Flights from San Diego to Spain in September

Flights for your trip

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

2026-11-20 · one way · $484.50

• American Airlines AA2343 / AA126: SAN 2026-11-20 10:14:00 → MAD 2026-11-21 09:25:00; 1 stop(s) via ORD; 851 minutes. Local airport times.
  • AA2343: SAN 2026-11-20 10:14:00 → ORD 2026-11-20 16:29:00; layover at ORD: 96 minutes.
  • AA126: ORD 2026-11-20 18:05:00 → MAD 2026-11-21 09:25:00.

2026-11-20 · one way · $503.50

• Alaska Airlines AS1494 / AA126: SAN 2026-11-20 10:29:00 → MAD 2026-11-21 09:25:00; 1 stop(s) via ORD; 836 minutes. Local airport times.
  • AS1494: SAN 2026-11-20 10:29:00 → ORD 2026-11-20 16:47:00; layover at ORD: 78 minutes.
  • AA126: ORD 2026-11-20 18:05:00 → MAD 2026-11-21 09:25:00.

2026-11-20 · one way · $513.00

• Delta Air Lines DL725 / DL108: SAN 2026-11-20 10:59:00 → MAD 2026-11-21 09:45:00; 1 stop(s) via ATL; 826 minutes. Local airport times.
  • DL725: SAN 2026-11-20 10:59:00 → ATL 2026-11-20 18:13:00; layover at ATL: 87 minutes.
  • DL108: ATL 2026-11-20 19:40:00 → MAD 2026-11-21 09:45:00.

2026-11-20 → 2026-11-23 · $745.75

• Alaska Airlines AS1494 / AA126: SAN 2026-11-20 10:29:00 → MAD 2026-11-21 09:25:00; 1 stop(s) via ORD; 836 minutes. Local airport times.
  • AS1494: SAN 2026-11-20 10:29:00 → ORD 2026-11-20 16:47:00; layover at ORD: 78 minutes.
  • AA126: ORD 2026-11-20 18:05:00 → MAD 2026-11-21 09:25:00.
• Iberia IB715 / BA273: MAD 2026-11-23 09:00:00 → SAN 2026-11-23 16:10:00; 1 stop(s) via LHR; 970 minutes. Local airport times.
  • IB715: MAD 2026-11-23 09:00:00 → LHR 2026-11-23 10:35:00; layover at LHR: 130 minutes.
  • BA273: LHR 2026-11-23 12:45:00 → SAN 2026-11-23 16:10:00.

2026-11-20 → 2026-11-23 · $750.50

• American Airlines AA1071 / AA748: SAN 2026-11-20 07:00:00 → MAD 2026-11-21 05:45:00; 1 stop(s) via CLT; 825 minutes. Local airport times.
  • AA1071: SAN 2026-11-20 07:00:00 → CLT 2026-11-20 14:47:00; layover at CLT: 78 minutes.
  • AA748: CLT 2026-11-20 16:05:00 → MAD 2026-11-21 05:45:00.
• American Airlines AA749 / AA3293: MAD 2026-11-23 12:40:00 → SAN 2026-11-23 20:48:00; 1 stop(s) via CLT; 1028 minutes. Local airport times.
  • AA749: MAD 2026-11-23 12:40:00 → CLT 2026-11-23 16:00:00; layover at CLT: 153 minutes.
  • AA3293: CLT 2026-11-23 18:33:00 → SAN 2026-11-23 20:48:00.

2026-11-20 → 2026-11-23 · $788.50

• Delta Air Lines DL725 / DL108: SAN 2026-11-20 10:59:00 → MAD 2026-11-21 09:45:00; 1 stop(s) via ATL; 826 minutes. Local airport times.
  • DL725: SAN 2026-11-20 10:59:00 → ATL 2026-11-20 18:13:00; layover at ATL: 87 minutes.
  • DL108: ATL 2026-11-20 19:40:00 → MAD 2026-11-21 09:45:00.
• Delta Air Lines DL95 / DL924: MAD 2026-11-23 10:40:00 → SAN 2026-11-23 18:47:00; 1 stop(s) via ATL; 1027 minutes. Local airport times.
  • DL95: MAD 2026-11-23 10:40:00 → ATL 2026-11-23 14:52:00; layover at ATL: 127 minutes.
  • DL924: ATL 2026-11-23 16:59:00 → SAN 2026-11-23 18:47:00.

2026-11-27 → 2026-12-04 · $754.50

• Alaska Airlines AS24 / IB212: SAN 2026-11-27 07:00:00 → MAD 2026-11-28 06:20:00; 1 stop(s) via JFK; 860 minutes. Local airport times.
  • AS24: SAN 2026-11-27 07:00:00 → JFK 2026-11-27 15:27:00; layover at JFK: 98 minutes.
  • IB212: JFK 2026-11-27 17:05:00 → MAD 2026-11-28 06:20:00.
• UX UX91 / DL685: MAD 2026-12-04 15:35:00 → SAN 2026-12-04 23:57:00; 1 stop(s) via JFK; 1042 minutes. Local airport times.
  • UX91: MAD 2026-12-04 15:35:00 → JFK 2026-12-04 17:50:00; layover at JFK: 171 minutes.
  • DL685: JFK 2026-12-04 20:41:00 → SAN 2026-12-04 23:57:00.

