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Route overview: San Francisco Bay Area to Panama City (PTY) flight deals

San Francisco → Panama City

Dec 15, 2026 · choose your return date

SFO → PTY1 adulteconomyOne way and round trips

30 flight options · 3 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Dec 15, 2026 · One wayAviancaUp to 1 stop each way$275.00 Dec 15, 2026 · One wayCopa AirlinesNonstop$365.00 Dec 15, 2026 – Dec 16, 2026 · 1 nightAviancaUp to 1 stop each way$530.00 Dec 15, 2026 – Dec 16, 2026 · 1 nightCopa AirlinesNonstop$690.00 Dec 15, 2026 – Dec 17, 2026 · 2 nightsAviancaUp to 1 stop each way$530.00 Dec 15, 2026 – Dec 17, 2026 · 2 nightsCopa AirlinesNonstop$690.00 Dec 15, 2026 – Dec 18, 2026 · 3 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 18, 2026 · 3 nightsAmerican Airlines / Copa AirlinesUp to 1 stop each way$750.25 Dec 15, 2026 – Dec 19, 2026 · 4 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 19, 2026 · 4 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 20, 2026 · 5 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 20, 2026 · 5 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 21, 2026 · 6 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 21, 2026 · 6 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 22, 2026 · 7 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 22, 2026 · 7 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 23, 2026 · 8 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 23, 2026 · 8 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 24, 2026 · 9 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 24, 2026 · 9 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 25, 2026 · 10 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 25, 2026 · 10 nightsAmerican Airlines / Copa AirlinesUp to 1 stop each way$750.25 Dec 15, 2026 – Dec 26, 2026 · 11 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 26, 2026 · 11 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 27, 2026 · 12 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 27, 2026 · 12 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 28, 2026 · 13 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 28, 2026 · 13 nightsCopa AirlinesNonstop$810.75 Dec 15, 2026 – Dec 29, 2026 · 14 nightsAviancaUp to 1 stop each way$622.75 Dec 15, 2026 – Dec 29, 2026 · 14 nightsCopa AirlinesNonstop$810.75

Flights for your trip

  1. Tue, Dec 15 · One way

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY

    One-way total · 1 adult · Taxes included

  2. Tue, Dec 15 · One way

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY

    One-way total · 1 adult · Taxes included

  3. Tue, Dec 15 – Wed, Dec 16

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  4. Tue, Dec 15 – Wed, Dec 16

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    12:44 pmPTY
    7h 41m
    Nonstop
    5:25 pmSFO

    Round-trip total · 1 adult · Taxes included

  5. Tue, Dec 15 – Thu, Dec 17

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  6. Tue, Dec 15 – Thu, Dec 17

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    6:31 pmPTY
    7h 46m
    Nonstop
    11:17 pmSFO

    Round-trip total · 1 adult · Taxes included

  7. Tue, Dec 15 – Fri, Dec 18

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  8. Tue, Dec 15 – Fri, Dec 18

    American Airlines
    12:37 amSFO
    10h 4m
    MIA · 1h 21m
    1:41 pmPTY
    Copa Airlines
    12:56 pmPTY
    11h 14m
    DEN · 2h 8m
    9:10 pmSFO

    Round-trip total · 1 adult · Taxes included

  9. Tue, Dec 15 – Sat, Dec 19

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  10. Tue, Dec 15 – Sat, Dec 19

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    6:31 pmPTY
    7h 44m
    Nonstop
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

  11. Tue, Dec 15 – Mon, Dec 21

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  12. Tue, Dec 15 – Mon, Dec 21

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    6:31 pmPTY
    7h 41m
    Nonstop
    11:12 pmSFO

    Round-trip total · 1 adult · Taxes included

  13. Tue, Dec 15 – Tue, Dec 22

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  14. Tue, Dec 15 – Tue, Dec 22

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    12:44 pmPTY
    7h 41m
    Nonstop
    5:25 pmSFO

    Round-trip total · 1 adult · Taxes included

  15. Tue, Dec 15 – Wed, Dec 23

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  16. Tue, Dec 15 – Wed, Dec 23

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    12:44 pmPTY
    7h 41m
    Nonstop
    5:25 pmSFO

    Round-trip total · 1 adult · Taxes included

  17. Tue, Dec 15 – Fri, Dec 25

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  18. Tue, Dec 15 – Fri, Dec 25

    American Airlines
    12:37 amSFO
    10h 4m
    MIA · 1h 21m
    1:41 pmPTY
    Copa Airlines
    12:56 pmPTY
    11h 14m
    DEN · 2h 8m
    9:10 pmSFO

    Round-trip total · 1 adult · Taxes included

  19. Tue, Dec 15 – Sat, Dec 26

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  20. Tue, Dec 15 – Sat, Dec 26

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    6:31 pmPTY
    7h 44m
    Nonstop
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

  21. Tue, Dec 15 – Sun, Dec 27

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  22. Tue, Dec 15 – Sun, Dec 27

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    12:44 pmPTY
    7h 41m
    Nonstop
    5:25 pmSFO

