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Route overview: Detroit to Saint Louis (STL) flight deals

Detroit → Saint Louis

Dec 23, 2026 · choose your return date

DTW → STL1 adulteconomyOne way and round trips

30 flight options · 3 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Dec 23, 2026 · One waySouthwest AirlinesNonstop$181.25 Dec 23, 2026 · One wayAmerican AirlinesUp to 1 stop each way$193.75 Dec 23, 2026 – Dec 24, 2026 · 1 nightSouthwest AirlinesNonstop$343.76 Dec 23, 2026 – Dec 24, 2026 · 1 nightAmerican AirlinesUp to 1 stop each way$368.76 Dec 23, 2026 – Dec 25, 2026 · 2 nightsSouthwest AirlinesNonstop$343.76 Dec 23, 2026 – Dec 25, 2026 · 2 nightsAmerican AirlinesUp to 1 stop each way$368.76 Dec 23, 2026 – Dec 26, 2026 · 3 nightsSouthwest AirlinesNonstop$343.76 Dec 23, 2026 – Dec 26, 2026 · 3 nightsAmerican AirlinesUp to 1 stop each way$368.76 Dec 23, 2026 – Dec 27, 2026 · 4 nightsSouthwest AirlinesNonstop$343.76 Dec 23, 2026 – Dec 27, 2026 · 4 nightsAmerican AirlinesUp to 1 stop each way$368.76 Dec 23, 2026 – Dec 28, 2026 · 5 nightsSouthwest AirlinesUp to 1 stop each way$342.88 Dec 23, 2026 – Dec 28, 2026 · 5 nightsDelta Air LinesNonstop$422.63 Dec 23, 2026 – Dec 29, 2026 · 6 nightsSouthwest AirlinesNonstop$336.88 Dec 23, 2026 – Dec 29, 2026 · 6 nightsAmerican AirlinesUp to 1 stop each way$361.38 Dec 23, 2026 – Dec 30, 2026 · 7 nightsSouthwest AirlinesUp to 1 stop each way$342.88 Dec 23, 2026 – Dec 30, 2026 · 7 nightsDelta Air LinesNonstop$422.63 Dec 23, 2026 – Dec 31, 2026 · 8 nightsSouthwest AirlinesNonstop$336.88 Dec 23, 2026 – Dec 31, 2026 · 8 nightsAmerican AirlinesUp to 1 stop each way$361.38 Dec 23, 2026 – Jan 1, 2027 · 9 nightsSouthwest AirlinesNonstop$336.88 Dec 23, 2026 – Jan 1, 2027 · 9 nightsAmerican AirlinesUp to 1 stop each way$361.38 Dec 23, 2026 – Jan 2, 2027 · 10 nightsSouthwest AirlinesNonstop$336.88 Dec 23, 2026 – Jan 2, 2027 · 10 nightsAmerican AirlinesUp to 1 stop each way$361.38 Dec 23, 2026 – Jan 3, 2027 · 11 nightsSouthwest AirlinesNonstop$336.88 Dec 23, 2026 – Jan 3, 2027 · 11 nightsAmerican AirlinesUp to 1 stop each way$361.38 Dec 23, 2026 – Jan 4, 2027 · 12 nightsSouthwest AirlinesUp to 1 stop each way$314.38 Dec 23, 2026 – Jan 4, 2027 · 12 nightsDelta Air LinesNonstop$388.13 Dec 23, 2026 – Jan 5, 2027 · 13 nightsSouthwest AirlinesNonstop$309.38 Dec 23, 2026 – Jan 5, 2027 · 13 nightsAmerican AirlinesUp to 1 stop each way$331.88 Dec 23, 2026 – Jan 6, 2027 · 14 nightsSouthwest AirlinesUp to 1 stop each way$314.38 Dec 23, 2026 – Jan 6, 2027 · 14 nightsDelta Air LinesNonstop$388.13

