Fort Myers (RSW) to Saint Louis (STL) · Dec 23, 2026 · return Dec 27, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in St. Louis for these nights (Dec 23–27, 2026 · 4 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $274 total · 4★ Hilton St. Louis at the Ballpark, $412 total · 5★ Four Seasons Hotel St Louis, $1,625 total

All hotels in St. Louis

Route overview: Fort Myers to Saint Louis (STL) flight deals

2026-12-23 → 2026-12-27 · Axel-exclusive $442.00

• Southwest Airlines WN3680: RSW 2026-12-23 19:15:00 → STL 2026-12-23 21:00:00; nonstop; 165 minutes. Local airport times.
• Southwest Airlines WN4195: STL 2026-12-27 16:10:00 → RSW 2026-12-27 19:35:00; nonstop; 145 minutes. Local airport times.

2026-12-23 → 2026-12-27 · Axel-exclusive $461.50

• American Airlines AA2515 / AA2486: RSW 2026-12-23 06:00:00 → STL 2026-12-23 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
  • AA2515: RSW 2026-12-23 06:00:00 → CLT 2026-12-23 08:03:00; layover at CLT: 72 minutes.
  • AA2486: CLT 2026-12-23 09:15:00 → STL 2026-12-23 10:19:00.
• Southwest Airlines WN4195: STL 2026-12-27 16:10:00 → RSW 2026-12-27 19:35:00; nonstop; 145 minutes. Local airport times.

2026-12-23 → 2026-12-27 · Axel-exclusive $494.00

• United Airlines UA2347 / UA4619: RSW 2026-12-23 09:05:00 → STL 2026-12-23 14:18:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
  • UA2347: RSW 2026-12-23 09:05:00 → ORD 2026-12-23 11:24:00; layover at ORD: 86 minutes.
  • UA4619: ORD 2026-12-23 12:50:00 → STL 2026-12-23 14:18:00.
• United Airlines UA4406 / UA2660: STL 2026-12-27 08:30:00 → RSW 2026-12-27 15:27:00; 1 stop(s) via IAD; 357 minutes. Local airport times.
  • UA4406: STL 2026-12-27 08:30:00 → IAD 2026-12-27 11:35:00; layover at IAD: 60 minutes.
  • UA2660: IAD 2026-12-27 12:35:00 → RSW 2026-12-27 15:27:00.

2026-12-23 → 2026-12-27 · Axel-exclusive $513.50

• Delta Air Lines DL1395 / DL1102: RSW 2026-12-23 08:00:00 → STL 2026-12-23 13:28:00; 1 stop(s) via ATL; 388 minutes. Local airport times.
  • DL1395: RSW 2026-12-23 08:00:00 → ATL 2026-12-23 09:55:00; layover at ATL: 169 minutes.
  • DL1102: ATL 2026-12-23 12:44:00 → STL 2026-12-23 13:28:00.
• Delta Air Lines DL1393 / DL1217: STL 2026-12-27 19:18:00 → RSW 2026-12-28 00:40:00; 1 stop(s) via ATL; 262 minutes. Local airport times.
  • DL1393: STL 2026-12-27 19:18:00 → ATL 2026-12-27 21:59:00; layover at ATL: 60 minutes.
  • DL1217: ATL 2026-12-27 22:59:00 → RSW 2026-12-28 00:40:00.

2026-12-23 → 2026-12-27 · Axel-exclusive $442.00

• Southwest Airlines WN3678: RSW 2026-12-23 05:40:00 → STL 2026-12-23 07:15:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN4195: STL 2026-12-27 16:10:00 → RSW 2026-12-27 19:35:00; nonstop; 145 minutes. Local airport times.

2026-12-23 → 2026-12-27 · Axel-exclusive $422.50

• Southwest Airlines WN3678: RSW 2026-12-23 06:10:00 → STL 2026-12-23 07:45:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN4170 / WN2937: STL 2026-12-27 16:20:00 → RSW 2026-12-27 21:55:00; 1 stop(s) via MCO; 275 minutes. Local airport times.
  • WN4170: STL 2026-12-27 16:20:00 → MCO 2026-12-27 19:40:00; layover at MCO: 65 minutes.
  • WN2937: MCO 2026-12-27 20:45:00 → RSW 2026-12-27 21:55:00.

2026-12-23 → 2026-12-27 · Axel-exclusive $422.50

• Southwest Airlines WN3655 / WN2043: RSW 2026-12-23 19:20:00 → STL 2026-12-23 23:55:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
  • WN3655: RSW 2026-12-23 19:20:00 → BNA 2026-12-23 20:40:00; layover at BNA: 120 minutes.
  • WN2043: BNA 2026-12-23 22:40:00 → STL 2026-12-23 23:55:00.
• Southwest Airlines WN4195: STL 2026-12-27 16:10:00 → RSW 2026-12-27 19:35:00; nonstop; 145 minutes. Local airport times.

2026-12-23 → 2026-12-27 · Axel-exclusive $422.50

• Southwest Airlines WN166 / WN4782: RSW 2026-12-23 19:15:00 → STL 2026-12-24 00:40:00; 1 stop(s) via HOU; 385 minutes. Local airport times.
  • WN166: RSW 2026-12-23 19:15:00 → HOU 2026-12-23 20:50:00; layover at HOU: 105 minutes.
  • WN4782: HOU 2026-12-23 22:35:00 → STL 2026-12-24 00:40:00.
• Southwest Airlines WN4195: STL 2026-12-27 16:10:00 → RSW 2026-12-27 19:35:00; nonstop; 145 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 22, 2026 · Return options
• Dec 24, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Fort Myers (RSW) to Saint Louis (STL) · Dec 23, 2026 · return Dec 27, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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