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Saint Louis → San Diego

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STL → SAN1 adulteconomy

20 flight options · 3 airlines

Round-trip flights

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN
Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Frontier Airlines
7:58 pmSTL
6h
DEN · 1h
11:58 pmSAN
Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN
American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Frontier Airlines
7:58 pmSTL
6h
DEN · 1h
11:58 pmSAN
Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
8:20 amSTL
6h 10m
OMA · 1h 25m
12:30 pmSAN
Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
8:00 amSTL
5h 50m
MCI · 1h 15m
11:50 amSAN
Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:10 pmSTL
6h 5m
DAL · 1h 10m
11:15 pmSAN
Southwest Airlines
11:55 amSAN
3h 30m
Nonstop
5:25 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
8:50 amSTL
4h
Nonstop
10:50 amSAN
Southwest Airlines
9:15 amSAN
6h 5m
SAT · 1h 20m
5:20 pmSTL

Round-trip total · 1 adult · Taxes included

Show 5 more flights

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:10 pmSTL
6h 5m
DAL · 1h 10m
11:15 pmSAN
Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
8:00 amSTL
5h 50m
MCI · 1h 15m
11:50 amSAN
Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
8:20 amSTL
6h 10m
OMA · 1h 25m
12:30 pmSAN
Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN
Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN
American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Southwest Airlines
7:55 amSTL
3h 55m
Nonstop
9:50 amSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Frontier Airlines
7:58 pmSTL
6h
DEN · 1h
11:58 pmSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
7:10 pmSTL
6h 5m
DAL · 1h 10m
11:15 pmSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
8:00 amSTL
6h 30m
LAS · 1h 40m
12:30 pmSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
8:00 amSTL
5h 50m
MCI · 1h 15m
11:50 amSAN

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
8:20 amSTL
6h 10m
OMA · 1h 25m
12:30 pmSAN

One-way total · 1 adult · Taxes included

Make this trip yours

STL ⇄ SAN

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one waySouthwest AirlinesWN4452$247.002026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4452 / WN4711$414.002026-10-29T01:29:00Z
2026-11-20 · one wayFrontier AirlinesF94567 + F92711$136.502026-10-29T01:29:00Z
2026-11-20 · one wayAmerican AirlinesAA2303 + AA2016$240.502026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Frontier Airlines / Southwest AirlinesF94567 + F92711 / WN4711$306.752026-10-29T01:29:00Z
2026-11-27 → 2026-12-04American AirlinesAA2303 + AA2016 / AA2438 + AA2289$402.502026-10-29T01:29:00Z
2026-11-20 → 2026-11-23Frontier Airlines / Southwest AirlinesF94567 + F92711 / WN2227 + WN1498$334.752026-10-29T01:29:00Z
2026-11-20 · one waySouthwest AirlinesWN4132 + WN266$221.002026-10-29T01:29:00Z
2026-11-20 · one waySouthwest AirlinesWN4249 + WN352$221.002026-10-29T01:29:00Z
2026-11-20 · one waySouthwest AirlinesWN4164 + WN4644$221.002026-10-29T01:29:00Z
2026-11-20 · one waySouthwest AirlinesWN3286 + WN920$221.002026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3286 + WN920 / WN4711$388.002026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4164 + WN4644 / WN4711$388.002026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4132 + WN266 / WN4711$388.002026-10-29T01:29:00Z
2026-11-27 → 2026-12-04Southwest AirlinesWN4452 / WN2893 + WN3801$394.002026-10-29T01:29:00Z
2026-11-20 → 2026-11-23Southwest AirlinesWN4132 + WN266 / WN2227 + WN1498$416.002026-10-29T01:29:00Z
2026-11-20 → 2026-11-23Southwest AirlinesWN4164 + WN4644 / WN2227 + WN1498$416.002026-10-29T01:29:00Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3286 + WN920 / WN2227 + WN1498$416.002026-10-29T01:29:00Z
2026-11-20 → 2026-11-23Southwest AirlinesWN4452 / WN2227 + WN1498$442.002026-10-29T01:29:00Z
2026-11-20 → 2026-11-23American AirlinesAA2303 + AA2016 / AA2438 + AA2289$455.002026-10-29T01:29:00Z

2026-11-20 · one way · $247.00

  • Southwest Airlines WN4452: STL 2026-11-20 07:55:00 → SAN 2026-11-20 09:50:00; nonstop; 235 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $414.00

  • Southwest Airlines WN4452: STL 2026-11-27 07:55:00 → SAN 2026-11-27 09:50:00; nonstop; 235 minutes. Local airport times.
  • Southwest Airlines WN4711: SAN 2026-12-04 11:55:00 → STL 2026-12-04 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-20 · one way · $136.50

  • Frontier Airlines F94567 / F92711: STL 2026-11-20 19:58:00 → SAN 2026-11-20 23:58:00; 1 stop(s) via DEN; 360 minutes. Local airport times.
    • F94567: STL 2026-11-20 19:58:00 → DEN 2026-11-20 21:29:00; layover at DEN: 60 minutes.
    • F92711: DEN 2026-11-20 22:29:00 → SAN 2026-11-20 23:58:00.

