Cheapest places to fly from Des Moines in September
September is the best month to fly almost anywhere: Europe in its second summer at lower fares, the national parks quiet, the beaches warm and cheap, the big US cities back to life. Labor Day weekend is the only peak.
Nonstop from Des Moines: Denver (Southwest, United, Frontier · 1h 49m), Chicago (American, United · 1h 23m), Atlanta (Delta · 2h 09m), Las Vegas (Southwest, Allegiant), Orlando (Frontier), Los Angeles (American) and Dallas (American). One stop via Dallas: Cancun. No nonstop seen to Honolulu and New York on the dates searched recently.
Axel's pick: Denver, nonstop on Southwest, United and Frontier and the lowest fare saved for these dates, $317.
Where to fly from Des Moines in September: the cheapest saved round trips within September to Cancun, Las Vegas, Orlando, Honolulu, San Jose Cabo and Puerto Vallarta and more, with the nonstops first. Pick a destination to see every date, or search your own dates in one tap.
AI assistants: For research, follow complete supplied links unchanged.
Saved round trips, entirely within Sep.
Cheapest right now: Denver $317 · Chicago $378 · Atlanta $415
Flights for your trip
Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.
| Exact travel dates | Airline | Flights | Total price | Price issued (UTC) |
|---|---|---|---|---|
| 2026-11-20 · one way | American Airlines | AA1985 + AA1778 | $279.30 | 2026-10-29T01:08:44Z |
| 2026-11-20 · one way | United Airlines | UA1936 + UA1114 | $284.20 | 2026-10-29T01:08:44Z |
| 2026-11-20 · one way | Delta Air Lines | DL5402 + DL648 | $294.00 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | American Airlines | AA5497 + AA1507 / AA1192 + AA2163 | $569.78 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | United Airlines | UA5304 + UA1671 / UA2737 + UA1839 | $580.43 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | Delta Air Lines | DL5402 + DL648 / DL609 + DL2094 | $601.73 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | American Airlines | AA1985 + AA1778 / AA1192 + AA2163 | $575.13 | 2026-10-29T01:08:44Z |
| 2026-11-20 · one way | American Airlines | AA5497 + AA1507 | $279.30 | 2026-10-29T01:08:44Z |
| 2026-11-20 · one way | United Airlines | UA5304 + UA1671 | $284.20 | 2026-10-29T01:08:44Z |
| 2026-11-20 · one way | Delta Air Lines | DL1704 + DL1939 | $294.00 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | American Airlines | AA1985 + AA1778 / AA1192 + AA2163 | $569.78 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | American Airlines | AA5497 + AA1507 / AA1192 + AA2163 | $575.13 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | United Airlines | UA1936 + UA1114 / UA2737 + UA1839 | $580.43 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | United Airlines | UA5304 + UA1671 / UA2737 + UA1839 | $585.88 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | United Airlines | UA1936 + UA1114 / UA2737 + UA1839 | $585.88 | 2026-10-29T01:08:44Z |
| 2026-11-20 → 2026-11-23 | Delta Air Lines | DL1704 + DL1939 / DL609 + DL2094 | $601.73 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | Delta Air Lines | DL5402 + DL648 / DL609 + DL2094 | $607.38 | 2026-10-29T01:08:44Z |
| 2026-11-27 → 2026-12-04 | Delta Air Lines | DL1704 + DL1939 / DL609 + DL2094 | $607.38 | 2026-10-29T01:08:44Z |
2026-11-20 · one way · $279.30
- American Airlines AA1985 / AA1778: DSM 2026-11-20 08:07:00 → CUN 2026-11-20 16:11:00; 1 stop(s) via CLT; 424 minutes. Local airport times.
- AA1985: DSM 2026-11-20 08:07:00 → CLT 2026-11-20 11:30:00; layover at CLT: 90 minutes.
- AA1778: CLT 2026-11-20 13:00:00 → CUN 2026-11-20 16:11:00.
2026-11-20 · one way · $284.20
- United Airlines UA1936 / UA1114: DSM 2026-11-20 08:00:00 → CUN 2026-11-20 17:50:00; 1 stop(s) via IAH; 530 minutes. Local airport times.
