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Detroit → Saint Louis

Dec 21, 2026 · return Dec 25, 2026

DTW → STL1 adulteconomyRound trip

8 flight options · 4 airlines

Nonstop flights

Mon, Dec 21 – Fri, Dec 25

Southwest Airlines
8:15 pmDTW
1h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

Delta Air Lines
8:40 amDTW
1h 45m
Nonstop
9:25 amSTL
Delta Air Lines
10:14 amSTL
1h 32m
Nonstop
12:46 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

Southwest Airlines
6:55 amDTW
1h 50m
Nonstop
7:45 amSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

Delta Air Lines
4:42 pmDTW
1h 44m
Nonstop
5:26 pmSTL
Delta Air Lines
10:14 amSTL
1h 32m
Nonstop
12:46 pmDTW

Round-trip total · 1 adult · Taxes included

One-stop flights

Mon, Dec 21 – Fri, Dec 25

American Airlines
10:15 amDTW
6h 36m
ORD · 3h 34m
3:51 pmSTL
American Airlines
5:19 pmSTL
5h 34m
ORD · 2h 16m
11:53 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

United Airlines
2:00 pmDTW
6h 28m
ORD · 3h 11m
7:28 pmSTL
United Airlines
5:25 amSTL
7h 3m
ORD · 3h 49m
1:28 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

Southwest Airlines
8:50 amDTW
4h 50m
MDW · 2h 20m
12:40 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Fri, Dec 25

Southwest Airlines
6:50 pmDTW
6h 5m
BNA · 3h
11:55 pmSTL
Southwest Airlines
10:15 amSTL
1h 25m
Nonstop
12:40 pmDTW

Round-trip total · 1 adult · Taxes included

Make this trip yours

DTW ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2026-12-25Southwest AirlinesWN4935 / WN1876$343.762026-10-29T01:11:33Z
2026-12-21 → 2026-12-25Delta Air LinesDL2868 / DL2868$431.262026-10-29T01:11:33Z
2026-12-21 → 2026-12-25American AirlinesAA3584 + AA1713 / AA6306 + AA3520$368.762026-10-29T01:11:33Z
2026-12-21 → 2026-12-25United AirlinesUA5381 + UA4412 / UA4439 + UA5756$381.262026-10-29T01:11:33Z
2026-12-21 → 2026-12-25Southwest AirlinesWN1880 / WN1876$343.762026-10-29T01:11:33Z
2026-12-21 → 2026-12-25Delta Air LinesDL2822 / DL2868$431.262026-10-29T01:11:33Z
2026-12-21 → 2026-12-25Southwest AirlinesWN1877 + WN2737 / WN1876$350.012026-10-29T01:11:33Z
2026-12-21 → 2026-12-25Southwest AirlinesWN1754 + WN2043 / WN1876$350.012026-10-29T01:11:33Z

2026-12-21 → 2026-12-25 · $343.76

  • Southwest Airlines WN4935: DTW 2026-12-21 20:15:00 → STL 2026-12-21 21:00:00; nonstop; 105 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-25 10:15:00 → DTW 2026-12-25 12:40:00; nonstop; 85 minutes. Local airport times.

2026-12-21 → 2026-12-25 · $431.26

  • Delta Air Lines DL2868: DTW 2026-12-21 08:40:00 → STL 2026-12-21 09:25:00; nonstop; 105 minutes. Local airport times.
  • Delta Air Lines DL2868: STL 2026-12-25 10:14:00 → DTW 2026-12-25 12:46:00; nonstop; 92 minutes. Local airport times.

2026-12-21 → 2026-12-25 · $368.76

  • American Airlines AA3584 / AA1713: DTW 2026-12-21 10:15:00 → STL 2026-12-21 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-21 10:15:00 → ORD 2026-12-21 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-21 14:29:00 → STL 2026-12-21 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-25 17:19:00 → DTW 2026-12-25 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-25 17:19:00 → ORD 2026-12-25 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-25 21:15:00 → DTW 2026-12-25 23:53:00.

2026-12-21 → 2026-12-25 · $381.26

  • United Airlines UA5381 / UA4412: DTW 2026-12-21 14:00:00 → STL 2026-12-21 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
    • UA5381: DTW 2026-12-21 14:00:00 → ORD 2026-12-21 14:39:00; layover at ORD: 191 minutes.
    • UA4412: ORD 2026-12-21 17:50:00 → STL 2026-12-21 19:28:00.
  • United Airlines UA4439 / UA5756: STL 2026-12-25 05:25:00 → DTW 2026-12-25 13:28:00; 1 stop(s) via ORD; 423 minutes. Local airport times.
    • UA4439: STL 2026-12-25 05:25:00 → ORD 2026-12-25 06:58:00; layover at ORD: 229 minutes.
    • UA5756: ORD 2026-12-25 10:47:00 → DTW 2026-12-25 13:28:00.

2026-12-21 → 2026-12-25 · $343.76

  • Southwest Airlines WN1880: DTW 2026-12-21 06:55:00 → STL 2026-12-21 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-25 10:15:00 → DTW 2026-12-25 12:40:00; nonstop; 85 minutes. Local airport times.

2026-12-21 → 2026-12-25 · $431.26

  • Delta Air Lines DL2822: DTW 2026-12-21 16:42:00 → STL 2026-12-21 17:26:00; nonstop; 104 minutes. Local airport times.
  • Delta Air Lines DL2868: STL 2026-12-25 10:14:00 → DTW 2026-12-25 12:46:00; nonstop; 92 minutes. Local airport times.

2026-12-21 → 2026-12-25 · $350.01

  • Southwest Airlines WN1877 / WN2737: DTW 2026-12-21 08:50:00 → STL 2026-12-21 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
    • WN1877: DTW 2026-12-21 08:50:00 → MDW 2026-12-21 09:10:00; layover at MDW: 140 minutes.
    • WN2737: MDW 2026-12-21 11:30:00 → STL 2026-12-21 12:40:00.
  • Southwest Airlines WN1876: STL 2026-12-25 10:15:00 → DTW 2026-12-25 12:40:00; nonstop; 85 minutes. Local airport times.

2026-12-21 → 2026-12-25 · $350.01

  • Southwest Airlines WN1754 / WN2043: DTW 2026-12-21 18:50:00 → STL 2026-12-21 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
    • WN1754: DTW 2026-12-21 18:50:00 → BNA 2026-12-21 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-12-21 22:40:00 → STL 2026-12-21 23:55:00.
  • Southwest Airlines WN1876: STL 2026-12-25 10:15:00 → DTW 2026-12-25 12:40:00; nonstop; 85 minutes. Local airport times.

More dates for this route