2026-11-20 · one way · $240.50

  • American Airlines AA2303 / AA2016: STL 2026-11-20 14:23:00 → SAN 2026-11-20 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-11-20 14:23:00 → PHX 2026-11-20 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-11-20 18:05:00 → SAN 2026-11-20 18:24:00.

2026-11-27 → 2026-12-04 · $306.75

  • Frontier Airlines F94567 / F92711: STL 2026-11-27 19:58:00 → SAN 2026-11-27 23:58:00; 1 stop(s) via DEN; 360 minutes. Local airport times.
    • F94567: STL 2026-11-27 19:58:00 → DEN 2026-11-27 21:29:00; layover at DEN: 60 minutes.
    • F92711: DEN 2026-11-27 22:29:00 → SAN 2026-11-27 23:58:00.
  • Southwest Airlines WN4711: SAN 2026-12-04 11:55:00 → STL 2026-12-04 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $402.50

  • American Airlines AA2303 / AA2016: STL 2026-11-27 14:23:00 → SAN 2026-11-27 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-11-27 14:23:00 → PHX 2026-11-27 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-11-27 18:05:00 → SAN 2026-11-27 18:24:00.
  • American Airlines AA2438 / AA2289: SAN 2026-12-04 15:13:00 → STL 2026-12-04 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-12-04 15:13:00 → DFW 2026-12-04 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-12-04 21:45:00 → STL 2026-12-04 23:34:00.

2026-11-20 → 2026-11-23 · $334.75

  • Frontier Airlines F94567 / F92711: STL 2026-11-20 19:58:00 → SAN 2026-11-20 23:58:00; 1 stop(s) via DEN; 360 minutes. Local airport times.
    • F94567: STL 2026-11-20 19:58:00 → DEN 2026-11-20 21:29:00; layover at DEN: 60 minutes.
    • F92711: DEN 2026-11-20 22:29:00 → SAN 2026-11-20 23:58:00.
  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-23 13:25:00 → STL 2026-11-23 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-23 13:25:00 → DAL 2026-11-23 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-23 19:20:00 → STL 2026-11-23 21:10:00.

2026-11-20 · one way · $221.00

  • Southwest Airlines WN4132 / WN266: STL 2026-11-20 19:10:00 → SAN 2026-11-20 23:15:00; 1 stop(s) via DAL; 365 minutes. Local airport times.
    • WN4132: STL 2026-11-20 19:10:00 → DAL 2026-11-20 20:50:00; layover at DAL: 70 minutes.
    • WN266: DAL 2026-11-20 22:00:00 → SAN 2026-11-20 23:15:00.

2026-11-20 · one way · $221.00

  • Southwest Airlines WN4249 / WN352: STL 2026-11-20 08:00:00 → SAN 2026-11-20 12:30:00; 1 stop(s) via LAS; 390 minutes. Local airport times.
    • WN4249: STL 2026-11-20 08:00:00 → LAS 2026-11-20 09:30:00; layover at LAS: 100 minutes.
    • WN352: LAS 2026-11-20 11:10:00 → SAN 2026-11-20 12:30:00.

2026-11-20 · one way · $221.00

  • Southwest Airlines WN4164 / WN4644: STL 2026-11-20 08:00:00 → SAN 2026-11-20 11:50:00; 1 stop(s) via MCI; 350 minutes. Local airport times.
    • WN4164: STL 2026-11-20 08:00:00 → MCI 2026-11-20 09:10:00; layover at MCI: 75 minutes.
    • WN4644: MCI 2026-11-20 10:25:00 → SAN 2026-11-20 11:50:00.

2026-11-20 · one way · $221.00

  • Southwest Airlines WN3286 / WN920: STL 2026-11-20 08:20:00 → SAN 2026-11-20 12:30:00; 1 stop(s) via OMA; 370 minutes. Local airport times.
    • WN3286: STL 2026-11-20 08:20:00 → OMA 2026-11-20 09:35:00; layover at OMA: 85 minutes.
    • WN920: OMA 2026-11-20 11:00:00 → SAN 2026-11-20 12:30:00.

