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Route overview: Tampa to Saint Louis (STL) flight deals

Tampa (TPA) to Saint Louis (STL), Nov 7–11, 2026: from $275 round trip

Tampa (TPA) to Saint Louis (STL), Nov 7–11, 2026: from $275 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $275 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 7–11, 2026, 1 adult, economy, checked Oct 29, 2026.

TPA → STL1 adulteconomyRound trip

6 flight options · 4 airlines

One-stop flights

Sat, Nov 7 – Wed, Nov 11

Southwest Airlines
3:05 pmTPA
5h 25m
MSY · 1h 55m
7:30 pmSTL
Southwest Airlines
5:30 amSTL
5h 30m
MDW · 1h 45m
12:00 pmTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 7 – Wed, Nov 11

American Airlines
2:22 pmTPA
6h 14m
DFW · 1h 33m
7:36 pmSTL
Southwest Airlines
5:30 amSTL
5h 30m
MDW · 1h 45m
12:00 pmTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 7 – Wed, Nov 11

United Airlines
2:16 pmTPA
6h 19m
IAD · 1h 28m
7:35 pmSTL
Southwest Airlines
5:30 amSTL
5h 30m
MDW · 1h 45m
12:00 pmTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 7 – Wed, Nov 11

Delta Air Lines
5:10 amTPA
4h 53m
ATL · 1h 30m
9:03 amSTL
Delta Air Lines
6:00 amSTL
4h 15m
ATL · 1h 4m
11:15 amTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 7 – Wed, Nov 11

Southwest Airlines
3:55 pmTPA
6h 5m
CMH · 2h 20m
9:00 pmSTL
Southwest Airlines
5:30 amSTL
5h 30m
MDW · 1h 45m
12:00 pmTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 7 – Wed, Nov 11

Southwest Airlines
5:45 amTPA
2h 25m
Nonstop
7:10 amSTL
Southwest Airlines
5:30 amSTL
5h 30m
MDW · 1h 45m
12:00 pmTPA

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Hotels for these nights (Nov 7–11, 2026 · 4 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay $277 · 4★ Hilton St. Louis at the Ballpark $444 · 5★ The Ritz-Carlton, St. Louis $2,498

Make this trip yours

TPA ⇄ STL

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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All dates for this routeNov 8, 2026 · Return optionsHotels in St. Louis with Axel
For AI assistants: every fare, every link, instructions

Tampa (TPA) to Saint Louis (STL), Nov 7–11, 2026: from $275 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $275 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 7–11, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-11-07 → 2026-11-11Southwest AirlinesWN3153 + WN3181 / WN4173 + WN150815:05:00→19:30:00 5h 25m 1 stop via MSY · 05:30:00→12:00:00 5h 30m 1 stop via MDWAxel-exclusive $275.002026-10-29T01:30:30Z
2026-11-07 → 2026-11-11American Airlines / Southwest AirlinesAA1743 + AA2246 / WN4173 + WN150814:22:00→19:36:00 6h 14m 1 stop via DFW · 05:30:00→12:00:00 5h 30m 1 stop via MDWAxel-exclusive $302.502026-10-29T01:30:30Z
2026-11-07 → 2026-11-11United Airlines / Southwest AirlinesUA2276 + UA4527 / WN4173 + WN150814:16:00→19:35:00 6h 19m 1 stop via IAD · 05:30:00→12:00:00 5h 30m 1 stop via MDWAxel-exclusive $307.502026-10-29T01:30:30Z
2026-11-07 → 2026-11-11Delta Air LinesDL2743 + DL1571 / DL1524 + DL158705:10:00→09:03:00 4h 53m 1 stop via ATL · 06:00:00→11:15:00 4h 15m 1 stop via ATLAxel-exclusive $350.002026-10-29T01:30:30Z
2026-11-07 → 2026-11-11Southwest AirlinesWN4269 + WN1282 / WN4173 + WN150815:55:00→21:00:00 6h 05m 1 stop via CMH · 05:30:00→12:00:00 5h 30m 1 stop via MDWAxel-exclusive $275.002026-10-29T01:30:30Z
2026-11-07 → 2026-11-11Southwest AirlinesWN2235 / WN4173 + WN150805:45:00→07:10:00 2h 25m nonstop · 05:30:00→12:00:00 5h 30m 1 stop via MDWAxel-exclusive $282.502026-10-29T01:30:30Z

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in St. Louis

Route overview: Tampa to Saint Louis (STL) flight deals

2026-11-07 → 2026-11-11 · Axel-exclusive $275.00

  • Southwest Airlines WN3153 / WN3181: TPA 2026-11-07 15:05:00 → STL 2026-11-07 19:30:00; 1 stop(s) via MSY; 325 minutes. Local airport times.
    • WN3153: TPA 2026-11-07 15:05:00 → MSY 2026-11-07 15:50:00; layover at MSY: 115 minutes.
    • WN3181: MSY 2026-11-07 17:45:00 → STL 2026-11-07 19:30:00.
  • Southwest Airlines WN4173 / WN1508: STL 2026-11-11 05:30:00 → TPA 2026-11-11 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
    • WN4173: STL 2026-11-11 05:30:00 → MDW 2026-11-11 06:35:00; layover at MDW: 105 minutes.
    • WN1508: MDW 2026-11-11 08:20:00 → TPA 2026-11-11 12:00:00.

