Travel with Axel,
get the best price.

Jacksonville → Saint Louis

Dec 21, 2026 · return Dec 26, 2026

JAX → STL1 adulteconomyRound trip

8 flight options · 4 airlines

Nonstop flights

Mon, Dec 21 – Sat, Dec 26

Southwest Airlines
7:35 pmJAX
2h 15m
Nonstop
8:50 pmSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

Southwest Airlines
5:45 amJAX
2h 20m
Nonstop
7:05 amSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

One-stop flights

Mon, Dec 21 – Sat, Dec 26

American Airlines
6:20 amJAX
4h 59m
CLT · 1h 25m
10:19 amSTL
American Airlines
5:02 amSTL
5h 38m
ORD · 1h 35m
11:40 amJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

United Airlines
7:30 amJAX
5h 52m
ORD · 1h 33m
12:22 pmSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

Delta Air Lines
2:27 pmJAX
4h 34m
ATL · 1h 38m
6:01 pmSTL
Delta Air Lines
10:06 amSTL
5h 36m
ATL · 2h 59m
4:42 pmJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

Southwest Airlines
7:05 pmJAX
5h 50m
BNA · 3h
11:55 pmSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

Southwest Airlines
5:40 pmJAX
5h 35m
BWI · 1h 20m
10:15 pmSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

Mon, Dec 21 – Sat, Dec 26

United Airlines
5:22 pmJAX
6h 8m
IAH · 1h 13m
10:30 pmSTL
Southwest Airlines
10:05 amSTL
1h 55m
Nonstop
1:00 pmJAX

Round-trip total · 1 adult · Taxes included

Make this trip yours

JAX ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

All dates for this routeNov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2026-12-26Southwest AirlinesWN4720 / WN4697$435.502026-10-29T01:17:31Z
2026-12-21 → 2026-12-26American AirlinesAA1576 + AA2486 / AA2317 + AA4151$442.002026-10-29T01:17:31Z
2026-12-21 → 2026-12-26United Airlines / Southwest AirlinesUA2414 + UA1857 / WN4697$445.252026-10-29T01:17:31Z
2026-12-21 → 2026-12-26Delta Air LinesDL3024 + DL1393 / DL1571 + DL2720$468.002026-10-29T01:17:31Z
2026-12-21 → 2026-12-26Southwest AirlinesWN2265 / WN4697$435.502026-10-29T01:17:31Z
2026-12-21 → 2026-12-26Southwest AirlinesWN2760 + WN2043 / WN4697$425.752026-10-29T01:17:31Z
2026-12-21 → 2026-12-26Southwest AirlinesWN1329 + WN1390 / WN4697$425.752026-10-29T01:17:31Z
2026-12-21 → 2026-12-26United Airlines / Southwest AirlinesUA6157 + UA1030 / WN4697$445.252026-10-29T01:17:31Z

2026-12-21 → 2026-12-26 · $435.50

  • Southwest Airlines WN4720: JAX 2026-12-21 19:35:00 → STL 2026-12-21 20:50:00; nonstop; 135 minutes. Local airport times.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-21 → 2026-12-26 · $442.00

  • American Airlines AA1576 / AA2486: JAX 2026-12-21 06:20:00 → STL 2026-12-21 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
    • AA1576: JAX 2026-12-21 06:20:00 → CLT 2026-12-21 07:50:00; layover at CLT: 85 minutes.
    • AA2486: CLT 2026-12-21 09:15:00 → STL 2026-12-21 10:19:00.
  • American Airlines AA2317 / AA4151: STL 2026-12-26 05:02:00 → JAX 2026-12-26 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
    • AA2317: STL 2026-12-26 05:02:00 → ORD 2026-12-26 06:30:00; layover at ORD: 95 minutes.
    • AA4151: ORD 2026-12-26 08:05:00 → JAX 2026-12-26 11:40:00.

2026-12-21 → 2026-12-26 · $445.25

  • United Airlines UA2414 / UA1857: JAX 2026-12-21 07:30:00 → STL 2026-12-21 12:22:00; 1 stop(s) via ORD; 352 minutes. Local airport times.
    • UA2414: JAX 2026-12-21 07:30:00 → ORD 2026-12-21 09:19:00; layover at ORD: 93 minutes.
    • UA1857: ORD 2026-12-21 10:52:00 → STL 2026-12-21 12:22:00.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-21 → 2026-12-26 · $468.00

  • Delta Air Lines DL3024 / DL1393: JAX 2026-12-21 14:27:00 → STL 2026-12-21 18:01:00; 1 stop(s) via ATL; 274 minutes. Local airport times.
    • DL3024: JAX 2026-12-21 14:27:00 → ATL 2026-12-21 15:42:00; layover at ATL: 98 minutes.
    • DL1393: ATL 2026-12-21 17:20:00 → STL 2026-12-21 18:01:00.
  • Delta Air Lines DL1571 / DL2720: STL 2026-12-26 10:06:00 → JAX 2026-12-26 16:42:00; 1 stop(s) via ATL; 336 minutes. Local airport times.
    • DL1571: STL 2026-12-26 10:06:00 → ATL 2026-12-26 12:36:00; layover at ATL: 179 minutes.
    • DL2720: ATL 2026-12-26 15:35:00 → JAX 2026-12-26 16:42:00.

2026-12-21 → 2026-12-26 · $435.50

  • Southwest Airlines WN2265: JAX 2026-12-21 05:45:00 → STL 2026-12-21 07:05:00; nonstop; 140 minutes. Local airport times.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-21 → 2026-12-26 · $425.75

  • Southwest Airlines WN2760 / WN2043: JAX 2026-12-21 19:05:00 → STL 2026-12-21 23:55:00; 1 stop(s) via BNA; 350 minutes. Local airport times.
    • WN2760: JAX 2026-12-21 19:05:00 → BNA 2026-12-21 19:40:00; layover at BNA: 180 minutes.
    • WN2043: BNA 2026-12-21 22:40:00 → STL 2026-12-21 23:55:00.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-21 → 2026-12-26 · $425.75

  • Southwest Airlines WN1329 / WN1390: JAX 2026-12-21 17:40:00 → STL 2026-12-21 22:15:00; 1 stop(s) via BWI; 335 minutes. Local airport times.
    • WN1329: JAX 2026-12-21 17:40:00 → BWI 2026-12-21 19:30:00; layover at BWI: 80 minutes.
    • WN1390: BWI 2026-12-21 20:50:00 → STL 2026-12-21 22:15:00.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-21 → 2026-12-26 · $445.25

  • United Airlines UA6157 / UA1030: JAX 2026-12-21 17:22:00 → STL 2026-12-21 22:30:00; 1 stop(s) via IAH; 368 minutes. Local airport times.
    • UA6157: JAX 2026-12-21 17:22:00 → IAH 2026-12-21 19:10:00; layover at IAH: 73 minutes.
    • UA1030: IAH 2026-12-21 20:23:00 → STL 2026-12-21 22:30:00.
  • Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

More dates for this route