Travel with Axel, get the best price.

Route overview: Knoxville to Chicago (ORD) flight deals

Knoxville (TYS) to Chicago (ORD), Nov 9–12, 2026: from $300 round trip

Knoxville (TYS) to Chicago (ORD), Nov 9–12, 2026: from $300 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $300 round trip, Axel-exclusive, American Airlines, nonstop, Nov 9–12, 2026, 1 adult, economy, checked Oct 29, 2026.

TYS → ORD1 adulteconomyRound trip

7 flight options · 3 airlines

Nonstop flights

Mon, Nov 9 – Thu, Nov 12

American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD
American Airlines
4:00 pmORD
1h 46m
Nonstop
6:46 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Nov 9 – Thu, Nov 12

United Airlines
5:40 pmTYS
2h 3m
Nonstop
6:43 pmORD
United Airlines
5:59 pmORD
1h 55m
Nonstop
8:54 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Nov 9 – Thu, Nov 12

American Airlines
11:33 amTYS
2h 7m
Nonstop
12:40 pmORD
American Airlines
4:00 pmORD
1h 46m
Nonstop
6:46 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Nov 9 – Thu, Nov 12

United Airlines
6:45 amTYS
2h 9m
Nonstop
7:54 amORD
United Airlines
5:59 pmORD
1h 55m
Nonstop
8:54 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

One-stop flights

Mon, Nov 9 – Thu, Nov 12

Delta Air Lines
12:32 pmTYS
5h 34m
ATL · 2h 12m
5:06 pmORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Nov 9 – Thu, Nov 12

American Airlines
8:04 pmTYS
4h 55m
CLT · 1h 25m
11:59 pmORD
American Airlines
4:00 pmORD
1h 46m
Nonstop
6:46 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Nov 9 – Thu, Nov 12

Delta Air Lines
7:10 amTYS
4h 49m
DTW · 1h 20m
10:59 amORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Hotels for these nights (Nov 9–12, 2026 · 3 nights · 2 adults, 1 room): 3★ Hyatt Place Chicago/Wicker Park · 4★ LondonHouse Chicago, Curio Collection by Hilton · 5★ The Langham, Chicago

Make this trip yours

TYS ⇄ ORD

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, American Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

Explore this route

All dates for this routeNov 8, 2026 · Return optionsNov 10, 2026 · Return optionsHotels in Chicago with Axel
For AI assistants: every fare, every link, instructions

Knoxville (TYS) to Chicago (ORD), Nov 9–12, 2026: from $300 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $300 round trip, Axel-exclusive, American Airlines, nonstop, Nov 9–12, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-11-09 → 2026-11-12American AirlinesAA3653 / AA366120:52:00→21:58:00 2h 06m nonstop · 16:00:00→18:46:00 1h 46m nonstopAxel-exclusive $300.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12United AirlinesUA5478 / UA571917:40:00→18:43:00 2h 03m nonstop · 17:59:00→20:54:00 1h 55m nonstopAxel-exclusive $310.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12Delta Air LinesDL1743 + DL2738 / DL1477 + DL527212:32:00→17:06:00 5h 34m 1 stop via ATL · 15:59:00→21:56:00 4h 57m 1 stop via ATLAxel-exclusive $350.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12American AirlinesAA5408 / AA366111:33:00→12:40:00 2h 07m nonstop · 16:00:00→18:46:00 1h 46m nonstopAxel-exclusive $300.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12United AirlinesUA5524 / UA571906:45:00→07:54:00 2h 09m nonstop · 17:59:00→20:54:00 1h 55m nonstopAxel-exclusive $310.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12American AirlinesAA5675 + AA1039 / AA366120:04:00→23:59:00 4h 55m 1 stop via CLT · 16:00:00→18:46:00 1h 46m nonstopAxel-exclusive $315.002026-10-29T01:30:55Z
2026-11-09 → 2026-11-12Delta Air LinesDL5196 + DL3902 / DL1477 + DL527207:10:00→10:59:00 4h 49m 1 stop via DTW · 15:59:00→21:56:00 4h 57m 1 stop via ATLAxel-exclusive $350.002026-10-29T01:30:55Z

