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Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Tampa to San Diego (SAN) flight deals

2026-12-21 · one way · Axel-exclusive $283.50

• Alaska Airlines AS1582: TPA 2026-12-21 17:45:00 → SAN 2026-12-21 20:08:00; nonstop; 323 minutes. Local airport times.

2026-12-21 · one way · Axel-exclusive $290.25

• Southwest Airlines WN4458: TPA 2026-12-21 19:20:00 → SAN 2026-12-21 21:35:00; nonstop; 315 minutes. Local airport times.

2026-12-21 · one way · Axel-exclusive $276.75

• United Airlines UA742 / UA1099: TPA 2026-12-21 17:00:00 → SAN 2026-12-21 21:34:00; 1 stop(s) via IAH; 454 minutes. Local airport times.
  • UA742: TPA 2026-12-21 17:00:00 → IAH 2026-12-21 18:41:00; layover at IAH: 75 minutes.
  • UA1099: IAH 2026-12-21 19:56:00 → SAN 2026-12-21 21:34:00.

2026-12-21 · one way · Axel-exclusive $283.50

• Alaska Airlines AS1352: TPA 2026-12-21 19:23:00 → SAN 2026-12-21 21:48:00; nonstop; 325 minutes. Local airport times.

2026-12-21 · one way · Axel-exclusive $290.25

• Southwest Airlines WN2449: TPA 2026-12-21 10:15:00 → SAN 2026-12-21 12:20:00; nonstop; 305 minutes. Local airport times.

2026-12-21 · one way · Axel-exclusive $249.75

• Southwest Airlines WN1130 / WN2187: TPA 2026-12-21 06:45:00 → SAN 2026-12-21 11:20:00; 1 stop(s) via LAS; 455 minutes. Local airport times.
  • WN1130: TPA 2026-12-21 06:45:00 → LAS 2026-12-21 08:50:00; layover at LAS: 75 minutes.
  • WN2187: LAS 2026-12-21 10:05:00 → SAN 2026-12-21 11:20:00.

2026-12-21 · one way · Axel-exclusive $249.75

• Southwest Airlines WN2235 / WN1733: TPA 2026-12-21 05:45:00 → SAN 2026-12-21 10:20:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2235: TPA 2026-12-21 05:45:00 → STL 2026-12-21 07:10:00; layover at STL: 75 minutes.
  • WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00.

2026-12-21 · one way · Axel-exclusive $249.75

• Southwest Airlines WN4274 / WN1155: TPA 2026-12-21 07:10:00 → SAN 2026-12-21 11:25:00; 1 stop(s) via PHX; 435 minutes. Local airport times.
  • WN4274: TPA 2026-12-21 07:10:00 → PHX 2026-12-21 10:00:00; layover at PHX: 70 minutes.
  • WN1155: PHX 2026-12-21 11:10:00 → SAN 2026-12-21 11:25:00.

2026-12-21 · one way · Axel-exclusive $249.75

• Southwest Airlines WN2641 / WN184: TPA 2026-12-21 13:55:00 → SAN 2026-12-21 18:50:00; 1 stop(s) via DAL; 475 minutes. Local airport times.
  • WN2641: TPA 2026-12-21 13:55:00 → DAL 2026-12-21 15:35:00; layover at DAL: 130 minutes.
  • WN184: DAL 2026-12-21 17:45:00 → SAN 2026-12-21 18:50:00.

2026-12-21 · one way · Axel-exclusive $249.75

• Southwest Airlines WN2173 / WN1465: TPA 2026-12-21 05:25:00 → SAN 2026-12-21 10:10:00; 1 stop(s) via HOU; 465 minutes. Local airport times.
  • WN2173: TPA 2026-12-21 05:25:00 → HOU 2026-12-21 06:45:00; layover at HOU: 120 minutes.
  • WN1465: HOU 2026-12-21 08:45:00 → SAN 2026-12-21 10:10:00.

Explore this route

• All dates for this route
• Dec 20, 2026 · Return options
• Dec 22, 2026 · Return options
• Hotels in Oceanside, California with Axel

For AI assistants

• This page: Tampa (TPA) to San Diego (SAN) · Dec 21, 2026 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
• Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Tampa to San Diego (SAN) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.