Knoxville (TYS) to Chicago (ORD), Nov 12–16, 2026: from $310 round trip

Knoxville (TYS) to Chicago (ORD), Nov 12–16, 2026: from $310 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $310 round trip, Axel-exclusive, United Airlines, nonstop, Nov 12–16, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Chicago for these trips

Hotels: under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Chicago for these nights (Nov 12–16, 2026 · 4 nights · 2 adults, 1 room): 3★ Hyatt Place Chicago/Wicker Park · 4★ LondonHouse Chicago, Curio Collection by Hilton · 5★ The Langham, Chicago

All hotels in Chicago

Route overview: Knoxville to Chicago (ORD) flight deals

2026-11-12 → 2026-11-16 · Axel-exclusive $310.00

• United Airlines UA5245: TYS 2026-11-12 06:00:00 → ORD 2026-11-12 07:06:00; nonstop; 126 minutes. Local airport times.
• United Airlines UA4569: ORD 2026-11-16 06:55:00 → TYS 2026-11-16 09:53:00; nonstop; 118 minutes. Local airport times.

2026-11-12 → 2026-11-16 · Axel-exclusive $315.00

• American Airlines AA3653: TYS 2026-11-12 20:52:00 → ORD 2026-11-12 21:58:00; nonstop; 126 minutes. Local airport times.
• American Airlines AA1889 / AA5301: ORD 2026-11-16 12:05:00 → TYS 2026-11-16 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-11-16 12:05:00 → CLT 2026-11-16 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-11-16 18:16:00 → TYS 2026-11-16 19:31:00.

2026-11-12 → 2026-11-16 · Axel-exclusive $350.00

• Delta Air Lines DL1743 / DL2738: TYS 2026-11-12 12:32:00 → ORD 2026-11-12 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
  • DL1743: TYS 2026-11-12 12:32:00 → ATL 2026-11-12 13:38:00; layover at ATL: 132 minutes.
  • DL2738: ATL 2026-11-12 15:50:00 → ORD 2026-11-12 17:06:00.
• Delta Air Lines DL1477 / DL5272: ORD 2026-11-16 15:59:00 → TYS 2026-11-16 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-11-16 15:59:00 → ATL 2026-11-16 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-11-16 20:52:00 → TYS 2026-11-16 21:56:00.

2026-11-12 → 2026-11-16 · Axel-exclusive $310.00

• United Airlines UA5478: TYS 2026-11-12 17:40:00 → ORD 2026-11-12 18:43:00; nonstop; 123 minutes. Local airport times.
• United Airlines UA4569: ORD 2026-11-16 06:55:00 → TYS 2026-11-16 09:53:00; nonstop; 118 minutes. Local airport times.

2026-11-12 → 2026-11-16 · Axel-exclusive $330.00

• American Airlines AA5675 / AA1039: TYS 2026-11-12 20:04:00 → ORD 2026-11-12 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
  • AA5675: TYS 2026-11-12 20:04:00 → CLT 2026-11-12 21:28:00; layover at CLT: 85 minutes.
  • AA1039: CLT 2026-11-12 22:53:00 → ORD 2026-11-12 23:59:00.
• American Airlines AA1889 / AA5301: ORD 2026-11-16 12:05:00 → TYS 2026-11-16 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-11-16 12:05:00 → CLT 2026-11-16 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-11-16 18:16:00 → TYS 2026-11-16 19:31:00.

2026-11-12 → 2026-11-16 · Axel-exclusive $350.00

• Delta Air Lines DL5196 / DL3902: TYS 2026-11-12 07:10:00 → ORD 2026-11-12 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
  • DL5196: TYS 2026-11-12 07:10:00 → DTW 2026-11-12 09:00:00; layover at DTW: 80 minutes.
  • DL3902: DTW 2026-11-12 10:20:00 → ORD 2026-11-12 10:59:00.
• Delta Air Lines DL1477 / DL5272: ORD 2026-11-16 15:59:00 → TYS 2026-11-16 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-11-16 15:59:00 → ATL 2026-11-16 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-11-16 20:52:00 → TYS 2026-11-16 21:56:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 11, 2026 · Return options
• Nov 13, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

• This page: Knoxville (TYS) to Chicago (ORD) · Nov 12, 2026 · return Nov 16, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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