Fort Myers (RSW) to Saint Louis (STL), Nov 18–25, 2026: from $364 round trip

Fort Myers (RSW) to Saint Louis (STL), Nov 18–25, 2026: from $364 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $364 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 18–25, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 18–25, 2026 · 7 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $472 total · 4★ Hilton St. Louis at the Ballpark, $726 total · 5★ Four Seasons Hotel St Louis, $2,562 total

All hotels in St. Louis

Route overview: Fort Myers to Saint Louis (STL) flight deals

2026-11-18 → 2026-11-25 · Axel-exclusive $399.50

• Southwest Airlines WN3678: RSW 2026-11-18 05:40:00 → STL 2026-11-18 07:15:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN4196: STL 2026-11-25 19:55:00 → RSW 2026-11-25 23:20:00; nonstop; 145 minutes. Local airport times.

2026-11-18 → 2026-11-25 · Axel-exclusive $394.25

• American Airlines AA2515 / AA2486: RSW 2026-11-18 06:00:00 → STL 2026-11-18 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
  • AA2515: RSW 2026-11-18 06:00:00 → CLT 2026-11-18 08:03:00; layover at CLT: 72 minutes.
  • AA2486: CLT 2026-11-18 09:15:00 → STL 2026-11-18 10:19:00.
• Southwest Airlines WN287 / WN2097: STL 2026-11-25 10:55:00 → RSW 2026-11-25 17:00:00; 1 stop(s) via MDW; 305 minutes. Local airport times.
  • WN287: STL 2026-11-25 10:55:00 → MDW 2026-11-25 12:05:00; layover at MDW: 70 minutes.
  • WN2097: MDW 2026-11-25 13:15:00 → RSW 2026-11-25 17:00:00.

2026-11-18 → 2026-11-25 · Axel-exclusive $446.50

• United Airlines UA2347 / UA4619: RSW 2026-11-18 09:05:00 → STL 2026-11-18 14:18:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
  • UA2347: RSW 2026-11-18 09:05:00 → ORD 2026-11-18 11:24:00; layover at ORD: 86 minutes.
  • UA4619: ORD 2026-11-18 12:50:00 → STL 2026-11-18 14:18:00.
• United Airlines UA4406 / UA2660: STL 2026-11-25 08:30:00 → RSW 2026-11-25 15:27:00; 1 stop(s) via IAD; 357 minutes. Local airport times.
  • UA4406: STL 2026-11-25 08:30:00 → IAD 2026-11-25 11:35:00; layover at IAD: 60 minutes.
  • UA2660: IAD 2026-11-25 12:35:00 → RSW 2026-11-25 15:27:00.

2026-11-18 → 2026-11-25 · Axel-exclusive $464.13

• Delta Air Lines DL1395 / DL1102: RSW 2026-11-18 08:00:00 → STL 2026-11-18 13:28:00; 1 stop(s) via ATL; 388 minutes. Local airport times.
  • DL1395: RSW 2026-11-18 08:00:00 → ATL 2026-11-18 09:55:00; layover at ATL: 169 minutes.
  • DL1102: ATL 2026-11-18 12:44:00 → STL 2026-11-18 13:28:00.
• Delta Air Lines DL1393 / DL1217: STL 2026-11-25 19:18:00 → RSW 2026-11-26 00:40:00; 1 stop(s) via ATL; 262 minutes. Local airport times.
  • DL1393: STL 2026-11-25 19:18:00 → ATL 2026-11-25 21:59:00; layover at ATL: 60 minutes.
  • DL1217: ATL 2026-11-25 22:59:00 → RSW 2026-11-26 00:40:00.

2026-11-18 → 2026-11-25 · Axel-exclusive $399.50

• Southwest Airlines WN3678: RSW 2026-11-18 06:05:00 → STL 2026-11-18 07:40:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN2652: STL 2026-11-25 09:50:00 → RSW 2026-11-25 13:15:00; nonstop; 145 minutes. Local airport times.

2026-11-18 → 2026-11-25 · Axel-exclusive $364.25

• Southwest Airlines WN166 / WN4782: RSW 2026-11-18 19:15:00 → STL 2026-11-19 00:40:00; 1 stop(s) via HOU; 385 minutes. Local airport times.
  • WN166: RSW 2026-11-18 19:15:00 → HOU 2026-11-18 20:50:00; layover at HOU: 105 minutes.
  • WN4782: HOU 2026-11-18 22:35:00 → STL 2026-11-19 00:40:00.
• Southwest Airlines WN287 / WN2097: STL 2026-11-25 10:55:00 → RSW 2026-11-25 17:00:00; 1 stop(s) via MDW; 305 minutes. Local airport times.
  • WN287: STL 2026-11-25 10:55:00 → MDW 2026-11-25 12:05:00; layover at MDW: 70 minutes.
  • WN2097: MDW 2026-11-25 13:15:00 → RSW 2026-11-25 17:00:00.

2026-11-18 → 2026-11-25 · Axel-exclusive $379.25

• Southwest Airlines WN3678: RSW 2026-11-18 06:00:00 → STL 2026-11-18 07:40:00; nonstop; 160 minutes. Local airport times.
• Southwest Airlines WN287 / WN2097: STL 2026-11-25 10:55:00 → RSW 2026-11-25 17:00:00; 1 stop(s) via MDW; 305 minutes. Local airport times.
  • WN287: STL 2026-11-25 10:55:00 → MDW 2026-11-25 12:05:00; layover at MDW: 70 minutes.
  • WN2097: MDW 2026-11-25 13:15:00 → RSW 2026-11-25 17:00:00.

2026-11-18 → 2026-11-25 · Axel-exclusive $394.25

• American Airlines AA3052 / AA2246: RSW 2026-11-18 14:34:00 → STL 2026-11-18 19:36:00; 1 stop(s) via DFW; 362 minutes. Local airport times.
  • AA3052: RSW 2026-11-18 14:34:00 → DFW 2026-11-18 16:49:00; layover at DFW: 66 minutes.
  • AA2246: DFW 2026-11-18 17:55:00 → STL 2026-11-18 19:36:00.
• Southwest Airlines WN287 / WN2097: STL 2026-11-25 10:55:00 → RSW 2026-11-25 17:00:00; 1 stop(s) via MDW; 305 minutes. Local airport times.
  • WN287: STL 2026-11-25 10:55:00 → MDW 2026-11-25 12:05:00; layover at MDW: 70 minutes.
  • WN2097: MDW 2026-11-25 13:15:00 → RSW 2026-11-25 17:00:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 17, 2026 · Return options
• Nov 19, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Fort Myers (RSW) to Saint Louis (STL) · Nov 18, 2026 · return Nov 25, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
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