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Route overview: Tampa to San Francisco (SFO) flight deals

Tampa (TPA) to San Francisco (SFO), Dec 21, 2026: round trips from $388, one way from $245

Tampa (TPA) to San Francisco (SFO), Dec 21, 2026: round trips from $388, one way from $245 on Axel, checked Oct 29, 2026. Lowest published fares: $388 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Dec 21, 2026 – Jan 4, 2027; $245 one way, Axel-exclusive, Southwest Airlines, 1 stop, Dec 21, 2026; 1 adult, economy, checked Oct 29, 2026.

TPA → SFO1 adulteconomyOne way and round trips

30 flight options · 2 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Flights for your trip

  1. Mon, Dec 21 · One way

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  2. Mon, Dec 21 · One way

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  3. Mon, Dec 21 – Tue, Dec 22

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    6:10 amSFO
    7h 5m
    DEN · 1h 5m
    4:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  4. Mon, Dec 21 – Tue, Dec 22

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    11:59 pmSFO
    5h 6m
    Nonstop
    8:05 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  5. Mon, Dec 21 – Wed, Dec 23

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    6:10 amSFO
    7h 5m
    DEN · 1h 5m
    4:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  6. Mon, Dec 21 – Wed, Dec 23

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    11:59 pmSFO
    5h 6m
    Nonstop
    8:05 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  7. Mon, Dec 21 – Thu, Dec 24

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    2:00 pmSFO
    7h 10m
    DAL · 1h 20m
    12:10 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  8. Mon, Dec 21 – Thu, Dec 24

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    3:52 pmSFO
    5h 2m
    Nonstop
    11:54 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  9. Mon, Dec 21 – Fri, Dec 25

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    1:05 pmSFO
    7h 10m
    STL · 1h
    11:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  10. Mon, Dec 21 – Fri, Dec 25

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    11:59 pmSFO
    5h 6m
    Nonstop
    8:05 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  11. Mon, Dec 21 – Sun, Dec 27

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    6:10 amSFO
    7h 5m
    DEN · 1h 5m
    4:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  12. Mon, Dec 21 – Sun, Dec 27

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    10:55 pmSFO
    4h 57m
    Nonstop
    6:52 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  13. Mon, Dec 21 – Mon, Dec 28

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    2:00 pmSFO
    7h 10m
    DAL · 1h 20m
    12:10 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  14. Mon, Dec 21 – Mon, Dec 28

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    10:55 pmSFO
    4h 57m
    Nonstop
    6:52 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  15. Mon, Dec 21 – Tue, Dec 29

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    6:10 amSFO
    7h 5m
    DEN · 1h 5m
    4:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  16. Mon, Dec 21 – Tue, Dec 29

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    10:55 pmSFO
    4h 57m
    Nonstop
    6:52 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  17. Mon, Dec 21 – Thu, Dec 31

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    2:00 pmSFO
    7h 10m
    DAL · 1h 20m
    12:10 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  18. Mon, Dec 21 – Thu, Dec 31

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    7:15 amSFO
    5h 4m
    Nonstop
    3:19 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  19. Mon, Dec 21 – Fri, Jan 1

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    1:05 pmSFO
    7h 10m
    STL · 1h
    11:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  20. Mon, Dec 21 – Fri, Jan 1

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    11:59 pmSFO
    5h 6m
    Nonstop
    8:05 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  21. Mon, Dec 21 – Sat, Jan 2

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    6:10 amSFO
    7h 5m
    DEN · 1h 5m
    4:15 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  22. Mon, Dec 21 – Sat, Jan 2

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    7:15 amSFO
    5h 4m
    Nonstop
    3:19 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  23. Mon, Dec 21 – Mon, Jan 4

    Southwest Airlines
    7:10 amTPA
    8h 10m
    PHX · 1h 10m
    12:20 pmSFO
    Southwest Airlines
    2:00 pmSFO
    7h 10m
    DAL · 1h 20m
    12:10 am+1TPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  24. Mon, Dec 21 – Mon, Jan 4

    United Airlines
    6:00 amTPA
    6h 3m
    Nonstop
    9:03 amSFO
    United Airlines
    7:15 amSFO
    5h 4m
    Nonstop
    3:19 pmTPA

