Travel with Axel,
get the best price.

Route overview: Detroit to Knoxville (TYS) flight deals

Detroit → Knoxville

Dec 22, 2026 · return Dec 28, 2026

DTW → TYS1 adulteconomyRound trip

8 flight options · 4 airlines

Nonstop flights

Tue, Dec 22 – Mon, Dec 28

Delta Air Lines
7:58 pmDTW
1h 35m
Nonstop
9:33 pmTYS
Delta Air Lines
5:10 pmTYS
1h 47m
Nonstop
6:57 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

Delta Air Lines
4:10 pmDTW
1h 39m
Nonstop
5:49 pmTYS
Delta Air Lines
5:10 pmTYS
1h 47m
Nonstop
6:57 pmDTW

Round-trip total · 1 adult · Taxes included

One-stop flights

Tue, Dec 22 – Mon, Dec 28

Southwest Airlines
3:55 pmDTW
4h 55m
BWI · 1h 40m
8:50 pmTYS
Southwest Airlines
5:15 pmTYS
4h 10m
BNA · 1h 20m
9:25 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

American Airlines
1:40 pmDTW
5h 6m
ORD · 1h 43m
6:46 pmTYS
American Airlines
8:50 amTYS
6h 53m
CLT · 3h 38m
3:43 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

United Airlines
7:45 pmDTW
4h 30m
IAD · 1h 2m
12:15 am+1TYS
United Airlines
2:07 pmTYS
5h 2m
IAD · 1h 35m
7:09 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

Southwest Airlines
6:00 amDTW
6h 20m
BNA · 3h 25m
12:20 pmTYS
Southwest Airlines
5:15 pmTYS
4h 10m
BNA · 1h 20m
9:25 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

American Airlines
4:50 pmDTW
5h 7m
CLT · 1h 55m
9:57 pmTYS
American Airlines
8:50 amTYS
6h 53m
CLT · 3h 38m
3:43 pmDTW

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Mon, Dec 28

Delta Air Lines
3:59 pmDTW
5h 57m
ATL · 2h 49m
9:56 pmTYS
Delta Air Lines
5:10 pmTYS
1h 47m
Nonstop
6:57 pmDTW

Round-trip total · 1 adult · Taxes included

Make this trip yours

DTW ⇄ TYS

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Delta Air Lines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

Explore this route

All dates for this routeDec 21, 2026 → Dec 27, 2026Dec 23, 2026 → Dec 29, 2026
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Route overview: Detroit to Knoxville (TYS) flight deals

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-22 → 2026-12-28Delta Air LinesDL5138 / DL4697$431.262026-10-29T01:11:31Z
2026-12-22 → 2026-12-28Southwest AirlinesWN2069 + WN3687 / WN463 + WN1991$356.262026-10-29T01:11:31Z
2026-12-22 → 2026-12-28American AirlinesAA3364 + AA3661 / AA5118 + AA2376$368.762026-10-29T01:11:31Z
2026-12-22 → 2026-12-28United AirlinesUA6362 + UA4304 / UA4848 + UA6246$393.762026-10-29T01:11:31Z
2026-12-22 → 2026-12-28Delta Air LinesDL4989 / DL4697$431.262026-10-29T01:11:31Z
2026-12-22 → 2026-12-28Southwest AirlinesWN4679 + WN1875 / WN463 + WN1991$356.262026-10-29T01:11:31Z
2026-12-22 → 2026-12-28American AirlinesAA3311 + AA5292 / AA5118 + AA2376$368.762026-10-29T01:11:31Z
2026-12-22 → 2026-12-28Delta Air LinesDL1467 + DL5272 / DL4697$406.262026-10-29T01:11:31Z

2026-12-22 → 2026-12-28 · $431.26

  • Delta Air Lines DL5138: DTW 2026-12-22 19:58:00 → TYS 2026-12-22 21:33:00; nonstop; 95 minutes. Local airport times.
  • Delta Air Lines DL4697: TYS 2026-12-28 17:10:00 → DTW 2026-12-28 18:57:00; nonstop; 107 minutes. Local airport times.

2026-12-22 → 2026-12-28 · $356.26

  • Southwest Airlines WN2069 / WN3687: DTW 2026-12-22 15:55:00 → TYS 2026-12-22 20:50:00; 1 stop(s) via BWI; 295 minutes. Local airport times.
    • WN2069: DTW 2026-12-22 15:55:00 → BWI 2026-12-22 17:25:00; layover at BWI: 100 minutes.
    • WN3687: BWI 2026-12-22 19:05:00 → TYS 2026-12-22 20:50:00.
  • Southwest Airlines WN463 / WN1991: TYS 2026-12-28 17:15:00 → DTW 2026-12-28 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
    • WN463: TYS 2026-12-28 17:15:00 → BNA 2026-12-28 17:15:00; layover at BNA: 80 minutes.
    • WN1991: BNA 2026-12-28 18:35:00 → DTW 2026-12-28 21:25:00.