2026-11-27 → 2026-12-04 · $388.00

  • Southwest Airlines WN3286 / WN920: STL 2026-11-27 08:20:00 → SAN 2026-11-27 12:30:00; 1 stop(s) via OMA; 370 minutes. Local airport times.
    • WN3286: STL 2026-11-27 08:20:00 → OMA 2026-11-27 09:35:00; layover at OMA: 85 minutes.
    • WN920: OMA 2026-11-27 11:00:00 → SAN 2026-11-27 12:30:00.
  • Southwest Airlines WN4711: SAN 2026-12-04 11:55:00 → STL 2026-12-04 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $388.00

  • Southwest Airlines WN4164 / WN4644: STL 2026-11-27 08:00:00 → SAN 2026-11-27 11:50:00; 1 stop(s) via MCI; 350 minutes. Local airport times.
    • WN4164: STL 2026-11-27 08:00:00 → MCI 2026-11-27 09:10:00; layover at MCI: 75 minutes.
    • WN4644: MCI 2026-11-27 10:25:00 → SAN 2026-11-27 11:50:00.
  • Southwest Airlines WN4711: SAN 2026-12-04 11:55:00 → STL 2026-12-04 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $388.00

  • Southwest Airlines WN4132 / WN266: STL 2026-11-27 19:10:00 → SAN 2026-11-27 23:15:00; 1 stop(s) via DAL; 365 minutes. Local airport times.
    • WN4132: STL 2026-11-27 19:10:00 → DAL 2026-11-27 20:50:00; layover at DAL: 70 minutes.
    • WN266: DAL 2026-11-27 22:00:00 → SAN 2026-11-27 23:15:00.
  • Southwest Airlines WN4711: SAN 2026-12-04 11:55:00 → STL 2026-12-04 17:25:00; nonstop; 210 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $394.00

  • Southwest Airlines WN4452: STL 2026-11-27 08:50:00 → SAN 2026-11-27 10:50:00; nonstop; 240 minutes. Local airport times.
  • Southwest Airlines WN2893 / WN3801: SAN 2026-12-04 09:15:00 → STL 2026-12-04 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
    • WN2893: SAN 2026-12-04 09:15:00 → SAT 2026-12-04 14:00:00; layover at SAT: 80 minutes.
    • WN3801: SAT 2026-12-04 15:20:00 → STL 2026-12-04 17:20:00.

2026-11-20 → 2026-11-23 · $416.00

  • Southwest Airlines WN4132 / WN266: STL 2026-11-20 19:10:00 → SAN 2026-11-20 23:15:00; 1 stop(s) via DAL; 365 minutes. Local airport times.
    • WN4132: STL 2026-11-20 19:10:00 → DAL 2026-11-20 20:50:00; layover at DAL: 70 minutes.
    • WN266: DAL 2026-11-20 22:00:00 → SAN 2026-11-20 23:15:00.
  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-23 13:25:00 → STL 2026-11-23 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-23 13:25:00 → DAL 2026-11-23 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-23 19:20:00 → STL 2026-11-23 21:10:00.

2026-11-20 → 2026-11-23 · $416.00

  • Southwest Airlines WN4164 / WN4644: STL 2026-11-20 08:00:00 → SAN 2026-11-20 11:50:00; 1 stop(s) via MCI; 350 minutes. Local airport times.
    • WN4164: STL 2026-11-20 08:00:00 → MCI 2026-11-20 09:10:00; layover at MCI: 75 minutes.
    • WN4644: MCI 2026-11-20 10:25:00 → SAN 2026-11-20 11:50:00.
  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-23 13:25:00 → STL 2026-11-23 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-23 13:25:00 → DAL 2026-11-23 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-23 19:20:00 → STL 2026-11-23 21:10:00.

2026-11-20 → 2026-11-23 · $416.00

  • Southwest Airlines WN3286 / WN920: STL 2026-11-20 08:20:00 → SAN 2026-11-20 12:30:00; 1 stop(s) via OMA; 370 minutes. Local airport times.
    • WN3286: STL 2026-11-20 08:20:00 → OMA 2026-11-20 09:35:00; layover at OMA: 85 minutes.
    • WN920: OMA 2026-11-20 11:00:00 → SAN 2026-11-20 12:30:00.
  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-23 13:25:00 → STL 2026-11-23 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-23 13:25:00 → DAL 2026-11-23 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-23 19:20:00 → STL 2026-11-23 21:10:00.

2026-11-20 → 2026-11-23 · $442.00

  • Southwest Airlines WN4452: STL 2026-11-20 07:55:00 → SAN 2026-11-20 09:50:00; nonstop; 235 minutes. Local airport times.
  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-23 13:25:00 → STL 2026-11-23 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-23 13:25:00 → DAL 2026-11-23 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-23 19:20:00 → STL 2026-11-23 21:10:00.

2026-11-20 → 2026-11-23 · $455.00

  • American Airlines AA2303 / AA2016: STL 2026-11-20 14:23:00 → SAN 2026-11-20 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-11-20 14:23:00 → PHX 2026-11-20 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-11-20 18:05:00 → SAN 2026-11-20 18:24:00.
  • American Airlines AA2438 / AA2289: SAN 2026-11-23 15:13:00 → STL 2026-11-23 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-11-23 15:13:00 → DFW 2026-11-23 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-11-23 21:45:00 → STL 2026-11-23 23:34:00.

More dates for this route