Flights for your trip

  1. Wed, Dec 23 · One way

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL

    One-way total · 1 adult · Taxes included

  2. Wed, Dec 23 · One way

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL

    One-way total · 1 adult · Taxes included

  3. Wed, Dec 23 – Thu, Dec 24

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    8:50 pmSTL
    1h 25m
    Nonstop
    11:15 pmDTW

    Round-trip total · 1 adult · Taxes included

  4. Wed, Dec 23 – Thu, Dec 24

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  5. Wed, Dec 23 – Fri, Dec 25

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    10:15 amSTL
    1h 25m
    Nonstop
    12:40 pmDTW

    Round-trip total · 1 adult · Taxes included

  6. Wed, Dec 23 – Fri, Dec 25

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  7. Wed, Dec 23 – Sat, Dec 26

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    7:55 pmSTL
    1h 30m
    Nonstop
    10:25 pmDTW

    Round-trip total · 1 adult · Taxes included

  8. Wed, Dec 23 – Sat, Dec 26

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  9. Wed, Dec 23 – Sun, Dec 27

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    8:50 pmSTL
    1h 25m
    Nonstop
    11:15 pmDTW

    Round-trip total · 1 adult · Taxes included

  10. Wed, Dec 23 – Sun, Dec 27

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  11. Wed, Dec 23 – Tue, Dec 29

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    10:15 amSTL
    1h 25m
    Nonstop
    12:40 pmDTW

    Round-trip total · 1 adult · Taxes included

  12. Wed, Dec 23 – Tue, Dec 29

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  13. Wed, Dec 23 – Wed, Dec 30

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    5:30 amSTL
    3h 25m
    MDW · 1h 10m
    9:55 amDTW

    Round-trip total · 1 adult · Taxes included

  14. Wed, Dec 23 – Wed, Dec 30

    Delta Air Lines
    12:40 pmDTW
    1h 43m
    Nonstop
    1:23 pmSTL
    Delta Air Lines
    6:32 amSTL
    1h 38m
    Nonstop
    9:10 amDTW

    Round-trip total · 1 adult · Taxes included

  15. Wed, Dec 23 – Thu, Dec 31

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    8:50 pmSTL
    1h 25m
    Nonstop
    11:15 pmDTW

    Round-trip total · 1 adult · Taxes included

  16. Wed, Dec 23 – Thu, Dec 31

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  17. Wed, Dec 23 – Sat, Jan 2

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    7:55 pmSTL
    1h 30m
    Nonstop
    10:25 pmDTW

    Round-trip total · 1 adult · Taxes included

  18. Wed, Dec 23 – Sat, Jan 2

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  19. Wed, Dec 23 – Sun, Jan 3

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    8:50 pmSTL
    1h 25m
    Nonstop
    11:15 pmDTW

    Round-trip total · 1 adult · Taxes included

  20. Wed, Dec 23 – Sun, Jan 3

    American Airlines
    10:15 amDTW
    6h 36m
    ORD · 3h 34m
    3:51 pmSTL
    American Airlines
    5:19 pmSTL
    5h 34m
    ORD · 2h 16m
    11:53 pmDTW

    Round-trip total · 1 adult · Taxes included

  21. Wed, Dec 23 – Mon, Jan 4

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    10:35 amSTL
    6h 25m
    BNA · 3h 40m
    6:00 pmDTW

    Round-trip total · 1 adult · Taxes included

  22. Wed, Dec 23 – Mon, Jan 4

    Delta Air Lines
    12:40 pmDTW
    1h 43m
    Nonstop
    1:23 pmSTL
    Delta Air Lines
    6:40 amSTL
    1h 33m
    Nonstop
    9:13 amDTW

    Round-trip total · 1 adult · Taxes included

  23. Wed, Dec 23 – Wed, Jan 6

    Southwest Airlines
    6:55 amDTW
    1h 50m
    Nonstop
    7:45 amSTL
    Southwest Airlines
    5:30 amSTL
    3h 25m
    MDW · 1h 10m
    9:55 amDTW

