Tampa (TPA) to San Francisco (SFO), Apr 27, 2027: round trips from $400, one way from $215

Tampa (TPA) to San Francisco (SFO), Apr 27, 2027: round trips from $400, one way from $215 on Axel, checked Nov 14, 2026. Lowest published fares: $400 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Apr 27–28, 2027; $215 one way, Axel-exclusive, Southwest Airlines, 1 stop, Apr 27, 2027; 1 adult, economy, checked Nov 14, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Apr 27–28, 2027 · 1 night · 2 adults, 1 room): 3★ The Pickwick Hotel, $121 a night · 4★ Hotel Bijou - Union Square, $133 a night · 5★ Taj Campton Place, $343 a night
• Hotels in San Francisco for these nights (Apr 27–29, 2027 · 2 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $122 a night, $244 for 2 nights · 4★ Hotel Bijou - Union Square, $134 a night, $268 for 2 nights · 5★ Taj Campton Place, $338 a night, $675 for 2 nights
• Hotels in San Francisco for these nights (Apr 27–30, 2027 · 3 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $121 a night, $364 for 3 nights · 4★ Hotel Bijou - Union Square, $135 a night, $406 for 3 nights · 5★ Taj Campton Place, $334 a night, $1,002 for 3 nights
• Hotels in San Francisco for these nights (Apr 27 – May 1, 2027 · 4 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $120 a night, $481 for 4 nights · 4★ Hotel Bijou - Union Square, $135 a night, $541 for 4 nights · 5★ Taj Campton Place, $336 a night, $1,343 for 4 nights
• Hotels in San Francisco for these nights (Apr 27 – May 2, 2027 · 5 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $122 a night, $612 for 5 nights · 4★ Hotel Bijou - Union Square, $136 a night, $679 for 5 nights · 5★ Taj Campton Place, $350 a night, $1,750 for 5 nights
• Hotels in San Francisco for these nights (Apr 27 – May 3, 2027 · 6 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $122 a night, $733 for 6 nights · 4★ Hotel Bijou - Union Square, $136 a night, $818 for 6 nights · 5★ Taj Campton Place, $349 a night, $2,091 for 6 nights
• Hotels in San Francisco for these nights (Apr 27 – May 4, 2027 · 7 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $123 a night, $863 for 7 nights · 4★ Hotel Bijou - Union Square, $163 a night, $1,139 for 7 nights · 5★ Taj Campton Place, $346 a night, $2,425 for 7 nights
• Hotels in San Francisco for these nights (Apr 27 – May 5, 2027 · 8 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $138 a night, $1,100 for 8 nights · 4★ Stanford Court San Francisco, $182 a night, $1,456 for 8 nights · 5★ Taj Campton Place, $355 a night, $2,840 for 8 nights
• Hotels in San Francisco for these nights (Apr 27 – May 6, 2027 · 9 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $149 a night, $1,337 for 9 nights · 4★ Stanford Court San Francisco, $187 a night, $1,685 for 9 nights · 5★ Taj Campton Place, $360 a night, $3,236 for 9 nights
• Hotels in San Francisco for these nights (Apr 27 – May 7, 2027 · 10 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $147 a night, $1,473 for 10 nights · 4★ Stanford Court San Francisco, $187 a night, $1,873 for 10 nights · 5★ Taj Campton Place, $359 a night, $3,592 for 10 nights
• Hotels in San Francisco for these nights (Apr 27 – May 8, 2027 · 11 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $146 a night, $1,606 for 11 nights · 4★ Stanford Court San Francisco, $188 a night, $2,068 for 11 nights · 5★ Taj Campton Place, $358 a night, $3,936 for 11 nights
• Hotels in San Francisco for these nights (Apr 27 – May 9, 2027 · 12 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $145 a night, $1,744 for 12 nights · 4★ Stanford Court San Francisco, $188 a night, $2,261 for 12 nights · 5★ Taj Campton Place, $357 a night, $4,280 for 12 nights
• Hotels in San Francisco for these nights (Apr 27 – May 10, 2027 · 13 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $144 a night, $1,867 for 13 nights · 4★ Stanford Court San Francisco, $188 a night, $2,447 for 13 nights · 5★ Taj Campton Place, $353 a night, $4,590 for 13 nights
• Hotels in San Francisco for these nights (Apr 27 – May 11, 2027 · 14 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $144 a night, $2,014 for 14 nights · 4★ Stanford Court San Francisco, $198 a night, $2,770 for 14 nights · 5★ Taj Campton Place, $362 a night, $5,064 for 14 nights

All hotels in San Francisco

Route overview: Tampa to San Francisco (SFO) flight deals

2027-04-27 · one way · Axel-exclusive $215

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.

2027-04-27 · one way · Axel-exclusive $255

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.

2027-04-27 → 2027-04-28 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-28 06:10:00 → TPA 2027-04-28 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-28 06:10:00 → DEN 2027-04-28 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-28 10:50:00 → TPA 2027-04-28 16:15:00.

2027-04-27 → 2027-04-28 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA448: SFO 2027-04-28 23:15:00 → TPA 2027-04-29 07:24:00; nonstop; 309 minutes. Local airport times.

