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San Diego → Saint Louis

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SAN → STL1 adulteconomy

24 flight options · 3 airlines

Round-trip flights

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
6:20 pmSAN
3h 25m
Nonstop
11:45 pmSTL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
8:40 amSAN
6h 17m
DEN · 1h 49m
4:57 pmSTL
Frontier Airlines
7:58 pmSTL
6h
DEN · 1h
11:58 pmSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL
American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
6:20 pmSAN
3h 25m
Nonstop
11:45 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
3:40 pmSAN
6h 40m
PHX · 2h 25m
12:20 am+1STL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
5:20 pmSAN
5h 30m
DEN · 1h 10m
12:50 am+1STL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Show 8 more flights

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
9:15 amSAN
6h 5m
SAT · 1h 20m
5:20 pmSTL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL
Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
5:20 pmSAN
5h 30m
DEN · 1h 10m
12:50 am+1STL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
3:40 pmSAN
6h 40m
PHX · 2h 25m
12:20 am+1STL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
9:15 amSAN
6h 5m
SAT · 1h 20m
5:20 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL
American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
8:40 amSAN
6h 17m
DEN · 1h 49m
4:57 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Southwest Airlines
6:20 pmSAN
3h 25m
Nonstop
11:45 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
8:40 amSAN
6h 17m
DEN · 1h 49m
4:57 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
9:15 amSAN
6h 5m
SAT · 1h 20m
5:20 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
3:40 pmSAN
6h 40m
PHX · 2h 25m
12:20 am+1STL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
5:20 pmSAN
5h 30m
DEN · 1h 10m
12:50 am+1STL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

One-way total · 1 adult · Taxes included

Make this trip yours

SAN ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one waySouthwest AirlinesWN3823$263.252026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3823 / WN4452$434.752026-10-29T01:10:51Z
2026-11-20 · one wayAmerican AirlinesAA2438 + AA2289$249.752026-10-29T01:10:51Z
2026-11-20 · one wayUnited AirlinesUA2476 + UA1639$256.502026-10-29T01:10:51Z
2026-11-27 → 2026-12-04United Airlines / Frontier AirlinesUA2476 + UA1639 / F94567 + F92711$348.002026-10-29T01:10:51Z
2026-11-27 → 2026-12-04American AirlinesAA2438 + AA2289 / AA2303 + AA2016$411.252026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3823 / WN1733$499.502026-10-29T01:10:51Z
2026-11-20 · one waySouthwest AirlinesWN4711$263.252026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4711 / WN4452$434.752026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN4711 / WN1733$499.502026-10-29T01:10:51Z
2026-11-20 · one waySouthwest AirlinesWN2893 + WN3801$236.252026-10-29T01:10:51Z
2026-11-20 · one waySouthwest AirlinesWN3727 + WN3528$236.252026-10-29T01:10:51Z
2026-11-20 · one waySouthwest AirlinesWN3701 + WN1845$236.252026-10-29T01:10:51Z
2026-11-20 · one waySouthwest AirlinesWN2227 + WN1498$236.252026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3727 + WN3528 / WN4452$407.752026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3701 + WN1845 / WN4452$407.752026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN2893 + WN3801 / WN4452$407.752026-10-29T01:10:51Z
2026-11-27 → 2026-12-04Southwest AirlinesWN2227 + WN1498 / WN4452$407.752026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN2227 + WN1498 / WN1733$472.502026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3701 + WN1845 / WN1733$472.502026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3727 + WN3528 / WN1733$472.502026-10-29T01:10:51Z
2026-11-20 → 2026-11-23Southwest AirlinesWN2893 + WN3801 / WN1733$472.502026-10-29T01:10:51Z
2026-11-20 → 2026-11-23American AirlinesAA2438 + AA2289 / AA2303 + AA2016$472.502026-10-29T01:10:51Z
2026-11-20 → 2026-11-23United Airlines / Southwest AirlinesUA2476 + UA1639 / WN1733$492.752026-10-29T01:10:51Z

2026-11-20 · one way · $263.25

  • Southwest Airlines WN3823: SAN 2026-11-20 18:20:00 → STL 2026-11-20 23:45:00; nonstop; 205 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $434.75

  • Southwest Airlines WN3823: SAN 2026-11-27 18:20:00 → STL 2026-11-27 23:45:00; nonstop; 205 minutes. Local airport times.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-20 · one way · $249.75

  • American Airlines AA2438 / AA2289: SAN 2026-11-20 15:13:00 → STL 2026-11-20 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-11-20 15:13:00 → DFW 2026-11-20 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-11-20 21:45:00 → STL 2026-11-20 23:34:00.

