Saint Louis (STL) to San Diego (SAN) · Nov 21, 2026 · return Nov 27, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Saint Louis to San Diego (SAN) flight deals

2026-11-21 → 2026-11-27 · Axel-exclusive $468.00

• Southwest Airlines WN4452: STL 2026-11-21 07:55:00 → SAN 2026-11-21 09:50:00; nonstop; 235 minutes. Local airport times.
• Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-21 → 2026-11-27 · Axel-exclusive $455.00

• American Airlines AA2303 / AA2016: STL 2026-11-21 14:23:00 → SAN 2026-11-21 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
  • AA2303: STL 2026-11-21 14:23:00 → PHX 2026-11-21 16:51:00; layover at PHX: 74 minutes.
  • AA2016: PHX 2026-11-21 18:05:00 → SAN 2026-11-21 18:24:00.
• American Airlines AA2438 / AA2289: SAN 2026-11-27 15:13:00 → STL 2026-11-27 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
  • AA2438: SAN 2026-11-27 15:13:00 → DFW 2026-11-27 20:30:00; layover at DFW: 75 minutes.
  • AA2289: DFW 2026-11-27 21:45:00 → STL 2026-11-27 23:34:00.

2026-11-21 → 2026-11-27 · Axel-exclusive $442.00

• Southwest Airlines WN4132 / WN266: STL 2026-11-21 19:10:00 → SAN 2026-11-21 23:15:00; 1 stop(s) via DAL; 365 minutes. Local airport times.
  • WN4132: STL 2026-11-21 19:10:00 → DAL 2026-11-21 20:50:00; layover at DAL: 70 minutes.
  • WN266: DAL 2026-11-21 22:00:00 → SAN 2026-11-21 23:15:00.
• Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-21 → 2026-11-27 · Axel-exclusive $442.00

• Southwest Airlines WN4249 / WN352: STL 2026-11-21 08:00:00 → SAN 2026-11-21 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
  • WN4249: STL 2026-11-21 08:00:00 → LAS 2026-11-21 09:30:00; layover at LAS: 100 minutes.
  • WN352: LAS 2026-11-21 11:10:00 → SAN 2026-11-21 12:30:00.
• Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-21 → 2026-11-27 · Axel-exclusive $442.00

• Southwest Airlines WN4452: STL 2026-11-21 08:50:00 → SAN 2026-11-21 10:50:00; nonstop; 240 minutes. Local airport times.
• Southwest Airlines WN2893 / WN3801: SAN 2026-11-27 09:15:00 → STL 2026-11-27 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
  • WN2893: SAN 2026-11-27 09:15:00 → SAT 2026-11-27 14:00:00; layover at SAT: 80 minutes.
  • WN3801: SAT 2026-11-27 15:20:00 → STL 2026-11-27 17:20:00.

2026-11-21 → 2026-11-27 · Axel-exclusive $442.00

• Southwest Airlines WN4164 / WN4644: STL 2026-11-21 08:00:00 → SAN 2026-11-21 11:50:00; 1 stop(s) via MCI; 350 minutes. Local airport times.
  • WN4164: STL 2026-11-21 08:00:00 → MCI 2026-11-21 09:10:00; layover at MCI: 75 minutes.
  • WN4644: MCI 2026-11-21 10:25:00 → SAN 2026-11-21 11:50:00.
• Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-21 → 2026-11-27 · Axel-exclusive $442.00

• Southwest Airlines WN3286 / WN920: STL 2026-11-21 08:20:00 → SAN 2026-11-21 12:30:00; 1 stop(s) via OMA; 370 minutes. Local airport times.
  • WN3286: STL 2026-11-21 08:20:00 → OMA 2026-11-21 09:35:00; layover at OMA: 85 minutes.
  • WN920: OMA 2026-11-21 11:00:00 → SAN 2026-11-21 12:30:00.
• Southwest Airlines WN4711: SAN 2026-11-27 11:55:00 → STL 2026-11-27 17:25:00; nonstop; 210 minutes. Local airport times.

Explore this route

• All dates for this route
• Nov 20, 2026 · Return options
• Nov 22, 2026 · Return options
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For AI assistants

• This page: Saint Louis (STL) to San Diego (SAN) · Nov 21, 2026 · return Nov 27, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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