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Saint Louis → Rome

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STL → FCO1 adulteconomy

18 flight options · 4 airlines

Round-trip flights

Fri, Nov 20 – Mon, Nov 23

Air Canada
4:05 pmSTL
11h 50m
YYZ · 1h 35m
10:55 am+1FCO
Lufthansa
7:05 amFCO
13h 40m
FRA · 1h 45m
1:45 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
12:49 pmSTL
13h 11m
PHL · 2h 38m
9:00 am+1FCO
Lufthansa
7:05 amFCO
13h 40m
FRA · 1h 45m
1:45 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
10:50 amSTL
13h 55m
ORD · 3h 15m
7:45 am+1FCO
United Airlines
9:45 amFCO
14h 28m
ORD · 2h 25m
5:13 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
2:17 pmSTL
12h 18m
DTW · 1h 52m
9:35 am+1FCO
Delta Air Lines
10:00 amFCO
14h 20m
DTW · 2h 3m
5:20 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Air Canada
4:05 pmSTL
11h 50m
YYZ · 1h 35m
10:55 am+1FCO
Lufthansa
7:05 amFCO
13h 40m
FRA · 1h 45m
1:45 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
11:05 amSTL
13h 50m
EWR · 3h 9m
7:55 am+1FCO
United Airlines
9:45 amFCO
14h 28m
ORD · 2h 25m
5:13 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
2:31 pmSTL
13h 49m
ATL · 2h 55m
11:20 am+1FCO
Delta Air Lines
10:00 amFCO
14h 20m
DTW · 2h 3m
5:20 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

American Airlines
12:49 pmSTL
13h 11m
PHL · 2h 38m
9:00 am+1FCO
Lufthansa
7:05 amFCO
13h 40m
FRA · 1h 45m
1:45 pmSTL

Round-trip total · 1 adult · Taxes included

Show 4 more flights

Fri, Nov 27 – Fri, Dec 4

United Airlines
11:05 amSTL
13h 50m
EWR · 3h 9m
7:55 am+1FCO
United Airlines
9:45 amFCO
14h 28m
ORD · 2h 25m
5:13 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
10:50 amSTL
13h 55m
ORD · 3h 15m
7:45 am+1FCO
United Airlines
9:45 amFCO
14h 28m
ORD · 2h 25m
5:13 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
2:31 pmSTL
13h 49m
ATL · 2h 55m
11:20 am+1FCO
Delta Air Lines
10:00 amFCO
14h 20m
DTW · 2h 3m
5:20 pmSTL

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
2:17 pmSTL
12h 18m
DTW · 1h 52m
9:35 am+1FCO
Delta Air Lines
10:00 amFCO
14h 20m
DTW · 2h 3m
5:20 pmSTL

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Air Canada
4:05 pmSTL
11h 50m
YYZ · 1h 35m
10:55 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

American Airlines
12:49 pmSTL
13h 11m
PHL · 2h 38m
9:00 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
11:05 amSTL
13h 50m
EWR · 3h 9m
7:55 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
2:17 pmSTL
12h 18m
DTW · 1h 52m
9:35 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
10:50 amSTL
13h 55m
ORD · 3h 15m
7:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
2:31 pmSTL
13h 49m
ATL · 2h 55m
11:20 am+1FCO