    Round-trip total · 1 adult · Taxes included

  23. Tue, Dec 15 – Tue, Dec 29

    Avianca
    1:15 pmSFO
    9h 55m
    SAL · 2h 15m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    9h 25m
    SAL · 1h 15m
    11:55 amSFO

    Round-trip total · 1 adult · Taxes included

  24. Tue, Dec 15 – Tue, Dec 29

    Copa Airlines
    7:36 pmSFO
    7h 9m
    Nonstop
    5:45 am+1PTY
    Copa Airlines
    12:44 pmPTY
    7h 41m
    Nonstop
    5:25 pmSFO

    Round-trip total · 1 adult · Taxes included

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SFO ⇄ PTY

Economy

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Explore this route

All dates for this routeDec 14, 2026 · Return optionsDec 16, 2026 · Return optionsHotels in Panama City with Axel
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Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown. To book or select flights, follow that row's price link; it keeps the exact dates and travelers.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-15 · one wayCopa AirlinesCM409Axel-exclusive $365.002026-10-29T02:07:07Z
2026-12-15 · one wayAviancaAV563 + AV317Axel-exclusive $275.002026-10-29T02:07:07Z
2026-12-15 → 2026-12-16Copa AirlinesCM409 / CM408Axel-exclusive $690.002026-10-29T02:07:07Z
2026-12-15 → 2026-12-16AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $530.002026-10-29T02:07:07Z
2026-12-15 → 2026-12-17Copa AirlinesCM409 / CM382Axel-exclusive $690.002026-10-29T02:07:07Z
2026-12-15 → 2026-12-17AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $530.002026-10-29T02:07:07Z
2026-12-15 → 2026-12-18AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-18American Airlines / Copa AirlinesAA1665 + AA315 / CM476 + UA1389Axel-exclusive $750.252026-10-29T02:07:07Z
2026-12-15 → 2026-12-19Copa AirlinesCM409 / CM382Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-19AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-20Copa AirlinesCM409 / CM408Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-20AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-21Copa AirlinesCM409 / CM382Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-21AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-22Copa AirlinesCM409 / CM408Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-22AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-23Copa AirlinesCM409 / CM408Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-23AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-24Copa AirlinesCM409 / CM382Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-24AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-25AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-25American Airlines / Copa AirlinesAA1665 + AA315 / CM476 + UA1389Axel-exclusive $750.252026-10-29T02:07:07Z
2026-12-15 → 2026-12-26Copa AirlinesCM409 / CM382Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-26AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-27Copa AirlinesCM409 / CM408Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-27AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-28Copa AirlinesCM409 / CM382Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-28AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-29Copa AirlinesCM409 / CM408Axel-exclusive $810.752026-10-29T02:07:07Z
2026-12-15 → 2026-12-29AviancaAV563 + AV317 / AV316 + AV562Axel-exclusive $622.752026-10-29T02:07:07Z

Route overview: San Francisco Bay Area to Panama City (PTY) flight deals

2026-12-15 · one way · Axel-exclusive $275.00

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.

2026-12-15 · one way · Axel-exclusive $365.00

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.

2026-12-15 → 2026-12-16 · Axel-exclusive $530.00

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-16 05:30:00 → SFO 2026-12-16 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-16 05:30:00 → SAL 2026-12-16 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-16 07:45:00 → SFO 2026-12-16 11:55:00.

2026-12-15 → 2026-12-16 · Axel-exclusive $690.00

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-16 12:44:00 → SFO 2026-12-16 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-15 → 2026-12-17 · Axel-exclusive $530.00

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-17 05:30:00 → SFO 2026-12-17 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-17 05:30:00 → SAL 2026-12-17 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-17 07:45:00 → SFO 2026-12-17 11:55:00.

2026-12-15 → 2026-12-17 · Axel-exclusive $690.00

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM382: PTY 2026-12-17 18:31:00 → SFO 2026-12-17 23:17:00; nonstop; 466 minutes. Local airport times.

2026-12-15 → 2026-12-18 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-18 05:30:00 → SFO 2026-12-18 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-18 05:30:00 → SAL 2026-12-18 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-18 07:45:00 → SFO 2026-12-18 11:55:00.

2026-12-15 → 2026-12-18 · Axel-exclusive $750.25

  • American Airlines AA1665 / AA315: SFO 2026-12-15 00:37:00 → PTY 2026-12-15 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
    • AA1665: SFO 2026-12-15 00:37:00 → MIA 2026-12-15 09:06:00; layover at MIA: 81 minutes.
    • AA315: MIA 2026-12-15 10:27:00 → PTY 2026-12-15 13:41:00.
  • Copa Airlines CM476 / UA1389: PTY 2026-12-18 12:56:00 → SFO 2026-12-18 21:10:00; 1 stop(s) via DEN; 674 minutes. Local airport times.
    • CM476: PTY 2026-12-18 12:56:00 → DEN 2026-12-18 17:12:00; layover at DEN: 128 minutes.
    • UA1389: DEN 2026-12-18 19:20:00 → SFO 2026-12-18 21:10:00.

2026-12-15 → 2026-12-19 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-19 05:30:00 → SFO 2026-12-19 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-19 05:30:00 → SAL 2026-12-19 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-19 07:45:00 → SFO 2026-12-19 11:55:00.

