San Francisco (SFO) to Panama City (PTY), Dec 18–20, 2026: from $371 one way

San Francisco (SFO) to Panama City (PTY), Dec 18–20, 2026: from $371 one way on Axel, checked Oct 29, 2026. Lowest published fare: $371 one way, Axel-exclusive, Avianca, 1 stop, Dec 18, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: San Francisco Bay Area to Panama City (PTY) flight deals

2026-12-20 · one way · Axel-exclusive $492.75

• Copa Airlines CM409: SFO 2026-12-20 19:36:00 → PTY 2026-12-21 05:45:00; nonstop; 429 minutes. Local airport times.

2026-12-20 · one way · Axel-exclusive $371.25

• Avianca AV563 / AV317: SFO 2026-12-20 13:15:00 → PTY 2026-12-21 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
  • AV563: SFO 2026-12-20 13:15:00 → SAL 2026-12-20 20:50:00; layover at SAL: 135 minutes.
  • AV317: SAL 2026-12-20 23:05:00 → PTY 2026-12-21 02:10:00.

2026-12-19 · one way · Axel-exclusive $452.25

• American Airlines AA1665 / AA315: SFO 2026-12-19 00:37:00 → PTY 2026-12-19 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
  • AA1665: SFO 2026-12-19 00:37:00 → MIA 2026-12-19 09:06:00; layover at MIA: 81 minutes.
  • AA315: MIA 2026-12-19 10:27:00 → PTY 2026-12-19 13:41:00.

2026-12-20 · one way · Axel-exclusive $465.75

• United Airlines UA2862 / CM473: SFO 2026-12-20 21:22:00 → PTY 2026-12-21 09:50:00; 1 stop(s) via LAX; 568 minutes. Local airport times.
  • UA2862: SFO 2026-12-20 21:22:00 → LAX 2026-12-20 22:52:00; layover at LAX: 83 minutes.
  • CM473: LAX 2026-12-21 00:15:00 → PTY 2026-12-21 09:50:00.

2026-12-18 · one way · Axel-exclusive $492.75

• Copa Airlines CM409: SFO 2026-12-18 19:36:00 → PTY 2026-12-19 05:45:00; nonstop; 429 minutes. Local airport times.

2026-12-19 · one way · Axel-exclusive $492.75

• Copa Airlines CM409: SFO 2026-12-19 19:36:00 → PTY 2026-12-20 05:45:00; nonstop; 429 minutes. Local airport times.

2026-12-20 · one way · Axel-exclusive $492.75

• Copa Airlines CM383: SFO 2026-12-20 00:33:00 → PTY 2026-12-20 10:46:00; nonstop; 433 minutes. Local airport times.

2026-12-19 · one way · Axel-exclusive $492.75

• Copa Airlines CM383: SFO 2026-12-19 00:33:00 → PTY 2026-12-19 10:46:00; nonstop; 433 minutes. Local airport times.

2026-12-18 · one way · Axel-exclusive $492.75

• Copa Airlines CM383: SFO 2026-12-18 00:33:00 → PTY 2026-12-18 10:46:00; nonstop; 433 minutes. Local airport times.

2026-12-19 · one way · Axel-exclusive $371.25

• Avianca AV563 / AV317: SFO 2026-12-19 13:15:00 → PTY 2026-12-20 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
  • AV563: SFO 2026-12-19 13:15:00 → SAL 2026-12-19 20:50:00; layover at SAL: 135 minutes.
  • AV317: SAL 2026-12-19 23:05:00 → PTY 2026-12-20 02:10:00.

2026-12-18 · one way · Axel-exclusive $371.25

• Avianca AV563 / AV317: SFO 2026-12-18 13:15:00 → PTY 2026-12-19 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
  • AV563: SFO 2026-12-18 13:15:00 → SAL 2026-12-18 20:50:00; layover at SAL: 135 minutes.
  • AV317: SAL 2026-12-18 23:05:00 → PTY 2026-12-19 02:10:00.

2026-12-18 · one way · Axel-exclusive $452.25

• American Airlines AA1665 / AA315: SFO 2026-12-18 00:37:00 → PTY 2026-12-18 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
  • AA1665: SFO 2026-12-18 00:37:00 → MIA 2026-12-18 09:06:00; layover at MIA: 81 minutes.
  • AA315: MIA 2026-12-18 10:27:00 → PTY 2026-12-18 13:41:00.

2026-12-20 · one way · Axel-exclusive $452.25

• American Airlines AA1665 / AA315: SFO 2026-12-20 00:37:00 → PTY 2026-12-20 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
  • AA1665: SFO 2026-12-20 00:37:00 → MIA 2026-12-20 09:06:00; layover at MIA: 81 minutes.
  • AA315: MIA 2026-12-20 10:27:00 → PTY 2026-12-20 13:41:00.

2026-12-20 · one way · Axel-exclusive $465.75

• United Airlines UA1491 / CM445: SFO 2026-12-20 07:29:00 → PTY 2026-12-20 20:27:00; 1 stop(s) via MCO; 598 minutes. Local airport times.
  • UA1491: SFO 2026-12-20 07:29:00 → MCO 2026-12-20 15:43:00; layover at MCO: 76 minutes.
  • CM445: MCO 2026-12-20 16:59:00 → PTY 2026-12-20 20:27:00.