2026-11-20 · one way · $256.50

  • United Airlines UA2476 / UA1639: SAN 2026-11-20 08:40:00 → STL 2026-11-20 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
    • UA2476: SAN 2026-11-20 08:40:00 → DEN 2026-11-20 12:06:00; layover at DEN: 109 minutes.
    • UA1639: DEN 2026-11-20 13:55:00 → STL 2026-11-20 16:57:00.

2026-11-27 → 2026-12-04 · $348.00

  • United Airlines UA2476 / UA1639: SAN 2026-11-27 08:40:00 → STL 2026-11-27 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
    • UA2476: SAN 2026-11-27 08:40:00 → DEN 2026-11-27 12:06:00; layover at DEN: 109 minutes.
    • UA1639: DEN 2026-11-27 13:55:00 → STL 2026-11-27 16:57:00.
  • Frontier Airlines F94567 / F92711: STL 2026-12-04 19:58:00 → SAN 2026-12-04 23:58:00; 1 stop(s) via DEN; 360 minutes. Local airport times.
    • F94567: STL 2026-12-04 19:58:00 → DEN 2026-12-04 21:29:00; layover at DEN: 60 minutes.
    • F92711: DEN 2026-12-04 22:29:00 → SAN 2026-12-04 23:58:00.

2026-11-27 → 2026-12-04 · $411.25

  • American Airlines AA2438 / AA2289: SAN 2026-11-27 15:13:00 → STL 2026-11-27 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-11-27 15:13:00 → DFW 2026-11-27 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-11-27 21:45:00 → STL 2026-11-27 23:34:00.
  • American Airlines AA2303 / AA2016: STL 2026-12-04 14:23:00 → SAN 2026-12-04 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-12-04 14:23:00 → PHX 2026-12-04 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-12-04 18:05:00 → SAN 2026-12-04 18:24:00.

2026-11-20 → 2026-11-23 · $499.50

  • Southwest Airlines WN3823: SAN 2026-11-20 18:20:00 → STL 2026-11-20 23:45:00; nonstop; 205 minutes. Local airport times.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 · one way · $263.25

  • Southwest Airlines WN4711: SAN 2026-11-20 11:55:00 → STL 2026-11-20 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $434.75

  • Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $499.50

  • Southwest Airlines WN4711: SAN 2026-11-20 11:55:00 → STL 2026-11-20 17:25:00; nonstop; 210 minutes. Local airport times.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 · one way · $236.25

  • Southwest Airlines WN2893 / WN3801: SAN 2026-11-20 09:15:00 → STL 2026-11-20 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
    • WN2893: SAN 2026-11-20 09:15:00 → SAT 2026-11-20 14:00:00; layover at SAT: 80 minutes.
    • WN3801: SAT 2026-11-20 15:20:00 → STL 2026-11-20 17:20:00.

2026-11-20 · one way · $236.25

  • Southwest Airlines WN3727 / WN3528: SAN 2026-11-20 15:40:00 → STL 2026-11-21 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
    • WN3727: SAN 2026-11-20 15:40:00 → PHX 2026-11-20 18:00:00; layover at PHX: 145 minutes.
    • WN3528: PHX 2026-11-20 20:25:00 → STL 2026-11-21 00:20:00.

2026-11-20 · one way · $236.25

  • Southwest Airlines WN3701 / WN1845: SAN 2026-11-20 17:20:00 → STL 2026-11-21 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
    • WN3701: SAN 2026-11-20 17:20:00 → DEN 2026-11-20 20:40:00; layover at DEN: 70 minutes.
    • WN1845: DEN 2026-11-20 21:50:00 → STL 2026-11-21 00:50:00.