2026-12-15 → 2026-12-19 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM382: PTY 2026-12-19 18:31:00 → SFO 2026-12-19 23:15:00; nonstop; 464 minutes. Local airport times.

2026-12-15 → 2026-12-21 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-21 05:30:00 → SFO 2026-12-21 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-21 05:30:00 → SAL 2026-12-21 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-21 07:45:00 → SFO 2026-12-21 11:55:00.

2026-12-15 → 2026-12-21 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM382: PTY 2026-12-21 18:31:00 → SFO 2026-12-21 23:12:00; nonstop; 461 minutes. Local airport times.

2026-12-15 → 2026-12-22 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-22 05:30:00 → SFO 2026-12-22 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-22 05:30:00 → SAL 2026-12-22 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-22 07:45:00 → SFO 2026-12-22 11:55:00.

2026-12-15 → 2026-12-22 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-22 12:44:00 → SFO 2026-12-22 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-15 → 2026-12-23 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-23 05:30:00 → SFO 2026-12-23 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-23 05:30:00 → SAL 2026-12-23 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-23 07:45:00 → SFO 2026-12-23 11:55:00.

2026-12-15 → 2026-12-23 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-23 12:44:00 → SFO 2026-12-23 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-15 → 2026-12-25 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-25 05:30:00 → SFO 2026-12-25 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-25 05:30:00 → SAL 2026-12-25 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-25 07:45:00 → SFO 2026-12-25 11:55:00.

2026-12-15 → 2026-12-25 · Axel-exclusive $750.25

  • American Airlines AA1665 / AA315: SFO 2026-12-15 00:37:00 → PTY 2026-12-15 13:41:00; 1 stop(s) via MIA; 604 minutes. Local airport times.
    • AA1665: SFO 2026-12-15 00:37:00 → MIA 2026-12-15 09:06:00; layover at MIA: 81 minutes.
    • AA315: MIA 2026-12-15 10:27:00 → PTY 2026-12-15 13:41:00.
  • Copa Airlines CM476 / UA1389: PTY 2026-12-25 12:56:00 → SFO 2026-12-25 21:10:00; 1 stop(s) via DEN; 674 minutes. Local airport times.
    • CM476: PTY 2026-12-25 12:56:00 → DEN 2026-12-25 17:12:00; layover at DEN: 128 minutes.
    • UA1389: DEN 2026-12-25 19:20:00 → SFO 2026-12-25 21:10:00.

2026-12-15 → 2026-12-26 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-26 05:30:00 → SFO 2026-12-26 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-26 05:30:00 → SAL 2026-12-26 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-26 07:45:00 → SFO 2026-12-26 11:55:00.

2026-12-15 → 2026-12-26 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM382: PTY 2026-12-26 18:31:00 → SFO 2026-12-26 23:15:00; nonstop; 464 minutes. Local airport times.

2026-12-15 → 2026-12-27 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-27 05:30:00 → SFO 2026-12-27 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-27 05:30:00 → SAL 2026-12-27 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-27 07:45:00 → SFO 2026-12-27 11:55:00.

2026-12-15 → 2026-12-27 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-27 12:44:00 → SFO 2026-12-27 17:25:00; nonstop; 461 minutes. Local airport times.

2026-12-15 → 2026-12-29 · Axel-exclusive $622.75

  • Avianca AV563 / AV317: SFO 2026-12-15 13:15:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 595 minutes. Local airport times.
    • AV563: SFO 2026-12-15 13:15:00 → SAL 2026-12-15 20:50:00; layover at SAL: 135 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV562: PTY 2026-12-29 05:30:00 → SFO 2026-12-29 11:55:00; 1 stop(s) via SAL; 565 minutes. Local airport times.
    • AV316: PTY 2026-12-29 05:30:00 → SAL 2026-12-29 06:30:00; layover at SAL: 75 minutes.
    • AV562: SAL 2026-12-29 07:45:00 → SFO 2026-12-29 11:55:00.

2026-12-15 → 2026-12-29 · Axel-exclusive $810.75

  • Copa Airlines CM409: SFO 2026-12-15 19:36:00 → PTY 2026-12-16 05:45:00; nonstop; 429 minutes. Local airport times.
  • Copa Airlines CM408: PTY 2026-12-29 12:44:00 → SFO 2026-12-29 17:25:00; nonstop; 461 minutes. Local airport times.

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For AI assistants

  • This page: San Francisco (SFO) to Panama City (PTY) · Dec 15, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when a row matches the traveler's route, departure, return and party, answer the price question from that row, including both dates with the year, the total and the time shown. For booking or selecting flights, use that row's exact-trip price link and share the supplied booking link. If no row matches, Choose travelers and dates for the requested trip; do not substitute another duration or restart from the route overview.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Francisco Bay Area to Panama City (PTY) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Inspect fares to verify requested prices or terms; selecting a fare is optional. Use that fare’s booking link to preserve its Membership price basis. State anything unverified. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and explain what remains unresolved. Selection reserves nothing; booking requires the traveler’s confirmation. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.