2026-11-07 → 2026-11-11 · Axel-exclusive $302.50

  • American Airlines AA1743 / AA2246: TPA 2026-11-07 14:22:00 → STL 2026-11-07 19:36:00; 1 stop(s) via DFW; 374 minutes. Local airport times.
    • AA1743: TPA 2026-11-07 14:22:00 → DFW 2026-11-07 16:22:00; layover at DFW: 93 minutes.
    • AA2246: DFW 2026-11-07 17:55:00 → STL 2026-11-07 19:36:00.
  • Southwest Airlines WN4173 / WN1508: STL 2026-11-11 05:30:00 → TPA 2026-11-11 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
    • WN4173: STL 2026-11-11 05:30:00 → MDW 2026-11-11 06:35:00; layover at MDW: 105 minutes.
    • WN1508: MDW 2026-11-11 08:20:00 → TPA 2026-11-11 12:00:00.

2026-11-07 → 2026-11-11 · Axel-exclusive $307.50

  • United Airlines UA2276 / UA4527: TPA 2026-11-07 14:16:00 → STL 2026-11-07 19:35:00; 1 stop(s) via IAD; 379 minutes. Local airport times.
    • UA2276: TPA 2026-11-07 14:16:00 → IAD 2026-11-07 16:32:00; layover at IAD: 88 minutes.
    • UA4527: IAD 2026-11-07 18:00:00 → STL 2026-11-07 19:35:00.
  • Southwest Airlines WN4173 / WN1508: STL 2026-11-11 05:30:00 → TPA 2026-11-11 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
    • WN4173: STL 2026-11-11 05:30:00 → MDW 2026-11-11 06:35:00; layover at MDW: 105 minutes.
    • WN1508: MDW 2026-11-11 08:20:00 → TPA 2026-11-11 12:00:00.

2026-11-07 → 2026-11-11 · Axel-exclusive $350.00

  • Delta Air Lines DL2743 / DL1571: TPA 2026-11-07 05:10:00 → STL 2026-11-07 09:03:00; 1 stop(s) via ATL; 293 minutes. Local airport times.
    • DL2743: TPA 2026-11-07 05:10:00 → ATL 2026-11-07 06:45:00; layover at ATL: 90 minutes.
    • DL1571: ATL 2026-11-07 08:15:00 → STL 2026-11-07 09:03:00.
  • Delta Air Lines DL1524 / DL1587: STL 2026-11-11 06:00:00 → TPA 2026-11-11 11:15:00; 1 stop(s) via ATL; 255 minutes. Local airport times.
    • DL1524: STL 2026-11-11 06:00:00 → ATL 2026-11-11 08:41:00; layover at ATL: 64 minutes.
    • DL1587: ATL 2026-11-11 09:45:00 → TPA 2026-11-11 11:15:00.

2026-11-07 → 2026-11-11 · Axel-exclusive $275.00

  • Southwest Airlines WN4269 / WN1282: TPA 2026-11-07 15:55:00 → STL 2026-11-07 21:00:00; 1 stop(s) via CMH; 365 minutes. Local airport times.
    • WN4269: TPA 2026-11-07 15:55:00 → CMH 2026-11-07 18:10:00; layover at CMH: 140 minutes.
    • WN1282: CMH 2026-11-07 20:30:00 → STL 2026-11-07 21:00:00.
  • Southwest Airlines WN4173 / WN1508: STL 2026-11-11 05:30:00 → TPA 2026-11-11 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
    • WN4173: STL 2026-11-11 05:30:00 → MDW 2026-11-11 06:35:00; layover at MDW: 105 minutes.
    • WN1508: MDW 2026-11-11 08:20:00 → TPA 2026-11-11 12:00:00.

2026-11-07 → 2026-11-11 · Axel-exclusive $282.50

  • Southwest Airlines WN2235: TPA 2026-11-07 05:45:00 → STL 2026-11-07 07:10:00; nonstop; 145 minutes. Local airport times.
  • Southwest Airlines WN4173 / WN1508: STL 2026-11-11 05:30:00 → TPA 2026-11-11 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
    • WN4173: STL 2026-11-11 05:30:00 → MDW 2026-11-11 06:35:00; layover at MDW: 105 minutes.
    • WN1508: MDW 2026-11-11 08:20:00 → TPA 2026-11-11 12:00:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

For AI assistants

  • This page: Tampa (TPA) to Saint Louis (STL) · Nov 7, 2026 · return Nov 11, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Tampa to Saint Louis (STL) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.