Knoxville (TYS) to Chicago (ORD) · Dec 19, 2026 · return Dec 21, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Knoxville to Chicago (ORD) flight deals

2026-12-19 → 2026-12-21 · Axel-exclusive $403.00

• United Airlines UA5921: TYS 2026-12-19 10:57:00 → ORD 2026-12-19 11:59:00; nonstop; 122 minutes. Local airport times.
• United Airlines UA5693: ORD 2026-12-21 14:10:00 → TYS 2026-12-21 17:00:00; nonstop; 110 minutes. Local airport times.

2026-12-19 → 2026-12-21 · Axel-exclusive $409.50

• American Airlines AA3653: TYS 2026-12-19 20:52:00 → ORD 2026-12-19 21:58:00; nonstop; 126 minutes. Local airport times.
• American Airlines AA1889 / AA5301: ORD 2026-12-21 12:05:00 → TYS 2026-12-21 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-12-21 12:05:00 → CLT 2026-12-21 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-12-21 18:16:00 → TYS 2026-12-21 19:31:00.

2026-12-19 → 2026-12-21 · Axel-exclusive $455.00

• Delta Air Lines DL1743 / DL2738: TYS 2026-12-19 12:32:00 → ORD 2026-12-19 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
  • DL1743: TYS 2026-12-19 12:32:00 → ATL 2026-12-19 13:38:00; layover at ATL: 132 minutes.
  • DL2738: ATL 2026-12-19 15:50:00 → ORD 2026-12-19 17:06:00.
• Delta Air Lines DL1477 / DL5272: ORD 2026-12-21 15:59:00 → TYS 2026-12-21 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-12-21 15:59:00 → ATL 2026-12-21 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-12-21 20:52:00 → TYS 2026-12-21 21:56:00.

2026-12-19 → 2026-12-21 · Axel-exclusive $403.00

• United Airlines UA5595: TYS 2026-12-19 17:35:00 → ORD 2026-12-19 18:36:00; nonstop; 121 minutes. Local airport times.
• United Airlines UA5693: ORD 2026-12-21 14:10:00 → TYS 2026-12-21 17:00:00; nonstop; 110 minutes. Local airport times.

2026-12-19 → 2026-12-21 · Axel-exclusive $429.00

• American Airlines AA5675 / AA1039: TYS 2026-12-19 20:04:00 → ORD 2026-12-19 23:59:00; 1 stop(s) via CLT; 295 minutes. Local airport times.
  • AA5675: TYS 2026-12-19 20:04:00 → CLT 2026-12-19 21:28:00; layover at CLT: 85 minutes.
  • AA1039: CLT 2026-12-19 22:53:00 → ORD 2026-12-19 23:59:00.
• American Airlines AA1889 / AA5301: ORD 2026-12-21 12:05:00 → TYS 2026-12-21 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-12-21 12:05:00 → CLT 2026-12-21 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-12-21 18:16:00 → TYS 2026-12-21 19:31:00.

2026-12-19 → 2026-12-21 · Axel-exclusive $455.00

• Delta Air Lines DL5196 / DL3902: TYS 2026-12-19 07:10:00 → ORD 2026-12-19 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
  • DL5196: TYS 2026-12-19 07:10:00 → DTW 2026-12-19 09:00:00; layover at DTW: 80 minutes.
  • DL3902: DTW 2026-12-19 10:20:00 → ORD 2026-12-19 10:59:00.
• Delta Air Lines DL1477 / DL5272: ORD 2026-12-21 15:59:00 → TYS 2026-12-21 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-12-21 15:59:00 → ATL 2026-12-21 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-12-21 20:52:00 → TYS 2026-12-21 21:56:00.

Explore this route

• All dates for this route
• Dec 18, 2026 · Return options
• Dec 20, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

• This page: Knoxville (TYS) to Chicago (ORD) · Dec 19, 2026 · return Dec 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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