2026-12-20 · one way · Axel-exclusive $465.75

• United Airlines UA2722 / CM266: SFO 2026-12-20 07:15:00 → PTY 2026-12-20 20:19:00; 1 stop(s) via FLL; 604 minutes. Local airport times.
  • UA2722: SFO 2026-12-20 07:15:00 → FLL 2026-12-20 15:45:00; layover at FLL: 83 minutes.
  • CM266: FLL 2026-12-20 17:08:00 → PTY 2026-12-20 20:19:00.

2026-12-19 · one way · Axel-exclusive $465.75

• United Airlines UA2862 / CM473: SFO 2026-12-19 21:22:00 → PTY 2026-12-20 09:50:00; 1 stop(s) via LAX; 568 minutes. Local airport times.
  • UA2862: SFO 2026-12-19 21:22:00 → LAX 2026-12-19 22:52:00; layover at LAX: 83 minutes.
  • CM473: LAX 2026-12-20 00:15:00 → PTY 2026-12-20 09:50:00.

2026-12-18 · one way · Axel-exclusive $465.75

• United Airlines UA2862 / CM473: SFO 2026-12-18 21:22:00 → PTY 2026-12-19 09:50:00; 1 stop(s) via LAX; 568 minutes. Local airport times.
  • UA2862: SFO 2026-12-18 21:22:00 → LAX 2026-12-18 22:52:00; layover at LAX: 83 minutes.
  • CM473: LAX 2026-12-19 00:15:00 → PTY 2026-12-19 09:50:00.

2026-12-19 · one way · Axel-exclusive $465.75

• United Airlines UA406 / CM253: SFO 2026-12-19 21:05:00 → PTY 2026-12-20 10:14:00; 1 stop(s) via LAS; 609 minutes. Local airport times.
  • UA406: SFO 2026-12-19 21:05:00 → LAS 2026-12-19 22:44:00; layover at LAS: 122 minutes.
  • CM253: LAS 2026-12-20 00:46:00 → PTY 2026-12-20 10:14:00.

2026-12-18 · one way · Axel-exclusive $465.75

• United Airlines UA1491 / CM445: SFO 2026-12-18 07:29:00 → PTY 2026-12-18 20:27:00; 1 stop(s) via MCO; 598 minutes. Local airport times.
  • UA1491: SFO 2026-12-18 07:29:00 → MCO 2026-12-18 15:43:00; layover at MCO: 76 minutes.
  • CM445: MCO 2026-12-18 16:59:00 → PTY 2026-12-18 20:27:00.

2026-12-20 · one way · Axel-exclusive $465.75

• United Airlines UA406 / CM253: SFO 2026-12-20 21:05:00 → PTY 2026-12-21 10:14:00; 1 stop(s) via LAS; 609 minutes. Local airport times.
  • UA406: SFO 2026-12-20 21:05:00 → LAS 2026-12-20 22:44:00; layover at LAS: 122 minutes.
  • CM253: LAS 2026-12-21 00:46:00 → PTY 2026-12-21 10:14:00.

2026-12-18 · one way · Axel-exclusive $465.75

• United Airlines UA406 / CM253: SFO 2026-12-18 21:05:00 → PTY 2026-12-19 10:14:00; 1 stop(s) via LAS; 609 minutes. Local airport times.
  • UA406: SFO 2026-12-18 21:05:00 → LAS 2026-12-18 22:44:00; layover at LAS: 122 minutes.
  • CM253: LAS 2026-12-19 00:46:00 → PTY 2026-12-19 10:14:00.

2026-12-19 · one way · Axel-exclusive $465.75

• United Airlines UA2722 / CM266: SFO 2026-12-19 07:15:00 → PTY 2026-12-19 20:19:00; 1 stop(s) via FLL; 604 minutes. Local airport times.
  • UA2722: SFO 2026-12-19 07:15:00 → FLL 2026-12-19 15:45:00; layover at FLL: 83 minutes.
  • CM266: FLL 2026-12-19 17:08:00 → PTY 2026-12-19 20:19:00.

2026-12-19 · one way · Axel-exclusive $465.75

• United Airlines UA1491 / CM445: SFO 2026-12-19 07:29:00 → PTY 2026-12-19 20:27:00; 1 stop(s) via MCO; 598 minutes. Local airport times.
  • UA1491: SFO 2026-12-19 07:29:00 → MCO 2026-12-19 15:43:00; layover at MCO: 76 minutes.
  • CM445: MCO 2026-12-19 16:59:00 → PTY 2026-12-19 20:27:00.

2026-12-18 · one way · Axel-exclusive $465.75

• United Airlines UA2722 / CM266: SFO 2026-12-18 07:15:00 → PTY 2026-12-18 20:19:00; 1 stop(s) via FLL; 604 minutes. Local airport times.
  • UA2722: SFO 2026-12-18 07:15:00 → FLL 2026-12-18 15:45:00; layover at FLL: 83 minutes.
  • CM266: FLL 2026-12-18 17:08:00 → PTY 2026-12-18 20:19:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

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