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Raleigh/Durham → Panama City

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RDU → PTY1 adulteconomy

17 flight options · 4 airlines

Round-trip flights

Fri, Nov 27 – Fri, Dec 4

Copa Airlines
3:06 pmRDU
4h 33m
Nonstop
7:39 pmPTY
Copa Airlines
8:57 amPTY
4h 24m
Nonstop
1:21 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
7:00 amRDU
8h 33m
MIA · 2h 55m
3:33 pmPTY
American Airlines
2:26 pmPTY
7h 38m
MIA · 2h 6m
10:04 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
10:39 amRDU
9h 56m
IAD · 3h 40m
8:35 pmPTY
United Airlines
11:55 pmPTY
9h 20m
EWR · 2h 34m
9:15 am+1RDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
5:07 amRDU
8h 57m
ATL · 3h 15m
2:04 pmPTY
Delta Air Lines
8:00 amPTY
9h 1m
ATL · 3h 18m
5:01 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Copa Airlines
3:06 pmRDU
4h 33m
Nonstop
7:39 pmPTY
Copa Airlines
8:57 amPTY
4h 19m
Nonstop
1:16 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
7:00 amRDU
8h 33m
MIA · 2h 55m
3:33 pmPTY
American Airlines
2:26 pmPTY
7h 38m
MIA · 2h 6m
10:04 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
11:24 amRDU
8h 38m
EWR · 1h 18m
8:02 pmPTY
United Airlines
11:55 pmPTY
9h 20m
EWR · 2h 34m
9:15 am+1RDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
11:24 amRDU
8h 38m
EWR · 1h 18m
8:02 pmPTY
United Airlines
11:55 pmPTY
9h 20m
EWR · 2h 34m
9:15 am+1RDU

Round-trip total · 1 adult · Taxes included

Show 4 more flights

Fri, Nov 20 – Mon, Nov 23

United Airlines
10:39 amRDU
9h 56m
IAD · 3h 40m
8:35 pmPTY
United Airlines
11:55 pmPTY
9h 20m
EWR · 2h 34m
9:15 am+1RDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
5:07 amRDU
8h 57m
ATL · 3h 15m
2:04 pmPTY
Delta Air Lines
8:00 amPTY
9h 1m
ATL · 3h 18m
5:01 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Copa Airlines
3:17 pmRDU
4h 29m
Nonstop
7:46 pmPTY
Copa Airlines
9:11 amPTY
9h 40m
IAD · 3h 37m
6:51 pmRDU

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Copa Airlines
3:17 pmRDU
4h 29m
Nonstop
7:46 pmPTY
Copa Airlines
9:11 amPTY
9h 40m
IAD · 3h 37m
6:51 pmRDU

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Copa Airlines
3:06 pmRDU
4h 33m
Nonstop
7:39 pmPTY

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
7:00 amRDU
8h 33m
MIA · 2h 55m
3:33 pmPTY

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
10:39 amRDU
9h 56m
IAD · 3h 40m
8:35 pmPTY

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
5:07 amRDU
8h 57m
ATL · 3h 15m
2:04 pmPTY

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
11:24 amRDU
8h 38m
EWR · 1h 18m
8:02 pmPTY

