Tampa (TPA) to San Francisco (SFO), Apr 12, 2027: round trips from $400, one way from $215

Tampa (TPA) to San Francisco (SFO), Apr 12, 2027: round trips from $400, one way from $215 on Axel, checked Nov 14, 2026. Lowest published fares: $400 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Apr 12–13, 2027; $215 one way, Axel-exclusive, Southwest Airlines, 1 stop, Apr 12, 2027; 1 adult, economy, checked Nov 14, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Apr 12–13, 2027 · 1 night · 2 adults, 1 room): 3★ The Pickwick Hotel, $122 a night · 4★ BEI Hotel San Francisco, $159 a night · 5★ Taj Campton Place, $327 a night
• Hotels in San Francisco for these nights (Apr 12–14, 2027 · 2 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $102 a night, $204 for 2 nights · 4★ BEI Hotel San Francisco, $154 a night, $308 for 2 nights · 5★ Taj Campton Place, $342 a night, $684 for 2 nights
• Hotels in San Francisco for these nights (Apr 12–15, 2027 · 3 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $108 a night, $324 for 3 nights · 4★ BEI Hotel San Francisco, $155 a night, $464 for 3 nights · 5★ Taj Campton Place, $343 a night, $1,028 for 3 nights
• Hotels in San Francisco for these nights (Apr 12–16, 2027 · 4 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $112 a night, $446 for 4 nights · 4★ BEI Hotel San Francisco, $156 a night, $622 for 4 nights · 5★ Taj Campton Place, $345 a night, $1,381 for 4 nights
• Hotels in San Francisco for these nights (Apr 12–17, 2027 · 5 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $122 a night, $609 for 5 nights · 4★ BEI Hotel San Francisco, $156 a night, $778 for 5 nights · 5★ Taj Campton Place, $343 a night, $1,714 for 5 nights
• Hotels in San Francisco for these nights (Apr 12–18, 2027 · 6 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $128 a night, $766 for 6 nights · 4★ BEI Hotel San Francisco, $155 a night, $930 for 6 nights · 5★ Taj Campton Place, $343 a night, $2,058 for 6 nights
• Hotels in San Francisco for these nights (Apr 12–19, 2027 · 7 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $127 a night, $886 for 7 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,086 for 7 nights · 5★ Taj Campton Place, $343 a night, $2,399 for 7 nights
• Hotels in San Francisco for these nights (Apr 12–20, 2027 · 8 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $126 a night, $1,008 for 8 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,239 for 8 nights · 5★ Taj Campton Place, $342 a night, $2,738 for 8 nights
• Hotels in San Francisco for these nights (Apr 12–21, 2027 · 9 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $140 a night, $1,261 for 9 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,396 for 9 nights · 5★ Taj Campton Place, $343 a night, $3,085 for 9 nights
• Hotels in San Francisco for these nights (Apr 12–22, 2027 · 10 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $150 a night, $1,504 for 10 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,552 for 10 nights · 5★ Taj Campton Place, $345 a night, $3,449 for 10 nights
• Hotels in San Francisco for these nights (Apr 12–23, 2027 · 11 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $148 a night, $1,624 for 11 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,708 for 11 nights · 5★ Taj Campton Place, $348 a night, $3,826 for 11 nights
• Hotels in San Francisco for these nights (Apr 12–24, 2027 · 12 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $148 a night, $1,781 for 12 nights · 4★ BEI Hotel San Francisco, $155 a night, $1,864 for 12 nights · 5★ Taj Campton Place, $347 a night, $4,165 for 12 nights
• Hotels in San Francisco for these nights (Apr 12–25, 2027 · 13 nights · 2 adults, 1 room): 3★ Tilden Hotel, $148 a night, $1,926 for 13 nights · 4★ BEI Hotel San Francisco, $156 a night, $2,023 for 13 nights · 5★ Taj Campton Place, $346 a night, $4,498 for 13 nights
• Hotels in San Francisco for these nights (Apr 12–26, 2027 · 14 nights · 2 adults, 1 room): 3★ Tilden Hotel, $146 a night, $2,046 for 14 nights · 4★ BEI Hotel San Francisco, $156 a night, $2,182 for 14 nights · 5★ Taj Campton Place, $345 a night, $4,832 for 14 nights

All hotels in San Francisco

Route overview: Tampa to San Francisco (SFO) flight deals

2027-04-12 · one way · Axel-exclusive $215

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.

2027-04-12 · one way · Axel-exclusive $255

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.

2027-04-12 → 2027-04-13 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-13 06:10:00 → TPA 2027-04-13 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-13 06:10:00 → DEN 2027-04-13 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-13 10:50:00 → TPA 2027-04-13 16:15:00.

2027-04-12 → 2027-04-13 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1885: SFO 2027-04-13 22:55:00 → TPA 2027-04-14 06:52:00; nonstop; 297 minutes. Local airport times.

2027-04-12 → 2027-04-14 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-14 06:10:00 → TPA 2027-04-14 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-14 06:10:00 → DEN 2027-04-14 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-14 10:50:00 → TPA 2027-04-14 16:15:00.

2027-04-12 → 2027-04-14 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA448: SFO 2027-04-14 23:15:00 → TPA 2027-04-15 07:24:00; nonstop; 309 minutes. Local airport times.

2027-04-12 → 2027-04-15 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-04-15 14:00:00 → TPA 2027-04-16 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-04-15 14:00:00 → DAL 2027-04-15 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-04-15 20:50:00 → TPA 2027-04-16 00:10:00.

