Tampa (TPA) to Knoxville (TYS), Nov 18–28, 2026: from $356 round trip

Tampa (TPA) to Knoxville (TYS), Nov 18–28, 2026: from $356 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $356 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 18–28, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Knoxville for these trips

Hotels: under a trip, hotels in Knoxville for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Knoxville for these nights (Nov 18–28, 2026 · 10 nights · 2 adults, 1 room): 3★ La Quinta Inn & Suites by Wyndham Knoxville Papermill, $1,743 total · 4★ Graduate by Hilton Knoxville, $6,163 total

All hotels in Knoxville

Route overview: Tampa to Knoxville (TYS) flight deals

2026-11-18 → 2026-11-28 · Axel-exclusive $355.63

• Southwest Airlines WN4205: TPA 2026-11-18 12:40:00 → TYS 2026-11-18 14:30:00; nonstop; 110 minutes. Local airport times.
• Southwest Airlines WN1745 / WN748: TYS 2026-11-28 19:15:00 → TPA 2026-11-29 01:05:00; 1 stop(s) via BNA; 350 minutes. Local airport times.
  • WN1745: TYS 2026-11-28 19:15:00 → BNA 2026-11-28 19:15:00; layover at BNA: 180 minutes.
  • WN748: BNA 2026-11-28 22:15:00 → TPA 2026-11-29 01:05:00.

2026-11-18 → 2026-11-28 · Axel-exclusive $388.13

• American Airlines AA3998 / AA4061: TPA 2026-11-18 13:11:00 → TYS 2026-11-18 20:14:00; 1 stop(s) via MIA; 423 minutes. Local airport times.
  • AA3998: TPA 2026-11-18 13:11:00 → MIA 2026-11-18 14:19:00; layover at MIA: 208 minutes.
  • AA4061: MIA 2026-11-18 17:47:00 → TYS 2026-11-18 20:14:00.
• American Airlines AA3721 / AA1970: TYS 2026-11-28 18:47:00 → TPA 2026-11-28 23:21:00; 1 stop(s) via MIA; 274 minutes. Local airport times.
  • AA3721: TYS 2026-11-28 18:47:00 → MIA 2026-11-28 21:00:00; layover at MIA: 65 minutes.
  • AA1970: MIA 2026-11-28 22:05:00 → TPA 2026-11-28 23:21:00.

2026-11-18 → 2026-11-28 · Axel-exclusive $410.63

• Delta Air Lines DL1099 / DL2571: TPA 2026-11-18 13:20:00 → TYS 2026-11-18 17:22:00; 1 stop(s) via ATL; 242 minutes. Local airport times.
  • DL1099: TPA 2026-11-18 13:20:00 → ATL 2026-11-18 14:55:00; layover at ATL: 90 minutes.
  • DL2571: ATL 2026-11-18 16:25:00 → TYS 2026-11-18 17:22:00.
• Delta Air Lines DL4666 / DL1167: TYS 2026-11-28 10:35:00 → TPA 2026-11-28 16:15:00; 1 stop(s) via ATL; 340 minutes. Local airport times.
  • DL4666: TYS 2026-11-28 10:35:00 → ATL 2026-11-28 11:36:00; layover at ATL: 189 minutes.
  • DL1167: ATL 2026-11-28 14:45:00 → TPA 2026-11-28 16:15:00.

2026-11-18 → 2026-11-28 · Axel-exclusive $365.63

• Southwest Airlines WN523 / WN1875: TPA 2026-11-18 08:05:00 → TYS 2026-11-18 12:20:00; 1 stop(s) via BNA; 255 minutes. Local airport times.
  • WN523: TPA 2026-11-18 08:05:00 → BNA 2026-11-18 09:00:00; layover at BNA: 80 minutes.
  • WN1875: BNA 2026-11-18 10:20:00 → TYS 2026-11-18 12:20:00.
• Southwest Airlines WN1745 / WN748: TYS 2026-11-28 19:15:00 → TPA 2026-11-29 01:05:00; 1 stop(s) via BNA; 350 minutes. Local airport times.
  • WN1745: TYS 2026-11-28 19:15:00 → BNA 2026-11-28 19:15:00; layover at BNA: 180 minutes.
  • WN748: BNA 2026-11-28 22:15:00 → TPA 2026-11-29 01:05:00.

2026-11-18 → 2026-11-28 · Axel-exclusive $388.13

• American Airlines AA1565 / AA6437: TPA 2026-11-18 12:38:00 → TYS 2026-11-18 16:43:00; 1 stop(s) via CLT; 245 minutes. Local airport times.
  • AA1565: TPA 2026-11-18 12:38:00 → CLT 2026-11-18 14:24:00; layover at CLT: 61 minutes.
  • AA6437: CLT 2026-11-18 15:25:00 → TYS 2026-11-18 16:43:00.
• American Airlines AA3721 / AA1970: TYS 2026-11-28 18:47:00 → TPA 2026-11-28 23:21:00; 1 stop(s) via MIA; 274 minutes. Local airport times.
  • AA3721: TYS 2026-11-28 18:47:00 → MIA 2026-11-28 21:00:00; layover at MIA: 65 minutes.
  • AA1970: MIA 2026-11-28 22:05:00 → TPA 2026-11-28 23:21:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 17, 2026 · Return options
• Nov 19, 2026 · Return options
• Hotels in Knoxville with Axel

For AI assistants

• This page: Tampa (TPA) to Knoxville (TYS) · Nov 18, 2026 · return Nov 28, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Knoxville for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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