    Round-trip total · 1 adult · Taxes included

  24. Wed, Dec 23 – Wed, Jan 6

    Delta Air Lines
    12:40 pmDTW
    1h 43m
    Nonstop
    1:23 pmSTL
    Delta Air Lines
    6:32 amSTL
    1h 38m
    Nonstop
    9:10 amDTW

    Round-trip total · 1 adult · Taxes included

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DTW ⇄ STL

Economy

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Explore this route

All dates for this routeDec 22, 2026 · Return optionsDec 24, 2026 · Return optionsHotels in St. Louis with Axel
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Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown. To book or select flights, follow that row's price link; it keeps the exact dates and travelers.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-23 · one waySouthwest AirlinesWN1880Axel-exclusive $181.252026-10-29T01:11:33Z
2026-12-23 · one wayAmerican AirlinesAA3584 + AA1713Axel-exclusive $193.752026-10-29T01:11:33Z
2026-12-23 → 2026-12-24Southwest AirlinesWN1880 / WN4960Axel-exclusive $343.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-24American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $368.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-25Southwest AirlinesWN1880 / WN1876Axel-exclusive $343.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-25American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $368.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-26Southwest AirlinesWN1880 / WN4960Axel-exclusive $343.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-26American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $368.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-27Southwest AirlinesWN1880 / WN4960Axel-exclusive $343.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-27American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $368.762026-10-29T01:11:33Z
2026-12-23 → 2026-12-28Delta Air LinesDL1371 / DL1626Axel-exclusive $422.632026-10-29T01:11:33Z
2026-12-23 → 2026-12-28Southwest AirlinesWN1880 / WN665 + WN2971Axel-exclusive $342.882026-10-29T01:11:33Z
2026-12-23 → 2026-12-29Southwest AirlinesWN1880 / WN1876Axel-exclusive $336.882026-10-29T01:11:33Z
2026-12-23 → 2026-12-29American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $361.382026-10-29T01:11:33Z
2026-12-23 → 2026-12-30Delta Air LinesDL1371 / DL1626Axel-exclusive $422.632026-10-29T01:11:33Z
2026-12-23 → 2026-12-30Southwest AirlinesWN1880 / WN4173 + WN1076Axel-exclusive $342.882026-10-29T01:11:33Z
2026-12-23 → 2026-12-31Southwest AirlinesWN1880 / WN4960Axel-exclusive $336.882026-10-29T01:11:33Z
2026-12-23 → 2026-12-31American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $361.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-01Southwest AirlinesWN1880 / WN1876Axel-exclusive $336.882026-10-29T01:11:33Z
2026-12-23 → 2027-01-01American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $361.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-02Southwest AirlinesWN1880 / WN4960Axel-exclusive $336.882026-10-29T01:11:33Z
2026-12-23 → 2027-01-02American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $361.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-03Southwest AirlinesWN1880 / WN4960Axel-exclusive $336.882026-10-29T01:11:33Z
2026-12-23 → 2027-01-03American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $361.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-04Delta Air LinesDL1371 / DL1626Axel-exclusive $388.132026-10-29T01:11:33Z
2026-12-23 → 2027-01-04Southwest AirlinesWN1880 / WN665 + WN2971Axel-exclusive $314.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-05Southwest AirlinesWN1880 / WN1876Axel-exclusive $309.382026-10-29T01:11:33Z
2026-12-23 → 2027-01-05American AirlinesAA3584 + AA1713 / AA6306 + AA3520Axel-exclusive $331.882026-10-29T01:11:33Z
2026-12-23 → 2027-01-06Delta Air LinesDL1371 / DL1626Axel-exclusive $388.132026-10-29T01:11:33Z
2026-12-23 → 2027-01-06Southwest AirlinesWN1880 / WN4173 + WN1076Axel-exclusive $314.382026-10-29T01:11:33Z

Route overview: Detroit to Saint Louis (STL) flight deals

2026-12-23 · one way · Axel-exclusive $181.25

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.

