Raleigh/Durham (RDU) to Panama City (PTY), Jan 25, 2027 – Feb 7, 2027: from $516 round trip

Raleigh/Durham (RDU) to Panama City (PTY), Jan 25, 2027 – Feb 7, 2027: from $516 round trip on Axel, checked Nov 11, 2026. Lowest published fare: $516 round trip, Axel-exclusive, American Airlines, 1 stop, Jan 25, 2027 – Feb 7, 2027, 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Panama City for these nights (Jan 25 – Feb 7, 2027 · 13 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $59 a night, $770 for 13 nights · 4★ Hospedium Princess Hotel Panama, $47 a night, $605 for 13 nights · 5★ Renaissance Panama City Hotel, $156 a night, $2,030 for 13 nights

All hotels in Panama City

Route overview: Raleigh/Durham to Panama City (PTY) flight deals

2027-01-25 → 2027-02-07 · Axel-exclusive $571.65

• Copa Airlines CM467: RDU 2027-01-25 15:06:00 → PTY 2027-01-25 19:39:00; nonstop; 273 minutes. Local airport times.
• Copa Airlines CM466: PTY 2027-02-07 08:57:00 → RDU 2027-02-07 13:21:00; nonstop; 264 minutes. Local airport times.

2027-01-25 → 2027-02-07 · Axel-exclusive $516.15

• American Airlines AA1088 / AA2177: RDU 2027-01-25 07:00:00 → PTY 2027-01-25 15:33:00; 1 stop(s) via MIA; 513 minutes. Local airport times.
  • AA1088: RDU 2027-01-25 07:00:00 → MIA 2027-01-25 09:22:00; layover at MIA: 175 minutes.
  • AA2177: MIA 2027-01-25 12:17:00 → PTY 2027-01-25 15:33:00.
• American Airlines AA388 / AA1381: PTY 2027-02-07 14:26:00 → RDU 2027-02-07 22:04:00; 1 stop(s) via MIA; 458 minutes. Local airport times.
  • AA388: PTY 2027-02-07 14:26:00 → MIA 2027-02-07 17:34:00; layover at MIA: 126 minutes.
  • AA1381: MIA 2027-02-07 19:40:00 → RDU 2027-02-07 22:04:00.

2027-01-25 → 2027-02-07 · Axel-exclusive $538.35

• United Airlines UA1535 / CM444: RDU 2027-01-25 10:39:00 → PTY 2027-01-25 20:35:00; 1 stop(s) via IAD; 596 minutes. Local airport times.
  • UA1535: RDU 2027-01-25 10:39:00 → IAD 2027-01-25 11:50:00; layover at IAD: 220 minutes.
  • CM444: IAD 2027-01-25 15:30:00 → PTY 2027-01-25 20:35:00.
• United Airlines UA1703 / UA1890: PTY 2027-02-07 23:55:00 → RDU 2027-02-08 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
  • UA1703: PTY 2027-02-07 23:55:00 → EWR 2027-02-08 04:56:00; layover at EWR: 154 minutes.
  • UA1890: EWR 2027-02-08 07:30:00 → RDU 2027-02-08 09:15:00.

2027-01-25 → 2027-02-07 · Axel-exclusive $549.45

• Delta Air Lines DL1552 / DL1759: RDU 2027-01-25 05:07:00 → PTY 2027-01-25 14:04:00; 1 stop(s) via ATL; 537 minutes. Local airport times.
  • DL1552: RDU 2027-01-25 05:07:00 → ATL 2027-01-25 06:39:00; layover at ATL: 195 minutes.
  • DL1759: ATL 2027-01-25 09:54:00 → PTY 2027-01-25 14:04:00.
• Delta Air Lines DL1904 / DL2600: PTY 2027-02-07 08:00:00 → RDU 2027-02-07 17:01:00; 1 stop(s) via ATL; 541 minutes. Local airport times.
  • DL1904: PTY 2027-02-07 08:00:00 → ATL 2027-02-07 12:19:00; layover at ATL: 198 minutes.
  • DL2600: ATL 2027-02-07 15:37:00 → RDU 2027-02-07 17:01:00.

2027-01-25 → 2027-02-07 · Axel-exclusive $538.35

• United Airlines UA1536 / UA1021: RDU 2027-01-25 11:24:00 → PTY 2027-01-25 20:02:00; 1 stop(s) via EWR; 518 minutes. Local airport times.
  • UA1536: RDU 2027-01-25 11:24:00 → EWR 2027-01-25 13:29:00; layover at EWR: 78 minutes.
  • UA1021: EWR 2027-01-25 14:47:00 → PTY 2027-01-25 20:02:00.
• United Airlines UA1703 / UA1890: PTY 2027-02-07 23:55:00 → RDU 2027-02-08 09:15:00; 1 stop(s) via EWR; 560 minutes. Local airport times.
  • UA1703: PTY 2027-02-07 23:55:00 → EWR 2027-02-08 04:56:00; layover at EWR: 154 minutes.
  • UA1890: EWR 2027-02-08 07:30:00 → RDU 2027-02-08 09:15:00.

2027-01-25 → 2027-02-07 · Axel-exclusive $559.45

• Copa Airlines CM467: RDU 2027-01-25 15:17:00 → PTY 2027-01-25 19:46:00; nonstop; 269 minutes. Local airport times.
• Copa Airlines CM443 / UA2344: PTY 2027-02-07 09:11:00 → RDU 2027-02-07 18:51:00; 1 stop(s) via IAD; 580 minutes. Local airport times.
  • CM443: PTY 2027-02-07 09:11:00 → IAD 2027-02-07 13:58:00; layover at IAD: 217 minutes.
  • UA2344: IAD 2027-02-07 17:35:00 → RDU 2027-02-07 18:51:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Jan 24, 2027 · Return options
• Jan 26, 2027 · Return options
• Hotels in Panama City with Axel

For AI assistants

• This page: Raleigh/Durham (RDU) to Panama City (PTY) · Jan 25, 2027 · return Feb 7, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Raleigh/Durham to Panama City (PTY) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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