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

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1 of 24

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TPA ⇄ SFO

Economy

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Explore this route

All dates for this routeDec 20, 2026 · Return optionsDec 22, 2026 · Return optionsHotels in San Francisco with Axel
For AI assistants: every fare, every link, instructions

Tampa (TPA) to San Francisco (SFO), Dec 21, 2026: round trips from $388, one way from $245 on Axel, checked Oct 29, 2026. Lowest published fares: $388 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Dec 21, 2026 – Jan 4, 2027; $245 one way, Axel-exclusive, Southwest Airlines, 1 stop, Dec 21, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-12-21 · one wayUnited AirlinesUA198606:00:00→09:03:00 6h 03m nonstopAxel-exclusive $294.002026-10-29T01:30:27Z
2026-12-21 · one waySouthwest AirlinesWN4274 + WN32707:10:00→12:20:00 8h 10m 1 stop via PHXAxel-exclusive $245.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-22United AirlinesUA1986 / UA111206:00:00→09:03:00 6h 03m nonstop · 23:59:00→08:05:00 5h 06m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-22Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-23United AirlinesUA1986 / UA111206:00:00→09:03:00 6h 03m nonstop · 23:59:00→08:05:00 5h 06m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-23Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-24United AirlinesUA1986 / UA52006:00:00→09:03:00 6h 03m nonstop · 15:52:00→23:54:00 5h 02m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-24Southwest AirlinesWN4274 + WN327 / WN1982 + WN143407:10:00→12:20:00 8h 10m 1 stop via PHX · 14:00:00→00:10:00 7h 10m 1 stop via DALAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-25United AirlinesUA1986 / UA111206:00:00→09:03:00 6h 03m nonstop · 23:59:00→08:05:00 5h 06m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-25Southwest AirlinesWN4274 + WN327 / WN2989 + WN420607:10:00→12:20:00 8h 10m 1 stop via PHX · 13:05:00→23:15:00 7h 10m 1 stop via STLAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-26United AirlinesUA1986 / UA188506:00:00→09:03:00 6h 03m nonstop · 22:55:00→06:52:00 4h 57m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-26Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-27United AirlinesUA1986 / UA188506:00:00→09:03:00 6h 03m nonstop · 22:55:00→06:52:00 4h 57m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-27Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-28United AirlinesUA1986 / UA188506:00:00→09:03:00 6h 03m nonstop · 22:55:00→06:52:00 4h 57m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-28Southwest AirlinesWN4274 + WN327 / WN1982 + WN143407:10:00→12:20:00 8h 10m 1 stop via PHX · 14:00:00→00:10:00 7h 10m 1 stop via DALAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-29United AirlinesUA1986 / UA188506:00:00→09:03:00 6h 03m nonstop · 22:55:00→06:52:00 4h 57m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-29Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-30United AirlinesUA1986 / UA52006:00:00→09:03:00 6h 03m nonstop · 15:52:00→23:54:00 5h 02m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-30Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-31United AirlinesUA1986 / UA279906:00:00→09:03:00 6h 03m nonstop · 07:15:00→15:19:00 5h 04m nonstopAxel-exclusive $546.002026-10-29T01:30:27Z
2026-12-21 → 2026-12-31Southwest AirlinesWN4274 + WN327 / WN1982 + WN143407:10:00→12:20:00 8h 10m 1 stop via PHX · 14:00:00→00:10:00 7h 10m 1 stop via DALAxel-exclusive $462.002026-10-29T01:30:27Z
2026-12-21 → 2027-01-01United AirlinesUA1986 / UA111206:00:00→09:03:00 6h 03m nonstop · 23:59:00→08:05:00 5h 06m nonstopAxel-exclusive $532.352026-10-29T01:30:27Z
2026-12-21 → 2027-01-01Southwest AirlinesWN4274 + WN327 / WN2989 + WN420607:10:00→12:20:00 8h 10m 1 stop via PHX · 13:05:00→23:15:00 7h 10m 1 stop via STLAxel-exclusive $450.452026-10-29T01:30:27Z
2026-12-21 → 2027-01-02United AirlinesUA1986 / UA279906:00:00→09:03:00 6h 03m nonstop · 07:15:00→15:19:00 5h 04m nonstopAxel-exclusive $532.352026-10-29T01:30:27Z
2026-12-21 → 2027-01-02Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $450.452026-10-29T01:30:27Z
2026-12-21 → 2027-01-03United AirlinesUA1986 / UA279906:00:00→09:03:00 6h 03m nonstop · 07:15:00→15:19:00 5h 04m nonstopAxel-exclusive $532.352026-10-29T01:30:27Z
2026-12-21 → 2027-01-03Southwest AirlinesWN4274 + WN327 / WN4578 + WN48907:10:00→12:20:00 8h 10m 1 stop via PHX · 06:10:00→16:15:00 7h 05m 1 stop via DENAxel-exclusive $450.452026-10-29T01:30:27Z
2026-12-21 → 2027-01-04United AirlinesUA1986 / UA279906:00:00→09:03:00 6h 03m nonstop · 07:15:00→15:19:00 5h 04m nonstopAxel-exclusive $458.252026-10-29T01:30:27Z
2026-12-21 → 2027-01-04Southwest AirlinesWN4274 + WN327 / WN1982 + WN143407:10:00→12:20:00 8h 10m 1 stop via PHX · 14:00:00→00:10:00 7h 10m 1 stop via DALAxel-exclusive $387.752026-10-29T01:30:27Z

