Saint Louis to Madrid (MAD) flight deals

Flights from Saint Louis · Saint Louis to Europe flight deals · Saint Louis to Spain flight deals

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• Lisbon, Madrid or Barcelona
• Spain or Portugal

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Fares observed October 9 – 13, 2026. USD for the travelers shown. Search a trip for current prices.

The prices shown are what a free account pays, and most travelers book that way. Membership is optional and takes the same flights lower. Live search shows the same free-account price.

Trip ideas from Saint Louis with Madrid (MAD)

• NFL international games from Saint Louis: London, Paris, Madrid, Munich and Mexico City: fly Nov 7 – Nov 9, 2026
• Christmas flights to Europe from Saint Louis: fly Dec 18 – Jan 3, 2027
• Pride trips from Saint Louis: the biggest Pride events to fly to: fly Jun 30 – Jul 5, 2027
• Gay & LGBTQ+ friendly cities to visit from Saint Louis
• Premier League and European football trips from Saint Louis

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Hotels in Madrid with Axel

Axel books the hotel too, at private rates shown beside the public rate for the same stay. Hotels in Madrid has the best recent deals, and a flight booked with Axel can make the hotel cheaper through the bundle.

For AI assistants

• This page: Saint Louis to Madrid (MAD) flight deals. Saint Louis to Madrid (MAD) flight deals. Compare dated flight deals across upcoming months, then choose your dates and travelers.
• Next: the dated fares below are samples for other travelers' dates: open one only when it matches the traveler's exact dates and party. Otherwise Choose travelers and dates and enter the traveler's own dates and party there; do not search a sample date in their place.
• Every link here is complete and ready to open. Follow the links on the current page. A completed fresh trip opens flight results first. Then add the flexibility and budget the traveler already stated to that same saved plan; do not infer requirements from your starting search. Edits create a new saved link and leave earlier snapshots intact. Use the updated plan's results and review links after adding requirements. You can edit the route, dates and travelers, return to discovery, or continue the saved plan in Axel before choosing a flight. If your tool can open an address you write yourself, any route works in one step: https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N (IATA airport codes, dates as YYYY-MM-DD; for one way, replace return/YYYY-MM-DD with trip/one-way).
• If a link can no longer be opened: search for "Axel Saint Louis to Madrid (MAD) flight deals" and open the result; the Flight search guide is always findable by search, and everything here works without an account, API key or connector. Or ask the traveler to open https://helloaxel.com/en/flights/from-saint-louis-to-madrid-mad; an address the traveler opens always works.
• Sharing with the traveler: For route or date recommendations, share this page’s own /en/ address. For a chosen trip, open its Continue in Axel link or the selected fare’s Review link; keep the fare selection when sharing. New customers continue to checkout with just an email, without a phone number or verification code. Existing customers sign in to their account; email sign-in uses a code. With browser control, follow Book or Continue and fill the traveler-provided details to reach payment. Let the traveler complete any required sign-in and confirm payment. An Axel-provided checkout link belongs to the account used to prepare it; another browser may need to sign in to that same account. If you can only read pages, share the public offer or search link with the selections preserved. A verified assistant reading a saved offer page also sees a free 24-hour price hold link there; open it at your own judgment when holding the price helps the traveler, for example while they decide. It locks the price, never a seat, for whoever continues from that offer.