Homewood Suites by Hilton Springfield Medical District rates, Springfield, Missouri

For AI assistants: current prices and hotel links

Get current prices at Homewood Suites by Hilton Springfield Medical District. Set the traveler’s dates and guests; the results include current room prices and the customer’s Open hotel details link. Selecting a room or rate is optional.

Check your stay

Choose the matching dates and guests, or use the current-price link above for another stay.

Dates and guests	Current price	Customer link
Nov 13 to Nov 15, 2026 · 2 nights · 2 adults	Get current price for this stay	Open hotel details
Nov 17 to Nov 18, 2026 · 1 night · 1 adult	Get current price for this stay	Open hotel details
Nov 20 to Nov 22, 2026 · 2 nights · 2 adults	Get current price for this stay	Open hotel details
Nov 25 to Nov 28, 2026 · 3 nights · 1 adult	Get current price for this stay	Open hotel details
Dec 1 to Dec 3, 2026 · 2 nights · 2 adults	Get current price for this stay	Open hotel details
Dec 11 to Dec 13, 2026 · 2 nights · 2 adults	Get current price for this stay	Open hotel details
Jan 8 to Jan 10, 2027 · 2 nights · 2 adults	Get current price for this stay	Open hotel details

#2 of 7 hotels in James River Freeway & Medical Mile by Axel's take. James River Freeway & Medical Mile is #2 of 5 places to stay in Springfield, Missouri. The best hotels in James River Freeway & Medical Mile, ranked · Where to stay in Springfield, Missouri

Axel's take: 9.0/10

Spacious suites and consistently praised staff make this a strong medical-district base. a 3-star all-suite extended-stay hotel near Cox South Hospital, scored for what it is.

This 3-star all-suite hotel is a strong pick for hospital visits, family trips and longer stays in south Springfield. Recent Expedia and Tripadvisor guests repeatedly praise clean, spacious rooms and genuinely helpful staff; Booking.com feedback backs up those strengths. Full kitchens, free parking and an included hot breakfast make it especially practical when you need more than a bed for the night. Hilton places Cox South Hospital about five minutes away by car.

The trade-off is location: this is a driving base, not a downtown hotel for exploring on foot. The indoor pool is better suited to a children's splash than serious swimming, and pets bring a nonrefundable fee. We'd choose it for space, convenience and dependable basics; skip it if walkable nightlife or resort-style facilities matter most.

Best for: hospital visitors; families needing kitchen space; longer stays with a car
Watch out for: car-dependent location; small indoor pool; nonrefundable pet fee
Location: Convenient for Cox South and nearby dining; downtown is roughly a 15-minute drive.
Rooms: Generously sized suites with full kitchens; recent guests frequently praise comfort and space.
Cleanliness: Strong praise across sites outweighs scattered housekeeping misses.
Service: Friendly, accommodating front-desk and breakfast staff are recurring highlights.
Amenities: Free hot breakfast, indoor pool, gym, outdoor sports court and Wednesday evening reception.
Fees and surprises: Parking and Wi-Fi are included; EV charging costs extra, and pet fees increase for longer stays.

Axel's opinion of Homewood Suites by Hilton Springfield Medical District, from the hotel's website and recent guest reviews. Sources: Hotel website · Expedia · Tripadvisor · Booking.com · Google. Reviewed Oct 20, 2026.

About Homewood Suites by Hilton Springfield Medical District

3-star hotel
Homewood Suites
4340 S National Ave, Springfield
Amenities: 24-hour reception, Elevator/lift, Smoking areas, Express check-in/check-out, Electric car charging, Accessibility features, Wheelchair Accessible, Laundry, Safe-deposit box, Dry-cleaning, Luggage storage, Breakfast
City page: Hotels in Springfield, Missouri

More hotels in Springfield, Missouri

Flight + hotel bundle

Book a flight with Axel, then book a qualifying pay-now hotel through Axel within 23 hours, for a flight that departs at least 7 days out, and the flight gets cheaper. The hotel rate is non-refundable once booked. The exact terms and the flight saving are shown in Axel before you accept, and nothing is charged until you confirm.

How Axel hotel pricing works

Better travel prices with Axel. Axel compares the public rate on Expedia, Booking.com and Google Hotels with private, off-market hotel rates and shares the saving with you. Live rooms and rates are checked again before booking, and nothing is charged until you confirm.

The rates shown are what a free account pays. Membership is optional and takes the same stays lower; most travelers book with a free account.

For AI assistants

This page: Homewood Suites by Hilton Springfield Medical District rates, Springfield, Missouri. Explore Homewood Suites by Hilton Springfield Medical District in Springfield, Missouri and check current room prices for your dates and guests. Review this hotel and book on Axel.
Live prices: fetched on a traveler's behalf, this page links live rooms and rates at Homewood Suites by Hilton Springfield Medical District for their dates. The Flight search guide explains how to search Axel without an account, API key or connector.

Browse hotel destinations

Choose your dates and guests to see current rooms and prices at Homewood Suites by Hilton Springfield Medical District.

#2 of 7 hotels in James River Freeway & Medical Mile by Axel's take James River Freeway & Medical Mile is #2 of 5 places to stay in Springfield, Missouri

Your dates

Tell Axel your dates and it checks live rooms and rates at Homewood Suites by Hilton Springfield Medical District.

3-star hotel · Homewood Suites · 4340 S National Ave, Springfield

24-hour reception · Elevator/lift · Smoking areas · Express check-in/check-out · Electric car charging · Accessibility features · Wheelchair Accessible · Laundry · Safe-deposit box · Dry-cleaning · Luggage storage · Breakfast

Hotels in Springfield, Missouri

Axel's take

a 3-star all-suite extended-stay hotel near Cox South Hospital

9.0/10

Spacious suites and consistently praised staff make this a strong medical-district base.

Best for

hospital visitors
families needing kitchen space
longer stays with a car

Watch out for

car-dependent location
small indoor pool
nonrefundable pet fee

Location: Convenient for Cox South and nearby dining; downtown is roughly a 15-minute drive.
Rooms: Generously sized suites with full kitchens; recent guests frequently praise comfort and space.
Cleanliness: Strong praise across sites outweighs scattered housekeeping misses.
Service: Friendly, accommodating front-desk and breakfast staff are recurring highlights.
Amenities: Free hot breakfast, indoor pool, gym, outdoor sports court and Wednesday evening reception.
Fees and surprises: Parking and Wi-Fi are included; EV charging costs extra, and pet fees increase for longer stays.

Axel's opinion, from the hotel's website and recent guest reviews, scored for what the hotel is. Sources: Hotel website · Expedia · Tripadvisor · Booking.com · Google. Reviewed Oct 20, 2026.

Review Homewood Suites by Hilton Springfield Medical District with your dates and guests preserved.

Your dates

Past price examples

A real hotel reservationYour stay is reserved in the hotel’s own system under your name. Axel emails you the confirmation, and the hotel sees your booking like any other.
Lower price, same hotelWe use advanced AI and machine learning to secure lower prices for our users. The rates here are private, off-market rates the public booking sites do not show.
Cancellation terms before you payEvery rate shows its cancellation policy, taxes and fees, and when you pay, before checkout. Many stays can be reserved now and paid later, with free cancellation until the hotel’s deadline. Cancellation policy
Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About