One-way total · 1 adult · Taxes included

Make this trip yours

STL ⇄ FCO

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Air Canada emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one wayAir CanadaAC8890 + AC890$570.002026-10-29T01:28:30Z
2026-11-20 · one wayAmerican AirlinesAA5105 + AA718$608.002026-10-29T01:28:30Z
2026-11-20 · one wayUnited AirlinesUA2612 + UA40$617.502026-10-29T01:28:30Z
2026-11-20 · one wayDelta Air LinesDL1371 + DL206$636.502026-10-29T01:28:30Z
2026-11-20 → 2026-11-23Air Canada / LufthansaAC8890 + AC890 / LH241 + LH448$902.502026-10-29T01:28:30Z
2026-11-20 → 2026-11-23American Airlines / LufthansaAA5105 + AA718 / LH241 + LH448$926.252026-10-29T01:28:30Z
2026-11-20 → 2026-11-23United AirlinesUA4517 + UA970 / UA971 + UA4474$931.002026-10-29T01:28:30Z
2026-11-20 → 2026-11-23Delta Air LinesDL1371 + DL206 / DL207 + DL2822$950.002026-10-29T01:28:30Z
2026-11-27 → 2026-12-04Air Canada / LufthansaAC8890 + AC890 / LH241 + LH448$927.252026-10-29T01:28:30Z
2026-11-20 · one wayUnited AirlinesUA4517 + UA970$617.502026-10-29T01:28:30Z
2026-11-20 · one wayDelta Air LinesDL1102 + DL66$636.502026-10-29T01:28:30Z
2026-11-20 → 2026-11-23United AirlinesUA2612 + UA40 / UA971 + UA4474$931.002026-10-29T01:28:30Z
2026-11-20 → 2026-11-23Delta Air LinesDL1102 + DL66 / DL207 + DL2822$950.002026-10-29T01:28:30Z
2026-11-27 → 2026-12-04American Airlines / LufthansaAA5105 + AA718 / LH241 + LH448$951.002026-10-29T01:28:30Z
2026-11-27 → 2026-12-04United AirlinesUA2612 + UA40 / UA971 + UA4474$955.502026-10-29T01:28:30Z
2026-11-27 → 2026-12-04United AirlinesUA4517 + UA970 / UA971 + UA4474$955.502026-10-29T01:28:30Z
2026-11-27 → 2026-12-04Delta Air LinesDL1102 + DL66 / DL207 + DL2822$975.002026-10-29T01:28:30Z
2026-11-27 → 2026-12-04Delta Air LinesDL1371 + DL206 / DL207 + DL2822$975.002026-10-29T01:28:30Z

2026-11-20 · one way · $570.00

  • Air Canada AC8890 / AC890: STL 2026-11-20 16:05:00 → FCO 2026-11-21 10:55:00; 1 stop(s) via YYZ; 710 minutes. Local airport times.
    • AC8890: STL 2026-11-20 16:05:00 → YYZ 2026-11-20 19:05:00; layover at YYZ: 95 minutes.
    • AC890: YYZ 2026-11-20 20:40:00 → FCO 2026-11-21 10:55:00.

2026-11-20 · one way · $608.00

  • American Airlines AA5105 / AA718: STL 2026-11-20 12:49:00 → FCO 2026-11-21 09:00:00; 1 stop(s) via PHL; 791 minutes. Local airport times.
    • AA5105: STL 2026-11-20 12:49:00 → PHL 2026-11-20 16:02:00; layover at PHL: 158 minutes.
    • AA718: PHL 2026-11-20 18:40:00 → FCO 2026-11-21 09:00:00.

2026-11-20 · one way · $617.50

  • United Airlines UA2612 / UA40: STL 2026-11-20 11:05:00 → FCO 2026-11-21 07:55:00; 1 stop(s) via EWR; 830 minutes. Local airport times.
    • UA2612: STL 2026-11-20 11:05:00 → EWR 2026-11-20 14:31:00; layover at EWR: 189 minutes.
    • UA40: EWR 2026-11-20 17:40:00 → FCO 2026-11-21 07:55:00.

2026-11-20 · one way · $636.50

  • Delta Air Lines DL1371 / DL206: STL 2026-11-20 14:17:00 → FCO 2026-11-21 09:35:00; 1 stop(s) via DTW; 738 minutes. Local airport times.
    • DL1371: STL 2026-11-20 14:17:00 → DTW 2026-11-20 16:53:00; layover at DTW: 112 minutes.
    • DL206: DTW 2026-11-20 18:45:00 → FCO 2026-11-21 09:35:00.