2026-11-20 · one way · $236.25

  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-20 13:25:00 → STL 2026-11-20 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-20 13:25:00 → DAL 2026-11-20 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-20 19:20:00 → STL 2026-11-20 21:10:00.

2026-11-27 → 2026-12-04 · $407.75

  • Southwest Airlines WN3727 / WN3528: SAN 2026-11-27 15:40:00 → STL 2026-11-28 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
    • WN3727: SAN 2026-11-27 15:40:00 → PHX 2026-11-27 18:00:00; layover at PHX: 145 minutes.
    • WN3528: PHX 2026-11-27 20:25:00 → STL 2026-11-28 00:20:00.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $407.75

  • Southwest Airlines WN3701 / WN1845: SAN 2026-11-27 17:20:00 → STL 2026-11-28 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
    • WN3701: SAN 2026-11-27 17:20:00 → DEN 2026-11-27 20:40:00; layover at DEN: 70 minutes.
    • WN1845: DEN 2026-11-27 21:50:00 → STL 2026-11-28 00:50:00.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $407.75

  • Southwest Airlines WN2893 / WN3801: SAN 2026-11-27 09:15:00 → STL 2026-11-27 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
    • WN2893: SAN 2026-11-27 09:15:00 → SAT 2026-11-27 14:00:00; layover at SAT: 80 minutes.
    • WN3801: SAT 2026-11-27 15:20:00 → STL 2026-11-27 17:20:00.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $407.75

  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-27 13:25:00 → STL 2026-11-27 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-27 13:25:00 → DAL 2026-11-27 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-27 19:20:00 → STL 2026-11-27 21:10:00.
  • Southwest Airlines WN4452: STL 2026-12-04 07:55:00 → SAN 2026-12-04 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $472.50

  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-20 13:25:00 → STL 2026-11-20 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-20 13:25:00 → DAL 2026-11-20 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-20 19:20:00 → STL 2026-11-20 21:10:00.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $472.50

  • Southwest Airlines WN3701 / WN1845: SAN 2026-11-20 17:20:00 → STL 2026-11-21 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
    • WN3701: SAN 2026-11-20 17:20:00 → DEN 2026-11-20 20:40:00; layover at DEN: 70 minutes.
    • WN1845: DEN 2026-11-20 21:50:00 → STL 2026-11-21 00:50:00.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $472.50

  • Southwest Airlines WN3727 / WN3528: SAN 2026-11-20 15:40:00 → STL 2026-11-21 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
    • WN3727: SAN 2026-11-20 15:40:00 → PHX 2026-11-20 18:00:00; layover at PHX: 145 minutes.
    • WN3528: PHX 2026-11-20 20:25:00 → STL 2026-11-21 00:20:00.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $472.50

  • Southwest Airlines WN2893 / WN3801: SAN 2026-11-20 09:15:00 → STL 2026-11-20 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
    • WN2893: SAN 2026-11-20 09:15:00 → SAT 2026-11-20 14:00:00; layover at SAT: 80 minutes.
    • WN3801: SAT 2026-11-20 15:20:00 → STL 2026-11-20 17:20:00.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $472.50

  • American Airlines AA2438 / AA2289: SAN 2026-11-20 15:13:00 → STL 2026-11-20 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-11-20 15:13:00 → DFW 2026-11-20 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-11-20 21:45:00 → STL 2026-11-20 23:34:00.
  • American Airlines AA2303 / AA2016: STL 2026-11-23 14:23:00 → SAN 2026-11-23 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-11-23 14:23:00 → PHX 2026-11-23 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-11-23 18:05:00 → SAN 2026-11-23 18:24:00.

2026-11-20 → 2026-11-23 · $492.75

  • United Airlines UA2476 / UA1639: SAN 2026-11-20 08:40:00 → STL 2026-11-20 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
    • UA2476: SAN 2026-11-20 08:40:00 → DEN 2026-11-20 12:06:00; layover at DEN: 109 minutes.
    • UA1639: DEN 2026-11-20 13:55:00 → STL 2026-11-20 16:57:00.
  • Southwest Airlines WN1733: STL 2026-11-23 08:25:00 → SAN 2026-11-23 10:20:00; nonstop; 235 minutes. Local airport times.

More dates for this route