One-way total · 1 adult · Taxes included

Make this trip yours

RDU ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Copa Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one wayCopa AirlinesCM467$285.002026-10-29T01:03:01Z
2026-11-27 → 2026-12-04Copa AirlinesCM467 / CM466$561.352026-10-29T01:03:01Z
2026-11-20 · one wayAmerican AirlinesAA1088 + AA2177$255.002026-10-29T01:03:01Z
2026-11-20 · one wayUnited AirlinesUA1535 + CM444$265.002026-10-29T01:03:01Z
2026-11-20 · one wayDelta Air LinesDL1552 + DL1759$275.002026-10-29T01:03:01Z
2026-11-20 → 2026-11-23American AirlinesAA1088 + AA2177 / AA388 + AA1381$506.852026-10-29T01:03:01Z
2026-11-27 → 2026-12-04United AirlinesUA1535 + CM444 / UA1703 + UA1890$528.652026-10-29T01:03:01Z
2026-11-27 → 2026-12-04Delta Air LinesDL1552 + DL1759 / DL1904 + DL2600$539.552026-10-29T01:03:01Z
2026-11-20 → 2026-11-23Copa AirlinesCM467 / CM466$561.352026-10-29T01:03:01Z
2026-11-20 · one wayUnited AirlinesUA1536 + UA1021$265.002026-10-29T01:03:01Z
2026-11-27 → 2026-12-04American AirlinesAA1088 + AA2177 / AA388 + AA1381$506.852026-10-29T01:03:01Z
2026-11-27 → 2026-12-04United AirlinesUA1536 + UA1021 / UA1703 + UA1890$528.652026-10-29T01:03:01Z
2026-11-20 → 2026-11-23United AirlinesUA1536 + UA1021 / UA1703 + UA1890$528.652026-10-29T01:03:01Z
2026-11-20 → 2026-11-23United AirlinesUA1535 + CM444 / UA1703 + UA1890$528.652026-10-29T01:03:01Z
2026-11-20 → 2026-11-23Delta Air LinesDL1552 + DL1759 / DL1904 + DL2600$539.552026-10-29T01:03:01Z
2026-11-20 → 2026-11-23Copa AirlinesCM467 / CM443 + UA2344$549.552026-10-29T01:03:01Z
2026-11-27 → 2026-12-04Copa AirlinesCM467 / CM443 + UA2344$551.352026-10-29T01:03:01Z

2026-11-20 · one way · $285.00

  • Copa Airlines CM467: RDU 2026-11-20 15:06:00 → PTY 2026-11-20 19:39:00; nonstop; 273 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $561.35

  • Copa Airlines CM467: RDU 2026-11-27 15:06:00 → PTY 2026-11-27 19:39:00; nonstop; 273 minutes. Local airport times.
  • Copa Airlines CM466: PTY 2026-12-04 08:57:00 → RDU 2026-12-04 13:21:00; nonstop; 264 minutes. Local airport times.

2026-11-20 · one way · $255.00

  • American Airlines AA1088 / AA2177: RDU 2026-11-20 07:00:00 → PTY 2026-11-20 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
    • AA1088: RDU 2026-11-20 07:00:00 → MIA 2026-11-20 09:22:00; layover at MIA: 175 minutes.
    • AA2177: MIA 2026-11-20 12:17:00 → PTY 2026-11-20 15:33:00.

2026-11-20 · one way · $265.00

  • United Airlines UA1535 / CM444: RDU 2026-11-20 10:39:00 → PTY 2026-11-20 20:35:00; 1 stop(s) via IAD; 596 minutes. Local airport times.
    • UA1535: RDU 2026-11-20 10:39:00 → IAD 2026-11-20 11:50:00; layover at IAD: 220 minutes.
    • CM444: IAD 2026-11-20 15:30:00 → PTY 2026-11-20 20:35:00.

2026-11-20 · one way · $275.00

  • Delta Air Lines DL1552 / DL1759: RDU 2026-11-20 05:07:00 → PTY 2026-11-20 14:04:00; 1 stop(s) via ATL; 537 minutes. Local airport times.
    • DL1552: RDU 2026-11-20 05:07:00 → ATL 2026-11-20 06:39:00; layover at ATL: 195 minutes.
    • DL1759: ATL 2026-11-20 09:54:00 → PTY 2026-11-20 14:04:00.

2026-11-20 → 2026-11-23 · $506.85

  • American Airlines AA1088 / AA2177: RDU 2026-11-20 07:00:00 → PTY 2026-11-20 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
    • AA1088: RDU 2026-11-20 07:00:00 → MIA 2026-11-20 09:22:00; layover at MIA: 175 minutes.
    • AA2177: MIA 2026-11-20 12:17:00 → PTY 2026-11-20 15:33:00.
  • American Airlines AA388 / AA1381: PTY 2026-11-23 14:26:00 → RDU 2026-11-23 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
    • AA388: PTY 2026-11-23 14:26:00 → MIA 2026-11-23 17:34:00; layover at MIA: 126 minutes.
    • AA1381: MIA 2026-11-23 19:40:00 → RDU 2026-11-23 22:04:00.

