Knoxville (TYS) to Detroit (DTW), Dec 18–20, 2026: from $165 one way

Knoxville (TYS) to Detroit (DTW), Dec 18–20, 2026: from $165 one way on Axel, checked Oct 29, 2026. Lowest published fare: $165 one way, Axel-exclusive, Southwest Airlines, 1 stop, Dec 18, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Knoxville to Detroit (DTW) flight deals

2026-12-18 · one way · Axel-exclusive $215.00

• Delta Air Lines DL5091: TYS 2026-12-18 11:49:00 → DTW 2026-12-18 13:39:00; nonstop; 110 minutes. Local airport times.

2026-12-18 · one way · Axel-exclusive $165.00

• Southwest Airlines WN463 / WN1991: TYS 2026-12-18 17:15:00 → DTW 2026-12-18 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
  • WN463: TYS 2026-12-18 17:15:00 → BNA 2026-12-18 17:15:00; layover at BNA: 80 minutes.
  • WN1991: BNA 2026-12-18 18:35:00 → DTW 2026-12-18 21:25:00.

2026-12-18 · one way · Axel-exclusive $175.00

• American Airlines AA5118 / AA2376: TYS 2026-12-18 08:50:00 → DTW 2026-12-18 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
  • AA5118: TYS 2026-12-18 08:50:00 → CLT 2026-12-18 10:17:00; layover at CLT: 218 minutes.
  • AA2376: CLT 2026-12-18 13:55:00 → DTW 2026-12-18 15:43:00.

2026-12-18 · one way · Axel-exclusive $180.00

• United Airlines UA5478 / UA3491: TYS 2026-12-18 17:40:00 → DTW 2026-12-18 23:44:00; 1 stop(s) via ORD; 364 minutes. Local airport times.
  • UA5478: TYS 2026-12-18 17:40:00 → ORD 2026-12-18 18:43:00; layover at ORD: 157 minutes.
  • UA3491: ORD 2026-12-18 21:20:00 → DTW 2026-12-18 23:44:00.

2026-12-19 · one way · Axel-exclusive $279.50

• Delta Air Lines DL5091: TYS 2026-12-19 11:49:00 → DTW 2026-12-19 13:39:00; nonstop; 110 minutes. Local airport times.

2026-12-20 · one way · Axel-exclusive $279.50

• Delta Air Lines DL5091: TYS 2026-12-20 11:49:00 → DTW 2026-12-20 13:39:00; nonstop; 110 minutes. Local airport times.

2026-12-18 · one way · Axel-exclusive $215.00

• Delta Air Lines DL4697: TYS 2026-12-18 17:10:00 → DTW 2026-12-18 18:57:00; nonstop; 107 minutes. Local airport times.

2026-12-20 · one way · Axel-exclusive $279.50

• Delta Air Lines DL4697: TYS 2026-12-20 17:10:00 → DTW 2026-12-20 18:57:00; nonstop; 107 minutes. Local airport times.

2026-12-19 · one way · Axel-exclusive $279.50

• Delta Air Lines DL4697: TYS 2026-12-19 17:10:00 → DTW 2026-12-19 18:57:00; nonstop; 107 minutes. Local airport times.

2026-12-18 · one way · Axel-exclusive $180.00

• United Airlines UA4848 / UA6246: TYS 2026-12-18 14:07:00 → DTW 2026-12-18 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4848: TYS 2026-12-18 14:07:00 → IAD 2026-12-18 15:50:00; layover at IAD: 95 minutes.
  • UA6246: IAD 2026-12-18 17:25:00 → DTW 2026-12-18 19:09:00.

2026-12-18 · one way · Axel-exclusive $185.00

• Delta Air Lines DL4666 / DL1031: TYS 2026-12-18 10:35:00 → DTW 2026-12-18 16:05:00; 1 stop(s) via ATL; 330 minutes. Local airport times.
  • DL4666: TYS 2026-12-18 10:35:00 → ATL 2026-12-18 11:36:00; layover at ATL: 152 minutes.
  • DL1031: ATL 2026-12-18 14:08:00 → DTW 2026-12-18 16:05:00.

2026-12-20 · one way · Axel-exclusive $214.50

• Southwest Airlines WN463 / WN1991: TYS 2026-12-20 17:15:00 → DTW 2026-12-20 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
  • WN463: TYS 2026-12-20 17:15:00 → BNA 2026-12-20 17:15:00; layover at BNA: 80 minutes.
  • WN1991: BNA 2026-12-20 18:35:00 → DTW 2026-12-20 21:25:00.