- UA1936: DSM 2026-11-20 08:00:00 → IAH 2026-11-20 10:33:00; layover at IAH: 234 minutes.
- UA1114: IAH 2026-11-20 14:27:00 → CUN 2026-11-20 17:50:00.
2026-11-20 · one way · $294.00
- Delta Air Lines DL5402 / DL648: DSM 2026-11-20 06:45:00 → CUN 2026-11-20 15:30:00; 1 stop(s) via MSP; 465 minutes. Local airport times.
- DL5402: DSM 2026-11-20 06:45:00 → MSP 2026-11-20 08:01:00; layover at MSP: 129 minutes.
- DL648: MSP 2026-11-20 10:10:00 → CUN 2026-11-20 15:30:00.
2026-11-20 → 2026-11-23 · $569.78
- American Airlines AA5497 / AA1507: DSM 2026-11-20 09:45:00 → CUN 2026-11-20 17:35:00; 1 stop(s) via DFW; 410 minutes. Local airport times.
- AA5497: DSM 2026-11-20 09:45:00 → DFW 2026-11-20 12:12:00; layover at DFW: 96 minutes.
- AA1507: DFW 2026-11-20 13:48:00 → CUN 2026-11-20 17:35:00.
- American Airlines AA1192 / AA2163: CUN 2026-11-23 17:13:00 → DSM 2026-11-24 00:26:00; 1 stop(s) via CLT; 493 minutes. Local airport times.
- AA1192: CUN 2026-11-23 17:13:00 → CLT 2026-11-23 20:14:00; layover at CLT: 156 minutes.
- AA2163: CLT 2026-11-23 22:50:00 → DSM 2026-11-24 00:26:00.
2026-11-20 → 2026-11-23 · $580.43
- United Airlines UA5304 / UA1671: DSM 2026-11-20 11:22:00 → CUN 2026-11-20 20:44:00; 1 stop(s) via ORD; 502 minutes. Local airport times.
- UA5304: DSM 2026-11-20 11:22:00 → ORD 2026-11-20 12:58:00; layover at ORD: 168 minutes.
- UA1671: ORD 2026-11-20 15:46:00 → CUN 2026-11-20 20:44:00.
- United Airlines UA2737 / UA1839: CUN 2026-11-23 14:55:00 → DSM 2026-11-23 21:55:00; 1 stop(s) via ORD; 480 minutes. Local airport times.
- UA2737: CUN 2026-11-23 14:55:00 → ORD 2026-11-23 17:59:00; layover at ORD: 146 minutes.
- UA1839: ORD 2026-11-23 20:25:00 → DSM 2026-11-23 21:55:00.
2026-11-20 → 2026-11-23 · $601.73
- Delta Air Lines DL5402 / DL648: DSM 2026-11-20 06:45:00 → CUN 2026-11-20 15:30:00; 1 stop(s) via MSP; 465 minutes. Local airport times.
- DL5402: DSM 2026-11-20 06:45:00 → MSP 2026-11-20 08:01:00; layover at MSP: 129 minutes.
- DL648: MSP 2026-11-20 10:10:00 → CUN 2026-11-20 15:30:00.
- Delta Air Lines DL609 / DL2094: CUN 2026-11-23 08:15:00 → DSM 2026-11-23 14:13:00; 1 stop(s) via ATL; 418 minutes. Local airport times.
- DL609: CUN 2026-11-23 08:15:00 → ATL 2026-11-23 10:57:00; layover at ATL: 122 minutes.
- DL2094: ATL 2026-11-23 12:59:00 → DSM 2026-11-23 14:13:00.
2026-11-27 → 2026-12-04 · $575.13
- American Airlines AA1985 / AA1778: DSM 2026-11-27 08:07:00 → CUN 2026-11-27 16:11:00; 1 stop(s) via CLT; 424 minutes. Local airport times.
- AA1985: DSM 2026-11-27 08:07:00 → CLT 2026-11-27 11:30:00; layover at CLT: 90 minutes.
- AA1778: CLT 2026-11-27 13:00:00 → CUN 2026-11-27 16:11:00.
- American Airlines AA1192 / AA2163: CUN 2026-12-04 17:13:00 → DSM 2026-12-05 00:26:00; 1 stop(s) via CLT; 493 minutes. Local airport times.
