Saint Louis (STL) to Fort Myers (RSW), Mar 21, 2027: from $218 one way

Saint Louis (STL) to Fort Myers (RSW), Mar 21, 2027: from $218 one way on Axel, checked Nov 13, 2026. Lowest published fare: $218 one way, Axel-exclusive, Southwest Airlines, 1 stop, Mar 21, 2027, 1 adult, economy, checked Nov 13, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Saint Louis to Fort Myers (RSW) flight deals

2027-03-21 · one way · Axel-exclusive $238

• Southwest Airlines WN4196: STL 2027-03-21 18:20:00 → RSW 2027-03-21 21:50:00; nonstop; 150 minutes. Local airport times.

2027-03-21 · one way · Axel-exclusive $251

• United Airlines UA4406 / UA2660: STL 2027-03-21 08:30:00 → RSW 2027-03-21 15:27:00; 1 stop(s) via IAD; 357 minutes. Local airport times.
  • UA4406: STL 2027-03-21 08:30:00 → IAD 2027-03-21 11:35:00; layover at IAD: 60 minutes.
  • UA2660: IAD 2027-03-21 12:35:00 → RSW 2027-03-21 15:27:00.

2027-03-21 · one way · Axel-exclusive $264

• Delta Air Lines DL1393 / DL1217: STL 2027-03-21 19:18:00 → RSW 2027-03-22 00:40:00; 1 stop(s) via ATL; 262 minutes. Local airport times.
  • DL1393: STL 2027-03-21 19:18:00 → ATL 2027-03-21 21:59:00; layover at ATL: 60 minutes.
  • DL1217: ATL 2027-03-21 22:59:00 → RSW 2027-03-22 00:40:00.

2027-03-21 · one way · Axel-exclusive $238

• Southwest Airlines WN4195: STL 2027-03-21 16:10:00 → RSW 2027-03-21 19:35:00; nonstop; 145 minutes. Local airport times.

2027-03-21 · one way · Axel-exclusive $218

• Southwest Airlines WN665 / WN3014: STL 2027-03-21 10:35:00 → RSW 2027-03-21 15:55:00; 1 stop(s) via BNA; 260 minutes. Local airport times.
  • WN665: STL 2027-03-21 10:35:00 → BNA 2027-03-21 11:40:00; layover at BNA: 75 minutes.
  • WN3014: BNA 2027-03-21 12:55:00 → RSW 2027-03-21 15:55:00.

2027-03-21 · one way · Axel-exclusive $218

• Southwest Airlines WN4170 / WN2937: STL 2027-03-21 16:20:00 → RSW 2027-03-21 21:55:00; 1 stop(s) via MCO; 275 minutes. Local airport times.
  • WN4170: STL 2027-03-21 16:20:00 → MCO 2027-03-21 19:40:00; layover at MCO: 65 minutes.
  • WN2937: MCO 2027-03-21 20:45:00 → RSW 2027-03-21 21:55:00.

2027-03-21 · one way · Axel-exclusive $218

• Southwest Airlines WN287 / WN2097: STL 2027-03-21 10:55:00 → RSW 2027-03-21 17:00:00; 1 stop(s) via MDW; 305 minutes. Local airport times.
  • WN287: STL 2027-03-21 10:55:00 → MDW 2027-03-21 12:05:00; layover at MDW: 70 minutes.
  • WN2097: MDW 2027-03-21 13:15:00 → RSW 2027-03-21 17:00:00.

2027-03-21 · one way · Axel-exclusive $218

• Southwest Airlines WN4372 / WN1377: STL 2027-03-21 12:40:00 → RSW 2027-03-21 19:00:00; 1 stop(s) via MCI; 320 minutes. Local airport times.
  • WN4372: STL 2027-03-21 12:40:00 → MCI 2027-03-21 13:45:00; layover at MCI: 90 minutes.
  • WN1377: MCI 2027-03-21 15:15:00 → RSW 2027-03-21 19:00:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Mar 20, 2027 · Return options
• Mar 22, 2027 · Return options
• Hotels in Fort Myers with Axel

For AI assistants

• This page: Saint Louis (STL) to Fort Myers (RSW) · Mar 21, 2027 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date.
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