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Detroit → Saint Louis

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DTW → STL1 adulteconomy

23 flight options · 4 airlines

Round-trip flights

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
8:15 pmDTW
1h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
3:04 pmDTW
1h 43m
Nonstop
3:47 pmSTL
Delta Air Lines
6:40 amSTL
1h 33m
Nonstop
9:13 amDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
10:15 amDTW
6h 36m
ORD · 3h 34m
3:51 pmSTL
American Airlines
5:19 pmSTL
5h 34m
ORD · 2h 16m
11:53 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
2:00 pmDTW
6h 28m
ORD · 3h 11m
7:28 pmSTL
United Airlines
5:25 amSTL
7h 3m
ORD · 3h 49m
1:28 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
6:55 amDTW
1h 50m
Nonstop
7:45 amSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
7:55 pmDTW
1h 42m
Nonstop
8:37 pmSTL
Delta Air Lines
6:40 amSTL
1h 33m
Nonstop
9:13 amDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
7:55 pmDTW
1h 42m
Nonstop
8:37 pmSTL
Delta Air Lines
10:14 amSTL
1h 32m
Nonstop
12:46 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
3:04 pmDTW
1h 43m
Nonstop
3:47 pmSTL
Delta Air Lines
10:14 amSTL
1h 32m
Nonstop
12:46 pmDTW

Round-trip total · 1 adult · Taxes included

Show 7 more flights

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
8:15 pmDTW
1h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
8:50 amDTW
4h 50m
MDW · 2h 20m
12:40 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
6:50 pmDTW
6h 5m
BNA · 3h
11:55 pmSTL
Southwest Airlines
10:35 amSTL
6h 25m
BNA · 3h 40m
6:00 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
8:50 amDTW
4h 50m
MDW · 2h 20m
12:40 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
6:50 pmDTW
6h 5m
BNA · 3h
11:55 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
10:15 amDTW
6h 36m
ORD · 3h 34m
3:51 pmSTL
American Airlines
5:19 pmSTL
5h 34m
ORD · 2h 16m
11:53 pmDTW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
2:00 pmDTW
6h 28m
ORD · 3h 11m
7:28 pmSTL
United Airlines
5:25 amSTL
7h 3m
ORD · 3h 49m
1:28 pmDTW

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Southwest Airlines
8:15 pmDTW
1h 45m
Nonstop
9:00 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
3:04 pmDTW
1h 43m
Nonstop
3:47 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
10:15 amDTW
6h 36m
ORD · 3h 34m
3:51 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
2:00 pmDTW
6h 28m
ORD · 3h 11m
7:28 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
6:55 amDTW
1h 50m
Nonstop
7:45 amSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
7:55 pmDTW
1h 42m
Nonstop
8:37 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
6:50 pmDTW
6h 5m
BNA · 3h
11:55 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
8:50 amDTW
4h 50m
MDW · 2h 20m
12:40 pmSTL

One-way total · 1 adult · Taxes included

Make this trip yours

DTW ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one waySouthwest AirlinesWN4935$145.002026-10-29T01:11:33Z
2026-11-20 · one wayDelta Air LinesDL1371$185.002026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4935 / WN1876$316.252026-10-29T01:11:33Z
2026-11-20 → 2026-11-23Delta Air LinesDL1371 / DL1626$345.002026-10-29T01:11:33Z
2026-11-20 · one wayAmerican AirlinesAA3584 + AA1713$155.002026-10-29T01:11:33Z
2026-11-20 · one wayUnited AirlinesUA5381 + UA4412$165.002026-10-29T01:11:33Z
2026-11-20 → 2026-11-23American AirlinesAA3584 + AA1713 / AA6306 + AA3520$295.002026-10-29T01:11:33Z
2026-11-20 → 2026-11-23United AirlinesUA5381 + UA4412 / UA4439 + UA5756$305.002026-10-29T01:11:33Z
2026-11-20 · one waySouthwest AirlinesWN1880$145.002026-10-29T01:11:33Z
2026-11-20 · one wayDelta Air LinesDL1541$185.002026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Southwest AirlinesWN1880 / WN1876$316.252026-10-29T01:11:33Z
2026-11-20 → 2026-11-23Delta Air LinesDL1541 / DL1626$345.002026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Delta Air LinesDL1541 / DL2868$396.752026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Delta Air LinesDL1371 / DL2868$396.752026-10-29T01:11:33Z
2026-11-20 · one waySouthwest AirlinesWN1754 + WN2043$155.002026-10-29T01:11:33Z
2026-11-20 · one waySouthwest AirlinesWN1877 + WN2737$155.002026-10-29T01:11:33Z
2026-11-20 → 2026-11-23Southwest AirlinesWN4935 / WN665 + WN2971$280.002026-10-29T01:11:33Z
2026-11-20 → 2026-11-23Southwest AirlinesWN1877 + WN2737 / WN665 + WN2971$285.002026-10-29T01:11:33Z
2026-11-20 → 2026-11-23Southwest AirlinesWN1754 + WN2043 / WN665 + WN2971$285.002026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Southwest AirlinesWN1877 + WN2737 / WN1876$322.752026-10-29T01:11:33Z
2026-11-27 → 2026-12-04Southwest AirlinesWN1754 + WN2043 / WN1876$322.752026-10-29T01:11:33Z
2026-11-27 → 2026-12-04American AirlinesAA3584 + AA1713 / AA6306 + AA3520$339.252026-10-29T01:11:33Z
2026-11-27 → 2026-12-04United AirlinesUA5381 + UA4412 / UA4439 + UA5756$350.752026-10-29T01:11:33Z

