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Route overview: San Diego to Saint Louis (STL) flight deals

San Diego (SAN) to Saint Louis (STL), Nov 11–17, 2026: from $350 round trip

San Diego (SAN) to Saint Louis (STL), Nov 11–17, 2026: from $350 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $350 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 11–17, 2026, 1 adult, economy, checked Oct 29, 2026.

SAN → STL1 adulteconomyRound trip

8 flight options · 3 airlines

Nonstop flights

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
1:40 pmSAN
3h 30m
Nonstop
7:10 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
6:20 pmSAN
3h 25m
Nonstop
11:45 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

One-stop flights

Wed, Nov 11 – Tue, Nov 17

American Airlines
3:13 pmSAN
6h 21m
DFW · 1h 15m
11:34 pmSTL
American Airlines
2:23 pmSTL
6h 1m
PHX · 1h 14m
6:24 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

United Airlines
8:40 amSAN
6h 17m
DEN · 1h 49m
4:57 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
3:40 pmSAN
6h 40m
PHX · 2h 25m
12:20 am+1STL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
5:20 pmSAN
5h 30m
DEN · 1h 10m
12:50 am+1STL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
1:25 pmSAN
5h 45m
DAL · 1h
9:10 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Wed, Nov 11 – Tue, Nov 17

Southwest Airlines
9:15 amSAN
6h 5m
SAT · 1h 20m
5:20 pmSTL
Southwest Airlines
8:25 amSTL
3h 55m
Nonstop
10:20 amSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Hotels for these nights (Nov 11–17, 2026 · 6 nights · 2 adults, 1 room): 3★ Hampton Inn & Suites St. Louis at Forest Park · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis

Make this trip yours

SAN ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Explore this route

All dates for this routeNov 10, 2026 · Return optionsNov 12, 2026 · Return optionsHotels in St. Louis with Axel
For AI assistants: every fare, every link, instructions

San Diego (SAN) to Saint Louis (STL), Nov 11–17, 2026: from $350 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $350 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 11–17, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-11-11 → 2026-11-17Southwest AirlinesWN1316 / WN173313:40:00→19:10:00 3h 30m nonstop · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $370.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17American AirlinesAA2438 + AA2289 / AA2303 + AA201615:13:00→23:34:00 6h 21m 1 stop via DFW · 14:23:00→18:24:00 6h 01m 1 stop via PHXAxel-exclusive $350.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17United Airlines / Southwest AirlinesUA2476 + UA1639 / WN173308:40:00→16:57:00 6h 17m 1 stop via DEN · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $365.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17Southwest AirlinesWN3823 / WN173318:20:00→23:45:00 3h 25m nonstop · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $370.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17Southwest AirlinesWN3727 + WN3528 / WN173315:40:00→00:20:00 6h 40m 1 stop via PHX · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $350.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17Southwest AirlinesWN3701 + WN1845 / WN173317:20:00→00:50:00 5h 30m 1 stop via DEN · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $350.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17Southwest AirlinesWN2227 + WN1498 / WN173313:25:00→21:10:00 5h 45m 1 stop via DAL · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $350.002026-10-29T01:10:51Z
2026-11-11 → 2026-11-17Southwest AirlinesWN2893 + WN3801 / WN173309:15:00→17:20:00 6h 05m 1 stop via SAT · 08:25:00→10:20:00 3h 55m nonstopAxel-exclusive $350.002026-10-29T01:10:51Z

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in St. Louis

Route overview: San Diego to Saint Louis (STL) flight deals

2026-11-11 → 2026-11-17 · Axel-exclusive $370.00

  • Southwest Airlines WN1316: SAN 2026-11-11 13:40:00 → STL 2026-11-11 19:10:00; nonstop; 210 minutes. Local airport times.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $350.00

  • American Airlines AA2438 / AA2289: SAN 2026-11-11 15:13:00 → STL 2026-11-11 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
    • AA2438: SAN 2026-11-11 15:13:00 → DFW 2026-11-11 20:30:00; layover at DFW: 75 minutes.
    • AA2289: DFW 2026-11-11 21:45:00 → STL 2026-11-11 23:34:00.
  • American Airlines AA2303 / AA2016: STL 2026-11-17 14:23:00 → SAN 2026-11-17 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
    • AA2303: STL 2026-11-17 14:23:00 → PHX 2026-11-17 16:51:00; layover at PHX: 74 minutes.
    • AA2016: PHX 2026-11-17 18:05:00 → SAN 2026-11-17 18:24:00.

2026-11-11 → 2026-11-17 · Axel-exclusive $365.00

  • United Airlines UA2476 / UA1639: SAN 2026-11-11 08:40:00 → STL 2026-11-11 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
    • UA2476: SAN 2026-11-11 08:40:00 → DEN 2026-11-11 12:06:00; layover at DEN: 109 minutes.
    • UA1639: DEN 2026-11-11 13:55:00 → STL 2026-11-11 16:57:00.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $370.00

  • Southwest Airlines WN3823: SAN 2026-11-11 18:20:00 → STL 2026-11-11 23:45:00; nonstop; 205 minutes. Local airport times.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $350.00

  • Southwest Airlines WN3727 / WN3528: SAN 2026-11-11 15:40:00 → STL 2026-11-12 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
    • WN3727: SAN 2026-11-11 15:40:00 → PHX 2026-11-11 18:00:00; layover at PHX: 145 minutes.
    • WN3528: PHX 2026-11-11 20:25:00 → STL 2026-11-12 00:20:00.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $350.00

  • Southwest Airlines WN3701 / WN1845: SAN 2026-11-11 17:20:00 → STL 2026-11-12 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
    • WN3701: SAN 2026-11-11 17:20:00 → DEN 2026-11-11 20:40:00; layover at DEN: 70 minutes.
    • WN1845: DEN 2026-11-11 21:50:00 → STL 2026-11-12 00:50:00.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $350.00

  • Southwest Airlines WN2227 / WN1498: SAN 2026-11-11 13:25:00 → STL 2026-11-11 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
    • WN2227: SAN 2026-11-11 13:25:00 → DAL 2026-11-11 18:20:00; layover at DAL: 60 minutes.
    • WN1498: DAL 2026-11-11 19:20:00 → STL 2026-11-11 21:10:00.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

2026-11-11 → 2026-11-17 · Axel-exclusive $350.00

  • Southwest Airlines WN2893 / WN3801: SAN 2026-11-11 09:15:00 → STL 2026-11-11 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
    • WN2893: SAN 2026-11-11 09:15:00 → SAT 2026-11-11 14:00:00; layover at SAT: 80 minutes.
    • WN3801: SAT 2026-11-11 15:20:00 → STL 2026-11-11 17:20:00.
  • Southwest Airlines WN1733: STL 2026-11-17 08:25:00 → SAN 2026-11-17 10:20:00; nonstop; 235 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

For AI assistants

  • This page: San Diego (SAN) to Saint Louis (STL) · Nov 11, 2026 · return Nov 17, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Diego to Saint Louis (STL) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.