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Knoxville → Chicago

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TYS → ORD1 adulteconomy

20 flight options · 3 airlines

Round-trip flights

Fri, Nov 20 – Mon, Nov 23

United Airlines
10:57 amTYS
2h 2m
Nonstop
11:59 amORD
United Airlines
2:10 pmORD
1h 50m
Nonstop
5:00 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD
American Airlines
1:45 pmORD
1h 44m
Nonstop
4:29 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
7:10 amTYS
4h 49m
DTW · 1h 20m
10:59 amORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
5:35 pmTYS
2h 1m
Nonstop
6:36 pmORD
United Airlines
2:10 pmORD
1h 50m
Nonstop
5:00 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
11:33 amTYS
2h 7m
Nonstop
12:40 pmORD
American Airlines
1:45 pmORD
1h 44m
Nonstop
4:29 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
10:57 amTYS
2h 2m
Nonstop
11:59 amORD
United Airlines
10:25 amORD
1h 48m
Nonstop
1:13 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
5:35 pmTYS
2h 1m
Nonstop
6:36 pmORD
United Airlines
10:25 amORD
1h 48m
Nonstop
1:13 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD
American Airlines
12:05 pmORD
6h 26m
CLT · 3h 6m
7:31 pmTYS

Round-trip total · 1 adult · Taxes included

Show 5 more flights

Fri, Nov 20 – Mon, Nov 23

American Airlines
8:04 pmTYS
4h 55m
CLT · 1h 25m
11:59 pmORD
American Airlines
12:05 pmORD
6h 26m
CLT · 3h 6m
7:31 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
12:32 pmTYS
5h 34m
ATL · 2h 12m
5:06 pmORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
8:04 pmTYS
4h 55m
CLT · 1h 25m
11:59 pmORD
American Airlines
1:45 pmORD
1h 44m
Nonstop
4:29 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
12:32 pmTYS
5h 34m
ATL · 2h 12m
5:06 pmORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
7:10 amTYS
4h 49m
DTW · 1h 20m
10:59 amORD
Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
5:35 pmTYS
2h 1m
Nonstop
6:36 pmORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
12:32 pmTYS
5h 34m
ATL · 2h 12m
5:06 pmORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
11:33 amTYS
2h 7m
Nonstop
12:40 pmORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
10:57 amTYS
2h 2m
Nonstop
11:59 amORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
8:04 pmTYS
4h 55m
CLT · 1h 25m
11:59 pmORD

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
7:10 amTYS
4h 49m
DTW · 1h 20m
10:59 amORD

One-way total · 1 adult · Taxes included

Make this trip yours

TYS ⇄ ORD

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one wayAmerican AirlinesAA3653$165.002026-10-29T01:30:55Z
2026-11-20 · one wayUnited AirlinesUA5595$170.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23United AirlinesUA5921 / UA5693$310.002026-10-29T01:30:55Z
2026-11-27 → 2026-12-04American AirlinesAA3653 / AA4229$352.502026-10-29T01:30:55Z
2026-11-20 · one wayDelta Air LinesDL1743 + DL2738$190.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23Delta Air LinesDL5196 + DL3902 / DL1477 + DL5272$350.002026-10-29T01:30:55Z
2026-11-20 · one wayAmerican AirlinesAA5408$165.002026-10-29T01:30:55Z
2026-11-20 · one wayUnited AirlinesUA5921$170.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23United AirlinesUA5595 / UA5693$310.002026-10-29T01:30:55Z
2026-11-27 → 2026-12-04American AirlinesAA5408 / AA4229$352.502026-10-29T01:30:55Z
2026-11-27 → 2026-12-04United AirlinesUA5921 / UA4559$364.252026-10-29T01:30:55Z
2026-11-27 → 2026-12-04United AirlinesUA5595 / UA4559$364.252026-10-29T01:30:55Z
2026-11-20 · one wayAmerican AirlinesAA5675 + AA1039$180.002026-10-29T01:30:55Z
2026-11-20 · one wayDelta Air LinesDL5196 + DL3902$190.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23American AirlinesAA3653 / AA1889 + AA5301$315.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23American AirlinesAA5675 + AA1039 / AA1889 + AA5301$330.002026-10-29T01:30:55Z
2026-11-20 → 2026-11-23Delta Air LinesDL1743 + DL2738 / DL1477 + DL5272$350.002026-10-29T01:30:55Z
2026-11-27 → 2026-12-04American AirlinesAA5675 + AA1039 / AA4229$372.752026-10-29T01:30:55Z
2026-11-27 → 2026-12-04Delta Air LinesDL1743 + DL2738 / DL1477 + DL5272$411.252026-10-29T01:30:55Z
2026-11-27 → 2026-12-04Delta Air LinesDL5196 + DL3902 / DL1477 + DL5272$411.252026-10-29T01:30:55Z

2026-11-20 · one way · $165.00

  • American Airlines AA3653: TYS 2026-11-20 20:52:00 → ORD 2026-11-20 21:58:00; nonstop; 126 minutes. Local airport times.