2026-11-20 · one way · $145.00

  • Southwest Airlines WN4935: DTW 2026-11-20 20:15:00 → STL 2026-11-20 21:00:00; nonstop; 105 minutes. Local airport times.

2026-11-20 · one way · $185.00

  • Delta Air Lines DL1371: DTW 2026-11-20 15:04:00 → STL 2026-11-20 15:47:00; nonstop; 103 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $316.25

  • Southwest Airlines WN4935: DTW 2026-11-27 20:15:00 → STL 2026-11-27 21:00:00; nonstop; 105 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-04 10:15:00 → DTW 2026-12-04 12:40:00; nonstop; 85 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $345.00

  • Delta Air Lines DL1371: DTW 2026-11-20 15:04:00 → STL 2026-11-20 15:47:00; nonstop; 103 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2026-11-23 06:40:00 → DTW 2026-11-23 09:13:00; nonstop; 93 minutes. Local airport times.

2026-11-20 · one way · $155.00

  • American Airlines AA3584 / AA1713: DTW 2026-11-20 10:15:00 → STL 2026-11-20 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-11-20 10:15:00 → ORD 2026-11-20 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-11-20 14:29:00 → STL 2026-11-20 15:51:00.

2026-11-20 · one way · $165.00

  • United Airlines UA5381 / UA4412: DTW 2026-11-20 14:00:00 → STL 2026-11-20 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
    • UA5381: DTW 2026-11-20 14:00:00 → ORD 2026-11-20 14:39:00; layover at ORD: 191 minutes.
    • UA4412: ORD 2026-11-20 17:50:00 → STL 2026-11-20 19:28:00.

2026-11-20 → 2026-11-23 · $295.00

  • American Airlines AA3584 / AA1713: DTW 2026-11-20 10:15:00 → STL 2026-11-20 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-11-20 10:15:00 → ORD 2026-11-20 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-11-20 14:29:00 → STL 2026-11-20 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-11-23 17:19:00 → DTW 2026-11-23 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-11-23 17:19:00 → ORD 2026-11-23 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-11-23 21:15:00 → DTW 2026-11-23 23:53:00.

2026-11-20 → 2026-11-23 · $305.00

  • United Airlines UA5381 / UA4412: DTW 2026-11-20 14:00:00 → STL 2026-11-20 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
    • UA5381: DTW 2026-11-20 14:00:00 → ORD 2026-11-20 14:39:00; layover at ORD: 191 minutes.
    • UA4412: ORD 2026-11-20 17:50:00 → STL 2026-11-20 19:28:00.
  • United Airlines UA4439 / UA5756: STL 2026-11-23 05:25:00 → DTW 2026-11-23 13:28:00; 1 stop(s) via ORD; 423 minutes. Local airport times.
    • UA4439: STL 2026-11-23 05:25:00 → ORD 2026-11-23 06:58:00; layover at ORD: 229 minutes.
    • UA5756: ORD 2026-11-23 10:47:00 → DTW 2026-11-23 13:28:00.

2026-11-20 · one way · $145.00

  • Southwest Airlines WN1880: DTW 2026-11-20 06:55:00 → STL 2026-11-20 07:45:00; nonstop; 110 minutes. Local airport times.

2026-11-20 · one way · $185.00

  • Delta Air Lines DL1541: DTW 2026-11-20 19:55:00 → STL 2026-11-20 20:37:00; nonstop; 102 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $316.25

  • Southwest Airlines WN1880: DTW 2026-11-27 06:55:00 → STL 2026-11-27 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-04 10:15:00 → DTW 2026-12-04 12:40:00; nonstop; 85 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $345.00

  • Delta Air Lines DL1541: DTW 2026-11-20 19:55:00 → STL 2026-11-20 20:37:00; nonstop; 102 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2026-11-23 06:40:00 → DTW 2026-11-23 09:13:00; nonstop; 93 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $396.75

  • Delta Air Lines DL1541: DTW 2026-11-27 19:55:00 → STL 2026-11-27 20:37:00; nonstop; 102 minutes. Local airport times.
  • Delta Air Lines DL2868: STL 2026-12-04 10:14:00 → DTW 2026-12-04 12:46:00; nonstop; 92 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $396.75

  • Delta Air Lines DL1371: DTW 2026-11-27 15:04:00 → STL 2026-11-27 15:47:00; nonstop; 103 minutes. Local airport times.
  • Delta Air Lines DL2868: STL 2026-12-04 10:14:00 → DTW 2026-12-04 12:46:00; nonstop; 92 minutes. Local airport times.

