Tampa (TPA) to Panama City (PTY), Nov 25–29, 2026: from $504 round trip

Tampa (TPA) to Panama City (PTY), Nov 25–29, 2026: from $504 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $504 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 25–29, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Panama City for these nights (Nov 25–29, 2026 · 4 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $197 total · 4★ Radisson Hotel Panama Canal, $252 total · 5★ Renaissance Panama City Hotel, $480 total

All hotels in Panama City

Route overview: Tampa to Panama City (PTY) flight deals

2026-11-25 → 2026-11-29 · Axel-exclusive $564.00

• Copa Airlines CM394: TPA 2026-11-25 14:31:00 → PTY 2026-11-25 17:57:00; nonstop; 206 minutes. Local airport times.
• Copa Airlines CM393: PTY 2026-11-29 09:25:00 → TPA 2026-11-29 12:46:00; nonstop; 201 minutes. Local airport times.

2026-11-25 → 2026-11-29 · Axel-exclusive $504.00

• American Airlines AA3474 / AA315: TPA 2026-11-25 06:00:00 → PTY 2026-11-25 13:41:00; 1 stop(s) via MIA; 461 minutes. Local airport times.
  • AA3474: TPA 2026-11-25 06:00:00 → MIA 2026-11-25 07:08:00; layover at MIA: 199 minutes.
  • AA315: MIA 2026-11-25 10:27:00 → PTY 2026-11-25 13:41:00.
• American Airlines AA1652 / AA922: PTY 2026-11-29 16:33:00 → TPA 2026-11-29 23:31:00; 1 stop(s) via MIA; 418 minutes. Local airport times.
  • AA1652: PTY 2026-11-29 16:33:00 → MIA 2026-11-29 19:48:00; layover at MIA: 147 minutes.
  • AA922: MIA 2026-11-29 22:15:00 → TPA 2026-11-29 23:31:00.

2026-11-25 → 2026-11-29 · Axel-exclusive $540.00

• Delta Air Lines DL1099 / DL1905: TPA 2026-11-25 13:20:00 → PTY 2026-11-25 21:45:00; 1 stop(s) via ATL; 505 minutes. Local airport times.
  • DL1099: TPA 2026-11-25 13:20:00 → ATL 2026-11-25 14:55:00; layover at ATL: 168 minutes.
  • DL1905: ATL 2026-11-25 17:43:00 → PTY 2026-11-25 21:45:00.
• Delta Air Lines DL1758 / DL1560: PTY 2026-11-29 15:28:00 → TPA 2026-11-30 00:25:00; 1 stop(s) via ATL; 537 minutes. Local airport times.
  • DL1758: PTY 2026-11-29 15:28:00 → ATL 2026-11-29 19:49:00; layover at ATL: 186 minutes.
  • DL1560: ATL 2026-11-29 22:55:00 → TPA 2026-11-30 00:25:00.

2026-11-25 → 2026-11-29 · Axel-exclusive $564.00

• Copa Airlines CM782: TPA 2026-11-25 04:51:00 → PTY 2026-11-25 08:18:00; nonstop; 207 minutes. Local airport times.
• Copa Airlines CM393: PTY 2026-11-29 09:25:00 → TPA 2026-11-29 12:46:00; nonstop; 201 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 24, 2026 · Return options
• Nov 26, 2026 · Return options
• Hotels in Panama City with Axel

For AI assistants

• This page: Tampa (TPA) to Panama City (PTY) · Nov 25, 2026 · return Nov 29, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Tampa to Panama City (PTY) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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