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Route overview: Des Moines to Chicago (ORD) flight deals

Des Moines → Chicago

Nov 22, 2026 · choose your return date

DSM → ORD1 adulteconomyOne way and round trips

30 flight options · 2 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

November 2026

Nov 22, 2026 · One wayAmerican AirlinesNonstop$145.00 Nov 22, 2026 · One wayUnited AirlinesNonstop$150.00 Nov 22, 2026 – Nov 23, 2026 · 1 nightAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Nov 23, 2026 · 1 nightUnited AirlinesNonstop$285.00 Nov 22, 2026 – Nov 24, 2026 · 2 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 24, 2026 · 2 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 25, 2026 · 3 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 25, 2026 · 3 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 26, 2026 · 4 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 26, 2026 · 4 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 27, 2026 · 5 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 27, 2026 · 5 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 28, 2026 · 6 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 28, 2026 · 6 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 29, 2026 · 7 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 29, 2026 · 7 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Nov 30, 2026 · 8 nightsAmerican AirlinesNonstop$323.13 Nov 22, 2026 – Nov 30, 2026 · 8 nightsUnited AirlinesNonstop$334.88 Nov 22, 2026 – Dec 1, 2026 · 9 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 1, 2026 · 9 nightsUnited AirlinesNonstop$285.00 Nov 22, 2026 – Dec 2, 2026 · 10 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 2, 2026 · 10 nightsUnited AirlinesNonstop$285.00 Nov 22, 2026 – Dec 3, 2026 · 11 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 3, 2026 · 11 nightsUnited AirlinesNonstop$285.00 Nov 22, 2026 – Dec 4, 2026 · 12 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 4, 2026 · 12 nightsUnited AirlinesNonstop$285.00 Nov 22, 2026 – Dec 5, 2026 · 13 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 5, 2026 · 13 nightsUnited AirlinesNonstop$285.00 Nov 22, 2026 – Dec 6, 2026 · 14 nightsAmerican AirlinesNonstop$275.00 Nov 22, 2026 – Dec 6, 2026 · 14 nightsUnited AirlinesNonstop$285.00

Flights for your trip

  1. Sun, Nov 22 · One way

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  2. Sun, Nov 22 · One way

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  3. Sun, Nov 22 – Mon, Nov 23

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    7:14 amORD
    1h 32m
    Nonstop
    8:46 amDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  4. Sun, Nov 22 – Mon, Nov 23

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    4:00 pmORD
    1h 28m
    Nonstop
    5:28 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  5. Sun, Nov 22 – Tue, Nov 24

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    7:14 amORD
    1h 32m
    Nonstop
    8:46 amDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  6. Sun, Nov 22 – Tue, Nov 24

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    4:00 pmORD
    1h 28m
    Nonstop
    5:28 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  7. Sun, Nov 22 – Wed, Nov 25

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    7:14 amORD
    1h 32m
    Nonstop
    8:46 amDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  8. Sun, Nov 22 – Wed, Nov 25

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    4:00 pmORD
    1h 28m
    Nonstop
    5:28 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  9. Sun, Nov 22 – Thu, Nov 26

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    10:45 pmORD
    1h 34m
    Nonstop
    12:19 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  10. Sun, Nov 22 – Thu, Nov 26

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    4:00 pmORD
    1h 28m
    Nonstop
    5:28 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  11. Sun, Nov 22 – Sat, Nov 28

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    11:00 pmORD
    1h 43m
    Nonstop
    12:43 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  12. Sun, Nov 22 – Sat, Nov 28

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  13. Sun, Nov 22 – Sun, Nov 29

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    10:45 pmORD
    1h 34m
    Nonstop
    12:19 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  14. Sun, Nov 22 – Sun, Nov 29

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  15. Sun, Nov 22 – Mon, Nov 30

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    10:45 pmORD
    1h 34m
    Nonstop
    12:19 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  16. Sun, Nov 22 – Mon, Nov 30