- AA1192: CUN 2026-12-04 17:13:00 → CLT 2026-12-04 20:14:00; layover at CLT: 156 minutes.
- AA2163: CLT 2026-12-04 22:50:00 → DSM 2026-12-05 00:26:00.
2026-11-20 · one way · $279.30
- American Airlines AA5497 / AA1507: DSM 2026-11-20 09:45:00 → CUN 2026-11-20 17:35:00; 1 stop(s) via DFW; 410 minutes. Local airport times.
- AA5497: DSM 2026-11-20 09:45:00 → DFW 2026-11-20 12:12:00; layover at DFW: 96 minutes.
- AA1507: DFW 2026-11-20 13:48:00 → CUN 2026-11-20 17:35:00.
2026-11-20 · one way · $284.20
- United Airlines UA5304 / UA1671: DSM 2026-11-20 11:22:00 → CUN 2026-11-20 20:44:00; 1 stop(s) via ORD; 502 minutes. Local airport times.
- UA5304: DSM 2026-11-20 11:22:00 → ORD 2026-11-20 12:58:00; layover at ORD: 168 minutes.
- UA1671: ORD 2026-11-20 15:46:00 → CUN 2026-11-20 20:44:00.
2026-11-20 · one way · $294.00
- Delta Air Lines DL1704 / DL1939: DSM 2026-11-20 11:36:00 → CUN 2026-11-20 21:08:00; 1 stop(s) via ATL; 512 minutes. Local airport times.
- DL1704: DSM 2026-11-20 11:36:00 → ATL 2026-11-20 14:35:00; layover at ATL: 234 minutes.
- DL1939: ATL 2026-11-20 18:29:00 → CUN 2026-11-20 21:08:00.
2026-11-20 → 2026-11-23 · $569.78
- American Airlines AA1985 / AA1778: DSM 2026-11-20 08:07:00 → CUN 2026-11-20 16:11:00; 1 stop(s) via CLT; 424 minutes. Local airport times.
- AA1985: DSM 2026-11-20 08:07:00 → CLT 2026-11-20 11:30:00; layover at CLT: 90 minutes.
- AA1778: CLT 2026-11-20 13:00:00 → CUN 2026-11-20 16:11:00.
- American Airlines AA1192 / AA2163: CUN 2026-11-23 17:13:00 → DSM 2026-11-24 00:26:00; 1 stop(s) via CLT; 493 minutes. Local airport times.
- AA1192: CUN 2026-11-23 17:13:00 → CLT 2026-11-23 20:14:00; layover at CLT: 156 minutes.
- AA2163: CLT 2026-11-23 22:50:00 → DSM 2026-11-24 00:26:00.
2026-11-27 → 2026-12-04 · $575.13
- American Airlines AA5497 / AA1507: DSM 2026-11-27 09:45:00 → CUN 2026-11-27 17:35:00; 1 stop(s) via DFW; 410 minutes. Local airport times.
- AA5497: DSM 2026-11-27 09:45:00 → DFW 2026-11-27 12:12:00; layover at DFW: 96 minutes.
- AA1507: DFW 2026-11-27 13:48:00 → CUN 2026-11-27 17:35:00.
- American Airlines AA1192 / AA2163: CUN 2026-12-04 17:13:00 → DSM 2026-12-05 00:26:00; 1 stop(s) via CLT; 493 minutes. Local airport times.
- AA1192: CUN 2026-12-04 17:13:00 → CLT 2026-12-04 20:14:00; layover at CLT: 156 minutes.
- AA2163: CLT 2026-12-04 22:50:00 → DSM 2026-12-05 00:26:00.
2026-11-20 → 2026-11-23 · $580.43
- United Airlines UA1936 / UA1114: DSM 2026-11-20 08:00:00 → CUN 2026-11-20 17:50:00; 1 stop(s) via IAH; 530 minutes. Local airport times.
- UA1936: DSM 2026-11-20 08:00:00 → IAH 2026-11-20 10:33:00; layover at IAH: 234 minutes.
- UA1114: IAH 2026-11-20 14:27:00 → CUN 2026-11-20 17:50:00.
