Travel with Axel,
get the best price.

Fort Myers → Saint Louis

Choose your travel dates

RSW → STL1 adulteconomy

24 flight options · 4 airlines

Round-trip flights

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:15 pmRSW
2h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
6:00 amRSW
5h 19m
CLT · 1h 12m
10:19 amSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
9:05 amRSW
6h 13m
ORD · 1h 26m
2:18 pmSTL
United Airlines
8:30 amSTL
5h 57m
IAD · 1h
3:27 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
8:00 amRSW
6h 28m
ATL · 2h 49m
1:28 pmSTL
Delta Air Lines
7:18 pmSTL
4h 22m
ATL · 1h
12:40 am+1RSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
6:10 amRSW
2h 35m
Nonstop
7:45 amSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
6:10 amRSW
2h 35m
Nonstop
7:45 amSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:15 pmRSW
2h 45m
Nonstop
9:00 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:20 pmRSW
5h 35m
BNA · 2h
11:55 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Show 8 more flights

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:15 pmRSW
6h 25m
HOU · 1h 45m
12:40 am+1STL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
2:34 pmRSW
6h 2m
DFW · 1h 6m
7:36 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:20 pmRSW
5h 35m
BNA · 2h
11:55 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:15 pmRSW
6h 25m
HOU · 1h 45m
12:40 am+1STL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
6:00 amRSW
5h 19m
CLT · 1h 12m
10:19 amSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
2:34 pmRSW
6h 2m
DFW · 1h 6m
7:36 pmSTL
Southwest Airlines
2:20 pmSTL
2h 25m
Nonstop
5:45 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
9:05 amRSW
6h 13m
ORD · 1h 26m
2:18 pmSTL
United Airlines
8:30 amSTL
5h 57m
IAD · 1h
3:27 pmRSW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
8:00 amRSW
6h 28m
ATL · 2h 49m
1:28 pmSTL
Delta Air Lines
7:18 pmSTL
4h 22m
ATL · 1h
12:40 am+1RSW

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Southwest Airlines
6:10 amRSW
2h 35m
Nonstop
7:45 amSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
6:00 amRSW
5h 19m
CLT · 1h 12m
10:19 amSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
9:05 amRSW
6h 13m
ORD · 1h 26m
2:18 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
8:00 amRSW
6h 28m
ATL · 2h 49m
1:28 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
7:15 pmRSW
2h 45m
Nonstop
9:00 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
7:15 pmRSW
6h 25m
HOU · 1h 45m
12:40 am+1STL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
7:20 pmRSW
5h 35m
BNA · 2h
11:55 pmSTL

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
2:34 pmRSW
6h 2m
DFW · 1h 6m
7:36 pmSTL

One-way total · 1 adult · Taxes included

Make this trip yours

RSW ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one waySouthwest AirlinesWN3678$180.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3680 / WN4149$340.002026-10-29T01:07:56Z
2026-11-20 · one wayAmerican AirlinesAA2515 + AA2486$195.002026-10-29T01:07:56Z
2026-11-20 · one wayUnited AirlinesUA2347 + UA4619$200.002026-10-29T01:07:56Z
2026-11-20 · one wayDelta Air LinesDL1395 + DL1102$210.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23American Airlines / Southwest AirlinesAA2515 + AA2486 / WN4149$355.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23United AirlinesUA2347 + UA4619 / UA4406 + UA2660$380.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23Delta Air LinesDL1395 + DL1102 / DL1393 + DL1217$395.002026-10-29T01:07:56Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3678 / WN4149$399.502026-10-29T01:07:56Z
2026-11-20 · one waySouthwest AirlinesWN3680$180.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3678 / WN4149$340.002026-10-29T01:07:56Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3680 / WN4149$399.502026-10-29T01:07:56Z
2026-11-20 · one waySouthwest AirlinesWN166 + WN4782$165.002026-10-29T01:07:56Z
2026-11-20 · one waySouthwest AirlinesWN3655 + WN2043$165.002026-10-29T01:07:56Z
2026-11-20 · one wayAmerican AirlinesAA3052 + AA2246$195.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23Southwest AirlinesWN3655 + WN2043 / WN4149$325.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23Southwest AirlinesWN166 + WN4782 / WN4149$325.002026-10-29T01:07:56Z
2026-11-20 → 2026-11-23American Airlines / Southwest AirlinesAA3052 + AA2246 / WN4149$355.002026-10-29T01:07:56Z
2026-11-27 → 2026-12-04Southwest AirlinesWN3655 + WN2043 / WN4149$379.252026-10-29T01:07:56Z
2026-11-27 → 2026-12-04Southwest AirlinesWN166 + WN4782 / WN4149$379.252026-10-29T01:07:56Z
2026-11-27 → 2026-12-04American Airlines / Southwest AirlinesAA2515 + AA2486 / WN4149$419.752026-10-29T01:07:56Z
2026-11-27 → 2026-12-04American Airlines / Southwest AirlinesAA3052 + AA2246 / WN4149$419.752026-10-29T01:07:56Z
2026-11-27 → 2026-12-04United AirlinesUA2347 + UA4619 / UA4406 + UA2660$446.502026-10-29T01:07:56Z
2026-11-27 → 2026-12-04Delta Air LinesDL1395 + DL1102 / DL1393 + DL1217$464.132026-10-29T01:07:56Z