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in San Francisco

Route overview: Tampa to San Francisco (SFO) flight deals

2026-12-21 · one way · Axel-exclusive $245.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.

2026-12-21 · one way · Axel-exclusive $294.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.

2026-12-21 → 2026-12-22 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN4578 / WN489: SFO 2026-12-22 06:10:00 → TPA 2026-12-22 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
    • WN4578: SFO 2026-12-22 06:10:00 → DEN 2026-12-22 09:45:00; layover at DEN: 65 minutes.
    • WN489: DEN 2026-12-22 10:50:00 → TPA 2026-12-22 16:15:00.

2026-12-21 → 2026-12-22 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1112: SFO 2026-12-22 23:59:00 → TPA 2026-12-23 08:05:00; nonstop; 306 minutes. Local airport times.

2026-12-21 → 2026-12-23 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN4578 / WN489: SFO 2026-12-23 06:10:00 → TPA 2026-12-23 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
    • WN4578: SFO 2026-12-23 06:10:00 → DEN 2026-12-23 09:45:00; layover at DEN: 65 minutes.
    • WN489: DEN 2026-12-23 10:50:00 → TPA 2026-12-23 16:15:00.

2026-12-21 → 2026-12-23 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1112: SFO 2026-12-23 23:59:00 → TPA 2026-12-24 08:05:00; nonstop; 306 minutes. Local airport times.

2026-12-21 → 2026-12-24 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN1982 / WN1434: SFO 2026-12-24 14:00:00 → TPA 2026-12-25 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
    • WN1982: SFO 2026-12-24 14:00:00 → DAL 2026-12-24 19:30:00; layover at DAL: 80 minutes.
    • WN1434: DAL 2026-12-24 20:50:00 → TPA 2026-12-25 00:10:00.

2026-12-21 → 2026-12-24 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA520: SFO 2026-12-24 15:52:00 → TPA 2026-12-24 23:54:00; nonstop; 302 minutes. Local airport times.

2026-12-21 → 2026-12-25 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN2989 / WN4206: SFO 2026-12-25 13:05:00 → TPA 2026-12-25 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
    • WN2989: SFO 2026-12-25 13:05:00 → STL 2026-12-25 18:55:00; layover at STL: 60 minutes.
    • WN4206: STL 2026-12-25 19:55:00 → TPA 2026-12-25 23:15:00.

2026-12-21 → 2026-12-25 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1112: SFO 2026-12-25 23:59:00 → TPA 2026-12-26 08:05:00; nonstop; 306 minutes. Local airport times.

2026-12-21 → 2026-12-27 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN4578 / WN489: SFO 2026-12-27 06:10:00 → TPA 2026-12-27 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
    • WN4578: SFO 2026-12-27 06:10:00 → DEN 2026-12-27 09:45:00; layover at DEN: 65 minutes.
    • WN489: DEN 2026-12-27 10:50:00 → TPA 2026-12-27 16:15:00.

2026-12-21 → 2026-12-27 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1885: SFO 2026-12-27 22:55:00 → TPA 2026-12-28 06:52:00; nonstop; 297 minutes. Local airport times.