2027-04-12 → 2027-04-15 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-04-15 07:15:00 → TPA 2027-04-15 15:19:00; nonstop; 304 minutes. Local airport times.

2027-04-12 → 2027-04-16 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN2989 / WN4206: SFO 2027-04-16 13:05:00 → TPA 2027-04-16 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
  • WN2989: SFO 2027-04-16 13:05:00 → STL 2027-04-16 18:55:00; layover at STL: 60 minutes.
  • WN4206: STL 2027-04-16 19:55:00 → TPA 2027-04-16 23:15:00.

2027-04-12 → 2027-04-16 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1112: SFO 2027-04-16 23:59:00 → TPA 2027-04-17 08:05:00; nonstop; 306 minutes. Local airport times.

2027-04-12 → 2027-04-18 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-18 06:10:00 → TPA 2027-04-18 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-18 06:10:00 → DEN 2027-04-18 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-18 10:50:00 → TPA 2027-04-18 16:15:00.

2027-04-12 → 2027-04-18 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1651: SFO 2027-04-18 07:25:00 → TPA 2027-04-18 15:31:00; nonstop; 306 minutes. Local airport times.

2027-04-12 → 2027-04-19 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-04-19 14:00:00 → TPA 2027-04-20 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-04-19 14:00:00 → DAL 2027-04-19 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-04-19 20:50:00 → TPA 2027-04-20 00:10:00.

2027-04-12 → 2027-04-19 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-04-19 07:15:00 → TPA 2027-04-19 15:19:00; nonstop; 304 minutes. Local airport times.

2027-04-12 → 2027-04-20 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-20 06:10:00 → TPA 2027-04-20 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-20 06:10:00 → DEN 2027-04-20 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-20 10:50:00 → TPA 2027-04-20 16:15:00.

2027-04-12 → 2027-04-20 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1885: SFO 2027-04-20 22:55:00 → TPA 2027-04-21 06:52:00; nonstop; 297 minutes. Local airport times.

2027-04-12 → 2027-04-22 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-04-22 14:00:00 → TPA 2027-04-23 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-04-22 14:00:00 → DAL 2027-04-22 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-04-22 20:50:00 → TPA 2027-04-23 00:10:00.

2027-04-12 → 2027-04-22 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-04-22 07:15:00 → TPA 2027-04-22 15:19:00; nonstop; 304 minutes. Local airport times.

2027-04-12 → 2027-04-23 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN2989 / WN4206: SFO 2027-04-23 13:05:00 → TPA 2027-04-23 23:15:00; 1 stop(s) via STL; 430 minutes. Local airport times.
  • WN2989: SFO 2027-04-23 13:05:00 → STL 2027-04-23 18:55:00; layover at STL: 60 minutes.
  • WN4206: STL 2027-04-23 19:55:00 → TPA 2027-04-23 23:15:00.

2027-04-12 → 2027-04-23 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1112: SFO 2027-04-23 23:59:00 → TPA 2027-04-24 08:05:00; nonstop; 306 minutes. Local airport times.

2027-04-12 → 2027-04-24 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN4578 / WN489: SFO 2027-04-24 06:10:00 → TPA 2027-04-24 16:15:00; 1 stop(s) via DEN; 425 minutes. Local airport times.
  • WN4578: SFO 2027-04-24 06:10:00 → DEN 2027-04-24 09:45:00; layover at DEN: 65 minutes.
  • WN489: DEN 2027-04-24 10:50:00 → TPA 2027-04-24 16:15:00.

2027-04-12 → 2027-04-24 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA1651: SFO 2027-04-24 08:15:00 → TPA 2027-04-24 16:21:00; nonstop; 306 minutes. Local airport times.

2027-04-12 → 2027-04-26 · Axel-exclusive $400

• Southwest Airlines WN4274 / WN327: TPA 2027-04-12 07:10:00 → SFO 2027-04-12 12:20:00; 1 stop(s) via PHX; 490 minutes. Local airport times.
  • WN4274: TPA 2027-04-12 07:10:00 → PHX 2027-04-12 09:00:00; layover at PHX: 70 minutes.
  • WN327: PHX 2027-04-12 10:10:00 → SFO 2027-04-12 12:20:00.
• Southwest Airlines WN1982 / WN1434: SFO 2027-04-26 14:00:00 → TPA 2027-04-27 00:10:00; 1 stop(s) via DAL; 430 minutes. Local airport times.
  • WN1982: SFO 2027-04-26 14:00:00 → DAL 2027-04-26 19:30:00; layover at DAL: 80 minutes.
  • WN1434: DAL 2027-04-26 20:50:00 → TPA 2027-04-27 00:10:00.

2027-04-12 → 2027-04-26 · Axel-exclusive $470

• United Airlines UA270: TPA 2027-04-12 08:00:00 → SFO 2027-04-12 11:01:00; nonstop; 361 minutes. Local airport times.
• United Airlines UA2799: SFO 2027-04-26 07:15:00 → TPA 2027-04-26 15:19:00; nonstop; 304 minutes. Local airport times.

Explore this route

• All dates for this route
• Apr 11, 2027 · Return options
• Apr 13, 2027 · Return options
• Hotels in San Francisco with Axel

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• This page: Tampa (TPA) to San Francisco (SFO) · Apr 12, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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