2026-11-20 · one way · $484.50

• American Airlines AA1071 / AA748: SAN 2026-11-20 07:00:00 → MAD 2026-11-21 05:45:00; 1 stop(s) via CLT; 825 minutes. Local airport times.
  • AA1071: SAN 2026-11-20 07:00:00 → CLT 2026-11-20 14:47:00; layover at CLT: 78 minutes.
  • AA748: CLT 2026-11-20 16:05:00 → MAD 2026-11-21 05:45:00.

2026-11-20 · one way · $503.50

• Alaska Airlines AS24 / IB212: SAN 2026-11-20 07:00:00 → MAD 2026-11-21 06:20:00; 1 stop(s) via JFK; 860 minutes. Local airport times.
  • AS24: SAN 2026-11-20 07:00:00 → JFK 2026-11-20 15:27:00; layover at JFK: 98 minutes.
  • IB212: JFK 2026-11-20 17:05:00 → MAD 2026-11-21 06:20:00.

2026-11-20 · one way · $503.50

• Alaska Airlines AS400 / AA36: SAN 2026-11-20 09:28:00 → MAD 2026-11-21 08:05:00; 1 stop(s) via DFW; 817 minutes. Local airport times.
  • AS400: SAN 2026-11-20 09:28:00 → DFW 2026-11-20 14:31:00; layover at DFW: 79 minutes.
  • AA36: DFW 2026-11-20 15:50:00 → MAD 2026-11-21 08:05:00.

2026-11-20 → 2026-11-23 · $745.75

• Alaska Airlines AS24 / IB212: SAN 2026-11-20 07:00:00 → MAD 2026-11-21 06:20:00; 1 stop(s) via JFK; 860 minutes. Local airport times.
  • AS24: SAN 2026-11-20 07:00:00 → JFK 2026-11-20 15:27:00; layover at JFK: 98 minutes.
  • IB212: JFK 2026-11-20 17:05:00 → MAD 2026-11-21 06:20:00.
• Iberia IB715 / BA273: MAD 2026-11-23 09:00:00 → SAN 2026-11-23 16:10:00; 1 stop(s) via LHR; 970 minutes. Local airport times.
  • IB715: MAD 2026-11-23 09:00:00 → LHR 2026-11-23 10:35:00; layover at LHR: 130 minutes.
  • BA273: LHR 2026-11-23 12:45:00 → SAN 2026-11-23 16:10:00.

2026-11-20 → 2026-11-23 · $745.75

• Alaska Airlines AS400 / AA36: SAN 2026-11-20 09:28:00 → MAD 2026-11-21 08:05:00; 1 stop(s) via DFW; 817 minutes. Local airport times.
  • AS400: SAN 2026-11-20 09:28:00 → DFW 2026-11-20 14:31:00; layover at DFW: 79 minutes.
  • AA36: DFW 2026-11-20 15:50:00 → MAD 2026-11-21 08:05:00.
• Iberia IB715 / BA273: MAD 2026-11-23 09:00:00 → SAN 2026-11-23 16:10:00; 1 stop(s) via LHR; 970 minutes. Local airport times.
  • IB715: MAD 2026-11-23 09:00:00 → LHR 2026-11-23 10:35:00; layover at LHR: 130 minutes.
  • BA273: LHR 2026-11-23 12:45:00 → SAN 2026-11-23 16:10:00.

2026-11-20 → 2026-11-23 · $750.50

• American Airlines AA2343 / AA126: SAN 2026-11-20 10:14:00 → MAD 2026-11-21 09:25:00; 1 stop(s) via ORD; 851 minutes. Local airport times.
  • AA2343: SAN 2026-11-20 10:14:00 → ORD 2026-11-20 16:29:00; layover at ORD: 96 minutes.
  • AA126: ORD 2026-11-20 18:05:00 → MAD 2026-11-21 09:25:00.
• American Airlines AA749 / AA3293: MAD 2026-11-23 12:40:00 → SAN 2026-11-23 20:48:00; 1 stop(s) via CLT; 1028 minutes. Local airport times.
  • AA749: MAD 2026-11-23 12:40:00 → CLT 2026-11-23 16:00:00; layover at CLT: 153 minutes.
  • AA3293: CLT 2026-11-23 18:33:00 → SAN 2026-11-23 20:48:00.

2026-11-27 → 2026-12-04 · $754.50

• Alaska Airlines AS1494 / AA126: SAN 2026-11-27 10:29:00 → MAD 2026-11-28 09:25:00; 1 stop(s) via ORD; 836 minutes. Local airport times.
  • AS1494: SAN 2026-11-27 10:29:00 → ORD 2026-11-27 16:47:00; layover at ORD: 78 minutes.
  • AA126: ORD 2026-11-27 18:05:00 → MAD 2026-11-28 09:25:00.
• UX UX91 / DL685: MAD 2026-12-04 15:35:00 → SAN 2026-12-04 23:57:00; 1 stop(s) via JFK; 1042 minutes. Local airport times.
  • UX91: MAD 2026-12-04 15:35:00 → JFK 2026-12-04 17:50:00; layover at JFK: 171 minutes.
  • DL685: JFK 2026-12-04 20:41:00 → SAN 2026-12-04 23:57:00.