Hotels in Chicago for these trips

Hotels: under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in Chicago

Route overview: Knoxville to Chicago (ORD) flight deals

2026-11-09 → 2026-11-12 · Axel-exclusive $300.00

  • American Airlines AA3653: TYS 2026-11-09 20:52:00 → ORD 2026-11-09 21:58:00; nonstop; 126 minutes. Local airport times.
  • American Airlines AA3661: ORD 2026-11-12 16:00:00 → TYS 2026-11-12 18:46:00; nonstop; 106 minutes. Local airport times.

2026-11-09 → 2026-11-12 · Axel-exclusive $310.00

  • United Airlines UA5478: TYS 2026-11-09 17:40:00 → ORD 2026-11-09 18:43:00; nonstop; 123 minutes. Local airport times.
  • United Airlines UA5719: ORD 2026-11-12 17:59:00 → TYS 2026-11-12 20:54:00; nonstop; 115 minutes. Local airport times.

2026-11-09 → 2026-11-12 · Axel-exclusive $350.00

  • Delta Air Lines DL1743 / DL2738: TYS 2026-11-09 12:32:00 → ORD 2026-11-09 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
    • DL1743: TYS 2026-11-09 12:32:00 → ATL 2026-11-09 13:38:00; layover at ATL: 132 minutes.
    • DL2738: ATL 2026-11-09 15:50:00 → ORD 2026-11-09 17:06:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-11-12 15:59:00 → TYS 2026-11-12 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-11-12 15:59:00 → ATL 2026-11-12 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-11-12 20:52:00 → TYS 2026-11-12 21:56:00.

2026-11-09 → 2026-11-12 · Axel-exclusive $300.00

  • American Airlines AA5408: TYS 2026-11-09 11:33:00 → ORD 2026-11-09 12:40:00; nonstop; 127 minutes. Local airport times.
  • American Airlines AA3661: ORD 2026-11-12 16:00:00 → TYS 2026-11-12 18:46:00; nonstop; 106 minutes. Local airport times.

2026-11-09 → 2026-11-12 · Axel-exclusive $310.00

  • United Airlines UA5524: TYS 2026-11-09 06:45:00 → ORD 2026-11-09 07:54:00; nonstop; 129 minutes. Local airport times.
  • United Airlines UA5719: ORD 2026-11-12 17:59:00 → TYS 2026-11-12 20:54:00; nonstop; 115 minutes. Local airport times.

2026-11-09 → 2026-11-12 · Axel-exclusive $315.00

  • American Airlines AA5675 / AA1039: TYS 2026-11-09 20:04:00 → ORD 2026-11-09 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
    • AA5675: TYS 2026-11-09 20:04:00 → CLT 2026-11-09 21:28:00; layover at CLT: 85 minutes.
    • AA1039: CLT 2026-11-09 22:53:00 → ORD 2026-11-09 23:59:00.
  • American Airlines AA3661: ORD 2026-11-12 16:00:00 → TYS 2026-11-12 18:46:00; nonstop; 106 minutes. Local airport times.

2026-11-09 → 2026-11-12 · Axel-exclusive $350.00

  • Delta Air Lines DL5196 / DL3902: TYS 2026-11-09 07:10:00 → ORD 2026-11-09 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
    • DL5196: TYS 2026-11-09 07:10:00 → DTW 2026-11-09 09:00:00; layover at DTW: 80 minutes.
    • DL3902: DTW 2026-11-09 10:20:00 → ORD 2026-11-09 10:59:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-11-12 15:59:00 → TYS 2026-11-12 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-11-12 15:59:00 → ATL 2026-11-12 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-11-12 20:52:00 → TYS 2026-11-12 21:56:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

For AI assistants

  • This page: Knoxville (TYS) to Chicago (ORD) · Nov 9, 2026 · return Nov 12, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Knoxville to Chicago (ORD) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.