Detroit (DTW) to Saint Louis (STL) · Nov 17, 2026 · return Nov 23, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Detroit to Saint Louis (STL) flight deals

2026-11-17 → 2026-11-23 · Axel-exclusive $275.00

• Southwest Airlines WN1880: DTW 2026-11-17 06:55:00 → STL 2026-11-17 07:45:00; nonstop; 110 minutes. Local airport times.
• Southwest Airlines WN4960: STL 2026-11-23 19:55:00 → DTW 2026-11-23 22:25:00; nonstop; 90 minutes. Local airport times.

2026-11-17 → 2026-11-23 · Axel-exclusive $345.00

• Delta Air Lines DL2822: DTW 2026-11-17 16:30:00 → STL 2026-11-17 17:14:00; nonstop; 104 minutes. Local airport times.
• Delta Air Lines DL1626: STL 2026-11-23 06:40:00 → DTW 2026-11-23 09:13:00; nonstop; 93 minutes. Local airport times.

2026-11-17 → 2026-11-23 · Axel-exclusive $295.00

• American Airlines AA3584 / AA1713: DTW 2026-11-17 10:15:00 → STL 2026-11-17 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
  • AA3584: DTW 2026-11-17 10:15:00 → ORD 2026-11-17 10:55:00; layover at ORD: 214 minutes.
  • AA1713: ORD 2026-11-17 14:29:00 → STL 2026-11-17 15:51:00.
• American Airlines AA6306 / AA3520: STL 2026-11-23 17:19:00 → DTW 2026-11-23 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
  • AA6306: STL 2026-11-23 17:19:00 → ORD 2026-11-23 18:59:00; layover at ORD: 136 minutes.
  • AA3520: ORD 2026-11-23 21:15:00 → DTW 2026-11-23 23:53:00.

2026-11-17 → 2026-11-23 · Axel-exclusive $305.00

• United Airlines UA5381 / UA4412: DTW 2026-11-17 14:00:00 → STL 2026-11-17 19:28:00; 1 stop(s) via ORD; 388 minutes. Local airport times.
  • UA5381: DTW 2026-11-17 14:00:00 → ORD 2026-11-17 14:39:00; layover at ORD: 191 minutes.
  • UA4412: ORD 2026-11-17 17:50:00 → STL 2026-11-17 19:28:00.
• United Airlines UA4439 / UA5756: STL 2026-11-23 05:25:00 → DTW 2026-11-23 13:28:00; 1 stop(s) via ORD; 423 minutes. Local airport times.
  • UA4439: STL 2026-11-23 05:25:00 → ORD 2026-11-23 06:58:00; layover at ORD: 229 minutes.
  • UA5756: ORD 2026-11-23 10:47:00 → DTW 2026-11-23 13:28:00.

2026-11-17 → 2026-11-23 · Axel-exclusive $345.00

• Delta Air Lines DL2868: DTW 2026-11-17 08:40:00 → STL 2026-11-17 09:25:00; nonstop; 105 minutes. Local airport times.
• Delta Air Lines DL1626: STL 2026-11-23 06:40:00 → DTW 2026-11-23 09:13:00; nonstop; 93 minutes. Local airport times.

2026-11-17 → 2026-11-23 · Axel-exclusive $280.00

• Southwest Airlines WN1880: DTW 2026-11-17 06:40:00 → STL 2026-11-17 07:35:00; nonstop; 115 minutes. Local airport times.
• Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
  • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

2026-11-17 → 2026-11-23 · Axel-exclusive $285.00

• Southwest Airlines WN1877 / WN2737: DTW 2026-11-17 08:50:00 → STL 2026-11-17 12:40:00; 1 stop(s) via MDW; 290 minutes. Local airport times.
  • WN1877: DTW 2026-11-17 08:50:00 → MDW 2026-11-17 09:10:00; layover at MDW: 140 minutes.
  • WN2737: MDW 2026-11-17 11:30:00 → STL 2026-11-17 12:40:00.
• Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
  • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

2026-11-17 → 2026-11-23 · Axel-exclusive $285.00

• Southwest Airlines WN1754 / WN2043: DTW 2026-11-17 18:50:00 → STL 2026-11-17 23:55:00; 1 stop(s) via BNA; 365 minutes. Local airport times.
  • WN1754: DTW 2026-11-17 18:50:00 → BNA 2026-11-17 19:40:00; layover at BNA: 180 minutes.
  • WN2043: BNA 2026-11-17 22:40:00 → STL 2026-11-17 23:55:00.
• Southwest Airlines WN665 / WN2971: STL 2026-11-23 10:35:00 → DTW 2026-11-23 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 220 minutes.
  • WN2971: BNA 2026-11-23 15:20:00 → DTW 2026-11-23 18:00:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 16, 2026 · Return options
• Nov 18, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

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