2026-11-20 · one way · $155.00

  • Southwest Airlines WN1754 / WN2043: DTW 2026-11-20 18:50:00 → STL 2026-11-20 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
    • WN1754: DTW 2026-11-20 18:50:00 → BNA 2026-11-20 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-11-20 22:40:00 → STL 2026-11-20 23:55:00.

2026-11-20 · one way · $155.00

  • Southwest Airlines WN1877 / WN2737: DTW 2026-11-20 08:50:00 → STL 2026-11-20 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
    • WN1877: DTW 2026-11-20 08:50:00 → MDW 2026-11-20 09:10:00; layover at MDW: 140 minutes.
    • WN2737: MDW 2026-11-20 11:30:00 → STL 2026-11-20 12:40:00.

2026-11-20 → 2026-11-23 · $280.00

  • Southwest Airlines WN4935: DTW 2026-11-20 20:15:00 → STL 2026-11-20 21:00:00; nonstop; 105 minutes. Local airport times.
  • Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

2026-11-20 → 2026-11-23 · $285.00

  • Southwest Airlines WN1877 / WN2737: DTW 2026-11-20 08:50:00 → STL 2026-11-20 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
    • WN1877: DTW 2026-11-20 08:50:00 → MDW 2026-11-20 09:10:00; layover at MDW: 140 minutes.
    • WN2737: MDW 2026-11-20 11:30:00 → STL 2026-11-20 12:40:00.
  • Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

2026-11-20 → 2026-11-23 · $285.00

  • Southwest Airlines WN1754 / WN2043: DTW 2026-11-20 18:50:00 → STL 2026-11-20 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
    • WN1754: DTW 2026-11-20 18:50:00 → BNA 2026-11-20 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-11-20 22:40:00 → STL 2026-11-20 23:55:00.
  • Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

2026-11-27 → 2026-12-04 · $322.75

  • Southwest Airlines WN1877 / WN2737: DTW 2026-11-27 08:50:00 → STL 2026-11-27 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
    • WN1877: DTW 2026-11-27 08:50:00 → MDW 2026-11-27 09:10:00; layover at MDW: 140 minutes.
    • WN2737: MDW 2026-11-27 11:30:00 → STL 2026-11-27 12:40:00.
  • Southwest Airlines WN1876: STL 2026-12-04 10:15:00 → DTW 2026-12-04 12:40:00; nonstop; 85 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $322.75

  • Southwest Airlines WN1754 / WN2043: DTW 2026-11-27 18:50:00 → STL 2026-11-27 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
    • WN1754: DTW 2026-11-27 18:50:00 → BNA 2026-11-27 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-11-27 22:40:00 → STL 2026-11-27 23:55:00.
  • Southwest Airlines WN1876: STL 2026-12-04 10:15:00 → DTW 2026-12-04 12:40:00; nonstop; 85 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $339.25

  • American Airlines AA3584 / AA1713: DTW 2026-11-27 10:15:00 → STL 2026-11-27 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-11-27 10:15:00 → ORD 2026-11-27 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-11-27 14:29:00 → STL 2026-11-27 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-04 17:19:00 → DTW 2026-12-04 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-04 17:19:00 → ORD 2026-12-04 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-04 21:15:00 → DTW 2026-12-04 23:53:00.

2026-11-27 → 2026-12-04 · $350.75

  • United Airlines UA5381 / UA4412: DTW 2026-11-27 14:00:00 → STL 2026-11-27 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
    • UA5381: DTW 2026-11-27 14:00:00 → ORD 2026-11-27 14:39:00; layover at ORD: 191 minutes.
    • UA4412: ORD 2026-11-27 17:50:00 → STL 2026-11-27 19:28:00.
  • United Airlines UA4439 / UA5756: STL 2026-12-04 05:25:00 → DTW 2026-12-04 13:28:00; 1 stop(s) via ORD; 423 minutes. Local airport times.
    • UA4439: STL 2026-12-04 05:25:00 → ORD 2026-12-04 06:58:00; layover at ORD: 229 minutes.
    • UA5756: ORD 2026-12-04 10:47:00 → DTW 2026-12-04 13:28:00.

More dates for this route