2026-11-20 · one way · $180.00

  • Southwest Airlines WN3678: RSW 2026-11-20 06:10:00 → STL 2026-11-20 07:45:00; nonstop; 155 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $340.00

  • Southwest Airlines WN3680: RSW 2026-11-20 19:15:00 → STL 2026-11-20 21:00:00; nonstop; 165 minutes. Local airport times.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 · one way · $195.00

  • American Airlines AA2515 / AA2486: RSW 2026-11-20 06:00:00 → STL 2026-11-20 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
    • AA2515: RSW 2026-11-20 06:00:00 → CLT 2026-11-20 08:03:00; layover at CLT: 72 minutes.
    • AA2486: CLT 2026-11-20 09:15:00 → STL 2026-11-20 10:19:00.

2026-11-20 · one way · $200.00

  • United Airlines UA2347 / UA4619: RSW 2026-11-20 09:05:00 → STL 2026-11-20 14:18:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
    • UA2347: RSW 2026-11-20 09:05:00 → ORD 2026-11-20 11:24:00; layover at ORD: 86 minutes.
    • UA4619: ORD 2026-11-20 12:50:00 → STL 2026-11-20 14:18:00.

2026-11-20 · one way · $210.00

  • Delta Air Lines DL1395 / DL1102: RSW 2026-11-20 08:00:00 → STL 2026-11-20 13:28:00; 1 stop(s) via ATL; 388 minutes. Local airport times.
    • DL1395: RSW 2026-11-20 08:00:00 → ATL 2026-11-20 09:55:00; layover at ATL: 169 minutes.
    • DL1102: ATL 2026-11-20 12:44:00 → STL 2026-11-20 13:28:00.

2026-11-20 → 2026-11-23 · $355.00

  • American Airlines AA2515 / AA2486: RSW 2026-11-20 06:00:00 → STL 2026-11-20 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
    • AA2515: RSW 2026-11-20 06:00:00 → CLT 2026-11-20 08:03:00; layover at CLT: 72 minutes.
    • AA2486: CLT 2026-11-20 09:15:00 → STL 2026-11-20 10:19:00.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $380.00

  • United Airlines UA2347 / UA4619: RSW 2026-11-20 09:05:00 → STL 2026-11-20 14:18:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
    • UA2347: RSW 2026-11-20 09:05:00 → ORD 2026-11-20 11:24:00; layover at ORD: 86 minutes.
    • UA4619: ORD 2026-11-20 12:50:00 → STL 2026-11-20 14:18:00.
  • United Airlines UA4406 / UA2660: STL 2026-11-23 08:30:00 → RSW 2026-11-23 15:27:00; 1 stop(s) via IAD; 357 minutes. Local airport times.
    • UA4406: STL 2026-11-23 08:30:00 → IAD 2026-11-23 11:35:00; layover at IAD: 60 minutes.
    • UA2660: IAD 2026-11-23 12:35:00 → RSW 2026-11-23 15:27:00.