2026-11-20 → 2026-11-23 · $902.50

  • Air Canada AC8890 / AC890: STL 2026-11-20 16:05:00 → FCO 2026-11-21 10:55:00; 1 stop(s) via YYZ; 710 minutes. Local airport times.
    • AC8890: STL 2026-11-20 16:05:00 → YYZ 2026-11-20 19:05:00; layover at YYZ: 95 minutes.
    • AC890: YYZ 2026-11-20 20:40:00 → FCO 2026-11-21 10:55:00.
  • Lufthansa LH241 / LH448: FCO 2026-11-23 07:05:00 → STL 2026-11-23 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
    • LH241: FCO 2026-11-23 07:05:00 → FRA 2026-11-23 09:00:00; layover at FRA: 105 minutes.
    • LH448: FRA 2026-11-23 10:45:00 → STL 2026-11-23 13:45:00.

2026-11-20 → 2026-11-23 · $926.25

  • American Airlines AA5105 / AA718: STL 2026-11-20 12:49:00 → FCO 2026-11-21 09:00:00; 1 stop(s) via PHL; 791 minutes. Local airport times.
    • AA5105: STL 2026-11-20 12:49:00 → PHL 2026-11-20 16:02:00; layover at PHL: 158 minutes.
    • AA718: PHL 2026-11-20 18:40:00 → FCO 2026-11-21 09:00:00.
  • Lufthansa LH241 / LH448: FCO 2026-11-23 07:05:00 → STL 2026-11-23 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
    • LH241: FCO 2026-11-23 07:05:00 → FRA 2026-11-23 09:00:00; layover at FRA: 105 minutes.
    • LH448: FRA 2026-11-23 10:45:00 → STL 2026-11-23 13:45:00.

2026-11-20 → 2026-11-23 · $931.00

  • United Airlines UA4517 / UA970: STL 2026-11-20 10:50:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 835 minutes. Local airport times.
    • UA4517: STL 2026-11-20 10:50:00 → ORD 2026-11-20 12:25:00; layover at ORD: 195 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.
  • United Airlines UA971 / UA4474: FCO 2026-11-23 09:45:00 → STL 2026-11-23 17:13:00; 1 stop(s) via ORD; 868 minutes. Local airport times.
    • UA971: FCO 2026-11-23 09:45:00 → ORD 2026-11-23 13:10:00; layover at ORD: 145 minutes.
    • UA4474: ORD 2026-11-23 15:35:00 → STL 2026-11-23 17:13:00.

2026-11-20 → 2026-11-23 · $950.00

  • Delta Air Lines DL1371 / DL206: STL 2026-11-20 14:17:00 → FCO 2026-11-21 09:35:00; 1 stop(s) via DTW; 738 minutes. Local airport times.
    • DL1371: STL 2026-11-20 14:17:00 → DTW 2026-11-20 16:53:00; layover at DTW: 112 minutes.
    • DL206: DTW 2026-11-20 18:45:00 → FCO 2026-11-21 09:35:00.
  • Delta Air Lines DL207 / DL2822: FCO 2026-11-23 10:00:00 → STL 2026-11-23 17:20:00; 1 stop(s) via DTW; 860 minutes. Local airport times.
    • DL207: FCO 2026-11-23 10:00:00 → DTW 2026-11-23 14:30:00; layover at DTW: 123 minutes.
    • DL2822: DTW 2026-11-23 16:33:00 → STL 2026-11-23 17:20:00.

2026-11-27 → 2026-12-04 · $927.25

  • Air Canada AC8890 / AC890: STL 2026-11-27 16:05:00 → FCO 2026-11-28 10:55:00; 1 stop(s) via YYZ; 710 minutes. Local airport times.
    • AC8890: STL 2026-11-27 16:05:00 → YYZ 2026-11-27 19:05:00; layover at YYZ: 95 minutes.
    • AC890: YYZ 2026-11-27 20:40:00 → FCO 2026-11-28 10:55:00.
  • Lufthansa LH241 / LH448: FCO 2026-12-04 07:05:00 → STL 2026-12-04 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
    • LH241: FCO 2026-12-04 07:05:00 → FRA 2026-12-04 09:00:00; layover at FRA: 105 minutes.
    • LH448: FRA 2026-12-04 10:45:00 → STL 2026-12-04 13:45:00.