2026-12-22 → 2026-12-28 · $368.76

  • American Airlines AA3364 / AA3661: DTW 2026-12-22 13:40:00 → TYS 2026-12-22 18:46:00; 1 stop(s) via ORD; 306 minutes. Local airport times.
    • AA3364: DTW 2026-12-22 13:40:00 → ORD 2026-12-22 14:17:00; layover at ORD: 103 minutes.
    • AA3661: ORD 2026-12-22 16:00:00 → TYS 2026-12-22 18:46:00.
  • American Airlines AA5118 / AA2376: TYS 2026-12-28 08:50:00 → DTW 2026-12-28 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
    • AA5118: TYS 2026-12-28 08:50:00 → CLT 2026-12-28 10:17:00; layover at CLT: 218 minutes.
    • AA2376: CLT 2026-12-28 13:55:00 → DTW 2026-12-28 15:43:00.

2026-12-22 → 2026-12-28 · $393.76

  • United Airlines UA6362 / UA4304: DTW 2026-12-22 19:45:00 → TYS 2026-12-23 00:15:00; 1 stop(s) via IAD; 270 minutes. Local airport times.
    • UA6362: DTW 2026-12-22 19:45:00 → IAD 2026-12-22 21:19:00; layover at IAD: 62 minutes.
    • UA4304: IAD 2026-12-22 22:21:00 → TYS 2026-12-23 00:15:00.
  • United Airlines UA4848 / UA6246: TYS 2026-12-28 14:07:00 → DTW 2026-12-28 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
    • UA4848: TYS 2026-12-28 14:07:00 → IAD 2026-12-28 15:50:00; layover at IAD: 95 minutes.
    • UA6246: IAD 2026-12-28 17:25:00 → DTW 2026-12-28 19:09:00.

2026-12-22 → 2026-12-28 · $431.26

  • Delta Air Lines DL4989: DTW 2026-12-22 16:10:00 → TYS 2026-12-22 17:49:00; nonstop; 99 minutes. Local airport times.
  • Delta Air Lines DL4697: TYS 2026-12-28 17:10:00 → DTW 2026-12-28 18:57:00; nonstop; 107 minutes. Local airport times.

2026-12-22 → 2026-12-28 · $356.26

  • Southwest Airlines WN4679 / WN1875: DTW 2026-12-22 06:00:00 → TYS 2026-12-22 12:20:00; 1 stop(s) via BNA; 380 minutes. Local airport times.
    • WN4679: DTW 2026-12-22 06:00:00 → BNA 2026-12-22 06:55:00; layover at BNA: 205 minutes.
    • WN1875: BNA 2026-12-22 10:20:00 → TYS 2026-12-22 12:20:00.
  • Southwest Airlines WN463 / WN1991: TYS 2026-12-28 17:15:00 → DTW 2026-12-28 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
    • WN463: TYS 2026-12-28 17:15:00 → BNA 2026-12-28 17:15:00; layover at BNA: 80 minutes.
    • WN1991: BNA 2026-12-28 18:35:00 → DTW 2026-12-28 21:25:00.

2026-12-22 → 2026-12-28 · $368.76

  • American Airlines AA3311 / AA5292: DTW 2026-12-22 16:50:00 → TYS 2026-12-22 21:57:00; 1 stop(s) via CLT; 307 minutes. Local airport times.
    • AA3311: DTW 2026-12-22 16:50:00 → CLT 2026-12-22 18:45:00; layover at CLT: 115 minutes.
    • AA5292: CLT 2026-12-22 20:40:00 → TYS 2026-12-22 21:57:00.
  • American Airlines AA5118 / AA2376: TYS 2026-12-28 08:50:00 → DTW 2026-12-28 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
    • AA5118: TYS 2026-12-28 08:50:00 → CLT 2026-12-28 10:17:00; layover at CLT: 218 minutes.
    • AA2376: CLT 2026-12-28 13:55:00 → DTW 2026-12-28 15:43:00.

2026-12-22 → 2026-12-28 · $406.26

  • Delta Air Lines DL1467 / DL5272: DTW 2026-12-22 15:59:00 → TYS 2026-12-22 21:56:00; 1 stop(s) via ATL; 357 minutes. Local airport times.
    • DL1467: DTW 2026-12-22 15:59:00 → ATL 2026-12-22 18:03:00; layover at ATL: 169 minutes.
    • DL5272: ATL 2026-12-22 20:52:00 → TYS 2026-12-22 21:56:00.
  • Delta Air Lines DL4697: TYS 2026-12-28 17:10:00 → DTW 2026-12-28 18:57:00; nonstop; 107 minutes. Local airport times.

Explore this route