2026-11-20 → 2026-11-23 · $395.00

  • Delta Air Lines DL1395 / DL1102: RSW 2026-11-20 08:00:00 → STL 2026-11-20 13:28:00; 1 stop(s) via ATL; 388 minutes. Local airport times.
    • DL1395: RSW 2026-11-20 08:00:00 → ATL 2026-11-20 09:55:00; layover at ATL: 169 minutes.
    • DL1102: ATL 2026-11-20 12:44:00 → STL 2026-11-20 13:28:00.
  • Delta Air Lines DL1393 / DL1217: STL 2026-11-23 19:18:00 → RSW 2026-11-24 00:40:00; 1 stop(s) via ATL; 262 minutes. Local airport times.
    • DL1393: STL 2026-11-23 19:18:00 → ATL 2026-11-23 21:59:00; layover at ATL: 60 minutes.
    • DL1217: ATL 2026-11-23 22:59:00 → RSW 2026-11-24 00:40:00.

2026-11-27 → 2026-12-04 · $399.50

  • Southwest Airlines WN3678: RSW 2026-11-27 06:10:00 → STL 2026-11-27 07:45:00; nonstop; 155 minutes. Local airport times.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 · one way · $180.00

  • Southwest Airlines WN3680: RSW 2026-11-20 19:15:00 → STL 2026-11-20 21:00:00; nonstop; 165 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $340.00

  • Southwest Airlines WN3678: RSW 2026-11-20 06:10:00 → STL 2026-11-20 07:45:00; nonstop; 155 minutes. Local airport times.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $399.50

  • Southwest Airlines WN3680: RSW 2026-11-27 19:15:00 → STL 2026-11-27 21:00:00; nonstop; 165 minutes. Local airport times.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 · one way · $165.00

  • Southwest Airlines WN166 / WN4782: RSW 2026-11-20 19:15:00 → STL 2026-11-21 00:40:00; 1 stop(s) via HOU; 385 minutes. Local airport times.
    • WN166: RSW 2026-11-20 19:15:00 → HOU 2026-11-20 20:50:00; layover at HOU: 105 minutes.
    • WN4782: HOU 2026-11-20 22:35:00 → STL 2026-11-21 00:40:00.

2026-11-20 · one way · $165.00

  • Southwest Airlines WN3655 / WN2043: RSW 2026-11-20 19:20:00 → STL 2026-11-20 23:55:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
    • WN3655: RSW 2026-11-20 19:20:00 → BNA 2026-11-20 20:40:00; layover at BNA: 120 minutes.
    • WN2043: BNA 2026-11-20 22:40:00 → STL 2026-11-20 23:55:00.

2026-11-20 · one way · $195.00

  • American Airlines AA3052 / AA2246: RSW 2026-11-20 14:34:00 → STL 2026-11-20 19:36:00; 1 stop(s) via DFW; 362 minutes. Local airport times.
    • AA3052: RSW 2026-11-20 14:34:00 → DFW 2026-11-20 16:49:00; layover at DFW: 66 minutes.
    • AA2246: DFW 2026-11-20 17:55:00 → STL 2026-11-20 19:36:00.

2026-11-20 → 2026-11-23 · $325.00

  • Southwest Airlines WN3655 / WN2043: RSW 2026-11-20 19:20:00 → STL 2026-11-20 23:55:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
    • WN3655: RSW 2026-11-20 19:20:00 → BNA 2026-11-20 20:40:00; layover at BNA: 120 minutes.
    • WN2043: BNA 2026-11-20 22:40:00 → STL 2026-11-20 23:55:00.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $325.00

  • Southwest Airlines WN166 / WN4782: RSW 2026-11-20 19:15:00 → STL 2026-11-21 00:40:00; 1 stop(s) via HOU; 385 minutes. Local airport times.
    • WN166: RSW 2026-11-20 19:15:00 → HOU 2026-11-20 20:50:00; layover at HOU: 105 minutes.
    • WN4782: HOU 2026-11-20 22:35:00 → STL 2026-11-21 00:40:00.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $355.00