2026-11-27 → 2026-12-04 · $754.50

• Alaska Airlines AS400 / AA36: SAN 2026-11-27 09:28:00 → MAD 2026-11-28 08:05:00; 1 stop(s) via DFW; 817 minutes. Local airport times.
  • AS400: SAN 2026-11-27 09:28:00 → DFW 2026-11-27 14:31:00; layover at DFW: 79 minutes.
  • AA36: DFW 2026-11-27 15:50:00 → MAD 2026-11-28 08:05:00.
• UX UX91 / DL685: MAD 2026-12-04 15:35:00 → SAN 2026-12-04 23:57:00; 1 stop(s) via JFK; 1042 minutes. Local airport times.
  • UX91: MAD 2026-12-04 15:35:00 → JFK 2026-12-04 17:50:00; layover at JFK: 171 minutes.
  • DL685: JFK 2026-12-04 20:41:00 → SAN 2026-12-04 23:57:00.

2026-11-27 → 2026-12-04 · $770.25

• American Airlines AA2343 / AA126: SAN 2026-11-27 10:14:00 → MAD 2026-11-28 09:25:00; 1 stop(s) via ORD; 851 minutes. Local airport times.
  • AA2343: SAN 2026-11-27 10:14:00 → ORD 2026-11-27 16:29:00; layover at ORD: 96 minutes.
  • AA126: ORD 2026-11-27 18:05:00 → MAD 2026-11-28 09:25:00.
• American Airlines AA749 / AA3293: MAD 2026-12-04 12:40:00 → SAN 2026-12-04 20:48:00; 1 stop(s) via CLT; 1028 minutes. Local airport times.
  • AA749: MAD 2026-12-04 12:40:00 → CLT 2026-12-04 16:00:00; layover at CLT: 153 minutes.
  • AA3293: CLT 2026-12-04 18:33:00 → SAN 2026-12-04 20:48:00.

2026-11-27 → 2026-12-04 · $770.25

• American Airlines AA1071 / AA748: SAN 2026-11-27 07:00:00 → MAD 2026-11-28 05:45:00; 1 stop(s) via CLT; 825 minutes. Local airport times.
  • AA1071: SAN 2026-11-27 07:00:00 → CLT 2026-11-27 14:47:00; layover at CLT: 78 minutes.
  • AA748: CLT 2026-11-27 16:05:00 → MAD 2026-11-28 05:45:00.
• American Airlines AA749 / AA3293: MAD 2026-12-04 12:40:00 → SAN 2026-12-04 20:48:00; 1 stop(s) via CLT; 1028 minutes. Local airport times.
  • AA749: MAD 2026-12-04 12:40:00 → CLT 2026-12-04 16:00:00; layover at CLT: 153 minutes.
  • AA3293: CLT 2026-12-04 18:33:00 → SAN 2026-12-04 20:48:00.

2026-11-27 → 2026-12-04 · $809.25

• Delta Air Lines DL725 / DL108: SAN 2026-11-27 10:59:00 → MAD 2026-11-28 09:45:00; 1 stop(s) via ATL; 826 minutes. Local airport times.
  • DL725: SAN 2026-11-27 10:59:00 → ATL 2026-11-27 18:13:00; layover at ATL: 87 minutes.
  • DL108: ATL 2026-11-27 19:40:00 → MAD 2026-11-28 09:45:00.
• Delta Air Lines DL95 / DL924: MAD 2026-12-04 10:40:00 → SAN 2026-12-04 18:47:00; 1 stop(s) via ATL; 1027 minutes. Local airport times.
  • DL95: MAD 2026-12-04 10:40:00 → ATL 2026-12-04 14:52:00; layover at ATL: 127 minutes.
  • DL924: ATL 2026-12-04 16:59:00 → SAN 2026-12-04 18:47:00.

More dates for this route

• Nov 20, 2026 → Nov 23, 2026
• Nov 27, 2026 → Dec 4, 2026
• Nov 20, 2026 · One way

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Spain in September from other cities

Fares observed October 28, 2026. USD for the travelers shown. Search a trip for current prices.

The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.

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Hotels in Madrid with Axel

Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in Madrid has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.

Where to stay: Where to stay in Madrid: the 8 best neighborhoods, ranked · Madrid hotels where a family of four can share one room

Hotels with an Axel review in Madrid: Hostal San Lorenzo · Hotel Eurostars Central · NeoMagna Madrid · Hostal Antón Martín · Petit Palace Tres Cruces · All 202 reviewed hotels in Madrid

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• This page: Flights from San Diego to Spain in September. Round-trip fares from San Diego to Spain in September: Madrid, Barcelona, Malaga, Palma de Mallorca, Sevilla and Valencia and more. Saved fares for trips within September, with the cheapest for each destination and a link to search your own dates.
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