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  17. Sun, Nov 22 – Wed, Dec 2

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    7:14 amORD
    1h 32m
    Nonstop
    8:46 amDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  18. Sun, Nov 22 – Wed, Dec 2

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  19. Sun, Nov 22 – Thu, Dec 3

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    10:45 pmORD
    1h 34m
    Nonstop
    12:19 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  20. Sun, Nov 22 – Thu, Dec 3

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  21. Sun, Nov 22 – Fri, Dec 4

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    5:21 pmORD
    1h 40m
    Nonstop
    7:01 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  22. Sun, Nov 22 – Fri, Dec 4

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  23. Sun, Nov 22 – Sun, Dec 6

    American Airlines
    1:58 pmDSM
    1h 44m
    Nonstop
    3:42 pmORD
    American Airlines
    10:45 pmORD
    1h 34m
    Nonstop
    12:19 am+1DSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  24. Sun, Nov 22 – Sun, Dec 6

    United Airlines
    8:00 amDSM
    1h 40m
    Nonstop
    9:40 amORD
    United Airlines
    7:55 pmORD
    1h 30m
    Nonstop
    9:25 pmDSM

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

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1 of 24

Make this trip yours

DSM ⇄ ORD

Economy

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Explore this route

All dates for this routeNov 21, 2026 · Return optionsNov 23, 2026 · Return optionsHotels in Chicago with Axel
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-22 · one wayAmerican AirlinesAA6229Axel-exclusive $145.002026-10-29T01:08:44Z
2026-11-22 · one wayUnited AirlinesUA2668Axel-exclusive $150.002026-10-29T01:08:44Z
2026-11-22 → 2026-11-23American AirlinesAA6229 / AA6284Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-11-23United AirlinesUA2668 / UA551Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-11-24American AirlinesAA6229 / AA6284Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-24United AirlinesUA2668 / UA551Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-25American AirlinesAA6229 / AA6284Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-25United AirlinesUA2668 / UA551Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-26American AirlinesAA6229 / AA4548Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-26United AirlinesUA2668 / UA551Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-27American AirlinesAA6229 / AA4548Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-27United AirlinesUA2668 / UA551Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-28American AirlinesAA6229 / AA3816Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-28United AirlinesUA2668 / UA1839Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-29American AirlinesAA6229 / AA4548Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-29United AirlinesUA2668 / UA1839Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-11-30American AirlinesAA6229 / AA4548Axel-exclusive $323.132026-10-29T01:08:44Z
2026-11-22 → 2026-11-30United AirlinesUA2668 / UA1839Axel-exclusive $334.882026-10-29T01:08:44Z
2026-11-22 → 2026-12-01American AirlinesAA6229 / AA4711Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-01United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-02American AirlinesAA6229 / AA6284Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-02United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-03American AirlinesAA6229 / AA4548Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-03United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-04American AirlinesAA6229 / AA4711Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-04United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-05American AirlinesAA6229 / AA3816Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-05United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-06American AirlinesAA6229 / AA4548Axel-exclusive $275.002026-10-29T01:08:44Z
2026-11-22 → 2026-12-06United AirlinesUA2668 / UA1839Axel-exclusive $285.002026-10-29T01:08:44Z

Route overview: Des Moines to Chicago (ORD) flight deals

2026-11-22 · one way · Axel-exclusive $145.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.

2026-11-22 · one way · Axel-exclusive $150.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.

2026-11-22 → 2026-11-23 · Axel-exclusive $275.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA6284: ORD 2026-11-23 07:14:00 → DSM 2026-11-23 08:46:00; nonstop; 92 minutes. Local airport times.

2026-11-22 → 2026-11-23 · Axel-exclusive $285.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA551: ORD 2026-11-23 16:00:00 → DSM 2026-11-23 17:28:00; nonstop; 88 minutes. Local airport times.

2026-11-22 → 2026-11-24 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA6284: ORD 2026-11-24 07:14:00 → DSM 2026-11-24 08:46:00; nonstop; 92 minutes. Local airport times.