2026-11-27 → 2026-12-04 · $528.65

  • United Airlines UA1535 / CM444: RDU 2026-11-27 10:39:00 → PTY 2026-11-27 20:35:00; 1 stop(s) via IAD; 596 minutes. Local airport times.
    • UA1535: RDU 2026-11-27 10:39:00 → IAD 2026-11-27 11:50:00; layover at IAD: 220 minutes.
    • CM444: IAD 2026-11-27 15:30:00 → PTY 2026-11-27 20:35:00.
  • United Airlines UA1703 / UA1890: PTY 2026-12-04 23:55:00 → RDU 2026-12-05 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
    • UA1703: PTY 2026-12-04 23:55:00 → EWR 2026-12-05 04:56:00; layover at EWR: 154 minutes.
    • UA1890: EWR 2026-12-05 07:30:00 → RDU 2026-12-05 09:15:00.

2026-11-27 → 2026-12-04 · $539.55

  • Delta Air Lines DL1552 / DL1759: RDU 2026-11-27 05:07:00 → PTY 2026-11-27 14:04:00; 1 stop(s) via ATL; 537 minutes. Local airport times.
    • DL1552: RDU 2026-11-27 05:07:00 → ATL 2026-11-27 06:39:00; layover at ATL: 195 minutes.
    • DL1759: ATL 2026-11-27 09:54:00 → PTY 2026-11-27 14:04:00.
  • Delta Air Lines DL1904 / DL2600: PTY 2026-12-04 08:00:00 → RDU 2026-12-04 17:01:00; 1 stop(s) via ATL; 541 minutes. Local airport times.
    • DL1904: PTY 2026-12-04 08:00:00 → ATL 2026-12-04 12:19:00; layover at ATL: 198 minutes.
    • DL2600: ATL 2026-12-04 15:37:00 → RDU 2026-12-04 17:01:00.

2026-11-20 → 2026-11-23 · $561.35

  • Copa Airlines CM467: RDU 2026-11-20 15:06:00 → PTY 2026-11-20 19:39:00; nonstop; 273 minutes. Local airport times.
  • Copa Airlines CM466: PTY 2026-11-23 08:57:00 → RDU 2026-11-23 13:16:00; nonstop; 259 minutes. Local airport times.

2026-11-20 · one way · $265.00

  • United Airlines UA1536 / UA1021: RDU 2026-11-20 11:24:00 → PTY 2026-11-20 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
    • UA1536: RDU 2026-11-20 11:24:00 → EWR 2026-11-20 13:29:00; layover at EWR: 78 minutes.
    • UA1021: EWR 2026-11-20 14:47:00 → PTY 2026-11-20 20:02:00.

2026-11-27 → 2026-12-04 · $506.85

  • American Airlines AA1088 / AA2177: RDU 2026-11-27 07:00:00 → PTY 2026-11-27 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
    • AA1088: RDU 2026-11-27 07:00:00 → MIA 2026-11-27 09:22:00; layover at MIA: 175 minutes.
    • AA2177: MIA 2026-11-27 12:17:00 → PTY 2026-11-27 15:33:00.
  • American Airlines AA388 / AA1381: PTY 2026-12-04 14:26:00 → RDU 2026-12-04 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
    • AA388: PTY 2026-12-04 14:26:00 → MIA 2026-12-04 17:34:00; layover at MIA: 126 minutes.
    • AA1381: MIA 2026-12-04 19:40:00 → RDU 2026-12-04 22:04:00.

2026-11-27 → 2026-12-04 · $528.65

  • United Airlines UA1536 / UA1021: RDU 2026-11-27 11:24:00 → PTY 2026-11-27 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
    • UA1536: RDU 2026-11-27 11:24:00 → EWR 2026-11-27 13:29:00; layover at EWR: 78 minutes.
    • UA1021: EWR 2026-11-27 14:47:00 → PTY 2026-11-27 20:02:00.
  • United Airlines UA1703 / UA1890: PTY 2026-12-04 23:55:00 → RDU 2026-12-05 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
    • UA1703: PTY 2026-12-04 23:55:00 → EWR 2026-12-05 04:56:00; layover at EWR: 154 minutes.
    • UA1890: EWR 2026-12-05 07:30:00 → RDU 2026-12-05 09:15:00.