2026-12-19 · one way · Axel-exclusive $214.50

• Southwest Airlines WN463 / WN1991: TYS 2026-12-19 17:15:00 → DTW 2026-12-19 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
  • WN463: TYS 2026-12-19 17:15:00 → BNA 2026-12-19 17:15:00; layover at BNA: 80 minutes.
  • WN1991: BNA 2026-12-19 18:35:00 → DTW 2026-12-19 21:25:00.

2026-12-19 · one way · Axel-exclusive $227.50

• American Airlines AA5118 / AA2376: TYS 2026-12-19 08:50:00 → DTW 2026-12-19 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
  • AA5118: TYS 2026-12-19 08:50:00 → CLT 2026-12-19 10:17:00; layover at CLT: 218 minutes.
  • AA2376: CLT 2026-12-19 13:55:00 → DTW 2026-12-19 15:43:00.

2026-12-20 · one way · Axel-exclusive $227.50

• American Airlines AA5118 / AA2376: TYS 2026-12-20 08:50:00 → DTW 2026-12-20 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
  • AA5118: TYS 2026-12-20 08:50:00 → CLT 2026-12-20 10:17:00; layover at CLT: 218 minutes.
  • AA2376: CLT 2026-12-20 13:55:00 → DTW 2026-12-20 15:43:00.

2026-12-19 · one way · Axel-exclusive $234.00

• United Airlines UA5478 / UA3491: TYS 2026-12-19 17:40:00 → DTW 2026-12-19 23:44:00; 1 stop(s) via ORD; 364 minutes. Local airport times.
  • UA5478: TYS 2026-12-19 17:40:00 → ORD 2026-12-19 18:43:00; layover at ORD: 157 minutes.
  • UA3491: ORD 2026-12-19 21:20:00 → DTW 2026-12-19 23:44:00.

2026-12-20 · one way · Axel-exclusive $234.00

• United Airlines UA4848 / UA6246: TYS 2026-12-20 14:07:00 → DTW 2026-12-20 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4848: TYS 2026-12-20 14:07:00 → IAD 2026-12-20 15:50:00; layover at IAD: 95 minutes.
  • UA6246: IAD 2026-12-20 17:25:00 → DTW 2026-12-20 19:09:00.

2026-12-19 · one way · Axel-exclusive $234.00

• United Airlines UA4848 / UA6246: TYS 2026-12-19 14:07:00 → DTW 2026-12-19 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4848: TYS 2026-12-19 14:07:00 → IAD 2026-12-19 15:50:00; layover at IAD: 95 minutes.
  • UA6246: IAD 2026-12-19 17:25:00 → DTW 2026-12-19 19:09:00.

2026-12-20 · one way · Axel-exclusive $234.00

• United Airlines UA5478 / UA3491: TYS 2026-12-20 17:40:00 → DTW 2026-12-20 23:44:00; 1 stop(s) via ORD; 364 minutes. Local airport times.
  • UA5478: TYS 2026-12-20 17:40:00 → ORD 2026-12-20 18:43:00; layover at ORD: 157 minutes.
  • UA3491: ORD 2026-12-20 21:20:00 → DTW 2026-12-20 23:44:00.

2026-12-19 · one way · Axel-exclusive $240.50

• Delta Air Lines DL4666 / DL1031: TYS 2026-12-19 10:35:00 → DTW 2026-12-19 16:05:00; 1 stop(s) via ATL; 330 minutes. Local airport times.
  • DL4666: TYS 2026-12-19 10:35:00 → ATL 2026-12-19 11:36:00; layover at ATL: 152 minutes.
  • DL1031: ATL 2026-12-19 14:08:00 → DTW 2026-12-19 16:05:00.

2026-12-20 · one way · Axel-exclusive $240.50

• Delta Air Lines DL4666 / DL1031: TYS 2026-12-20 10:35:00 → DTW 2026-12-20 16:05:00; 1 stop(s) via ATL; 330 minutes. Local airport times.
  • DL4666: TYS 2026-12-20 10:35:00 → ATL 2026-12-20 11:36:00; layover at ATL: 152 minutes.
  • DL1031: ATL 2026-12-20 14:08:00 → DTW 2026-12-20 16:05:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

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