2026-12-21 → 2026-12-28 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN1982 / WN1434: SFO 2026-12-28 14:00:00 → TPA 2026-12-29 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
    • WN1982: SFO 2026-12-28 14:00:00 → DAL 2026-12-28 19:30:00; layover at DAL: 80 minutes.
    • WN1434: DAL 2026-12-28 20:50:00 → TPA 2026-12-29 00:10:00.

2026-12-21 → 2026-12-28 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1885: SFO 2026-12-28 22:55:00 → TPA 2026-12-29 06:52:00; nonstop; 297 minutes. Local airport times.

2026-12-21 → 2026-12-29 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN4578 / WN489: SFO 2026-12-29 06:10:00 → TPA 2026-12-29 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
    • WN4578: SFO 2026-12-29 06:10:00 → DEN 2026-12-29 09:45:00; layover at DEN: 65 minutes.
    • WN489: DEN 2026-12-29 10:50:00 → TPA 2026-12-29 16:15:00.

2026-12-21 → 2026-12-29 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1885: SFO 2026-12-29 22:55:00 → TPA 2026-12-30 06:52:00; nonstop; 297 minutes. Local airport times.

2026-12-21 → 2026-12-31 · Axel-exclusive $462.00

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN1982 / WN1434: SFO 2026-12-31 14:00:00 → TPA 2027-01-01 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
    • WN1982: SFO 2026-12-31 14:00:00 → DAL 2026-12-31 19:30:00; layover at DAL: 80 minutes.
    • WN1434: DAL 2026-12-31 20:50:00 → TPA 2027-01-01 00:10:00.

2026-12-21 → 2026-12-31 · Axel-exclusive $546.00

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA2799: SFO 2026-12-31 07:15:00 → TPA 2026-12-31 15:19:00; nonstop; 304 minutes. Local airport times.

2026-12-21 → 2027-01-01 · Axel-exclusive $450.45

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN2989 / WN4206: SFO 2027-01-01 13:05:00 → TPA 2027-01-01 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
    • WN2989: SFO 2027-01-01 13:05:00 → STL 2027-01-01 18:55:00; layover at STL: 60 minutes.
    • WN4206: STL 2027-01-01 19:55:00 → TPA 2027-01-01 23:15:00.

2026-12-21 → 2027-01-01 · Axel-exclusive $532.35

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA1112: SFO 2027-01-01 23:59:00 → TPA 2027-01-02 08:05:00; nonstop; 306 minutes. Local airport times.

2026-12-21 → 2027-01-02 · Axel-exclusive $450.45

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN4578 / WN489: SFO 2027-01-02 06:10:00 → TPA 2027-01-02 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
    • WN4578: SFO 2027-01-02 06:10:00 → DEN 2027-01-02 09:45:00; layover at DEN: 65 minutes.
    • WN489: DEN 2027-01-02 10:50:00 → TPA 2027-01-02 16:15:00.

2026-12-21 → 2027-01-02 · Axel-exclusive $532.35

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA2799: SFO 2027-01-02 07:15:00 → TPA 2027-01-02 15:19:00; nonstop; 304 minutes. Local airport times.

2026-12-21 → 2027-01-04 · Axel-exclusive $387.75

  • Southwest Airlines WN4274 / WN327: TPA 2026-12-21 07:10:00 → SFO 2026-12-21 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
    • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
    • WN327: PHX 2026-12-21 11:10:00 → SFO 2026-12-21 12:20:00.
  • Southwest Airlines WN1982 / WN1434: SFO 2027-01-04 14:00:00 → TPA 2027-01-05 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
    • WN1982: SFO 2027-01-04 14:00:00 → DAL 2027-01-04 19:30:00; layover at DAL: 80 minutes.
    • WN1434: DAL 2027-01-04 20:50:00 → TPA 2027-01-05 00:10:00.

2026-12-21 → 2027-01-04 · Axel-exclusive $458.25

  • United Airlines UA1986: TPA 2026-12-21 06:00:00 → SFO 2026-12-21 09:03:00; nonstop; 363 minutes. Local airport times.
  • United Airlines UA2799: SFO 2027-01-04 07:15:00 → TPA 2027-01-04 15:19:00; nonstop; 304 minutes. Local airport times.

Explore this route

For AI assistants

  • This page: Tampa (TPA) to San Francisco (SFO) · Dec 21, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Tampa to San Francisco (SFO) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.