2026-11-20 · one way · $170.00

  • United Airlines UA5595: TYS 2026-11-20 17:35:00 → ORD 2026-11-20 18:36:00; nonstop; 121 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $310.00

  • United Airlines UA5921: TYS 2026-11-20 10:57:00 → ORD 2026-11-20 11:59:00; nonstop; 122 minutes. Local airport times.
  • United Airlines UA5693: ORD 2026-11-23 14:10:00 → TYS 2026-11-23 17:00:00; nonstop; 110 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $352.50

  • American Airlines AA3653: TYS 2026-11-27 20:52:00 → ORD 2026-11-27 21:58:00; nonstop; 126 minutes. Local airport times.
  • American Airlines AA4229: ORD 2026-12-04 13:45:00 → TYS 2026-12-04 16:29:00; nonstop; 104 minutes. Local airport times.

2026-11-20 · one way · $190.00

  • Delta Air Lines DL1743 / DL2738: TYS 2026-11-20 12:32:00 → ORD 2026-11-20 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
    • DL1743: TYS 2026-11-20 12:32:00 → ATL 2026-11-20 13:38:00; layover at ATL: 132 minutes.
    • DL2738: ATL 2026-11-20 15:50:00 → ORD 2026-11-20 17:06:00.

2026-11-20 → 2026-11-23 · $350.00

  • Delta Air Lines DL5196 / DL3902: TYS 2026-11-20 07:10:00 → ORD 2026-11-20 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
    • DL5196: TYS 2026-11-20 07:10:00 → DTW 2026-11-20 09:00:00; layover at DTW: 80 minutes.
    • DL3902: DTW 2026-11-20 10:20:00 → ORD 2026-11-20 10:59:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-11-23 15:59:00 → TYS 2026-11-23 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-11-23 15:59:00 → ATL 2026-11-23 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-11-23 20:52:00 → TYS 2026-11-23 21:56:00.

2026-11-20 · one way · $165.00

  • American Airlines AA5408: TYS 2026-11-20 11:33:00 → ORD 2026-11-20 12:40:00; nonstop; 127 minutes. Local airport times.

2026-11-20 · one way · $170.00

  • United Airlines UA5921: TYS 2026-11-20 10:57:00 → ORD 2026-11-20 11:59:00; nonstop; 122 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $310.00

  • United Airlines UA5595: TYS 2026-11-20 17:35:00 → ORD 2026-11-20 18:36:00; nonstop; 121 minutes. Local airport times.
  • United Airlines UA5693: ORD 2026-11-23 14:10:00 → TYS 2026-11-23 17:00:00; nonstop; 110 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $352.50

  • American Airlines AA5408: TYS 2026-11-27 11:33:00 → ORD 2026-11-27 12:40:00; nonstop; 127 minutes. Local airport times.
  • American Airlines AA4229: ORD 2026-12-04 13:45:00 → TYS 2026-12-04 16:29:00; nonstop; 104 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $364.25

  • United Airlines UA5921: TYS 2026-11-27 10:57:00 → ORD 2026-11-27 11:59:00; nonstop; 122 minutes. Local airport times.
  • United Airlines UA4559: ORD 2026-12-04 10:25:00 → TYS 2026-12-04 13:13:00; nonstop; 108 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $364.25

  • United Airlines UA5595: TYS 2026-11-27 17:35:00 → ORD 2026-11-27 18:36:00; nonstop; 121 minutes. Local airport times.
  • United Airlines UA4559: ORD 2026-12-04 10:25:00 → TYS 2026-12-04 13:13:00; nonstop; 108 minutes. Local airport times.

2026-11-20 · one way · $180.00

  • American Airlines AA5675 / AA1039: TYS 2026-11-20 20:04:00 → ORD 2026-11-20 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
    • AA5675: TYS 2026-11-20 20:04:00 → CLT 2026-11-20 21:28:00; layover at CLT: 85 minutes.
    • AA1039: CLT 2026-11-20 22:53:00 → ORD 2026-11-20 23:59:00.

