Raleigh/Durham (RDU) to Panama City (PTY), Jan 3, 2027: round trips from $546, one way from $344

Raleigh/Durham (RDU) to Panama City (PTY), Jan 3, 2027: round trips from $546, one way from $344 on Axel, checked Oct 29, 2026. Lowest published fares: $546 round trip, Axel-exclusive, American Airlines, 1 stop, Jan 3–6, 2027; $344 one way, Axel-exclusive, American Airlines, 1 stop, Jan 3, 2027; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Panama City for these nights (Jan 3–4, 2027 · 1 night · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $58 total · 4★ Hospedium Princess Hotel Panama, $45 total · 5★ Renaissance Panama City Hotel, $122 total
• Hotels in Panama City for these nights (Jan 3–5, 2027 · 2 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $118 total · 4★ Hospedium Princess Hotel Panama, $91 total · 5★ Renaissance Panama City Hotel, $236 total
• Hotels in Panama City for these nights (Jan 3–6, 2027 · 3 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $178 total · 4★ Hospedium Princess Hotel Panama, $137 total · 5★ Renaissance Panama City Hotel, $358 total
• Hotels in Panama City for these nights (Jan 3–7, 2027 · 4 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $236 total · 4★ Hospedium Princess Hotel Panama, $182 total · 5★ Renaissance Panama City Hotel, $496 total
• Hotels in Panama City for these nights (Jan 3–8, 2027 · 5 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $295 total · 4★ Hospedium Princess Hotel Panama, $228 total · 5★ Renaissance Panama City Hotel, $651 total
• Hotels in Panama City for these nights (Jan 3–9, 2027 · 6 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $354 total · 4★ Hospedium Princess Hotel Panama, $277 total · 5★ Renaissance Panama City Hotel, $814 total
• Hotels in Panama City for these nights (Jan 3–10, 2027 · 7 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $413 total · 4★ Hospedium Princess Hotel Panama, $326 total · 5★ Renaissance Panama City Hotel, $961 total
• Hotels in Panama City for these nights (Jan 3–11, 2027 · 8 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $472 total · 4★ Hospedium Princess Hotel Panama, $375 total · 5★ Renaissance Panama City Hotel, $1,116 total
• Hotels in Panama City for these nights (Jan 3–12, 2027 · 9 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $531 total · 4★ Hospedium Princess Hotel Panama, $421 total · 5★ Renaissance Panama City Hotel, $1,279 total
• Hotels in Panama City for these nights (Jan 3–13, 2027 · 10 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $590 total · 4★ Hospedium Princess Hotel Panama, $467 total · 5★ Renaissance Panama City Hotel, $1,434 total
• Hotels in Panama City for these nights (Jan 3–14, 2027 · 11 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $650 total · 4★ Hospedium Princess Hotel Panama, $513 total · 5★ Renaissance Panama City Hotel, $1,581 total
• Hotels in Panama City for these nights (Jan 3–15, 2027 · 12 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $708 total · 4★ Hospedium Princess Hotel Panama, $559 total · 5★ Renaissance Panama City Hotel, $1,736 total
• Hotels in Panama City for these nights (Jan 3–16, 2027 · 13 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $768 total · 4★ Hospedium Princess Hotel Panama, $605 total · 5★ Renaissance Panama City Hotel, $1,907 total
• Hotels in Panama City for these nights (Jan 3–17, 2027 · 14 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $826 total · 4★ Hospedium Princess Hotel Panama, $654 total · 5★ Renaissance Panama City Hotel, $2,070 total

All hotels in Panama City

Route overview: Raleigh/Durham to Panama City (PTY) flight deals

2027-01-03 · one way · Axel-exclusive $344.25

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.

2027-01-03 · one way · Axel-exclusive $384.75

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.

2027-01-03 → 2027-01-04 · Axel-exclusive $627.76

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-04 14:26:00 → RDU 2027-01-04 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-04 14:26:00 → MIA 2027-01-04 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-04 19:40:00 → RDU 2027-01-04 22:04:00.

2027-01-03 → 2027-01-04 · Axel-exclusive $695.26

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-04 08:57:00 → RDU 2027-01-04 13:16:00; nonstop; 259 minutes. Local airport times.

2027-01-03 → 2027-01-05 · Axel-exclusive $627.76

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-05 14:26:00 → RDU 2027-01-05 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-05 14:26:00 → MIA 2027-01-05 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-05 19:40:00 → RDU 2027-01-05 22:04:00.

2027-01-03 → 2027-01-05 · Axel-exclusive $695.26

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-05 08:57:00 → RDU 2027-01-05 13:21:00; nonstop; 264 minutes. Local airport times.

2027-01-03 → 2027-01-06 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-06 14:26:00 → RDU 2027-01-06 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-06 14:26:00 → MIA 2027-01-06 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-06 19:40:00 → RDU 2027-01-06 22:04:00.

2027-01-03 → 2027-01-06 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-06 08:57:00 → RDU 2027-01-06 13:16:00; nonstop; 259 minutes. Local airport times.

2027-01-03 → 2027-01-07 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-07 14:26:00 → RDU 2027-01-07 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-07 14:26:00 → MIA 2027-01-07 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-07 19:40:00 → RDU 2027-01-07 22:04:00.