  • American Airlines AA3052 / AA2246: RSW 2026-11-20 14:34:00 → STL 2026-11-20 19:36:00; 1 stop(s) via DFW; 362 minutes. Local airport times.
    • AA3052: RSW 2026-11-20 14:34:00 → DFW 2026-11-20 16:49:00; layover at DFW: 66 minutes.
    • AA2246: DFW 2026-11-20 17:55:00 → STL 2026-11-20 19:36:00.
  • Southwest Airlines WN4149: STL 2026-11-23 14:20:00 → RSW 2026-11-23 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $379.25

  • Southwest Airlines WN3655 / WN2043: RSW 2026-11-27 19:20:00 → STL 2026-11-27 23:55:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
    • WN3655: RSW 2026-11-27 19:20:00 → BNA 2026-11-27 20:40:00; layover at BNA: 120 minutes.
    • WN2043: BNA 2026-11-27 22:40:00 → STL 2026-11-27 23:55:00.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $379.25

  • Southwest Airlines WN166 / WN4782: RSW 2026-11-27 19:15:00 → STL 2026-11-28 00:40:00; 1 stop(s) via HOU; 385 minutes. Local airport times.
    • WN166: RSW 2026-11-27 19:15:00 → HOU 2026-11-27 20:50:00; layover at HOU: 105 minutes.
    • WN4782: HOU 2026-11-27 22:35:00 → STL 2026-11-28 00:40:00.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $419.75

  • American Airlines AA2515 / AA2486: RSW 2026-11-27 06:00:00 → STL 2026-11-27 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
    • AA2515: RSW 2026-11-27 06:00:00 → CLT 2026-11-27 08:03:00; layover at CLT: 72 minutes.
    • AA2486: CLT 2026-11-27 09:15:00 → STL 2026-11-27 10:19:00.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $419.75

  • American Airlines AA3052 / AA2246: RSW 2026-11-27 14:34:00 → STL 2026-11-27 19:36:00; 1 stop(s) via DFW; 362 minutes. Local airport times.
    • AA3052: RSW 2026-11-27 14:34:00 → DFW 2026-11-27 16:49:00; layover at DFW: 66 minutes.
    • AA2246: DFW 2026-11-27 17:55:00 → STL 2026-11-27 19:36:00.
  • Southwest Airlines WN4149: STL 2026-12-04 14:20:00 → RSW 2026-12-04 17:45:00; nonstop; 145 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $446.50

  • United Airlines UA2347 / UA4619: RSW 2026-11-27 09:05:00 → STL 2026-11-27 14:18:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
    • UA2347: RSW 2026-11-27 09:05:00 → ORD 2026-11-27 11:24:00; layover at ORD: 86 minutes.
    • UA4619: ORD 2026-11-27 12:50:00 → STL 2026-11-27 14:18:00.
  • United Airlines UA4406 / UA2660: STL 2026-12-04 08:30:00 → RSW 2026-12-04 15:27:00; 1 stop(s) via IAD; 357 minutes. Local airport times.
    • UA4406: STL 2026-12-04 08:30:00 → IAD 2026-12-04 11:35:00; layover at IAD: 60 minutes.
    • UA2660: IAD 2026-12-04 12:35:00 → RSW 2026-12-04 15:27:00.

2026-11-27 → 2026-12-04 · $464.13

  • Delta Air Lines DL1395 / DL1102: RSW 2026-11-27 08:00:00 → STL 2026-11-27 13:28:00; 1 stop(s) via ATL; 388 minutes. Local airport times.
    • DL1395: RSW 2026-11-27 08:00:00 → ATL 2026-11-27 09:55:00; layover at ATL: 169 minutes.
    • DL1102: ATL 2026-11-27 12:44:00 → STL 2026-11-27 13:28:00.
  • Delta Air Lines DL1393 / DL1217: STL 2026-12-04 19:18:00 → RSW 2026-12-05 00:40:00; 1 stop(s) via ATL; 262 minutes. Local airport times.
    • DL1393: STL 2026-12-04 19:18:00 → ATL 2026-12-04 21:59:00; layover at ATL: 60 minutes.
    • DL1217: ATL 2026-12-04 22:59:00 → RSW 2026-12-05 00:40:00.

More dates for this route