Travel with Axel,
get the best price.

San Diego → Saint Louis

Dec 21, 2026 · return Dec 27, 2026

SAN → STL1 adulteconomyRound trip

6 flight options · 3 airlines

One-stop flights

Mon, Dec 21 – Sun, Dec 27

Southwest Airlines
5:20 pmSAN
5h 30m
DEN · 1h 10m
12:50 am+1STL
Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sun, Dec 27

United Airlines
8:40 amSAN
6h 17m
DEN · 1h 49m
4:57 pmSTL
Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sun, Dec 27

American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL
American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sun, Dec 27

Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL
Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sun, Dec 27

Southwest Airlines
3:40 pmSAN
6h 40m
PHX · 2h 25m
12:20 am+1STL
Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sun, Dec 27

Southwest Airlines
6:20 pmSAN
3h 25m
Nonstop
11:45 pmSTL
Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

Round-trip total · 1 adult · Taxes included

Make this trip yours

SAN ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2026-12-27Southwest AirlinesWN3701 + WN1845 / WN4249 + WN352$462.002026-10-29T01:10:51Z
2026-12-21 → 2026-12-27United Airlines / Southwest AirlinesUA2476 + UA1639 / WN4249 + WN352$483.002026-10-29T01:10:51Z
2026-12-21 → 2026-12-27American AirlinesAA2438 + AA2289 / AA2303 + AA2016$490.002026-10-29T01:10:51Z
2026-12-21 → 2026-12-27Southwest AirlinesWN2227 + WN1498 / WN4249 + WN352$462.002026-10-29T01:10:51Z
2026-12-21 → 2026-12-27Southwest AirlinesWN3727 + WN3528 / WN4249 + WN352$462.002026-10-29T01:10:51Z
2026-12-21 → 2026-12-27Southwest AirlinesWN3823 / WN4249 + WN352$490.002026-10-29T01:10:51Z

2026-12-21 → 2026-12-27 · $462.00

  • Southwest Airlines WN3701 / WN1845: SAN 2026-12-21 17:20:00 → STL 2026-12-22 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
    • WN3701: SAN 2026-12-21 17:20:00 → DEN 2026-12-21 20:40:00; layover at DEN: 70 minutes.
    • WN1845: DEN 2026-12-21 21:50:00 → STL 2026-12-22 00:50:00.
  • Southwest Airlines WN4249 / WN352: STL 2026-12-27 08:00:00 → SAN 2026-12-27 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-12-27 08:00:00 → LAS 2026-12-27 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-12-27 11:10:00 → SAN 2026-12-27 12:30:00.

2026-12-21 → 2026-12-27 · $483.00

  • United Airlines UA2476 / UA1639: SAN 2026-12-21 08:40:00 → STL 2026-12-21 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
    • UA2476: SAN 2026-12-21 08:40:00 → DEN 2026-12-21 12:06:00; layover at DEN: 109 minutes.
    • UA1639: DEN 2026-12-21 13:55:00 → STL 2026-12-21 16:57:00.
  • Southwest Airlines WN4249 / WN352: STL 2026-12-27 08:00:00 → SAN 2026-12-27 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-12-27 08:00:00 → LAS 2026-12-27 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-12-27 11:10:00 → SAN 2026-12-27 12:30:00.

2026-12-21 → 2026-12-27 · $490.00

  • American Airlines AA2438 / AA2289: SAN 2026-12-21 15:13:00 → STL 2026-12-21 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-12-21 15:13:00 → DFW 2026-12-21 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-12-21 21:45:00 → STL 2026-12-21 23:34:00.
  • American Airlines AA2303 / AA2016: STL 2026-12-27 14:23:00 → SAN 2026-12-27 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-12-27 14:23:00 → PHX 2026-12-27 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-12-27 18:05:00 → SAN 2026-12-27 18:24:00.

2026-12-21 → 2026-12-27 · $462.00

  • Southwest Airlines WN2227 / WN1498: SAN 2026-12-21 13:25:00 → STL 2026-12-21 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-12-21 13:25:00 → DAL 2026-12-21 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-12-21 19:20:00 → STL 2026-12-21 21:10:00.
  • Southwest Airlines WN4249 / WN352: STL 2026-12-27 08:00:00 → SAN 2026-12-27 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-12-27 08:00:00 → LAS 2026-12-27 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-12-27 11:10:00 → SAN 2026-12-27 12:30:00.

2026-12-21 → 2026-12-27 · $462.00

  • Southwest Airlines WN3727 / WN3528: SAN 2026-12-21 15:40:00 → STL 2026-12-22 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
    • WN3727: SAN 2026-12-21 15:40:00 → PHX 2026-12-21 18:00:00; layover at PHX: 145 minutes.
    • WN3528: PHX 2026-12-21 20:25:00 → STL 2026-12-22 00:20:00.
  • Southwest Airlines WN4249 / WN352: STL 2026-12-27 08:00:00 → SAN 2026-12-27 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-12-27 08:00:00 → LAS 2026-12-27 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-12-27 11:10:00 → SAN 2026-12-27 12:30:00.

2026-12-21 → 2026-12-27 · $490.00

  • Southwest Airlines WN3823: SAN 2026-12-21 18:20:00 → STL 2026-12-21 23:45:00; nonstop; 205 minutes. Local airport times.
  • Southwest Airlines WN4249 / WN352: STL 2026-12-27 08:00:00 → SAN 2026-12-27 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-12-27 08:00:00 → LAS 2026-12-27 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-12-27 11:10:00 → SAN 2026-12-27 12:30:00.

More dates for this route