2026-11-20 · one way · $617.50

  • United Airlines UA4517 / UA970: STL 2026-11-20 10:50:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 835 minutes. Local airport times.
    • UA4517: STL 2026-11-20 10:50:00 → ORD 2026-11-20 12:25:00; layover at ORD: 195 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.

2026-11-20 · one way · $636.50

  • Delta Air Lines DL1102 / DL66: STL 2026-11-20 14:31:00 → FCO 2026-11-21 11:20:00; 1 stop(s) via ATL; 829 minutes. Local airport times.
    • DL1102: STL 2026-11-20 14:31:00 → ATL 2026-11-20 17:05:00; layover at ATL: 175 minutes.
    • DL66: ATL 2026-11-20 20:00:00 → FCO 2026-11-21 11:20:00.

2026-11-20 → 2026-11-23 · $931.00

  • United Airlines UA2612 / UA40: STL 2026-11-20 11:05:00 → FCO 2026-11-21 07:55:00; 1 stop(s) via EWR; 830 minutes. Local airport times.
    • UA2612: STL 2026-11-20 11:05:00 → EWR 2026-11-20 14:31:00; layover at EWR: 189 minutes.
    • UA40: EWR 2026-11-20 17:40:00 → FCO 2026-11-21 07:55:00.
  • United Airlines UA971 / UA4474: FCO 2026-11-23 09:45:00 → STL 2026-11-23 17:13:00; 1 stop(s) via ORD; 868 minutes. Local airport times.
    • UA971: FCO 2026-11-23 09:45:00 → ORD 2026-11-23 13:10:00; layover at ORD: 145 minutes.
    • UA4474: ORD 2026-11-23 15:35:00 → STL 2026-11-23 17:13:00.

2026-11-20 → 2026-11-23 · $950.00

  • Delta Air Lines DL1102 / DL66: STL 2026-11-20 14:31:00 → FCO 2026-11-21 11:20:00; 1 stop(s) via ATL; 829 minutes. Local airport times.
    • DL1102: STL 2026-11-20 14:31:00 → ATL 2026-11-20 17:05:00; layover at ATL: 175 minutes.
    • DL66: ATL 2026-11-20 20:00:00 → FCO 2026-11-21 11:20:00.
  • Delta Air Lines DL207 / DL2822: FCO 2026-11-23 10:00:00 → STL 2026-11-23 17:20:00; 1 stop(s) via DTW; 860 minutes. Local airport times.
    • DL207: FCO 2026-11-23 10:00:00 → DTW 2026-11-23 14:30:00; layover at DTW: 123 minutes.
    • DL2822: DTW 2026-11-23 16:33:00 → STL 2026-11-23 17:20:00.

2026-11-27 → 2026-12-04 · $951.00

  • American Airlines AA5105 / AA718: STL 2026-11-27 12:49:00 → FCO 2026-11-28 09:00:00; 1 stop(s) via PHL; 791 minutes. Local airport times.
    • AA5105: STL 2026-11-27 12:49:00 → PHL 2026-11-27 16:02:00; layover at PHL: 158 minutes.
    • AA718: PHL 2026-11-27 18:40:00 → FCO 2026-11-28 09:00:00.
  • Lufthansa LH241 / LH448: FCO 2026-12-04 07:05:00 → STL 2026-12-04 13:45:00; 1 stop(s) via FRA; 820 minutes. Local airport times.
    • LH241: FCO 2026-12-04 07:05:00 → FRA 2026-12-04 09:00:00; layover at FRA: 105 minutes.
    • LH448: FRA 2026-12-04 10:45:00 → STL 2026-12-04 13:45:00.