2027-04-27 → 2027-04-29 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-04-29 14:00:00 → TPA 2027-04-30 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-04-29 14:00:00 → DAL 2027-04-29 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-04-29 20:50:00 → TPA 2027-04-30 00:10:00.

2027-04-27 → 2027-04-29 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-04-29 07:15:00 → TPA 2027-04-29 15:19:00; nonstop; 304 minutes. Local airport times.

2027-04-27 → 2027-04-30 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN2989 / WN4206: SFO 2027-04-30 13:05:00 → TPA 2027-04-30 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
  • WN2989: SFO 2027-04-30 13:05:00 → STL 2027-04-30 18:55:00; layover at STL: 60 minutes.
  • WN4206: STL 2027-04-30 19:55:00 → TPA 2027-04-30 23:15:00.

2027-04-27 → 2027-04-30 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1112: SFO 2027-04-30 23:59:00 → TPA 2027-05-01 08:05:00; nonstop; 306 minutes. Local airport times.

2027-04-27 → 2027-05-01 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-01 06:10:00 → TPA 2027-05-01 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-01 06:10:00 → DEN 2027-05-01 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-01 10:50:00 → TPA 2027-05-01 16:15:00.

2027-04-27 → 2027-05-01 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1651: SFO 2027-05-01 08:15:00 → TPA 2027-05-01 16:21:00; nonstop; 306 minutes. Local airport times.

2027-04-27 → 2027-05-03 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-05-03 14:00:00 → TPA 2027-05-04 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-05-03 14:00:00 → DAL 2027-05-03 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-05-03 20:50:00 → TPA 2027-05-04 00:10:00.

2027-04-27 → 2027-05-03 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-05-03 07:15:00 → TPA 2027-05-03 15:19:00; nonstop; 304 minutes. Local airport times.

2027-04-27 → 2027-05-04 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-04 06:10:00 → TPA 2027-05-04 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-04 06:10:00 → DEN 2027-05-04 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-04 10:50:00 → TPA 2027-05-04 16:15:00.

2027-04-27 → 2027-05-04 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1885: SFO 2027-05-04 22:55:00 → TPA 2027-05-05 06:52:00; nonstop; 297 minutes. Local airport times.

2027-04-27 → 2027-05-05 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-05 06:10:00 → TPA 2027-05-05 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-05 06:10:00 → DEN 2027-05-05 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-05 10:50:00 → TPA 2027-05-05 16:15:00.

2027-04-27 → 2027-05-05 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA448: SFO 2027-05-05 23:15:00 → TPA 2027-05-06 07:24:00; nonstop; 309 minutes. Local airport times.

2027-04-27 → 2027-05-07 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN2989 / WN4206: SFO 2027-05-07 13:05:00 → TPA 2027-05-07 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
  • WN2989: SFO 2027-05-07 13:05:00 → STL 2027-05-07 18:55:00; layover at STL: 60 minutes.
  • WN4206: STL 2027-05-07 19:55:00 → TPA 2027-05-07 23:15:00.

2027-04-27 → 2027-05-07 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1112: SFO 2027-05-07 23:59:00 → TPA 2027-05-08 08:05:00; nonstop; 306 minutes. Local airport times.

2027-04-27 → 2027-05-08 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-08 06:10:00 → TPA 2027-05-08 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-08 06:10:00 → DEN 2027-05-08 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-08 10:50:00 → TPA 2027-05-08 16:15:00.

2027-04-27 → 2027-05-08 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1651: SFO 2027-05-08 08:15:00 → TPA 2027-05-08 16:21:00; nonstop; 306 minutes. Local airport times.

2027-04-27 → 2027-05-09 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-09 06:10:00 → TPA 2027-05-09 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-09 06:10:00 → DEN 2027-05-09 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-09 10:50:00 → TPA 2027-05-09 16:15:00.

2027-04-27 → 2027-05-09 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1651: SFO 2027-05-09 07:25:00 → TPA 2027-05-09 15:31:00; nonstop; 306 minutes. Local airport times.

2027-04-27 → 2027-05-11 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-27 07:10:00 → SFO 2027-04-27 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-27 07:10:00 → PHX 2027-04-27 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-27 10:10:00 → SFO 2027-04-27 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-05-11 06:10:00 → TPA 2027-05-11 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-05-11 06:10:00 → DEN 2027-05-11 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-05-11 10:50:00 → TPA 2027-05-11 16:15:00.

2027-04-27 → 2027-05-11 · Axel-exclusive $470

• United Airlines UA1986: TPA 2027-04-27 06:00:00 → SFO 2027-04-27 09:03:00; nonstop; 363 minutes. Local airport times.
• United Airlines UA1885: SFO 2027-05-11 22:55:00 → TPA 2027-05-12 06:52:00; nonstop; 297 minutes. Local airport times.

Explore this route

• All dates for this route
• Apr 26, 2027 · Return options
• Apr 28, 2027 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Tampa (TPA) to San Francisco (SFO) · Apr 27, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Tampa to San Francisco (SFO) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

Feedback (optional): Missing info · Axel issue