Travel with Axel,
get the best price.

Detroit → Saint Louis

Dec 21, 2026 · return Jan 4, 2027

DTW → STL1 adulteconomyRound trip

7 flight options · 4 airlines

Nonstop flights

Mon, Dec 21 – Mon, Jan 4

Delta Air Lines
8:40 amDTW
1h 45m
Nonstop
9:25 amSTL
Delta Air Lines
6:40 amSTL
1h 33m
Nonstop
9:13 amDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

Delta Air Lines
4:42 pmDTW
1h 44m
Nonstop
5:26 pmSTL
Delta Air Lines
6:40 amSTL
1h 33m
Nonstop
9:13 amDTW

Round-trip total · 1 adult · Taxes included

One-stop flights

Mon, Dec 21 – Mon, Jan 4

Southwest Airlines
8:15 pmDTW
1h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

American Airlines
10:15 amDTW
6h 36m
ORD · 3h 34m
3:51 pmSTL
American Airlines
5:19 pmSTL
5h 34m
ORD · 2h 16m
11:53 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

United Airlines
2:00 pmDTW
6h 28m
ORD · 3h 11m
7:28 pmSTL
United Airlines
5:25 amSTL
7h 3m
ORD · 3h 49m
1:28 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

Southwest Airlines
8:50 amDTW
4h 50m
MDW · 2h 20m
12:40 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

Southwest Airlines
6:50 pmDTW
6h 5m
BNA · 3h
11:55 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Make this trip yours

DTW ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Delta Air Lines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2027-01-04Delta Air LinesDL2868 / DL1626$388.132026-10-29T01:11:33Z
2026-12-21 → 2027-01-04Southwest AirlinesWN4935 / WN665 + WN2971$314.382026-10-29T01:11:33Z
2026-12-21 → 2027-01-04American AirlinesAA3584 + AA1713 / AA6306 + AA3520$331.882026-10-29T01:11:33Z
2026-12-21 → 2027-01-04United AirlinesUA5381 + UA4412 / UA4439 + UA5756$343.132026-10-29T01:11:33Z
2026-12-21 → 2027-01-04Delta Air LinesDL2822 / DL1626$388.132026-10-29T01:11:33Z
2026-12-21 → 2027-01-04Southwest AirlinesWN1877 + WN2737 / WN665 + WN2971$320.632026-10-29T01:11:33Z
2026-12-21 → 2027-01-04Southwest AirlinesWN1754 + WN2043 / WN665 + WN2971$320.632026-10-29T01:11:33Z

2026-12-21 → 2027-01-04 · $388.13

  • Delta Air Lines DL2868: DTW 2026-12-21 08:40:00 → STL 2026-12-21 09:25:00; nonstop; 105 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2027-01-04 06:40:00 → DTW 2027-01-04 09:13:00; nonstop; 93 minutes. Local airport times.

2026-12-21 → 2027-01-04 · $314.38

  • Southwest Airlines WN4935: DTW 2026-12-21 20:15:00 → STL 2026-12-21 21:00:00; nonstop; 105 minutes. Local airport times.
  • Southwest Airlines WN665 / WN2971: STL 2027-01-04 10:35:00 → DTW 2027-01-04 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2027-01-04 10:35:00 → BNA 2027-01-04 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2027-01-04 15:20:00 → DTW 2027-01-04 18:00:00.

2026-12-21 → 2027-01-04 · $331.88

  • American Airlines AA3584 / AA1713: DTW 2026-12-21 10:15:00 → STL 2026-12-21 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-21 10:15:00 → ORD 2026-12-21 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-21 14:29:00 → STL 2026-12-21 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2027-01-04 17:19:00 → DTW 2027-01-04 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2027-01-04 17:19:00 → ORD 2027-01-04 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2027-01-04 21:15:00 → DTW 2027-01-04 23:53:00.

2026-12-21 → 2027-01-04 · $343.13

  • United Airlines UA5381 / UA4412: DTW 2026-12-21 14:00:00 → STL 2026-12-21 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
    • UA5381: DTW 2026-12-21 14:00:00 → ORD 2026-12-21 14:39:00; layover at ORD: 191 minutes.
    • UA4412: ORD 2026-12-21 17:50:00 → STL 2026-12-21 19:28:00.
  • United Airlines UA4439 / UA5756: STL 2027-01-04 05:25:00 → DTW 2027-01-04 13:28:00; 1 stop(s) via ORD; 423 minutes. Local airport times.
    • UA4439: STL 2027-01-04 05:25:00 → ORD 2027-01-04 06:58:00; layover at ORD: 229 minutes.
    • UA5756: ORD 2027-01-04 10:47:00 → DTW 2027-01-04 13:28:00.

2026-12-21 → 2027-01-04 · $388.13

  • Delta Air Lines DL2822: DTW 2026-12-21 16:42:00 → STL 2026-12-21 17:26:00; nonstop; 104 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2027-01-04 06:40:00 → DTW 2027-01-04 09:13:00; nonstop; 93 minutes. Local airport times.

2026-12-21 → 2027-01-04 · $320.63

  • Southwest Airlines WN1877 / WN2737: DTW 2026-12-21 08:50:00 → STL 2026-12-21 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
    • WN1877: DTW 2026-12-21 08:50:00 → MDW 2026-12-21 09:10:00; layover at MDW: 140 minutes.
    • WN2737: MDW 2026-12-21 11:30:00 → STL 2026-12-21 12:40:00.
  • Southwest Airlines WN665 / WN2971: STL 2027-01-04 10:35:00 → DTW 2027-01-04 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2027-01-04 10:35:00 → BNA 2027-01-04 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2027-01-04 15:20:00 → DTW 2027-01-04 18:00:00.

2026-12-21 → 2027-01-04 · $320.63

  • Southwest Airlines WN1754 / WN2043: DTW 2026-12-21 18:50:00 → STL 2026-12-21 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
    • WN1754: DTW 2026-12-21 18:50:00 → BNA 2026-12-21 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-12-21 22:40:00 → STL 2026-12-21 23:55:00.
  • Southwest Airlines WN665 / WN2971: STL 2027-01-04 10:35:00 → DTW 2027-01-04 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2027-01-04 10:35:00 → BNA 2027-01-04 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2027-01-04 15:20:00 → DTW 2027-01-04 18:00:00.

More dates for this route