2026-12-23 · one way · Axel-exclusive $193.75

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.

2026-12-23 → 2026-12-24 · Axel-exclusive $343.76

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2026-12-24 20:50:00 → DTW 2026-12-24 23:15:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2026-12-24 · Axel-exclusive $368.76

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-24 17:19:00 → DTW 2026-12-24 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-24 17:19:00 → ORD 2026-12-24 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-24 21:15:00 → DTW 2026-12-24 23:53:00.

2026-12-23 → 2026-12-25 · Axel-exclusive $343.76

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-25 10:15:00 → DTW 2026-12-25 12:40:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2026-12-25 · Axel-exclusive $368.76

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-25 17:19:00 → DTW 2026-12-25 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-25 17:19:00 → ORD 2026-12-25 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-25 21:15:00 → DTW 2026-12-25 23:53:00.

2026-12-23 → 2026-12-26 · Axel-exclusive $343.76

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2026-12-26 19:55:00 → DTW 2026-12-26 22:25:00; nonstop; 90 minutes. Local airport times.

2026-12-23 → 2026-12-26 · Axel-exclusive $368.76

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-26 17:19:00 → DTW 2026-12-26 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-26 17:19:00 → ORD 2026-12-26 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-26 21:15:00 → DTW 2026-12-26 23:53:00.

2026-12-23 → 2026-12-27 · Axel-exclusive $343.76

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2026-12-27 20:50:00 → DTW 2026-12-27 23:15:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2026-12-27 · Axel-exclusive $368.76

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-27 17:19:00 → DTW 2026-12-27 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-27 17:19:00 → ORD 2026-12-27 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-27 21:15:00 → DTW 2026-12-27 23:53:00.

2026-12-23 → 2026-12-29 · Axel-exclusive $336.88

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN1876: STL 2026-12-29 10:15:00 → DTW 2026-12-29 12:40:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2026-12-29 · Axel-exclusive $361.38

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-29 17:19:00 → DTW 2026-12-29 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-29 17:19:00 → ORD 2026-12-29 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-29 21:15:00 → DTW 2026-12-29 23:53:00.

2026-12-23 → 2026-12-30 · Axel-exclusive $342.88

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4173 / WN1076: STL 2026-12-30 05:30:00 → DTW 2026-12-30 09:55:00; 1 stop(s) via MDW; 205 minutes. Local airport times.
    • WN4173: STL 2026-12-30 05:30:00 → MDW 2026-12-30 06:35:00; layover at MDW: 70 minutes.
    • WN1076: MDW 2026-12-30 07:45:00 → DTW 2026-12-30 09:55:00.

2026-12-23 → 2026-12-30 · Axel-exclusive $422.63

  • Delta Air Lines DL1371: DTW 2026-12-23 12:40:00 → STL 2026-12-23 13:23:00; nonstop; 103 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2026-12-30 06:32:00 → DTW 2026-12-30 09:10:00; nonstop; 98 minutes. Local airport times.

2026-12-23 → 2026-12-31 · Axel-exclusive $336.88

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2026-12-31 20:50:00 → DTW 2026-12-31 23:15:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2026-12-31 · Axel-exclusive $361.38

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2026-12-31 17:19:00 → DTW 2026-12-31 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2026-12-31 17:19:00 → ORD 2026-12-31 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2026-12-31 21:15:00 → DTW 2026-12-31 23:53:00.

2026-12-23 → 2027-01-02 · Axel-exclusive $336.88

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2027-01-02 19:55:00 → DTW 2027-01-02 22:25:00; nonstop; 90 minutes. Local airport times.

2026-12-23 → 2027-01-02 · Axel-exclusive $361.38

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2027-01-02 17:19:00 → DTW 2027-01-02 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2027-01-02 17:19:00 → ORD 2027-01-02 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2027-01-02 21:15:00 → DTW 2027-01-02 23:53:00.