- United Airlines UA2737 / UA1839: CUN 2026-11-23 14:55:00 → DSM 2026-11-23 21:55:00; 1 stop(s) via ORD; 480 minutes. Local airport times.
- UA2737: CUN 2026-11-23 14:55:00 → ORD 2026-11-23 17:59:00; layover at ORD: 146 minutes.
- UA1839: ORD 2026-11-23 20:25:00 → DSM 2026-11-23 21:55:00.
2026-11-27 → 2026-12-04 · $585.88
- United Airlines UA5304 / UA1671: DSM 2026-11-27 11:22:00 → CUN 2026-11-27 20:44:00; 1 stop(s) via ORD; 502 minutes. Local airport times.
- UA5304: DSM 2026-11-27 11:22:00 → ORD 2026-11-27 12:58:00; layover at ORD: 168 minutes.
- UA1671: ORD 2026-11-27 15:46:00 → CUN 2026-11-27 20:44:00.
- United Airlines UA2737 / UA1839: CUN 2026-12-04 14:55:00 → DSM 2026-12-04 21:55:00; 1 stop(s) via ORD; 480 minutes. Local airport times.
- UA2737: CUN 2026-12-04 14:55:00 → ORD 2026-12-04 17:59:00; layover at ORD: 146 minutes.
- UA1839: ORD 2026-12-04 20:25:00 → DSM 2026-12-04 21:55:00.
2026-11-27 → 2026-12-04 · $585.88
- United Airlines UA1936 / UA1114: DSM 2026-11-27 08:00:00 → CUN 2026-11-27 17:50:00; 1 stop(s) via IAH; 530 minutes. Local airport times.
- UA1936: DSM 2026-11-27 08:00:00 → IAH 2026-11-27 10:33:00; layover at IAH: 234 minutes.
- UA1114: IAH 2026-11-27 14:27:00 → CUN 2026-11-27 17:50:00.
- United Airlines UA2737 / UA1839: CUN 2026-12-04 14:55:00 → DSM 2026-12-04 21:55:00; 1 stop(s) via ORD; 480 minutes. Local airport times.
- UA2737: CUN 2026-12-04 14:55:00 → ORD 2026-12-04 17:59:00; layover at ORD: 146 minutes.
- UA1839: ORD 2026-12-04 20:25:00 → DSM 2026-12-04 21:55:00.
2026-11-20 → 2026-11-23 · $601.73
- Delta Air Lines DL1704 / DL1939: DSM 2026-11-20 11:36:00 → CUN 2026-11-20 21:08:00; 1 stop(s) via ATL; 512 minutes. Local airport times.
- DL1704: DSM 2026-11-20 11:36:00 → ATL 2026-11-20 14:35:00; layover at ATL: 234 minutes.
- DL1939: ATL 2026-11-20 18:29:00 → CUN 2026-11-20 21:08:00.
- Delta Air Lines DL609 / DL2094: CUN 2026-11-23 08:15:00 → DSM 2026-11-23 14:13:00; 1 stop(s) via ATL; 418 minutes. Local airport times.
- DL609: CUN 2026-11-23 08:15:00 → ATL 2026-11-23 10:57:00; layover at ATL: 122 minutes.
- DL2094: ATL 2026-11-23 12:59:00 → DSM 2026-11-23 14:13:00.
2026-11-27 → 2026-12-04 · $607.38
- Delta Air Lines DL5402 / DL648: DSM 2026-11-27 06:45:00 → CUN 2026-11-27 15:30:00; 1 stop(s) via MSP; 465 minutes. Local airport times.
- DL5402: DSM 2026-11-27 06:45:00 → MSP 2026-11-27 08:01:00; layover at MSP: 129 minutes.
- DL648: MSP 2026-11-27 10:10:00 → CUN 2026-11-27 15:30:00.
- Delta Air Lines DL609 / DL2094: CUN 2026-12-04 08:15:00 → DSM 2026-12-04 14:13:00; 1 stop(s) via ATL; 418 minutes. Local airport times.
- DL609: CUN 2026-12-04 08:15:00 → ATL 2026-12-04 10:57:00; layover at ATL: 122 minutes.
- DL2094: ATL 2026-12-04 12:59:00 → DSM 2026-12-04 14:13:00.