2027-01-03 → 2027-01-07 · Axel-exclusive $569.88

• United Airlines UA1536 / UA1021: RDU 2027-01-03 11:24:00 → PTY 2027-01-03 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
  • UA1536: RDU 2027-01-03 11:24:00 → EWR 2027-01-03 13:29:00; layover at EWR: 78 minutes.
  • UA1021: EWR 2027-01-03 14:47:00 → PTY 2027-01-03 20:02:00.
• United Airlines UA1703 / UA1890: PTY 2027-01-07 23:55:00 → RDU 2027-01-08 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
  • UA1703: PTY 2027-01-07 23:55:00 → EWR 2027-01-08 04:56:00; layover at EWR: 154 minutes.
  • UA1890: EWR 2027-01-08 07:30:00 → RDU 2027-01-08 09:15:00.

2027-01-03 → 2027-01-09 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-09 14:26:00 → RDU 2027-01-09 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-09 14:26:00 → MIA 2027-01-09 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-09 19:40:00 → RDU 2027-01-09 22:04:00.

2027-01-03 → 2027-01-09 · Axel-exclusive $569.88

• United Airlines UA1536 / UA1021: RDU 2027-01-03 11:24:00 → PTY 2027-01-03 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
  • UA1536: RDU 2027-01-03 11:24:00 → EWR 2027-01-03 13:29:00; layover at EWR: 78 minutes.
  • UA1021: EWR 2027-01-03 14:47:00 → PTY 2027-01-03 20:02:00.
• United Airlines UA1703 / UA1890: PTY 2027-01-09 23:55:00 → RDU 2027-01-10 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
  • UA1703: PTY 2027-01-09 23:55:00 → EWR 2027-01-10 04:56:00; layover at EWR: 154 minutes.
  • UA1890: EWR 2027-01-10 07:30:00 → RDU 2027-01-10 09:15:00.

2027-01-03 → 2027-01-10 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-10 14:26:00 → RDU 2027-01-10 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-10 14:26:00 → MIA 2027-01-10 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-10 19:40:00 → RDU 2027-01-10 22:04:00.

2027-01-03 → 2027-01-10 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-10 08:57:00 → RDU 2027-01-10 13:21:00; nonstop; 264 minutes. Local airport times.

2027-01-03 → 2027-01-11 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-11 14:26:00 → RDU 2027-01-11 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-11 14:26:00 → MIA 2027-01-11 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-11 19:40:00 → RDU 2027-01-11 22:04:00.

2027-01-03 → 2027-01-11 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-11 08:57:00 → RDU 2027-01-11 13:16:00; nonstop; 259 minutes. Local airport times.

2027-01-03 → 2027-01-13 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-13 14:26:00 → RDU 2027-01-13 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-13 14:26:00 → MIA 2027-01-13 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-13 19:40:00 → RDU 2027-01-13 22:04:00.

2027-01-03 → 2027-01-13 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-13 08:57:00 → RDU 2027-01-13 13:16:00; nonstop; 259 minutes. Local airport times.

2027-01-03 → 2027-01-14 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-14 14:26:00 → RDU 2027-01-14 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-14 14:26:00 → MIA 2027-01-14 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-14 19:40:00 → RDU 2027-01-14 22:04:00.

2027-01-03 → 2027-01-14 · Axel-exclusive $569.88

• United Airlines UA1536 / UA1021: RDU 2027-01-03 11:24:00 → PTY 2027-01-03 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
  • UA1536: RDU 2027-01-03 11:24:00 → EWR 2027-01-03 13:29:00; layover at EWR: 78 minutes.
  • UA1021: EWR 2027-01-03 14:47:00 → PTY 2027-01-03 20:02:00.
• United Airlines UA1703 / UA1890: PTY 2027-01-14 23:55:00 → RDU 2027-01-15 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
  • UA1703: PTY 2027-01-14 23:55:00 → EWR 2027-01-15 04:56:00; layover at EWR: 154 minutes.
  • UA1890: EWR 2027-01-15 07:30:00 → RDU 2027-01-15 09:15:00.

2027-01-03 → 2027-01-15 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-15 14:26:00 → RDU 2027-01-15 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-15 14:26:00 → MIA 2027-01-15 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-15 19:40:00 → RDU 2027-01-15 22:04:00.

2027-01-03 → 2027-01-15 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-15 08:57:00 → RDU 2027-01-15 13:21:00; nonstop; 264 minutes. Local airport times.

2027-01-03 → 2027-01-17 · Axel-exclusive $546.38

• American Airlines AA1088 / AA2177: RDU 2027-01-03 07:00:00 → PTY 2027-01-03 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-03 07:00:00 → MIA 2027-01-03 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-03 12:17:00 → PTY 2027-01-03 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-01-17 14:26:00 → RDU 2027-01-17 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-01-17 14:26:00 → MIA 2027-01-17 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-01-17 19:40:00 → RDU 2027-01-17 22:04:00.

2027-01-03 → 2027-01-17 · Axel-exclusive $605.13

• Copa Airlines CM467: RDU 2027-01-03 15:06:00 → PTY 2027-01-03 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-01-17 08:57:00 → RDU 2027-01-17 13:21:00; nonstop; 264 minutes. Local airport times.

Explore this route

• All dates for this route
• Jan 2, 2027 · Return options
• Jan 4, 2027 · Return options
• Hotels in Panama City with Axel

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• This page: Raleigh/Durham (RDU) to Panama City (PTY) · Jan 3, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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