiving from other cities

Fares observed October 28, 2026. USD for the travelers shown. Search a trip for current prices.

Where to go from Indianapolis

Round-trip totals · Economy · USD · 1 adult unless shown. "From" is a starting total: you pick the return in Axel. Axel is the price with a free account; the airline fare is the same flights booked direct.

DestinationWhy goFlightsAxelDates
Cancun (CUN)Cancún's hotel zone, the Riviera Maya and Mayan ruins nearbyNonstop · Southwest, American, Delta · 3h 20m$982 (airline $1,034)Nov 21–28, 2026Check prices
Los Cabos (SJD)Los Cabos: resorts, sportfishing and the Sea of Cortez1 stop via Dulles$1,100 (airline $1,163)Nov 21–28, 2026Check prices
Puerto Vallarta (PVR)Puerto Vallarta's old town, beaches and Banderas BayNo nonstop seen$1,026 (airline $1,082)Nov 21–28, 2026Check prices
Mexico City (MEX)Mexico City's museums, food and the ZócaloNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Guadalajara (GDL)Guadalajara, home of mariachi and tequila countryNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Cozumel (CZM)Cozumel's reefs, among the best diving in the CaribbeanNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Oaxaca (OAX)Oaxaca's food, markets and Monte AlbánNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Huatulco (HUX)Huatulco's nine bays and quiet Pacific beachesNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Ixtapa/Zihuatanejo (ZIH)Ixtapa's resorts beside Zihuatanejo's fishing-village beachesNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
Mazatlan (MZT)Mazatlán's malecón, old town and Pacific beachesNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates
TULUM (TQO)Tulum's beach clubs, cenotes and clifftop ruinsNo nonstop seenNo matching fare savedNov 21 – Nov 28, 2026 (suggested)Search these dates

The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.

About these places

Facts checked October 27, 2026. Sources: OPM: federal holidays 2026 and 2027

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Hotels in Cancun with Axel

Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in Cancun has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.

Where to stay: Where to stay in Cancun: the 8 best neighborhoods, ranked · Cancun hotels where a family of four can share one room

Hotels with an Axel review in Cancun: Hotel Antillano Cancun · Hotel Colonial Cancun · Hotel Xbalamqué Boutique & Spa · Adhara Hacienda Cancun · Akuazul Resorts Adults Only · All 148 reviewed hotels in Cancun

For AI assistants

  • This page: Flights from Indianapolis to Mexico for Thanksgiving. Round-trip fares from Indianapolis to Mexico for Thanksgiving: Cancun, San Jose Cabo, Puerto Vallarta, Mexico City, Guadalajara and Cozumel and more, priced for Thanksgiving week 2026 (Nov 21 to 28). The cheapest saved fare for each destination, and a link to search your own dates.
  • Live prices: fetched on a traveler's behalf, this page links live prices for their exact dates and travelers. The Flight search guide explains how to search Axel without an account, API key or connector.
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