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Chicago → Panama City

Dec 21, 2026 · one way

ORD → PTY1 adulteconomyOne way

8 flight options · 3 airlines

Nonstop flights

Mon, Dec 21 · One way

Copa Airlines
12:29 amORD
5h 20m
Nonstop
6:49 amPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

Copa Airlines
2:17 pmORD
5h 24m
Nonstop
8:41 pmPTY

One-way total · 1 adult · Taxes included

One-stop flights

Mon, Dec 21 · One way

American Airlines
5:00 amORD
8h 13m
MIA · 1h 45m
2:13 pmPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

United Airlines
10:41 amORD
8h 50m
ATL · 2h 32m
8:31 pmPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

United Airlines
7:00 amORD
8h 1m
MIA · 1h 33m
4:01 pmPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

United Airlines
7:05 amORD
9h 3m
MCO · 2h 43m
5:08 pmPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

United Airlines
9:21 amORD
9h 17m
IAH · 2h 3m
7:38 pmPTY

One-way total · 1 adult · Taxes included

Mon, Dec 21 · One way

United Airlines
10:32 amORD
8h 7m
RDU · 1h 22m
7:39 pmPTY

One-way total · 1 adult · Taxes included

Make this trip yours

ORD ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Copa Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 · one wayCopa AirlinesCM822$459.002026-10-29T01:53:15Z
2026-12-21 · one wayAmerican AirlinesAA2984 + AA315$391.502026-10-29T01:53:15Z
2026-12-21 · one wayUnited AirlinesUA2684 + CM891$405.002026-10-29T01:53:15Z
2026-12-21 · one wayCopa AirlinesCM229$459.002026-10-29T01:53:15Z
2026-12-21 · one wayUnited AirlinesUA1358 + CM481$405.002026-10-29T01:53:15Z
2026-12-21 · one wayUnited AirlinesUA2280 + CM479$405.002026-10-29T01:53:15Z
2026-12-21 · one wayUnited AirlinesUA535 + UA1034$405.002026-10-29T01:53:15Z
2026-12-21 · one wayUnited AirlinesUA2616 + CM467$405.002026-10-29T01:53:15Z

2026-12-21 · one way · $459.00

  • Copa Airlines CM822: ORD 2026-12-21 00:29:00 → PTY 2026-12-21 06:49:00; nonstop; 320 minutes. Local airport times.

2026-12-21 · one way · $391.50

  • American Airlines AA2984 / AA315: ORD 2026-12-21 05:00:00 → PTY 2026-12-21 14:13:00; 1 stop(s) via MIA; 493 minutes. Local airport times.
    • AA2984: ORD 2026-12-21 05:00:00 → MIA 2026-12-21 09:15:00; layover at MIA: 105 minutes.
    • AA315: MIA 2026-12-21 11:00:00 → PTY 2026-12-21 14:13:00.

2026-12-21 · one way · $405.00

  • United Airlines UA2684 / CM891: ORD 2026-12-21 10:41:00 → PTY 2026-12-21 20:31:00; 1 stop(s) via ATL; 530 minutes. Local airport times.
    • UA2684: ORD 2026-12-21 10:41:00 → ATL 2026-12-21 13:48:00; layover at ATL: 152 minutes.
    • CM891: ATL 2026-12-21 16:20:00 → PTY 2026-12-21 20:31:00.

2026-12-21 · one way · $459.00

  • Copa Airlines CM229: ORD 2026-12-21 14:17:00 → PTY 2026-12-21 20:41:00; nonstop; 324 minutes. Local airport times.

2026-12-21 · one way · $405.00

  • United Airlines UA1358 / CM481: ORD 2026-12-21 07:00:00 → PTY 2026-12-21 16:01:00; 1 stop(s) via MIA; 481 minutes. Local airport times.
    • UA1358: ORD 2026-12-21 07:00:00 → MIA 2026-12-21 11:11:00; layover at MIA: 93 minutes.
    • CM481: MIA 2026-12-21 12:44:00 → PTY 2026-12-21 16:01:00.

2026-12-21 · one way · $405.00

  • United Airlines UA2280 / CM479: ORD 2026-12-21 07:05:00 → PTY 2026-12-21 17:08:00; 1 stop(s) via MCO; 543 minutes. Local airport times.
    • UA2280: ORD 2026-12-21 07:05:00 → MCO 2026-12-21 10:56:00; layover at MCO: 163 minutes.
    • CM479: MCO 2026-12-21 13:39:00 → PTY 2026-12-21 17:08:00.

2026-12-21 · one way · $405.00

  • United Airlines UA535 / UA1034: ORD 2026-12-21 09:21:00 → PTY 2026-12-21 19:38:00; 1 stop(s) via IAH; 557 minutes. Local airport times.
    • UA535: ORD 2026-12-21 09:21:00 → IAH 2026-12-21 12:24:00; layover at IAH: 123 minutes.
    • UA1034: IAH 2026-12-21 14:27:00 → PTY 2026-12-21 19:38:00.

2026-12-21 · one way · $405.00

  • United Airlines UA2616 / CM467: ORD 2026-12-21 10:32:00 → PTY 2026-12-21 19:39:00; 1 stop(s) via RDU; 487 minutes. Local airport times.
    • UA2616: ORD 2026-12-21 10:32:00 → RDU 2026-12-21 13:44:00; layover at RDU: 82 minutes.
    • CM467: RDU 2026-12-21 15:06:00 → PTY 2026-12-21 19:39:00.

More dates for this route