Tampa (TPA) to Saint Louis (STL) · Dec 22, 2026 · return Dec 29, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in St. Louis for these nights (Dec 22–29, 2026 · 7 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $475 total · 4★ Hilton St. Louis at the Ballpark, $720 total · 5★ Four Seasons Hotel St Louis, $2,717 total

All hotels in St. Louis

Route overview: Tampa to Saint Louis (STL) flight deals

2026-12-22 → 2026-12-29 · Axel-exclusive $369.75

• Southwest Airlines WN186: TPA 2026-12-22 18:05:00 → STL 2026-12-22 19:40:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $395.75

• American Airlines AA2020 / AA2486: TPA 2026-12-22 06:00:00 → STL 2026-12-22 10:19:00; 1 stop(s) via CLT; 319 minutes. Local airport times.
  • AA2020: TPA 2026-12-22 06:00:00 → CLT 2026-12-22 07:51:00; layover at CLT: 84 minutes.
  • AA2486: CLT 2026-12-22 09:15:00 → STL 2026-12-22 10:19:00.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $402.25

• United Airlines UA2276 / UA4527: TPA 2026-12-22 14:16:00 → STL 2026-12-22 19:35:00; 1 stop(s) via IAD; 379 minutes. Local airport times.
  • UA2276: TPA 2026-12-22 14:16:00 → IAD 2026-12-22 16:32:00; layover at IAD: 88 minutes.
  • UA4527: IAD 2026-12-22 18:00:00 → STL 2026-12-22 19:35:00.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $369.75

• Southwest Airlines WN4283: TPA 2026-12-22 06:10:00 → STL 2026-12-22 07:35:00; nonstop; 145 minutes. Local airport times.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $360.00

• Southwest Airlines WN3153 / WN3181: TPA 2026-12-22 15:05:00 → STL 2026-12-22 19:30:00; 1 stop(s) via MSY; 325 minutes. Local airport times.
  • WN3153: TPA 2026-12-22 15:05:00 → MSY 2026-12-22 15:50:00; layover at MSY: 115 minutes.
  • WN3181: MSY 2026-12-22 17:45:00 → STL 2026-12-22 19:30:00.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $360.00

• Southwest Airlines WN4269 / WN1282: TPA 2026-12-22 15:55:00 → STL 2026-12-22 21:00:00; 1 stop(s) via CMH; 365 minutes. Local airport times.
  • WN4269: TPA 2026-12-22 15:55:00 → CMH 2026-12-22 18:10:00; layover at CMH: 140 minutes.
  • WN1282: CMH 2026-12-22 20:30:00 → STL 2026-12-22 21:00:00.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

2026-12-22 → 2026-12-29 · Axel-exclusive $360.38

• Southwest Airlines WN186: TPA 2026-12-22 16:15:00 → STL 2026-12-22 17:35:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4173 / WN1508: STL 2026-12-29 05:30:00 → TPA 2026-12-29 12:00:00; 1 stop(s) via MDW; 330 minutes. Local airport times.
  • WN4173: STL 2026-12-29 05:30:00 → MDW 2026-12-29 06:35:00; layover at MDW: 105 minutes.
  • WN1508: MDW 2026-12-29 08:20:00 → TPA 2026-12-29 12:00:00.

2026-12-22 → 2026-12-29 · Axel-exclusive $395.75

• American Airlines AA1743 / AA2246: TPA 2026-12-22 14:22:00 → STL 2026-12-22 19:36:00; 1 stop(s) via DFW; 374 minutes. Local airport times.
  • AA1743: TPA 2026-12-22 14:22:00 → DFW 2026-12-22 16:22:00; layover at DFW: 93 minutes.
  • AA2246: DFW 2026-12-22 17:55:00 → STL 2026-12-22 19:36:00.
• Southwest Airlines WN4204: STL 2026-12-29 10:20:00 → TPA 2026-12-29 13:40:00; nonstop; 140 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 21, 2026 · Return options
• Dec 23, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Tampa (TPA) to Saint Louis (STL) · Dec 22, 2026 · return Dec 29, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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