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San Francisco → Panama City

Dec 12, 2026 · return Dec 22, 2026

SFO → PTY1 adulteconomyRound trip

8 flight options · 4 airlines

Nonstop flights

Sat, Dec 12 – Tue, Dec 22

Copa Airlines
7:36 pmSFO
7h 9m
Nonstop
5:45 am+1PTY
Copa Airlines
12:44 pmPTY
7h 41m
Nonstop
5:25 pmSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

Copa Airlines
12:33 amSFO
7h 13m
Nonstop
10:46 amPTY
Copa Airlines
12:44 pmPTY
7h 41m
Nonstop
5:25 pmSFO

Round-trip total · 1 adult · Taxes included

One-stop flights

Sat, Dec 12 – Tue, Dec 22

Avianca
1:15 pmSFO
9h 55m
SAL · 2h 15m
2:10 am+1PTY
Avianca
5:30 amPTY
9h 25m
SAL · 1h 15m
11:55 amSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

United Airlines
9:05 pmSFO
10h 9m
LAS · 2h 2m
10:14 am+1PTY
United Airlines
8:55 amPTY
11h 12m
IAH · 2h 30m
5:07 pmSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

American Airlines
12:37 amSFO
10h 4m
MIA · 1h 21m
1:41 pmPTY
Copa Airlines
12:44 pmPTY
7h 41m
Nonstop
5:25 pmSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

United Airlines
7:29 amSFO
9h 58m
MCO · 1h 16m
8:27 pmPTY
United Airlines
8:55 amPTY
11h 12m
IAH · 2h 30m
5:07 pmSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

United Airlines
7:15 amSFO
10h 4m
FLL · 1h 23m
8:19 pmPTY
United Airlines
8:55 amPTY
11h 12m
IAH · 2h 30m
5:07 pmSFO

Round-trip total · 1 adult · Taxes included

Sat, Dec 12 – Tue, Dec 22

United Airlines
9:22 pmSFO
9h 28m
LAX · 1h 23m
9:50 am+1PTY
United Airlines
8:55 amPTY
11h 12m
IAH · 2h 30m
5:07 pmSFO

Round-trip total · 1 adult · Taxes included

Make this trip yours

SFO ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Copa Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-12 → 2026-12-22Copa AirlinesCM409 / CM408$810.752026-10-29T02:07:07Z
2026-12-12 → 2026-12-22AviancaAV563 + AV317 / AV316 + AV562$622.752026-10-29T02:07:07Z
2026-12-12 → 2026-12-22United AirlinesUA406 + CM253 / UA1249 + UA589$787.252026-10-29T02:07:07Z
2026-12-12 → 2026-12-22American Airlines / Copa AirlinesAA1665 + AA315 / CM408$790.752026-10-29T02:07:07Z
2026-12-12 → 2026-12-22Copa AirlinesCM383 / CM408$810.752026-10-29T02:07:07Z
2026-12-12 → 2026-12-22United AirlinesUA1491 + CM445 / UA1249 + UA589$787.252026-10-29T02:07:07Z
2026-12-12 → 2026-12-22United AirlinesUA2722 + CM266 / UA1249 + UA589$787.252026-10-29T02:07:07Z
2026-12-12 → 2026-12-22United AirlinesUA2862 + CM473 / UA1249 + UA589$787.252026-10-29T02:07:07Z

2026-12-12 → 2026-12-22 · $810.75

  • Copa Airlines CM409: SFO 2026-12-12 19:36:00 → PTY 2026-12-13 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-22 12:44:00 → SFO 2026-12-22 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-12 → 2026-12-22 · $622.75

  • Avianca AV563 / AV317: SFO 2026-12-12 13:15:00 → PTY 2026-12-13 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-12 13:15:00 → SAL 2026-12-12 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-12 23:05:00 → PTY 2026-12-13 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-22 05:30:00 → SFO 2026-12-22 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-22 05:30:00 → SAL 2026-12-22 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-22 07:45:00 → SFO 2026-12-22 11:55:00.