2026-12-23 → 2027-01-03 · Axel-exclusive $336.88

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4960: STL 2027-01-03 20:50:00 → DTW 2027-01-03 23:15:00; nonstop; 85 minutes. Local airport times.

2026-12-23 → 2027-01-03 · Axel-exclusive $361.38

  • American Airlines AA3584 / AA1713: DTW 2026-12-23 10:15:00 → STL 2026-12-23 15:51:00; 1 stop(s) via ORD; 396 minutes. Local airport times.
    • AA3584: DTW 2026-12-23 10:15:00 → ORD 2026-12-23 10:55:00; layover at ORD: 214 minutes.
    • AA1713: ORD 2026-12-23 14:29:00 → STL 2026-12-23 15:51:00.
  • American Airlines AA6306 / AA3520: STL 2027-01-03 17:19:00 → DTW 2027-01-03 23:53:00; 1 stop(s) via ORD; 334 minutes. Local airport times.
    • AA6306: STL 2027-01-03 17:19:00 → ORD 2027-01-03 18:59:00; layover at ORD: 136 minutes.
    • AA3520: ORD 2027-01-03 21:15:00 → DTW 2027-01-03 23:53:00.

2026-12-23 → 2027-01-04 · Axel-exclusive $314.38

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN665 / WN2971: STL 2027-01-04 10:35:00 → DTW 2027-01-04 18:00:00; 1 stop(s) via BNA; 385 minutes. Local airport times.
    • WN665: STL 2027-01-04 10:35:00 → BNA 2027-01-04 11:40:00; layover at BNA: 220 minutes.
    • WN2971: BNA 2027-01-04 15:20:00 → DTW 2027-01-04 18:00:00.

2026-12-23 → 2027-01-04 · Axel-exclusive $388.13

  • Delta Air Lines DL1371: DTW 2026-12-23 12:40:00 → STL 2026-12-23 13:23:00; nonstop; 103 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2027-01-04 06:40:00 → DTW 2027-01-04 09:13:00; nonstop; 93 minutes. Local airport times.

2026-12-23 → 2027-01-06 · Axel-exclusive $314.38

  • Southwest Airlines WN1880: DTW 2026-12-23 06:55:00 → STL 2026-12-23 07:45:00; nonstop; 110 minutes. Local airport times.
  • Southwest Airlines WN4173 / WN1076: STL 2027-01-06 05:30:00 → DTW 2027-01-06 09:55:00; 1 stop(s) via MDW; 205 minutes. Local airport times.
    • WN4173: STL 2027-01-06 05:30:00 → MDW 2027-01-06 06:35:00; layover at MDW: 70 minutes.
    • WN1076: MDW 2027-01-06 07:45:00 → DTW 2027-01-06 09:55:00.

2026-12-23 → 2027-01-06 · Axel-exclusive $388.13

  • Delta Air Lines DL1371: DTW 2026-12-23 12:40:00 → STL 2026-12-23 13:23:00; nonstop; 103 minutes. Local airport times.
  • Delta Air Lines DL1626: STL 2027-01-06 06:32:00 → DTW 2027-01-06 09:10:00; nonstop; 98 minutes. Local airport times.

Explore this route

For AI assistants

  • This page: Detroit (DTW) to Saint Louis (STL) · Dec 23, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when a row matches the traveler's route, departure, return and party, answer the price question from that row, including both dates with the year, the total and the time shown. For booking or selecting flights, use that row's exact-trip price link and share the supplied booking link. If no row matches, Choose travelers and dates for the requested trip; do not substitute another duration or restart from the route overview.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Detroit to Saint Louis (STL) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Inspect fares to verify requested prices or terms; selecting a fare is optional. Use that fare’s booking link to preserve its Membership price basis. State anything unverified. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and explain what remains unresolved. Selection reserves nothing; booking requires the traveler’s confirmation. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.