2026-11-22 → 2026-11-24 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA551: ORD 2026-11-24 16:00:00 → DSM 2026-11-24 17:28:00; nonstop; 88 minutes. Local airport times.

2026-11-22 → 2026-11-25 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA6284: ORD 2026-11-25 07:14:00 → DSM 2026-11-25 08:46:00; nonstop; 92 minutes. Local airport times.

2026-11-22 → 2026-11-25 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA551: ORD 2026-11-25 16:00:00 → DSM 2026-11-25 17:28:00; nonstop; 88 minutes. Local airport times.

2026-11-22 → 2026-11-26 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4548: ORD 2026-11-26 22:45:00 → DSM 2026-11-27 00:19:00; nonstop; 94 minutes. Local airport times.

2026-11-22 → 2026-11-26 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA551: ORD 2026-11-26 16:00:00 → DSM 2026-11-26 17:28:00; nonstop; 88 minutes. Local airport times.

2026-11-22 → 2026-11-28 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA3816: ORD 2026-11-28 23:00:00 → DSM 2026-11-29 00:43:00; nonstop; 103 minutes. Local airport times.

2026-11-22 → 2026-11-28 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-11-28 19:55:00 → DSM 2026-11-28 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-11-29 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4548: ORD 2026-11-29 22:45:00 → DSM 2026-11-30 00:19:00; nonstop; 94 minutes. Local airport times.

2026-11-22 → 2026-11-29 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-11-29 19:55:00 → DSM 2026-11-29 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-11-30 · Axel-exclusive $323.13

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4548: ORD 2026-11-30 22:45:00 → DSM 2026-12-01 00:19:00; nonstop; 94 minutes. Local airport times.

2026-11-22 → 2026-11-30 · Axel-exclusive $334.88

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-11-30 19:55:00 → DSM 2026-11-30 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-12-02 · Axel-exclusive $275.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA6284: ORD 2026-12-02 07:14:00 → DSM 2026-12-02 08:46:00; nonstop; 92 minutes. Local airport times.

2026-11-22 → 2026-12-02 · Axel-exclusive $285.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-12-02 19:55:00 → DSM 2026-12-02 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-12-03 · Axel-exclusive $275.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4548: ORD 2026-12-03 22:45:00 → DSM 2026-12-04 00:19:00; nonstop; 94 minutes. Local airport times.

2026-11-22 → 2026-12-03 · Axel-exclusive $285.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-12-03 19:55:00 → DSM 2026-12-03 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-12-04 · Axel-exclusive $275.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4711: ORD 2026-12-04 17:21:00 → DSM 2026-12-04 19:01:00; nonstop; 100 minutes. Local airport times.

2026-11-22 → 2026-12-04 · Axel-exclusive $285.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-12-04 19:55:00 → DSM 2026-12-04 21:25:00; nonstop; 90 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $275.00

  • American Airlines AA6229: DSM 2026-11-22 13:58:00 → ORD 2026-11-22 15:42:00; nonstop; 104 minutes. Local airport times.
  • American Airlines AA4548: ORD 2026-12-06 22:45:00 → DSM 2026-12-07 00:19:00; nonstop; 94 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $285.00

  • United Airlines UA2668: DSM 2026-11-22 08:00:00 → ORD 2026-11-22 09:40:00; nonstop; 100 minutes. Local airport times.
  • United Airlines UA1839: ORD 2026-12-06 19:55:00 → DSM 2026-12-06 21:25:00; nonstop; 90 minutes. Local airport times.

Explore this route

For AI assistants

  • This page: Des Moines (DSM) to Chicago (ORD) · Nov 22, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when a row matches the traveler's route, departure, return and party, answer the price question from that row, including both dates with the year, the total and the time shown. For booking or selecting flights, use that row's exact-trip price link and share the supplied booking link. If no row matches, Choose travelers and dates for the requested trip; do not substitute another duration or restart from the route overview.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Des Moines to Chicago (ORD) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.