2026-12-12 → 2026-12-22 · $787.25

  • United Airlines UA406 / CM253: SFO 2026-12-12 21:05:00 → PTY 2026-12-13 10:14:00; 1 stop(s) via LAS; 609 minutes. Local airport times.
    • UA406: SFO 2026-12-12 21:05:00 → LAS 2026-12-12 22:44:00; layover at LAS: 122 minutes.
    • CM253: LAS 2026-12-13 00:46:00 → PTY 2026-12-13 10:14:00.
  • United Airlines UA1249 / UA589: PTY 2026-12-22 08:55:00 → SFO 2026-12-22 17:07:00; 1 stop(s) via IAH; 672 minutes. Local airport times.
    • UA1249: PTY 2026-12-22 08:55:00 → IAH 2026-12-22 12:15:00; layover at IAH: 150 minutes.
    • UA589: IAH 2026-12-22 14:45:00 → SFO 2026-12-22 17:07:00.

2026-12-12 → 2026-12-22 · $790.75

  • American Airlines AA1665 / AA315: SFO 2026-12-12 00:37:00 → PTY 2026-12-12 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
    • AA1665: SFO 2026-12-12 00:37:00 → MIA 2026-12-12 09:06:00; layover at MIA: 81 minutes.
    • AA315: MIA 2026-12-12 10:27:00 → PTY 2026-12-12 13:41:00.
  • Copa Airlines CM408: PTY 2026-12-22 12:44:00 → SFO 2026-12-22 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-12 → 2026-12-22 · $810.75

  • Copa Airlines CM383: SFO 2026-12-12 00:33:00 → PTY 2026-12-12 10:46:00; nonstop; 433 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-22 12:44:00 → SFO 2026-12-22 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-12 → 2026-12-22 · $787.25

  • United Airlines UA1491 / CM445: SFO 2026-12-12 07:29:00 → PTY 2026-12-12 20:27:00; 1 stop(s) via MCO; 598 minutes. Local airport times.
    • UA1491: SFO 2026-12-12 07:29:00 → MCO 2026-12-12 15:43:00; layover at MCO: 76 minutes.
    • CM445: MCO 2026-12-12 16:59:00 → PTY 2026-12-12 20:27:00.
  • United Airlines UA1249 / UA589: PTY 2026-12-22 08:55:00 → SFO 2026-12-22 17:07:00; 1 stop(s) via IAH; 672 minutes. Local airport times.
    • UA1249: PTY 2026-12-22 08:55:00 → IAH 2026-12-22 12:15:00; layover at IAH: 150 minutes.
    • UA589: IAH 2026-12-22 14:45:00 → SFO 2026-12-22 17:07:00.

2026-12-12 → 2026-12-22 · $787.25

  • United Airlines UA2722 / CM266: SFO 2026-12-12 07:15:00 → PTY 2026-12-12 20:19:00; 1 stop(s) via FLL; 604 minutes. Local airport times.
    • UA2722: SFO 2026-12-12 07:15:00 → FLL 2026-12-12 15:45:00; layover at FLL: 83 minutes.
    • CM266: FLL 2026-12-12 17:08:00 → PTY 2026-12-12 20:19:00.
  • United Airlines UA1249 / UA589: PTY 2026-12-22 08:55:00 → SFO 2026-12-22 17:07:00; 1 stop(s) via IAH; 672 minutes. Local airport times.
    • UA1249: PTY 2026-12-22 08:55:00 → IAH 2026-12-22 12:15:00; layover at IAH: 150 minutes.
    • UA589: IAH 2026-12-22 14:45:00 → SFO 2026-12-22 17:07:00.

2026-12-12 → 2026-12-22 · $787.25

  • United Airlines UA2862 / CM473: SFO 2026-12-12 21:22:00 → PTY 2026-12-13 09:50:00; 1 stop(s) via LAX; 568 minutes. Local airport times.
    • UA2862: SFO 2026-12-12 21:22:00 → LAX 2026-12-12 22:52:00; layover at LAX: 83 minutes.
    • CM473: LAX 2026-12-13 00:15:00 → PTY 2026-12-13 09:50:00.
  • United Airlines UA1249 / UA589: PTY 2026-12-22 08:55:00 → SFO 2026-12-22 17:07:00; 1 stop(s) via IAH; 672 minutes. Local airport times.
    • UA1249: PTY 2026-12-22 08:55:00 → IAH 2026-12-22 12:15:00; layover at IAH: 150 minutes.
    • UA589: IAH 2026-12-22 14:45:00 → SFO 2026-12-22 17:07:00.

More dates for this route