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San Diego → Panama City

Dec 21, 2026 · return Jan 4, 2027

SAN → PTY1 adulteconomyRound trip

7 flight options · 4 airlines

Nonstop flights

Mon, Dec 21 – Mon, Jan 4

Copa Airlines
10:30 pmSAN
6h 10m
Nonstop
7:40 am+1PTY
Copa Airlines
1:45 pmPTY
6h 37m
Nonstop
5:22 pmSAN

Round-trip total · 1 adult · Taxes included

One-stop flights

Mon, Dec 21 – Mon, Jan 4

American Airlines
10:45 pmSAN
11h 56m
MIA · 3h 43m
1:41 pm+1PTY
American Airlines
2:41 pmPTY
12h 18m
MIA · 3h 25m
11:59 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

United Airlines
10:30 pmSAN
12h 30m
ORD · 2h 53m
2:00 pm+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

Delta Air Lines
8:00 amSAN
10h 45m
ATL · 2h 27m
9:45 pmPTY
Delta Air Lines
3:28 pmPTY
11h 12m
ATL · 2h 1m
11:40 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

United Airlines
6:20 amSAN
11h 19m
LAX · 3h 39m
8:39 pmPTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

United Airlines
4:18 pmSAN
10h 15m
DEN · 2h 5m
5:33 am+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Mon, Jan 4

United Airlines
9:45 pmSAN
12h 46m
IAD · 2h 58m
1:31 pm+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Make this trip yours

SAN ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
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  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2027-01-04Copa AirlinesCM850 / CM847$911.262026-10-29T01:10:05Z
2026-12-21 → 2027-01-04American AirlinesAA3304 + AA315 / AA354 + AA1120$762.762026-10-29T01:10:05Z
2026-12-21 → 2027-01-04United AirlinesUA540 + CM236 / UA1249 + UA2212$789.762026-10-29T01:10:05Z
2026-12-21 → 2027-01-04Delta Air LinesDL1179 + DL1905 / DL1758 + DL896$803.262026-10-29T01:10:05Z
2026-12-21 → 2027-01-04United AirlinesUA1329 + CM402 / UA1249 + UA2212$789.762026-10-29T01:10:05Z
2026-12-21 → 2027-01-04United AirlinesUA682 + CM477 / UA1249 + UA2212$789.762026-10-29T01:10:05Z
2026-12-21 → 2027-01-04United AirlinesUA1577 + CM357 / UA1249 + UA2212$789.762026-10-29T01:10:05Z

2026-12-21 → 2027-01-04 · $911.26

  • Copa Airlines CM850: SAN 2026-12-21 22:30:00 → PTY 2026-12-22 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2027-01-04 13:45:00 → SAN 2027-01-04 17:22:00; nonstop; 397 minutes. Local airport times.

2026-12-21 → 2027-01-04 · $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-21 22:45:00 → PTY 2026-12-22 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-21 22:45:00 → MIA 2026-12-22 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-22 10:27:00 → PTY 2026-12-22 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2027-01-04 14:41:00 → SAN 2027-01-04 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2027-01-04 14:41:00 → MIA 2027-01-04 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2027-01-04 21:20:00 → SAN 2027-01-04 23:59:00.

2026-12-21 → 2027-01-04 · $789.76

  • United Airlines UA540 / CM236: SAN 2026-12-21 22:30:00 → PTY 2026-12-22 14:00:00; 1 stop(s) via ORD; 750 minutes. Local airport times.
    • UA540: SAN 2026-12-21 22:30:00 → ORD 2026-12-22 04:42:00; layover at ORD: 173 minutes.
    • CM236: ORD 2026-12-22 07:35:00 → PTY 2026-12-22 14:00:00.
  • United Airlines UA1249 / UA2212: PTY 2027-01-04 08:55:00 → SAN 2027-01-04 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2027-01-04 08:55:00 → IAH 2027-01-04 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2027-01-04 14:25:00 → SAN 2027-01-04 15:54:00.

2026-12-21 → 2027-01-04 · $803.26

  • Delta Air Lines DL1179 / DL1905: SAN 2026-12-21 08:00:00 → PTY 2026-12-21 21:45:00; 1 stop(s) via ATL; 645 minutes. Local airport times.
    • DL1179: SAN 2026-12-21 08:00:00 → ATL 2026-12-21 15:16:00; layover at ATL: 147 minutes.
    • DL1905: ATL 2026-12-21 17:43:00 → PTY 2026-12-21 21:45:00.
  • Delta Air Lines DL1758 / DL896: PTY 2027-01-04 15:28:00 → SAN 2027-01-04 23:40:00; 1 stop(s) via ATL; 672 minutes. Local airport times.
    • DL1758: PTY 2027-01-04 15:28:00 → ATL 2027-01-04 19:49:00; layover at ATL: 121 minutes.
    • DL896: ATL 2027-01-04 21:50:00 → SAN 2027-01-04 23:40:00.

2026-12-21 → 2027-01-04 · $789.76

  • United Airlines UA1329 / CM402: SAN 2026-12-21 06:20:00 → PTY 2026-12-21 20:39:00; 1 stop(s) via LAX; 679 minutes. Local airport times.
    • UA1329: SAN 2026-12-21 06:20:00 → LAX 2026-12-21 07:25:00; layover at LAX: 219 minutes.
    • CM402: LAX 2026-12-21 11:04:00 → PTY 2026-12-21 20:39:00.
  • United Airlines UA1249 / UA2212: PTY 2027-01-04 08:55:00 → SAN 2027-01-04 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2027-01-04 08:55:00 → IAH 2027-01-04 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2027-01-04 14:25:00 → SAN 2027-01-04 15:54:00.

2026-12-21 → 2027-01-04 · $789.76

  • United Airlines UA682 / CM477: SAN 2026-12-21 16:18:00 → PTY 2026-12-22 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
    • UA682: SAN 2026-12-21 16:18:00 → DEN 2026-12-21 19:45:00; layover at DEN: 125 minutes.
    • CM477: DEN 2026-12-21 21:50:00 → PTY 2026-12-22 05:33:00.
  • United Airlines UA1249 / UA2212: PTY 2027-01-04 08:55:00 → SAN 2027-01-04 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2027-01-04 08:55:00 → IAH 2027-01-04 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2027-01-04 14:25:00 → SAN 2027-01-04 15:54:00.

2026-12-21 → 2027-01-04 · $789.76

  • United Airlines UA1577 / CM357: SAN 2026-12-21 21:45:00 → PTY 2026-12-22 13:31:00; 1 stop(s) via IAD; 766 minutes. Local airport times.
    • UA1577: SAN 2026-12-21 21:45:00 → IAD 2026-12-22 05:27:00; layover at IAD: 178 minutes.
    • CM357: IAD 2026-12-22 08:25:00 → PTY 2026-12-22 13:31:00.
  • United Airlines UA1249 / UA2212: PTY 2027-01-04 08:55:00 → SAN 2027-01-04 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2027-01-04 08:55:00 → IAH 2027-01-04 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2027-01-04 14:25:00 → SAN 2027-01-04 15:54:00.

More dates for this route