2026-11-20 · one way · $190.00

  • Delta Air Lines DL5196 / DL3902: TYS 2026-11-20 07:10:00 → ORD 2026-11-20 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
    • DL5196: TYS 2026-11-20 07:10:00 → DTW 2026-11-20 09:00:00; layover at DTW: 80 minutes.
    • DL3902: DTW 2026-11-20 10:20:00 → ORD 2026-11-20 10:59:00.

2026-11-20 → 2026-11-23 · $315.00

  • American Airlines AA3653: TYS 2026-11-20 20:52:00 → ORD 2026-11-20 21:58:00; nonstop; 126 minutes. Local airport times.
  • American Airlines AA1889 / AA5301: ORD 2026-11-23 12:05:00 → TYS 2026-11-23 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
    • AA1889: ORD 2026-11-23 12:05:00 → CLT 2026-11-23 15:10:00; layover at CLT: 186 minutes.
    • AA5301: CLT 2026-11-23 18:16:00 → TYS 2026-11-23 19:31:00.

2026-11-20 → 2026-11-23 · $330.00

  • American Airlines AA5675 / AA1039: TYS 2026-11-20 20:04:00 → ORD 2026-11-20 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
    • AA5675: TYS 2026-11-20 20:04:00 → CLT 2026-11-20 21:28:00; layover at CLT: 85 minutes.
    • AA1039: CLT 2026-11-20 22:53:00 → ORD 2026-11-20 23:59:00.
  • American Airlines AA1889 / AA5301: ORD 2026-11-23 12:05:00 → TYS 2026-11-23 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
    • AA1889: ORD 2026-11-23 12:05:00 → CLT 2026-11-23 15:10:00; layover at CLT: 186 minutes.
    • AA5301: CLT 2026-11-23 18:16:00 → TYS 2026-11-23 19:31:00.

2026-11-20 → 2026-11-23 · $350.00

  • Delta Air Lines DL1743 / DL2738: TYS 2026-11-20 12:32:00 → ORD 2026-11-20 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
    • DL1743: TYS 2026-11-20 12:32:00 → ATL 2026-11-20 13:38:00; layover at ATL: 132 minutes.
    • DL2738: ATL 2026-11-20 15:50:00 → ORD 2026-11-20 17:06:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-11-23 15:59:00 → TYS 2026-11-23 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-11-23 15:59:00 → ATL 2026-11-23 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-11-23 20:52:00 → TYS 2026-11-23 21:56:00.

2026-11-27 → 2026-12-04 · $372.75

  • American Airlines AA5675 / AA1039: TYS 2026-11-27 20:04:00 → ORD 2026-11-27 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
    • AA5675: TYS 2026-11-27 20:04:00 → CLT 2026-11-27 21:28:00; layover at CLT: 85 minutes.
    • AA1039: CLT 2026-11-27 22:53:00 → ORD 2026-11-27 23:59:00.
  • American Airlines AA4229: ORD 2026-12-04 13:45:00 → TYS 2026-12-04 16:29:00; nonstop; 104 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $411.25

  • Delta Air Lines DL1743 / DL2738: TYS 2026-11-27 12:32:00 → ORD 2026-11-27 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
    • DL1743: TYS 2026-11-27 12:32:00 → ATL 2026-11-27 13:38:00; layover at ATL: 132 minutes.
    • DL2738: ATL 2026-11-27 15:50:00 → ORD 2026-11-27 17:06:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-12-04 15:59:00 → TYS 2026-12-04 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-12-04 15:59:00 → ATL 2026-12-04 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-12-04 20:52:00 → TYS 2026-12-04 21:56:00.

2026-11-27 → 2026-12-04 · $411.25

  • Delta Air Lines DL5196 / DL3902: TYS 2026-11-27 07:10:00 → ORD 2026-11-27 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
    • DL5196: TYS 2026-11-27 07:10:00 → DTW 2026-11-27 09:00:00; layover at DTW: 80 minutes.
    • DL3902: DTW 2026-11-27 10:20:00 → ORD 2026-11-27 10:59:00.
  • Delta Air Lines DL1477 / DL5272: ORD 2026-12-04 15:59:00 → TYS 2026-12-04 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-12-04 15:59:00 → ATL 2026-12-04 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-12-04 20:52:00 → TYS 2026-12-04 21:56:00.

More dates for this route