2026-11-20 → 2026-11-23 · $528.65

  • United Airlines UA1536 / UA1021: RDU 2026-11-20 11:24:00 → PTY 2026-11-20 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
    • UA1536: RDU 2026-11-20 11:24:00 → EWR 2026-11-20 13:29:00; layover at EWR: 78 minutes.
    • UA1021: EWR 2026-11-20 14:47:00 → PTY 2026-11-20 20:02:00.
  • United Airlines UA1703 / UA1890: PTY 2026-11-23 23:55:00 → RDU 2026-11-24 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
    • UA1703: PTY 2026-11-23 23:55:00 → EWR 2026-11-24 04:56:00; layover at EWR: 154 minutes.
    • UA1890: EWR 2026-11-24 07:30:00 → RDU 2026-11-24 09:15:00.

2026-11-20 → 2026-11-23 · $528.65

  • United Airlines UA1535 / CM444: RDU 2026-11-20 10:39:00 → PTY 2026-11-20 20:35:00; 1 stop(s) via IAD; 596 minutes. Local airport times.
    • UA1535: RDU 2026-11-20 10:39:00 → IAD 2026-11-20 11:50:00; layover at IAD: 220 minutes.
    • CM444: IAD 2026-11-20 15:30:00 → PTY 2026-11-20 20:35:00.
  • United Airlines UA1703 / UA1890: PTY 2026-11-23 23:55:00 → RDU 2026-11-24 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
    • UA1703: PTY 2026-11-23 23:55:00 → EWR 2026-11-24 04:56:00; layover at EWR: 154 minutes.
    • UA1890: EWR 2026-11-24 07:30:00 → RDU 2026-11-24 09:15:00.

2026-11-20 → 2026-11-23 · $539.55

  • Delta Air Lines DL1552 / DL1759: RDU 2026-11-20 05:07:00 → PTY 2026-11-20 14:04:00; 1 stop(s) via ATL; 537 minutes. Local airport times.
    • DL1552: RDU 2026-11-20 05:07:00 → ATL 2026-11-20 06:39:00; layover at ATL: 195 minutes.
    • DL1759: ATL 2026-11-20 09:54:00 → PTY 2026-11-20 14:04:00.
  • Delta Air Lines DL1904 / DL2600: PTY 2026-11-23 08:00:00 → RDU 2026-11-23 17:01:00; 1 stop(s) via ATL; 541 minutes. Local airport times.
    • DL1904: PTY 2026-11-23 08:00:00 → ATL 2026-11-23 12:19:00; layover at ATL: 198 minutes.
    • DL2600: ATL 2026-11-23 15:37:00 → RDU 2026-11-23 17:01:00.

2026-11-20 → 2026-11-23 · $549.55

  • Copa Airlines CM467: RDU 2026-11-20 15:17:00 → PTY 2026-11-20 19:46:00; nonstop; 269 minutes. Local airport times.
  • Copa Airlines CM443 / UA2344: PTY 2026-11-23 09:11:00 → RDU 2026-11-23 18:51:00; 1 stop(s) via IAD; 580 minutes. Local airport times.
    • CM443: PTY 2026-11-23 09:11:00 → IAD 2026-11-23 13:58:00; layover at IAD: 217 minutes.
    • UA2344: IAD 2026-11-23 17:35:00 → RDU 2026-11-23 18:51:00.

2026-11-27 → 2026-12-04 · $551.35

  • Copa Airlines CM467: RDU 2026-11-27 15:17:00 → PTY 2026-11-27 19:46:00; nonstop; 269 minutes. Local airport times.
  • Copa Airlines CM443 / UA2344: PTY 2026-12-04 09:11:00 → RDU 2026-12-04 18:51:00; 1 stop(s) via IAD; 580 minutes. Local airport times.
    • CM443: PTY 2026-12-04 09:11:00 → IAD 2026-12-04 13:58:00; layover at IAD: 217 minutes.
    • UA2344: IAD 2026-12-04 17:35:00 → RDU 2026-12-04 18:51:00.

More dates for this route