2026-11-27 → 2026-12-04 · $955.50

  • United Airlines UA2612 / UA40: STL 2026-11-27 11:05:00 → FCO 2026-11-28 07:55:00; 1 stop(s) via EWR; 830 minutes. Local airport times.
    • UA2612: STL 2026-11-27 11:05:00 → EWR 2026-11-27 14:31:00; layover at EWR: 189 minutes.
    • UA40: EWR 2026-11-27 17:40:00 → FCO 2026-11-28 07:55:00.
  • United Airlines UA971 / UA4474: FCO 2026-12-04 09:45:00 → STL 2026-12-04 17:13:00; 1 stop(s) via ORD; 868 minutes. Local airport times.
    • UA971: FCO 2026-12-04 09:45:00 → ORD 2026-12-04 13:10:00; layover at ORD: 145 minutes.
    • UA4474: ORD 2026-12-04 15:35:00 → STL 2026-12-04 17:13:00.

2026-11-27 → 2026-12-04 · $955.50

  • United Airlines UA4517 / UA970: STL 2026-11-27 10:50:00 → FCO 2026-11-28 07:45:00; 1 stop(s) via ORD; 835 minutes. Local airport times.
    • UA4517: STL 2026-11-27 10:50:00 → ORD 2026-11-27 12:25:00; layover at ORD: 195 minutes.
    • UA970: ORD 2026-11-27 15:40:00 → FCO 2026-11-28 07:45:00.
  • United Airlines UA971 / UA4474: FCO 2026-12-04 09:45:00 → STL 2026-12-04 17:13:00; 1 stop(s) via ORD; 868 minutes. Local airport times.
    • UA971: FCO 2026-12-04 09:45:00 → ORD 2026-12-04 13:10:00; layover at ORD: 145 minutes.
    • UA4474: ORD 2026-12-04 15:35:00 → STL 2026-12-04 17:13:00.

2026-11-27 → 2026-12-04 · $975.00

  • Delta Air Lines DL1102 / DL66: STL 2026-11-27 14:31:00 → FCO 2026-11-28 11:20:00; 1 stop(s) via ATL; 829 minutes. Local airport times.
    • DL1102: STL 2026-11-27 14:31:00 → ATL 2026-11-27 17:05:00; layover at ATL: 175 minutes.
    • DL66: ATL 2026-11-27 20:00:00 → FCO 2026-11-28 11:20:00.
  • Delta Air Lines DL207 / DL2822: FCO 2026-12-04 10:00:00 → STL 2026-12-04 17:20:00; 1 stop(s) via DTW; 860 minutes. Local airport times.
    • DL207: FCO 2026-12-04 10:00:00 → DTW 2026-12-04 14:30:00; layover at DTW: 123 minutes.
    • DL2822: DTW 2026-12-04 16:33:00 → STL 2026-12-04 17:20:00.

2026-11-27 → 2026-12-04 · $975.00

  • Delta Air Lines DL1371 / DL206: STL 2026-11-27 14:17:00 → FCO 2026-11-28 09:35:00; 1 stop(s) via DTW; 738 minutes. Local airport times.
    • DL1371: STL 2026-11-27 14:17:00 → DTW 2026-11-27 16:53:00; layover at DTW: 112 minutes.
    • DL206: DTW 2026-11-27 18:45:00 → FCO 2026-11-28 09:35:00.
  • Delta Air Lines DL207 / DL2822: FCO 2026-12-04 10:00:00 → STL 2026-12-04 17:20:00; 1 stop(s) via DTW; 860 minutes. Local airport times.
    • DL207: FCO 2026-12-04 10:00:00 → DTW 2026-12-04 14:30:00; layover at DTW: 123 minutes.
    • DL2822: DTW 2026-12-04 16:33:00 → STL 2026-12-04 17:20:00.

More dates for this route