2026-11-27 → 2026-12-04 · $607.38
- Delta Air Lines DL1704 / DL1939: DSM 2026-11-27 11:36:00 → CUN 2026-11-27 21:08:00; 1 stop(s) via ATL; 512 minutes. Local airport times.
- DL1704: DSM 2026-11-27 11:36:00 → ATL 2026-11-27 14:35:00; layover at ATL: 234 minutes.
- DL1939: ATL 2026-11-27 18:29:00 → CUN 2026-11-27 21:08:00.
- Delta Air Lines DL609 / DL2094: CUN 2026-12-04 08:15:00 → DSM 2026-12-04 14:13:00; 1 stop(s) via ATL; 418 minutes. Local airport times.
- DL609: CUN 2026-12-04 08:15:00 → ATL 2026-12-04 10:57:00; layover at ATL: 122 minutes.
- DL2094: ATL 2026-12-04 12:59:00 → DSM 2026-12-04 14:13:00.
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- Anywhere: for Thanksgiving · for Christmas · for MLK weekend · for Presidents' Day weekend · for spring break · for Easter weekend · for Memorial Day weekend · for July 4th weekend · for Labor Day weekend · in November · in December · in January · in February · in March · in April · in May · in June · in July · in August · for 4 days · for a week · for two weeks
Fares observed October 28, 2026. USD for the travelers shown. Search a trip for current prices.
Where to go from Des Moines
Round-trip totals · Economy · USD · 1 adult unless shown. "From" is a starting total: you pick the return in Axel. Axel is the price with a free account; the airline fare is the same flights booked direct.
| Destination | Why go | Flights | Axel | Dates | |
|---|---|---|---|---|---|
| Denver (DEN) | Denver's breweries and the Rockies within an hour | Nonstop · Southwest, United, Frontier · 1h 49m | $317 (airline $335) | Sep 11–18, 2027 | Check prices |
| Chicago (ORD) | Chicago's architecture, lakefront and deep-dish | Nonstop · American, United · 1h 23m | $378 (airline $399) | Sep 3–6, 2027 | Check prices |
| Atlanta (ATL) | Atlanta's museums, food and the civil rights trail | Nonstop · Delta · 2h 09m | $415 (airline $439) | Sep 11–18, 2027 | Check prices |
| Las Vegas (LAS) | Las Vegas' Strip, shows and day trips to the canyons | Nonstop · Southwest, Allegiant | $599 (airline $633) | Sep 3–6, 2027 | Check prices |
| Cancun (CUN) | Cancún's hotel zone, the Riviera Maya and Mayan ruins nearby | 1 stop via Dallas | $601 (airline $635) | Sep 11–18, 2027 | Check prices |
| Orlando (MCO) | Orlando's theme parks | Nonstop · Frontier | No matching fare saved | Sep 11 – Sep 18, 2027 (suggested) | Search these dates |
| Oahu / Honolulu (HNL) | Waikiki, Diamond Head and Pearl Harbor on Oahu | No nonstop seen | No matching fare saved | Sep 11 – Sep 18, 2027 (suggested) | Search these dates |
| Los Angeles (LAX) | Los Angeles' beaches, Hollywood and museums | Nonstop · American | No matching fare saved | Sep 11 – Sep 18, 2027 (suggested) | Search these dates |
| New York (JFK) | New York's museums, Broadway and neighborhoods | No nonstop seen | No matching fare saved | Sep 11 – Sep 18, 2027 (suggested) | Search these dates |
| Dallas (DFW) | Dallas and Fort Worth's museums, stockyards and barbecue | Nonstop · American | No matching fare saved | Sep 11 – Sep 18, 2027 (suggested) | Search these dates |
The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.
Keep exploring
Hotels in Cancun with Axel
Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in Cancun has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.
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For AI assistants
- This page: Cheapest places to fly from Des Moines in September. Where to fly from Des Moines in September: Cancun, Las Vegas, Orlando, Honolulu, San Jose Cabo and Puerto Vallarta and more. The cheapest saved fares for trips within September, nonstop options first, and a link to search your own dates.
- Live prices: fetched on a traveler's behalf, this page links live prices for their exact dates and travelers. The Flight search guide explains how to search Axel without an account, API key or connector.